diff --git "a/demonstrations/apfyesq/axtrees/page-59-0.json" "b/demonstrations/apfyesq/axtrees/page-59-0.json"
new file mode 100644--- /dev/null
+++ "b/demonstrations/apfyesq/axtrees/page-59-0.json"
@@ -0,0 +1 @@
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In its modern form, biotechnology uses the techniques of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology is a set of techniques by which human beings modify living things or use them as tools. In its modern form, biotechnology uses the techniques of "}}]}, "properties": [], "parentId": "552", "childIds": [], "backendDOMNodeId": 400}, {"nodeId": "1045", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "molecular biology", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "molecular biology"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "552", "childIds": ["2236"], "backendDOMNodeId": 401, "browsergym_id": "d7444997-04fb-4c29"}, {"nodeId": "1046", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " to understand and manipulate the basic building blocks of living things. The earliest biotechnology, however, was the selective breeding of plants and animals to improve their food value. This was followed in time by the use of yeast to make bread, wine, and beer. These early forms of biotechnology began about ten thousand years ago and lie at the basis of human ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " to understand and manipulate the basic building blocks of living things. The earliest biotechnology, however, was the selective breeding of plants and animals to improve their food value. This was followed in time by the use of yeast to make bread, wine, and beer. 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It is doubtful that, at the outset, the first biotechnologists understood the effects of their actions, and so the reason for their persistence in pursuing, for example, selective breeding over the hundreds of generations necessary to show much advantage in food value, remains something of a mystery.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " from small bands of hunter-gatherers to large, settled communities, cities, and nations, giving rise, in turn, to writing and other technologies. It is doubtful that, at the outset, the first biotechnologists understood the effects of their actions, and so the reason for their persistence in pursuing, for example, selective breeding over the hundreds of generations necessary to show much advantage in food value, remains something of a mystery."}}]}, "properties": [], "parentId": "552", "childIds": [], "backendDOMNodeId": 406}, {"nodeId": "1049", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The world's historic religions emerged within the context of agriculture and primitive biotechnology, and as one might expect they are at home in that context, for instance through their affirmation of agricultural festivals. In addition, ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The world's historic religions emerged within the context of agriculture and primitive biotechnology, and as one might expect they are at home in that context, for instance through their affirmation of agricultural festivals. 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The curse makes nature at once historic, disordered, both friendly and hostile to human life, and open to improvement through human work. These effects fall especially on human agriculture and childbirth, both of which are focal areas of biotechnology.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " took the view that nature itself has a history, according to which, nature originally was a perfectly ordered garden, but as a result of human refusal to live within limits, nature was cursed or disordered by its creator. The curse makes nature at once historic, disordered, both friendly and hostile to human life, and open to improvement through human work. 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The discovery that units of hereditary information, or genes, reside in cells in a long molecule called deoxyribonucleic acid (or DNA) led to an understanding of the structure of DNA and the technology to manipulate it. Biotechnology is no longer limited to the genes found in nature or to those that could be moved within a species by breeding. Bioengineers can move genes from one species to another, from bacteria to human beings, and they can modify them within organisms.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " that established the technological basis for modern biotechnology. The discovery that units of hereditary information, or genes, reside in cells in a long molecule called deoxyribonucleic acid (or DNA) led to an understanding of the structure of DNA and the technology to manipulate it. Biotechnology is no longer limited to the genes found in nature or to those that could be moved within a species by breeding. 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Within two decades, this discovery opened the pathway to the knowledge of the socalled genetic alphabet or code of chemical bases that carry genetic information, an understanding of the relationship between that code and the proteins that result from it, and the ability to modify these structures and processes (", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " (b. 1928) is but one key step in the story of molecular biology. 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This technique, known as ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " was joined with genetic testing, allowing physicians to work with couples at risk for a genetic disease by offering them the option of conceiving multiple embryos, screening them for disease before implantation, and implanting only those that were not likely to develop the disease. 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The ground for this objection is that the human embryo must be shown the respect due human life, all the more so because it is weak and vulnerable. It is permissible to treat the embryo as a patient, but not to harm it or discard it in order to treat infertility or to benefit another. The usual counterargument is to reject the view that the embryo should be respected as a human life or a person.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", Jewish, and Protestant theologians, but is rejected by Orthodox Christians and in official Catholic statements. The ground for this objection is that the human embryo must be shown the respect due human life, all the more so because it is weak and vulnerable. It is permissible to treat the embryo as a patient, but not to harm it or discard it in order to treat infertility or to benefit another. The usual counterargument is to reject the view that the embryo should be respected as a human life or a person."}}]}, "properties": [], "parentId": "561", "childIds": [], "backendDOMNodeId": 495}, {"nodeId": "1102", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "562", "childIds": ["2261"], "backendDOMNodeId": 497, "browsergym_id": "365238e9-3568-436f"}, {"nodeId": "1103", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The significance of stem cells and cloning", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The significance of stem cells and cloning"}}]}, "properties": [], "parentId": "564", "childIds": [], "backendDOMNodeId": 502}, {"nodeId": "1104", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Developments in cloning and in the science and technology of stem cells offer additional tools for biotechnology. In popular understanding, cloning is usually seen as a technique of reproduction, and of course it does have that potential. The birth of Dolly, the cloned sheep, announced in 1997, was a surprising achievement that suggests that any mammal, including human beings, can be created from a cell taken from a previously existing individual. Many who accept reproductive technology generally, including such techniques as in vitro fertilization, found themselves opposing human reproductive cloning, but they are not sure how to distinguish between the two in religiously or morally compelling ways. With few exceptions, however, religious institutions and leaders from all faith traditions have opposed human reproductive cloning, if only because the issues of safety seem insurmountable for the foreseeable future. At the same time, almost no one has addressed the religious or moral implications of the use of reproductive cloning for mammals other than human beings, although it has been suggested that it would not be wise or appropriate to use the technique to produce large herds of livestock for food because of the risk of a pathogen destroying the entire herd.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Developments in cloning and in the science and technology of stem cells offer additional tools for biotechnology. In popular understanding, cloning is usually seen as a technique of reproduction, and of course it does have that potential. The birth of Dolly, the cloned sheep, announced in 1997, was a surprising achievement that suggests that any mammal, including human beings, can be created from a cell taken from a previously existing individual. Many who accept reproductive technology generally, including such techniques as in vitro fertilization, found themselves opposing human reproductive cloning, but they are not sure how to distinguish between the two in religiously or morally compelling ways. With few exceptions, however, religious institutions and leaders from all faith traditions have opposed human reproductive cloning, if only because the issues of safety seem insurmountable for the foreseeable future. At the same time, almost no one has addressed the religious or moral implications of the use of reproductive cloning for mammals other than human beings, although it has been suggested that it would not be wise or appropriate to use the technique to produce large herds of livestock for food because of the risk of a pathogen destroying the entire herd."}}]}, "properties": [], "parentId": "565", "childIds": [], "backendDOMNodeId": 504}, {"nodeId": "1105", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "566", "childIds": ["2262"], "backendDOMNodeId": 506, "browsergym_id": "8b01b6d0-2f9f-4d45"}, {"nodeId": "1106", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "567", "childIds": [], "backendDOMNodeId": 796, "browsergym_id": "799ff17e-7fb2-45a7"}, {"nodeId": "1107", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The technique used to create Dolly", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The technique used to create Dolly"}}]}, "properties": [], "parentId": "568", "childIds": [], "backendDOMNodeId": 798}, {"nodeId": "1108", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "568", "childIds": ["2263"], "backendDOMNodeId": 799, "browsergym_id": "a8ec8ccf-c9b6-488c"}, {"nodeId": "1109", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "the transfer of the nuclear DNA from an adult cell to an egg, thereby creating an embryo and starting it through its own developmental process", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "the transfer of the nuclear DNA from an adult cell to an egg, thereby creating an embryo and starting it through its own developmental process"}}]}, "properties": [], "parentId": "568", "childIds": [], "backendDOMNodeId": 802}, {"nodeId": "1110", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "568", "childIds": ["2264"], "backendDOMNodeId": 803, "browsergym_id": "46254926-75f5-4437"}, {"nodeId": "1111", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "can serve purposes other than reproduction, and it is these other uses that are especially interesting to biotechnology. Of particular interest is the joining of the nuclear transfer technique with the use of embryonic stem cells to treat human disease. In 1998, researchers announced success in deriving human embryonic stem cells from donated embryos. These cells show promise for treating many diseases. Once derived, they seem to be capable of being cultured indefinitely, dividing and doubling in number about every thirty hours. As of 2002, researchers have some confidence that these cells can be implanted in the human body at the site of disease or injury, where they can proliferate and develop further, and thereby take up the function of cells that were destroyed or impaired.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "can serve purposes other than reproduction, and it is these other uses that are especially interesting to biotechnology. Of particular interest is the joining of the nuclear transfer technique with the use of embryonic stem cells to treat human disease. In 1998, researchers announced success in deriving human embryonic stem cells from donated embryos. These cells show promise for treating many diseases. Once derived, they seem to be capable of being cultured indefinitely, dividing and doubling in number about every thirty hours. As of 2002, researchers have some confidence that these cells can be implanted in the human body at the site of disease or injury, where they can proliferate and develop further, and thereby take up the function of cells that were destroyed or impaired."}}]}, "properties": [], "parentId": "568", "childIds": [], "backendDOMNodeId": 806}, {"nodeId": "1112", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Stem cells, of course, can be derived from sources other than the embryo, and research is underway to discover the promise of stem cells derived from alternative sources. There are two advantages in using these other sources. First, no embryos are destroyed in deriving these cells. For anyone who sets a high standard of protection for the human embryo, the destruction of the embryo calls into question the morality of any use of embryonic stem cells. Second, the use of stem cells from sources other than an embryo may mean that in time, medical researchers will learn how to derive healing cells from the patient's own body. The advantage here is that these cells, when implanted, will not be rejected by the patient's immune system. Embryonic stem cells, which may have advantages in terms of their developmental plasticity, are decidedly problematic because of the immune response.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Stem cells, of course, can be derived from sources other than the embryo, and research is underway to discover the promise of stem cells derived from alternative sources. There are two advantages in using these other sources. First, no embryos are destroyed in deriving these cells. For anyone who sets a high standard of protection for the human embryo, the destruction of the embryo calls into question the morality of any use of embryonic stem cells. Second, the use of stem cells from sources other than an embryo may mean that in time, medical researchers will learn how to derive healing cells from the patient's own body. The advantage here is that these cells, when implanted, will not be rejected by the patient's immune system. Embryonic stem cells, which may have advantages in terms of their developmental plasticity, are decidedly problematic because of the immune response."}}]}, "properties": [], "parentId": "569", "childIds": [], "backendDOMNodeId": 808}, {"nodeId": "1113", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "One way to eliminate the immune response is to use nuclear transfer to create an embryo for the patient, harvesting stem cells from that embryo (thereby destroying it) and implanting these cells in the patient. Because they bear the patient's DNA, they should not be rejected. This approach is medically complicated, however, and involves the morally problematic step of creating an embryo to be destroyed for the benefit of another.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "One way to eliminate the immune response is to use nuclear transfer to create an embryo for the patient, harvesting stem cells from that embryo (thereby destroying it) and implanting these cells in the patient. Because they bear the patient's DNA, they should not be rejected. This approach is medically complicated, however, and involves the morally problematic step of creating an embryo to be destroyed for the benefit of another."}}]}, "properties": [], "parentId": "571", "childIds": [], "backendDOMNodeId": 811}, {"nodeId": "1114", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Nonhuman applications", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Nonhuman applications"}}]}, "properties": [], "parentId": "573", "childIds": [], "backendDOMNodeId": 815}, {"nodeId": "1115", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "As a result of the developments in the underlying science and technologies, biotechnology is able to modify any form of life in ways that seem to be limited only by the imagination or the market. Biotechnology has produced genetically modified microorganisms for purposes ranging from toxic waste clean-up to the production of medicine. For example, by inserting a human gene into a bacterium that is grown in bulk, biotechnology is able to create a living factory of organisms that have been engineered to make a specific human protein. Such technologies may also be used to enhance the virulence of organisms, to create weapons for bioterrorism, or to look for means of defense against such weapons. Aside from obvious concerns about weapons development, religious institutions and scholars have not objected to these uses of biotechnology, although some Protestant groups question the need for patents, especially when sought for specific genes.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "As a result of the developments in the underlying science and technologies, biotechnology is able to modify any form of life in ways that seem to be limited only by the imagination or the market. Biotechnology has produced genetically modified microorganisms for purposes ranging from toxic waste clean-up to the production of medicine. For example, by inserting a human gene into a bacterium that is grown in bulk, biotechnology is able to create a living factory of organisms that have been engineered to make a specific human protein. Such technologies may also be used to enhance the virulence of organisms, to create weapons for bioterrorism, or to look for means of defense against such weapons. Aside from obvious concerns about weapons development, religious institutions and scholars have not objected to these uses of biotechnology, although some Protestant groups question the need for patents, especially when sought for specific genes."}}]}, "properties": [], "parentId": "574", "childIds": [], "backendDOMNodeId": 817}, {"nodeId": "1116", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Plants, perhaps the first organisms modified by the earliest biotechnology, remain the subject of intense efforts. Around the year 2000, major advances were made in plant genome research, leading to the possibility that the full gene system of some plant species can be studied in detail, and the ways in which plants respond to their environment may be understood as never before. Some attention is given to plants for pharmaceutical purposes, but the primary interest of biotechnology in plants is to improve their value and efficiency as sources of food. For instance, attempts have been made to increase the protein value of plants like rice. The dependence of farm plants on fertilizer and pesticides may also be reduced using biotechnology to engineer plants that, for instance, are resistant to certain insects.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Plants, perhaps the first organisms modified by the earliest biotechnology, remain the subject of intense efforts. Around the year 2000, major advances were made in plant genome research, leading to the possibility that the full gene system of some plant species can be studied in detail, and the ways in which plants respond to their environment may be understood as never before. Some attention is given to plants for pharmaceutical purposes, but the primary interest of biotechnology in plants is to improve their value and efficiency as sources of food. For instance, attempts have been made to increase the protein value of plants like rice. The dependence of farm plants on fertilizer and pesticides may also be reduced using biotechnology to engineer plants that, for instance, are resistant to certain insects."}}]}, "properties": [], "parentId": "576", "childIds": [], "backendDOMNodeId": 820}, {"nodeId": "1117", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In the 1990s, the expanding use of genetically modified plants in agriculture was met with growing concerns about their effects on health and on the environment. Adding proteins to plants by altering their genes might cause health problems for at least some who consume the plants, perhaps through rare allergic reactions. Genes that produce proteins harmful to some insects may cause harm to other organisms, and they might even jump from the modified farm plant to wild plants growing nearby. Furthermore, some believe that consumers have a right to avoid food that is altered by modern biotechnology, and so strict segregation and labeling must be required. Deeply held values about food and, to some extent, its religious significance underlie many of these concerns. In ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In the 1990s, the expanding use of genetically modified plants in agriculture was met with growing concerns about their effects on health and on the environment. Adding proteins to plants by altering their genes might cause health problems for at least some who consume the plants, perhaps through rare allergic reactions. Genes that produce proteins harmful to some insects may cause harm to other organisms, and they might even jump from the modified farm plant to wild plants growing nearby. Furthermore, some believe that consumers have a right to avoid food that is altered by modern biotechnology, and so strict segregation and labeling must be required. Deeply held values about food and, to some extent, its religious significance underlie many of these concerns. In "}}]}, "properties": [], "parentId": "577", "childIds": [], "backendDOMNodeId": 822}, {"nodeId": "1118", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Europe", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Europe"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "577", "childIds": ["2265"], "backendDOMNodeId": 823, "browsergym_id": "107449da-0746-4f9e"}, {"nodeId": "1119", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and the "}}]}, "properties": [], "parentId": "577", "childIds": [], "backendDOMNodeId": 825}, {"nodeId": "1120", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "United Kingdom", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "United Kingdom"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "577", "childIds": ["2266"], "backendDOMNodeId": 826, "browsergym_id": "27788afb-da43-44b2"}, {"nodeId": "1121", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", where public opposition to genetically modified food has been strong, some churches have objected to excessive reliance upon biotechnology in food production and have supported the right of consumers to choose, while at the same time recognizing that biotechnology can increase the amount and the value of food available to the world's neediest people.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", where public opposition to genetically modified food has been strong, some churches have objected to excessive reliance upon biotechnology in food production and have supported the right of consumers to choose, while at the same time recognizing that biotechnology can increase the amount and the value of food available to the world's neediest people."}}]}, "properties": [], "parentId": "577", "childIds": [], "backendDOMNodeId": 828}, {"nodeId": "1122", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Animals are also modified by biotechnology, and this raises additional concerns for animal welfare. Usually the purpose of the modification is related to human health. Biotechnologists may, for example, create animals that produce pharmaceuticals that are expressed, for instance, in milk, or they may create animal research models that mimic human disease. These modifications usually involve a change in the animal germline", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Animals are also modified by biotechnology, and this raises additional concerns for animal welfare. Usually the purpose of the modification is related to human health. Biotechnologists may, for example, create animals that produce pharmaceuticals that are expressed, for instance, in milk, or they may create animal research models that mimic human disease. These modifications usually involve a change in the animal germline"}}]}, "properties": [], "parentId": "579", "childIds": [], "backendDOMNodeId": 831}, {"nodeId": "1123", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "579", "childIds": ["2267"], "backendDOMNodeId": 832, "browsergym_id": "76c15175-5332-446b"}, {"nodeId": "1124", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "that is, they are transmissible to future generations and they affect every cell in the body. Such animals may be patented, at least in some countries. All this raises concern about what some see as the commodification of life, the creation of unnecessary suffering for the animals, and a reductionistic attitude toward nature that sees animals as nothing but raw materials that may be reshaped according to human interest.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "that is, they are transmissible to future generations and they affect every cell in the body. Such animals may be patented, at least in some countries. All this raises concern about what some see as the commodification of life, the creation of unnecessary suffering for the animals, and a reductionistic attitude toward nature that sees animals as nothing but raw materials that may be reshaped according to human interest."}}]}, "properties": [], "parentId": "579", "childIds": [], "backendDOMNodeId": 835}, {"nodeId": "1125", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Human applications", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Human applications"}}]}, "properties": [], "parentId": "581", "childIds": [], "backendDOMNodeId": 839}, {"nodeId": "1126", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "It is the human applications of biotechnology, however, that elicit the most thorough and intense religious responses. As of 2002, genetic technologies are used to screen for a wide range of genetic conditions, but treatments for these diseases are slow to develop. Screening and testing of pregnancies, newborns, and adults have become widespread in medicine, and the resulting knowledge is used to plan for and sometimes prevent the development of disease, or to terminate a pregnancy in order to prevent the birth of an infant with foreseeable health problems. Some religious bodies, especially Roman Catholic and Orthodox Christian, vigorously criticize this use of genetic testing. One particular use of prenatal testing", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "It is the human applications of biotechnology, however, that elicit the most thorough and intense religious responses. As of 2002, genetic technologies are used to screen for a wide range of genetic conditions, but treatments for these diseases are slow to develop. Screening and testing of pregnancies, newborns, and adults have become widespread in medicine, and the resulting knowledge is used to plan for and sometimes prevent the development of disease, or to terminate a pregnancy in order to prevent the birth of an infant with foreseeable health problems. Some religious bodies, especially Roman Catholic and Orthodox Christian, vigorously criticize this use of genetic testing. One particular use of prenatal testing"}}]}, "properties": [], "parentId": "582", "childIds": [], "backendDOMNodeId": 841}, {"nodeId": "1127", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "582", "childIds": ["2268"], "backendDOMNodeId": 842, "browsergym_id": "b77eb971-69bf-4a9f"}, {"nodeId": "1128", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "to identify the sex of the unborn and to abort females", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "to identify the sex of the unborn and to abort females"}}]}, "properties": [], "parentId": "582", "childIds": [], "backendDOMNodeId": 845}, {"nodeId": "1129", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "582", "childIds": ["2269"], "backendDOMNodeId": 846, "browsergym_id": "9ff2dedf-0b24-4165"}, {"nodeId": "1130", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "is thought to be widespread in cultures that put a high priority on having sons, even though it is universally criticized. It is believed that the uses of testing will grow, while the technologies to treat disease will lag behind.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "is thought to be widespread in cultures that put a high priority on having sons, even though it is universally criticized. It is believed that the uses of testing will grow, while the technologies to treat disease will lag behind."}}]}, "properties": [], "parentId": "582", "childIds": [], "backendDOMNodeId": 849}, {"nodeId": "1131", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Attempts at treatment lie along two general pathways: pharmaceuticals and ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Attempts at treatment lie along two general pathways: pharmaceuticals and "}}]}, "properties": [], "parentId": "584", "childIds": [], "backendDOMNodeId": 852}, {"nodeId": "1132", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "gene therapy", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "gene therapy"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "584", "childIds": ["2270"], "backendDOMNodeId": 853, "browsergym_id": "d6ab7b09-efca-4632"}, {"nodeId": "1133", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ". Biotechnology offers new insight into the fundamental processes of disease, either by the creation of animal models or by insight into the functions of human cells. With this understanding, researchers are able to design pharmaceutical products with precise knowledge of their molecular and cellular effects, with greater awareness of which patients will benefit, and with fewer side effects. This is leading to a revolution in pharmaceutical products and is proving to be effective in treating a range of diseases, including cancer, but at rapidly increasing costs and amidst growing concerns about access to these benefits, especially in the poorest nations.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". Biotechnology offers new insight into the fundamental processes of disease, either by the creation of animal models or by insight into the functions of human cells. With this understanding, researchers are able to design pharmaceutical products with precise knowledge of their molecular and cellular effects, with greater awareness of which patients will benefit, and with fewer side effects. This is leading to a revolution in pharmaceutical products and is proving to be effective in treating a range of diseases, including cancer, but at rapidly increasing costs and amidst growing concerns about access to these benefits, especially in the poorest nations."}}]}, "properties": [], "parentId": "584", "childIds": [], "backendDOMNodeId": 855}, {"nodeId": "1134", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Gene therapy, begun in human beings in 1990, tries to treat disease by modifying the genes that affect its development. Originally the idea was to treat the classic genetic diseases, such as Tay Sachs or ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Gene therapy, begun in human beings in 1990, tries to treat disease by modifying the genes that affect its development. Originally the idea was to treat the classic genetic diseases, such as Tay Sachs or "}}]}, "properties": [], "parentId": "585", "childIds": [], "backendDOMNodeId": 857}, {"nodeId": "1135", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "cystic fibrosis", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "cystic fibrosis"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "585", "childIds": ["2271"], "backendDOMNodeId": 858, "browsergym_id": "b37dc319-3dfd-4b2b"}, {"nodeId": "1136", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", and it is expected that in time this technique will offer some help in treating these diseases. But ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", and it is expected that in time this technique will offer some help in treating these diseases. But "}}]}, "properties": [], "parentId": "585", "childIds": [], "backendDOMNodeId": 860}, {"nodeId": "1137", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "gene therapy", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "gene therapy"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "585", "childIds": ["2272"], "backendDOMNodeId": 861, "browsergym_id": "03e5a9e7-20d7-4667"}, {"nodeId": "1138", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " will probably find far wider use in treating other diseases not usually seen as genetic because researchers have learned how genes play a role in the body's response to every disease. Modifying this response may be a pathway to novel therapies, by which the body treats itself from the molecular level. For instance, it has been shown that modified genes can trigger the regeneration of blood vessels around the heart. In time these approaches will probably be joined with stem cell techniques and with other cell technologies, giving medicine a range of new methods for modifying the body in order to regenerate cells and tissues.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " will probably find far wider use in treating other diseases not usually seen as genetic because researchers have learned how genes play a role in the body's response to every disease. Modifying this response may be a pathway to novel therapies, by which the body treats itself from the molecular level. For instance, it has been shown that modified genes can trigger the regeneration of blood vessels around the heart. In time these approaches will probably be joined with stem cell techniques and with other cell technologies, giving medicine a range of new methods for modifying the body in order to regenerate cells and tissues."}}]}, "properties": [], "parentId": "585", "childIds": [], "backendDOMNodeId": 863}, {"nodeId": "1139", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Religious opinion has generally supported gene therapy, seeing it as essentially an extension of traditional therapies. At the same time, both religious scholars and bioethicists have begun to debate the prospect that these technologies will be used not just to treat disease but to modify traits, such as athletic or mental ability, that have nothing to do with disease, perhaps to enhance these traits for competitive reasons. Many accept the idea of therapy but reject enhancement, believing that there is a significant difference between the two goals. Many scholars, however, are skeptical about whether an unambiguous distinction can be drawn, much less enforced, between therapy and enhancement. Starting down the pathway of gene therapy may mean that human genetic enhancement is likely to follow. This prospect raises religious concerns that people who can afford to do so will acquire genetic advantages that will lead to further privilege, or that people will use these technologies to accommodate rather than challenge social prejudices.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Religious opinion has generally supported gene therapy, seeing it as essentially an extension of traditional therapies. At the same time, both religious scholars and bioethicists have begun to debate the prospect that these technologies will be used not just to treat disease but to modify traits, such as athletic or mental ability, that have nothing to do with disease, perhaps to enhance these traits for competitive reasons. Many accept the idea of therapy but reject enhancement, believing that there is a significant difference between the two goals. Many scholars, however, are skeptical about whether an unambiguous distinction can be drawn, much less enforced, between therapy and enhancement. Starting down the pathway of gene therapy may mean that human genetic enhancement is likely to follow. This prospect raises religious concerns that people who can afford to do so will acquire genetic advantages that will lead to further privilege, or that people will use these technologies to accommodate rather than challenge social prejudices."}}]}, "properties": [], "parentId": "587", "childIds": [], "backendDOMNodeId": 866}, {"nodeId": "1140", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "It is also expected that these techniques will be joined with reproductive technologies, opening the prospect that future generations of humans can be modified. The prospect of such germline modification is greeted with fear and opposition by many, usually for reasons that suggest religious themes. In Europe, germline modification is generally rejected as a violation of the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "It is also expected that these techniques will be joined with reproductive technologies, opening the prospect that future generations of humans can be modified. The prospect of such germline modification is greeted with fear and opposition by many, usually for reasons that suggest religious themes. In Europe, germline modification is generally rejected as a violation of the "}}]}, "properties": [], "parentId": "588", "childIds": [], "backendDOMNodeId": 868}, {"nodeId": "1141", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "human rights", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "human rights"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "588", "childIds": ["2273"], "backendDOMNodeId": 869, "browsergym_id": "0b748452-94bf-4515"}, {"nodeId": "1142", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " of future generations, specifically the right to be born with a genome unaffected by technology. In the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " of future generations, specifically the right to be born with a genome unaffected by technology. In the "}}]}, "properties": [], "parentId": "588", "childIds": [], "backendDOMNodeId": 871}, {"nodeId": "1143", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "United States", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "United States"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "588", "childIds": ["2274"], "backendDOMNodeId": 872, "browsergym_id": "2de2d4e5-acc9-40ab"}, {"nodeId": "1144", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", the opposition is less adamant but deeply apprehensive about issues of safety and about the long-term societal impact of what are popularly called \"designer babies.\" Religious bodies have supported these concerns and have called either for total opposition or careful deliberation.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", the opposition is less adamant but deeply apprehensive about issues of safety and about the long-term societal impact of what are popularly called \"designer babies.\" Religious bodies have supported these concerns and have called either for total opposition or careful deliberation."}}]}, "properties": [], "parentId": "588", "childIds": [], "backendDOMNodeId": 874}, {"nodeId": "1145", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "How far biotechnology can go is limited by the complexities of life processes, in particular in the subtleties of interaction between DNA and the environment. Biotechnology itself helps researchers discover these subtleties, and as much as biotechnology depends upon the sciences of biology and genetics, it must be noted that the influence between technology and science is reciprocal. The ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "How far biotechnology can go is limited by the complexities of life processes, in particular in the subtleties of interaction between DNA and the environment. Biotechnology itself helps researchers discover these subtleties, and as much as biotechnology depends upon the sciences of biology and genetics, it must be noted that the influence between technology and science is reciprocal. The "}}]}, "properties": [], "parentId": "590", "childIds": [], "backendDOMNodeId": 877}, {"nodeId": "1146", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Human Genome Project", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Human Genome Project"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "590", "childIds": ["2275"], "backendDOMNodeId": 878, "browsergym_id": "17cbd9ba-5c78-4d90"}, {"nodeId": "1147", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", for instance, opened important new questions about ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", for instance, opened important new questions about "}}]}, "properties": [], "parentId": "590", "childIds": [], "backendDOMNodeId": 880}, {"nodeId": "1148", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "human evolution", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "human evolution"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "590", "childIds": ["2276"], "backendDOMNodeId": 881, "browsergym_id": "745cbc5d-8cfa-4bbd"}, {"nodeId": "1149", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and about how DNA results in proteins. Knowledge of the genomes of various species reveals that the relationship between human beings and distant species, such as single-celled or relatively simple organisms, turns out to be surprisingly close, suggesting that evolution conserves genes as species diverge.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and about how DNA results in proteins. Knowledge of the genomes of various species reveals that the relationship between human beings and distant species, such as single-celled or relatively simple organisms, turns out to be surprisingly close, suggesting that evolution conserves genes as species diverge."}}]}, "properties": [], "parentId": "590", "childIds": [], "backendDOMNodeId": 883}, {"nodeId": "1150", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Perhaps even more surprising is the way in which the Project has challenged the standard view in modern genetics of the tight relationship between each gene and its protein, the so-called dogma of one gene, one protein. It turns out that human beings have about one hundred thousand proteins but only about thirty-three thousand genes, and that genes are more elusive and dynamic than once thought. It appears that DNA sequences from various chromosomes assemble to become the functional gene, the complete template necessary to specify the protein, and that these various sequences can assemble in more than one way, leading to more than one protein. Such dynamic complexity allows some thirty-three thousand DNA coding sequences to function as the templates for one hundred thousand proteins. But this complexity, in view of the limited understanding of the processes that define it, means that the ability to modify DNA sequences may have limited success and unpredictable consequences, which should lower confidence in genetic engineering, especially when applied to human beings.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Perhaps even more surprising is the way in which the Project has challenged the standard view in modern genetics of the tight relationship between each gene and its protein, the so-called dogma of one gene, one protein. It turns out that human beings have about one hundred thousand proteins but only about thirty-three thousand genes, and that genes are more elusive and dynamic than once thought. It appears that DNA sequences from various chromosomes assemble to become the functional gene, the complete template necessary to specify the protein, and that these various sequences can assemble in more than one way, leading to more than one protein. Such dynamic complexity allows some thirty-three thousand DNA coding sequences to function as the templates for one hundred thousand proteins. But this complexity, in view of the limited understanding of the processes that define it, means that the ability to modify DNA sequences may have limited success and unpredictable consequences, which should lower confidence in genetic engineering, especially when applied to human beings."}}]}, "properties": [], "parentId": "591", "childIds": [], "backendDOMNodeId": 885}, {"nodeId": "1151", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Biotechnology is further limited by financial factors. Most biotechnology is pursued within a commercial context, and the prospect of near-term financial return must be present to support research. Biotechnology depends upon access to capital and upon legal protection for intellectual property, such as the controversial policy of granting patent protection on DNA sequences or genes and on genetically modified organisms, including mammals. This financial dependence is itself a matter of controversy, giving rise to the fear that life itself is becoming a mere commodity or that the only values are those of the market.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology is further limited by financial factors. Most biotechnology is pursued within a commercial context, and the prospect of near-term financial return must be present to support research. Biotechnology depends upon access to capital and upon legal protection for intellectual property, such as the controversial policy of granting patent protection on DNA sequences or genes and on genetically modified organisms, including mammals. This financial dependence is itself a matter of controversy, giving rise to the fear that life itself is becoming a mere commodity or that the only values are those of the market."}}]}, "properties": [], "parentId": "593", "childIds": [], "backendDOMNodeId": 888}, {"nodeId": "1152", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "A look ahead", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "A look ahead"}}]}, "properties": [], "parentId": "595", "childIds": [], "backendDOMNodeId": 892}, {"nodeId": "1153", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "There is no reason, however, to think that biotechnology has reached the limits of its powers. On the contrary, biotechnology is growing not just in the scope of its applications but in the range and power of its techniques. Biotechnology's access to the whole genomes of human beings and other species means that the dynamic action and interaction of the entire set of genes can be monitored. In one sense, the completion of full genomes ushers in what some have called post-genomic biotechnology, characterized by a new vantage point of a systematic overview of the cell and the organism. This is proving valuable, for instance, in opening new understandings of cancer as a series of mutation events within a set of cells in the body. Attention is turning, however, from the study of genes to the study of proteins, which are more numerous than genes but also more dynamic, coming quickly into and out of existence in the trillions of cells of the human body according to precise temporal and spatial signals. Most human proteins are created only in a small percentage of cells, during a limited period of human development, and only in precisely regulated quantities. Studying this full set of proteins, in all its functional dynamism, is a daunting task requiring technologies that do not exist at the beginning of the twenty-first century. The systematic study of proteins, called ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "There is no reason, however, to think that biotechnology has reached the limits of its powers. On the contrary, biotechnology is growing not just in the scope of its applications but in the range and power of its techniques. Biotechnology's access to the whole genomes of human beings and other species means that the dynamic action and interaction of the entire set of genes can be monitored. In one sense, the completion of full genomes ushers in what some have called post-genomic biotechnology, characterized by a new vantage point of a systematic overview of the cell and the organism. This is proving valuable, for instance, in opening new understandings of cancer as a series of mutation events within a set of cells in the body. Attention is turning, however, from the study of genes to the study of proteins, which are more numerous than genes but also more dynamic, coming quickly into and out of existence in the trillions of cells of the human body according to precise temporal and spatial signals. Most human proteins are created only in a small percentage of cells, during a limited period of human development, and only in precisely regulated quantities. Studying this full set of proteins, in all its functional dynamism, is a daunting task requiring technologies that do not exist at the beginning of the twenty-first century. The systematic study of proteins, called "}}]}, "properties": [], "parentId": "596", "childIds": [], "backendDOMNodeId": 894}, {"nodeId": "1154", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "596", "childIds": ["2277"], "backendDOMNodeId": 895, "browsergym_id": "1ea61a0e-b93b-4381"}, {"nodeId": "1155", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " may in fact become a new international project for biology, leading in time to a profound expansion of the powers of biotechnology.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " may in fact become a new international project for biology, leading in time to a profound expansion of the powers of biotechnology."}}]}, "properties": [], "parentId": "596", "childIds": [], "backendDOMNodeId": 897}, {"nodeId": "1156", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In time, researchers will develop powerful new methods for modifying DNA, probably with far higher precision and effectiveness than current techniques allow, and perhaps with the ability to transfer large amounts of DNA into living cells and organisms. Computer power, which is essential to undertakings like the Human Genome Project and to their application, continues to grow, along with developments such as the so-called gene chip, using DNA as an integrated part of the computing device. Advances in engineering at the very small scale, known as ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In time, researchers will develop powerful new methods for modifying DNA, probably with far higher precision and effectiveness than current techniques allow, and perhaps with the ability to transfer large amounts of DNA into living cells and organisms. Computer power, which is essential to undertakings like the Human Genome Project and to their application, continues to grow, along with developments such as the so-called gene chip, using DNA as an integrated part of the computing device. Advances in engineering at the very small scale, known as "}}]}, "properties": [], "parentId": "598", "childIds": [], "backendDOMNodeId": 900}, {"nodeId": "1157", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "598", "childIds": ["2278"], "backendDOMNodeId": 901, "browsergym_id": "e50ee60a-618b-45d1"}, {"nodeId": "1158", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " (from ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " (from "}}]}, "properties": [], "parentId": "598", "childIds": [], "backendDOMNodeId": 903}, {"nodeId": "1159", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "598", "childIds": ["2279"], "backendDOMNodeId": 904, "browsergym_id": "c80436c5-3c49-49ee"}, {"nodeId": "1160", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " a billionth of a meter), suggest that molecular scale devices may someday be used to modify biological functions at the molecular level. For instance, nanotechnology devices in quantity may be inserted into the human body to enter cells, where they might modify DNA or other molecules. In another area of research, scientists are exploring the possibility that DNA itself may be used as a computer or a data storage device. DNA is capable of storing information more efficiently than current storage media, and it may be possible to exploit this capacity.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " a billionth of a meter), suggest that molecular scale devices may someday be used to modify biological functions at the molecular level. For instance, nanotechnology devices in quantity may be inserted into the human body to enter cells, where they might modify DNA or other molecules. In another area of research, scientists are exploring the possibility that DNA itself may be used as a computer or a data storage device. DNA is capable of storing information more efficiently than current storage media, and it may be possible to exploit this capacity."}}]}, "properties": [], "parentId": "598", "childIds": [], "backendDOMNodeId": 906}, {"nodeId": "1161", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "It is impossible to predict when new techniques will be developed or what powers they will bring. It is clear, however, that new techniques will be found and that they will converge in their effectiveness to modify life. Precisely designed pharmaceutical products will be available to treat nearly every disease, often by interrupting them at the molecular level and doing so in ways that match the specific needs of the patient. Stem cells, whether derived from embryos or from patients themselves, will probably be used to regenerate nearly any tissue or cell in the body, perhaps even portions of organs, including the brain. The genes in patients' bodies will be modified, either to correct a genetic anomaly that underlies a disease or to trigger a special response in specific cells to treat a disease or injury. It is more difficult to foresee the full extent of the long-term consequences of biotechnology on nonhuman species, on the ecosystem, on colonies of life beyond ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "It is impossible to predict when new techniques will be developed or what powers they will bring. It is clear, however, that new techniques will be found and that they will converge in their effectiveness to modify life. Precisely designed pharmaceutical products will be available to treat nearly every disease, often by interrupting them at the molecular level and doing so in ways that match the specific needs of the patient. Stem cells, whether derived from embryos or from patients themselves, will probably be used to regenerate nearly any tissue or cell in the body, perhaps even portions of organs, including the brain. The genes in patients' bodies will be modified, either to correct a genetic anomaly that underlies a disease or to trigger a special response in specific cells to treat a disease or injury. It is more difficult to foresee the full extent of the long-term consequences of biotechnology on nonhuman species, on the ecosystem, on colonies of life beyond "}}]}, "properties": [], "parentId": "599", "childIds": [], "backendDOMNodeId": 908}, {"nodeId": "1162", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Earth", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Earth"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "599", "childIds": ["2280"], "backendDOMNodeId": 909, "browsergym_id": "270ba9e0-6224-43e8"}, {"nodeId": "1163", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", and on the human species itself; estimates vary in the extreme. Some suggest that through these means, human beings will engineer their own biological enhancements, perhaps becoming two or more species.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", and on the human species itself; estimates vary in the extreme. Some suggest that through these means, human beings will engineer their own biological enhancements, perhaps becoming two or more species."}}]}, "properties": [], "parentId": "599", "childIds": [], "backendDOMNodeId": 911}, {"nodeId": "1164", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The prospect of these transformations has evoked various religious responses, and scholars from many traditions have been divided in their assessments. Those who support and endorse biotechnology stress religious duties to heal the sick and feed the hungry. Most hold the view that nature is to be improved, perhaps within limits, and that human beings are authorized to modify the processes of life. Some suggest that creation is not static but progressive, and that human beings are co-creators with ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The prospect of these transformations has evoked various religious responses, and scholars from many traditions have been divided in their assessments. Those who support and endorse biotechnology stress religious duties to heal the sick and feed the hungry. Most hold the view that nature is to be improved, perhaps within limits, and that human beings are authorized to modify the processes of life. Some suggest that creation is not static but progressive, and that human beings are co-creators with "}}]}, "properties": [], "parentId": "601", "childIds": [], "backendDOMNodeId": 914}, {"nodeId": "1165", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "God", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "God"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "601", "childIds": ["2281"], "backendDOMNodeId": 915, "browsergym_id": "c4b1f3e9-ea83-4651"}, {"nodeId": "1166", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " in the achievement of its full promise.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " in the achievement of its full promise."}}]}, "properties": [], "parentId": "601", "childIds": [], "backendDOMNodeId": 917}, {"nodeId": "1167", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Others believe biotechnology will pervert nature and undermine human existence and its moral basis. They argue, for instance, that genetic modifications of offspring will damage the relationship between parents and children by reducing children to objects, products of technology, and limit their freedom to grow into persons in relationship with others. Some warn that saying yes to biotechnology now will make it impossible to say no in the future. Still others suggest that the point is not to try to stop biotechnology but to learn to live humanely with its powers, and as much as possible to steer it away from selfish or excessive uses and toward compassionate and just ends.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Others believe biotechnology will pervert nature and undermine human existence and its moral basis. 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"backendDOMNodeId": 1185, "browsergym_id": "3a54df4a-a09f-4089"}, {"nodeId": "1219", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " Biotechnology, in its broadest sense, is the use of biological systems to carry out technical processes. Food biotechnology uses genetic methods to enhance food properties and to improve production, and in particular uses direct (rather than random) strategies to modify genes that are responsible for traits such as a vegetable's nutritional content. Using modern biotechnology, scientists can move genes for valuable traits from one plant into another plant. This way, they can make a plant taste or look better, be more nutritious, protect itself from insects, produce more food, or survive and prosper in inhospitable environments, for example, by incorporating tolerance to increased soil salinity. Simply put, food biotechnology is the practice of directing genetic changes in organisms that produce food in order to make a better product.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " Biotechnology, in its broadest sense, is the use of biological systems to carry out technical processes. Food biotechnology uses genetic methods to enhance food properties and to improve production, and in particular uses direct (rather than random) strategies to modify genes that are responsible for traits such as a vegetable's nutritional content. Using modern biotechnology, scientists can move genes for valuable traits from one plant into another plant. This way, they can make a plant taste or look better, be more nutritious, protect itself from insects, produce more food, or survive and prosper in inhospitable environments, for example, by incorporating tolerance to increased soil salinity. Simply put, food biotechnology is the practice of directing genetic changes in organisms that produce food in order to make a better product."}}]}, "properties": [], "parentId": "642", "childIds": [], "backendDOMNodeId": 1187}, {"nodeId": "1220", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In nature, plants produce their own chemical defenses to ward off disease and insects thereby reducing the need for insecticide sprays. Biotechnology is often used to enhance these defenses. Some improvements are crop specific. For example, potatoes with a higher starch content will absorb less oil when frying, and tomatoes with delayed ripening qualities will have improved taste and freshness.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In nature, plants produce their own chemical defenses to ward off disease and insects thereby reducing the need for insecticide sprays. Biotechnology is often used to enhance these defenses. Some improvements are crop specific. For example, potatoes with a higher starch content will absorb less oil when frying, and tomatoes with delayed ripening qualities will have improved taste and freshness."}}]}, "properties": [], "parentId": "644", "childIds": [], "backendDOMNodeId": 1190}, {"nodeId": "1221", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Paving the Way to Modern Biotechnology", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Paving the Way to Modern Biotechnology"}}]}, "properties": [], "parentId": "645", "childIds": [], "backendDOMNodeId": 1192}, {"nodeId": "1222", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Advances in science over many years account for what we know and are able to accomplish with modern biotechnology and food production. A brief review of genetics and biochemistry is useful in evaluating the role of biotechnology in our food supply.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Advances in science over many years account for what we know and are able to accomplish with modern biotechnology and food production. A brief review of genetics and biochemistry is useful in evaluating the role of biotechnology in our food supply."}}]}, "properties": [], "parentId": "646", "childIds": [], "backendDOMNodeId": 1194}, {"nodeId": "1223", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Proteins are composed of various combinations of amino acids. They are essential for life", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Proteins are composed of various combinations of amino acids. They are essential for life"}}]}, "properties": [], "parentId": "647", "childIds": [], "backendDOMNodeId": 1196}, {"nodeId": "1224", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "647", "childIds": ["2302"], "backendDOMNodeId": 1197, "browsergym_id": "6695da88-0579-4bca"}, {"nodeId": "1225", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "both for an organism's structure, and for the metabolic reactions necessary for the organism to function. The number, kind, and order of amino acids in a specific protein determine its properties. Deoxyribonucleic acid (DNA), which is present in all the cells of all organisms, contains the information needed for cells to put amino acids in the correct order. In other words, DNA contains the genetic blueprint determining how cells in all living organisms store, duplicate, and pass information about protein structure from generation to generation.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "both for an organism's structure, and for the metabolic reactions necessary for the organism to function. The number, kind, and order of amino acids in a specific protein determine its properties. Deoxyribonucleic acid (DNA), which is present in all the cells of all organisms, contains the information needed for cells to put amino acids in the correct order. In other words, DNA contains the genetic blueprint determining how cells in all living organisms store, duplicate, and pass information about protein structure from generation to generation."}}]}, "properties": [], "parentId": "647", "childIds": [], "backendDOMNodeId": 1202}, {"nodeId": "1226", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In 1953 ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In 1953 "}}]}, "properties": [], "parentId": "649", "childIds": [], "backendDOMNodeId": 1205}, {"nodeId": "1227", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "James Watson", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "James Watson"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "649", "childIds": ["2303"], "backendDOMNodeId": 1206, "browsergym_id": "9472204b-a8ea-4bf1"}, {"nodeId": "1228", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and Francis Crick published their discovery that the molecular structure of DNA is a double helix, for which they, along with Maurice H. F. Wilkins, won a ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and Francis Crick published their discovery that the molecular structure of DNA is a double helix, for which they, along with Maurice H. F. Wilkins, won a "}}]}, "properties": [], "parentId": "649", "childIds": [], "backendDOMNodeId": 1208}, {"nodeId": "1229", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Nobel Prize", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Nobel Prize"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "649", "childIds": ["2304"], "backendDOMNodeId": 1209, "browsergym_id": "d137033c-63d3-46d1"}, {"nodeId": "1230", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " in 1962. Two strands of DNA are composed of pairs of chemicals", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " in 1962. Two strands of DNA are composed of pairs of chemicals"}}]}, "properties": [], "parentId": "649", "childIds": [], "backendDOMNodeId": 1211}, {"nodeId": "1231", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "649", "childIds": ["2305"], "backendDOMNodeId": 1212, "browsergym_id": "4a32619e-6db7-4192"}, {"nodeId": "1232", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "adenine (A) and thymine (T); and guanine (G) and cytosine (C). A segment of DNA that encodes enough information to make one protein is called a gene. It is the order of DNA's base pairs that determines specific genes that code for specific proteins, which determines individual traits.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "adenine (A) and thymine (T); and guanine (G) and cytosine (C). A segment of DNA that encodes enough information to make one protein is called a gene. It is the order of DNA's base pairs that determines specific genes that code for specific proteins, which determines individual traits."}}]}, "properties": [], "parentId": "649", "childIds": [], "backendDOMNodeId": 1217}, {"nodeId": "1233", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "By 1973 scientists had found ways to isolate individual genes, and by the 1980s, scientists could transfer single genes from one organism to another. This process, much like traditional crossbreeding, allows transferred traits to pass to future generations of the recipient organism.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "By 1973 scientists had found ways to isolate individual genes, and by the 1980s, scientists could transfer single genes from one organism to another. This process, much like traditional crossbreeding, allows transferred traits to pass to future generations of the recipient organism."}}]}, "properties": [], "parentId": "650", "childIds": [], "backendDOMNodeId": 1219}, {"nodeId": "1234", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "One Goal, Two Approaches", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "One Goal, Two Approaches"}}]}, "properties": [], "parentId": "651", "childIds": [], "backendDOMNodeId": 1221}, {"nodeId": "1235", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The objective of plant biotechnology and traditional crop breeding is the same: to improve the characteristics of seed so that the resulting plants have new, desirable traits. The primary difference between the two techniques is how the objective is achieved. Plant breeders have used traditional tools such as hybridization and crossbreeding to improve the quality and yield of their crops with a resulting wide variability in our foods. These traditional techniques resulted in several benefits, such as greatly increased crop production and improved quality of food and feed crops, which has proven beneficial to growers and producers as well as consumers through a reduction of the cost of food for consumers. However, traditional ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The objective of plant biotechnology and traditional crop breeding is the same: to improve the characteristics of seed so that the resulting plants have new, desirable traits. The primary difference between the two techniques is how the objective is achieved. Plant breeders have used traditional tools such as hybridization and crossbreeding to improve the quality and yield of their crops with a resulting wide variability in our foods. These traditional techniques resulted in several benefits, such as greatly increased crop production and improved quality of food and feed crops, which has proven beneficial to growers and producers as well as consumers through a reduction of the cost of food for consumers. 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Because of this, the sources for potential desirable traits are finite. In addition, the process of crossbreeding is very time-consuming, at times taking ten to twelve years to achieve the desired goal", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " techniques do have some limits; only plants from the same or similar species can be interbred. Because of this, the sources for potential desirable traits are finite. In addition, the process of crossbreeding is very time-consuming, at times taking ten to twelve years to achieve the desired goal"}}]}, "properties": [], "parentId": "652", "childIds": [], "backendDOMNodeId": 1226}, {"nodeId": "1238", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "652", "childIds": ["2307"], "backendDOMNodeId": 1227, "browsergym_id": "09d67a43-8ecc-4fa4"}, {"nodeId": "1239", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "and complications can arise because all genes of the two \"parent\" plants are combined together. This means that both the desirable ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "and complications can arise because all genes of the two \"parent\" plants are combined together. This means that both the desirable "}}]}, "properties": [], "parentId": "652", "childIds": [], "backendDOMNodeId": 1232}, {"nodeId": "1240", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "652", "childIds": ["2308"], "backendDOMNodeId": 1233, "browsergym_id": "5f93d21c-e833-4677"}, {"nodeId": "1241", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "undesirable traits may be expressed in the new plant. It takes a significant amount of time to remove the unwanted traits by \"back crossing\" the new plant over many generations to achieve the desired traits. These biotech methods can preserve the unique genetic composition of some crops while allowing the addition or incorporation of specific genetic traits, such as resistance to disease. However, development of transgenic crop varieties still requires a significant investment of time and resources.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "undesirable traits may be expressed in the new plant. It takes a significant amount of time to remove the unwanted traits by \"back crossing\" the new plant over many generations to achieve the desired traits. These biotech methods can preserve the unique genetic composition of some crops while allowing the addition or incorporation of specific genetic traits, such as resistance to disease. However, development of transgenic crop varieties still requires a significant investment of time and resources."}}]}, "properties": [], "parentId": "652", "childIds": [], "backendDOMNodeId": 1235}, {"nodeId": "1242", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The Many Applications of Biotechnology", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The Many Applications of Biotechnology"}}]}, "properties": [], "parentId": "654", "childIds": [], "backendDOMNodeId": 1238}, {"nodeId": "1243", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Since the earliest times, people have been using simple forms of biotechnology to improve their food supply, long before the discovery of the structure of DNA by Watson and Crick. For example, grapes and grains were modified through fermentation with microorganisms and used to make wine, beer, and leavened bread. Modern biotechnology, which uses the latest ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Since the earliest times, people have been using simple forms of biotechnology to improve their food supply, long before the discovery of the structure of DNA by Watson and Crick. For example, grapes and grains were modified through fermentation with microorganisms and used to make wine, beer, and leavened bread. Modern biotechnology, which uses the latest "}}]}, "properties": [], "parentId": "655", "childIds": [], "backendDOMNodeId": 1240}, {"nodeId": "1244", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "molecular biology", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "molecular biology"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "655", "childIds": ["2309"], "backendDOMNodeId": 1241, "browsergym_id": "030899e4-25c3-4394"}, {"nodeId": "1245", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " technology, allows us to more directly modify our foods. Whereas traditional ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " technology, allows us to more directly modify our foods. Whereas traditional "}}]}, "properties": [], "parentId": "655", "childIds": [], "backendDOMNodeId": 1243}, {"nodeId": "1246", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "plant breeding", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "plant breeding"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "655", "childIds": ["2310"], "backendDOMNodeId": 1244, "browsergym_id": "2846e2b7-acdf-485c"}, {"nodeId": "1247", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " mixes tens of thousands of genes, biotechnology allows for the transfer of a single gene, or a few select genes or traits. The most common uses thus far have been the introduction of traits that help farmers simplify crop production, reduce pesticide use in some crops, and increase profitability by reduction of crop losses to weeds, insect damage, or disease.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " mixes tens of thousands of genes, biotechnology allows for the transfer of a single gene, or a few select genes or traits. The most common uses thus far have been the introduction of traits that help farmers simplify crop production, reduce pesticide use in some crops, and increase profitability by reduction of crop losses to weeds, insect damage, or disease."}}]}, "properties": [], "parentId": "655", "childIds": [], "backendDOMNodeId": 1246}, {"nodeId": "1248", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In general, the early applications of crop biotechnology have been at points in our food supply chain where economic benefit can be gained. The following are examples of modern biotechnology where success has been achieved or is in progress.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In general, the early applications of crop biotechnology have been at points in our food supply chain where economic benefit can be gained. The following are examples of modern biotechnology where success has been achieved or is in progress."}}]}, "properties": [], "parentId": "656", "childIds": [], "backendDOMNodeId": 1248}, {"nodeId": "1249", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "657", "childIds": ["2311", "2312"], "backendDOMNodeId": 1250, "browsergym_id": "13c6369c-681f-4ebe"}, {"nodeId": "1250", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Crop losses from insect pests can cause devastating financial loss for growers and starvation in developing countries. In the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Crop losses from insect pests can cause devastating financial loss for growers and starvation in developing countries. In the "}}]}, "properties": [], "parentId": "657", "childIds": [], "backendDOMNodeId": 1254}, {"nodeId": "1251", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "United States", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "United States"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "657", "childIds": ["2313"], "backendDOMNodeId": 1255, "browsergym_id": "e9e5facd-2844-4aa9"}, {"nodeId": "1252", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and "}}]}, "properties": [], "parentId": "657", "childIds": [], "backendDOMNodeId": 1257}, {"nodeId": "1253", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Europe", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Europe"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "657", "childIds": ["2314"], "backendDOMNodeId": 1258, "browsergym_id": "ac3581e4-e863-43f9"}, {"nodeId": "1254", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", thousands of tons of pesticides are used to control insects. Using modern biotechnology, scientists and farmers have removed the need for the use of some of these chemicals. Insect-protected plants are developed by introducing a gene into a plant that produces a specific protein from a naturally occurring soil organism. ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", thousands of tons of pesticides are used to control insects. Using modern biotechnology, scientists and farmers have removed the need for the use of some of these chemicals. Insect-protected plants are developed by introducing a gene into a plant that produces a specific protein from a naturally occurring soil organism. 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The ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " is one of many bacteria naturally present in soil. This bacterium is known to be lethal to certain classes of insects, and only those organisms. 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Growing foods, such as "}}]}, "properties": [], "parentId": "657", "childIds": [], "backendDOMNodeId": 1266}, {"nodeId": "1259", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "657", "childIds": ["2317"], "backendDOMNodeId": 1267, "browsergym_id": "a6bc5354-2302-4c1e"}, {"nodeId": "1260", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " corn, can help eliminate the application of chemical pesticides and reduce the cost of bringing a crop to market. The introduction of insect-protected crops such as ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " corn, can help eliminate the application of chemical pesticides and reduce the cost of bringing a crop to market. The introduction of insect-protected crops such as "}}]}, "properties": [], "parentId": "657", "childIds": [], "backendDOMNodeId": 1269}, {"nodeId": "1261", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "657", "childIds": ["2318"], "backendDOMNodeId": 1270, "browsergym_id": "0373969a-579a-4fe6"}, {"nodeId": "1262", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " cotton has allowed reduced use of chemical pesticides. This suggests that genetically engineered food crops can also be grown with reduced use of pesticides, a development that would be welcomed by the general public.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " cotton has allowed reduced use of chemical pesticides. This suggests that genetically engineered food crops can also be grown with reduced use of pesticides, a development that would be welcomed by the general public."}}]}, "properties": [], "parentId": "657", "childIds": [], "backendDOMNodeId": 1272}, {"nodeId": "1263", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "659", "childIds": ["2319", "2320"], "backendDOMNodeId": 1275, "browsergym_id": "87a72006-a0f2-4637"}, {"nodeId": "1264", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Every year, farmers must battle weeds that compete with their crops for water, nutrients, sunlight, and space. Weeds can also harbor insects and disease. Farmers routinely use two or more different chemicals on a crop to remove both grass and broadleaf weeds. In recent years new \"broad-spectrum\" chemicals have been discovered that control all these weeds and therefore require only one application of one chemical to the crop. To provide crops with a defense against these nonselective herbicides, genes have been added to plants that render the chemicals inactive", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Every year, farmers must battle weeds that compete with their crops for water, nutrients, sunlight, and space. Weeds can also harbor insects and disease. Farmers routinely use two or more different chemicals on a crop to remove both grass and broadleaf weeds. In recent years new \"broad-spectrum\" chemicals have been discovered that control all these weeds and therefore require only one application of one chemical to the crop. To provide crops with a defense against these nonselective herbicides, genes have been added to plants that render the chemicals inactive"}}]}, "properties": [], "parentId": "659", "childIds": [], "backendDOMNodeId": 1279}, {"nodeId": "1265", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "659", "childIds": ["2321"], "backendDOMNodeId": 1280, "browsergym_id": "82f2b26d-7ad0-4af2"}, {"nodeId": "1266", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "but only in the new, herbicide-resistant crop. Many benefits come from these crops, including better and more flexible weed control for farmers, increased use of conservation tillage (involving less working of the soil and thereby decreasing erosion), and promoting the use of herbicides that have a better environmental profile (that is, that are less toxic to nontarget organisms).", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "but only in the new, herbicide-resistant crop. Many benefits come from these crops, including better and more flexible weed control for farmers, increased use of conservation tillage (involving less working of the soil and thereby decreasing erosion), and promoting the use of herbicides that have a better environmental profile (that is, that are less toxic to nontarget organisms)."}}]}, "properties": [], "parentId": "659", "childIds": [], "backendDOMNodeId": 1285}, {"nodeId": "1267", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "660", "childIds": ["2322", "2323"], "backendDOMNodeId": 1287, "browsergym_id": "6245583f-bf72-45e7"}, {"nodeId": "1268", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Many viruses, fungi, and bacteria can cause plant diseases, resulting in crop damage and loss. Researchers have had great success in developing crops that are protected from certain types of plant viruses by introducing DNA from the virus into the plant. In essence, the plants are \"vaccinated\" against specific diseases. Because most plant viruses are spread by insects, farmers can use fewer insecticides and still have healthy crops and high yields.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Many viruses, fungi, and bacteria can cause plant diseases, resulting in crop damage and loss. Researchers have had great success in developing crops that are protected from certain types of plant viruses by introducing DNA from the virus into the plant. In essence, the plants are \"vaccinated\" against specific diseases. Because most plant viruses are spread by insects, farmers can use fewer insecticides and still have healthy crops and high yields."}}]}, "properties": [], "parentId": "660", "childIds": [], "backendDOMNodeId": 1291}, {"nodeId": "1269", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "662", "childIds": ["2324", "2325"], "backendDOMNodeId": 1294, "browsergym_id": "a0803298-97b1-404b"}, {"nodeId": "1270", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "As the world population grows and industrial demand for water supplies increases, the amount of water used to irrigate crops will become more expensive or unavailable. Creating plants that can withstand long periods of drought or high salt content in soil and groundwater will help overcome these limitations. Although genetically engineered crops with enhanced drought tolerance are not yet commercially available, significant research advances are pointing the way to creating these in the future.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "As the world population grows and industrial demand for water supplies increases, the amount of water used to irrigate crops will become more expensive or unavailable. Creating plants that can withstand long periods of drought or high salt content in soil and groundwater will help overcome these limitations. Although genetically engineered crops with enhanced drought tolerance are not yet commercially available, significant research advances are pointing the way to creating these in the future."}}]}, "properties": [], "parentId": "662", "childIds": [], "backendDOMNodeId": 1298}, {"nodeId": "1271", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "663", "childIds": ["2326", "2327"], "backendDOMNodeId": 1300, "browsergym_id": "b6c97593-e62e-4fc0"}, {"nodeId": "1272", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Research into applications of biotechnology to food production covers a broad range of possibilities. 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", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "There is really little doubt that, at least in principle, the development of genetically modified organisms (GMOs) can offer many advantages. 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Plans for development of GMOs include foods that have far greater nutritional and even pharmaceutical benefit; crops that can grow in regions that currently cannot provide enough food for subsistence; and foods that are more desirable in terms of traits that the public wants. The market forces that largely determine which products are developed are complicated, and there are important trade-offs: the traits that may be needed to feed a starving world are different from the traits farmers in the United States want, and both may differ from the characteristics the paying public supports.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " have included crops that are largely of benefit to farmers and not clearly of broad public value. Plans for development of GMOs include foods that have far greater nutritional and even pharmaceutical benefit; crops that can grow in regions that currently cannot provide enough food for subsistence; and foods that are more desirable in terms of traits that the public wants. The market forces that largely determine which products are developed are complicated, and there are important trade-offs: the traits that may be needed to feed a starving world are different from the traits farmers in the United States want, and both may differ from the characteristics the paying public supports."}}]}, "properties": [], "parentId": "691", "childIds": [], "backendDOMNodeId": 1438}, {"nodeId": "1333", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Most criticisms of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Most criticisms of "}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1440}, {"nodeId": "1334", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "genetic engineering", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "genetic engineering"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "692", "childIds": ["2362"], "backendDOMNodeId": 1441, "browsergym_id": "62beca06-585a-4948"}, {"nodeId": "1335", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " focus on food safety and environmental impacts. What impact will GMOs have on the health of those who eat them? Will some individuals develop allergic reactions? The ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " focus on food safety and environmental impacts. What impact will GMOs have on the health of those who eat them? Will some individuals develop allergic reactions? The "}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1443}, {"nodeId": "1336", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "new technology", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "new technology"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "692", "childIds": ["2363"], "backendDOMNodeId": 1444, "browsergym_id": "2ca34ded-2a6d-43f0"}, {"nodeId": "1337", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " makes it possible to cross species barriers with impunity. A scare over StarLink corn is instructive of this kind of problem. \"", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " makes it possible to cross species barriers with impunity. A scare over StarLink corn is instructive of this kind of problem. \""}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1446}, {"nodeId": "1338", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "692", "childIds": ["2364"], "backendDOMNodeId": 1447, "browsergym_id": "b6b0b752-f0a7-42ec"}, {"nodeId": "1339", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " corn,\" a common GMO, includes a gene from ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " corn,\" a common GMO, includes a gene from "}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1449}, {"nodeId": "1340", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "692", "childIds": ["2365"], "backendDOMNodeId": 1450, "browsergym_id": "d77425ff-d1cd-47d1"}, {"nodeId": "1341", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", which produces a pesticide that kills the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", which produces a pesticide that kills the "}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1452}, {"nodeId": "1342", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "European corn borer", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "European corn borer"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "692", "childIds": ["2366"], "backendDOMNodeId": 1453, "browsergym_id": "2603f746-10ca-4c3c"}, {"nodeId": "1343", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ". StarLink is a variety of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". StarLink is a variety of "}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1455}, {"nodeId": "1344", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "692", "childIds": ["2367"], "backendDOMNodeId": 1456, "browsergym_id": "57e7a4e3-83e2-4294"}, {"nodeId": "1345", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " corn that includes a protein (Cry9C) that does not break down as easily in the body, which increases the risk of allergic reactions in some people (though there are no verified cases of this). StarLink corn was approved for animal feed but not for human consumption. Unfortunately it is difficult if not impossible to keep the food supply for animals and humans separate. The result has been the discovery of small amounts of StarLink corn throughout the food supply. (Of course, there is also the question whether a small trace of Cry9C in a fast-food taco is the greatest health problem involved in such a meal.)", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " corn that includes a protein (Cry9C) that does not break down as easily in the body, which increases the risk of allergic reactions in some people (though there are no verified cases of this). StarLink corn was approved for animal feed but not for human consumption. Unfortunately it is difficult if not impossible to keep the food supply for animals and humans separate. The result has been the discovery of small amounts of StarLink corn throughout the food supply. (Of course, there is also the question whether a small trace of Cry9C in a fast-food taco is the greatest health problem involved in such a meal.)"}}]}, "properties": [], "parentId": "692", "childIds": [], "backendDOMNodeId": 1458}, {"nodeId": "1346", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "A second set of concerns arises over the environmental impact of GMOs. There are several different concerns. First, there are worries about gene flow. The same genes that may one day make it possible for plants to grow in poor, salty soil or in relatively arid regions could create an ecological nightmare by allowing these crops to spread beyond their normal range as a result of the gene(s) that have been transferred into the crop itself, or if those same genes should be introduced to other plants. This can happen through outcrossing between the GMOs and closely related plants. For example, GM wheat could cross with native grasses in ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "A second set of concerns arises over the environmental impact of GMOs. There are several different concerns. First, there are worries about gene flow. The same genes that may one day make it possible for plants to grow in poor, salty soil or in relatively arid regions could create an ecological nightmare by allowing these crops to spread beyond their normal range as a result of the gene(s) that have been transferred into the crop itself, or if those same genes should be introduced to other plants. This can happen through outcrossing between the GMOs and closely related plants. For example, GM wheat could cross with native grasses in "}}]}, "properties": [], "parentId": "693", "childIds": [], "backendDOMNodeId": 1460}, {"nodeId": "1347", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "South America", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "South America"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "693", "childIds": ["2368"], "backendDOMNodeId": 1461, "browsergym_id": "39be15d0-9e85-4e82"}, {"nodeId": "1348", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " to alter the makeup of the ecosystem and potentially create \"super weeds,\" a possibility that has raised concerns in the \"Wheat Belt\" of the United States and elsewhere. Even in the absence of gene flow, the GMOs themselves could become super weeds (or the animal equivalent) as a result of the traits that make them better suited to new habitats. The environmental trade-off for technology that makes it possible to produce sustainable agriculture or aquaculture in regions where it cannot \"naturally\" flourish is the significant risk of loss of biodiversity and the unchecked spread of plants or animals into unintended regions. (The argument is made, however, that biotechnology can be used to increase yields on the land that is currently used for agricultural production, allowing nonfarm land to be retained as forests and reserves and thereby conserve biodiversity.)", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " to alter the makeup of the ecosystem and potentially create \"super weeds,\" a possibility that has raised concerns in the \"Wheat Belt\" of the United States and elsewhere. Even in the absence of gene flow, the GMOs themselves could become super weeds (or the animal equivalent) as a result of the traits that make them better suited to new habitats. The environmental trade-off for technology that makes it possible to produce sustainable agriculture or aquaculture in regions where it cannot \"naturally\" flourish is the significant risk of loss of biodiversity and the unchecked spread of plants or animals into unintended regions. (The argument is made, however, that biotechnology can be used to increase yields on the land that is currently used for agricultural production, allowing nonfarm land to be retained as forests and reserves and thereby conserve biodiversity.)"}}]}, "properties": [], "parentId": "693", "childIds": [], "backendDOMNodeId": 1463}, {"nodeId": "1349", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In addition to these concerns over the ecosystem and the creation of superweeds, there is a worry over the potential impact of some GMOs on nontarget organisms. ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In addition to these concerns over the ecosystem and the creation of superweeds, there is a worry over the potential impact of some GMOs on nontarget organisms. 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This raised the fear that these engineered crops could kill butterflies and other nontarget organisms in addition to the corn borer. The consensus from subsequent field research is that ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "corn could kill the larvae of monarch butterflies that ingested it. This raised the fear that these engineered crops could kill butterflies and other nontarget organisms in addition to the corn borer. 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Nevertheless, the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "loss of habitat in Mexico, where the butterflies overwinter, is a more serious threat. Nevertheless, the "}}]}, "properties": [], "parentId": "694", "childIds": [], "backendDOMNodeId": 1480}, {"nodeId": "1358", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "694", "childIds": ["2373"], "backendDOMNodeId": 1481, "browsergym_id": "854d051b-0895-4299"}, {"nodeId": "1359", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " corn", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " corn"}}]}, "properties": [], "parentId": "694", "childIds": [], "backendDOMNodeId": 1483}, {"nodeId": "1360", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "694", "childIds": ["2374"], "backendDOMNodeId": 1484, "browsergym_id": "6b838a13-8d22-4333"}, {"nodeId": "1361", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "butterfly issue showed that it is not always possible to predict the consequences that may arise from the introduction of these crops.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "butterfly issue showed that it is not always possible to predict the consequences that may arise from the introduction of these crops."}}]}, "properties": [], "parentId": "694", "childIds": [], "backendDOMNodeId": 1489}, {"nodeId": "1362", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Genetically engineered microorganisms present even greater environmental and health concerns. It will soon be possible to engineer bacteria and viruses to produce deadly pathogens. This could well open a new era in biological weapons in addition to the environmental problems that could result from the release of organisms into the environment. The environmental assessment of the widespread introduction of engineered microorganisms has only barely begun to receive attention (Cho et al., 1999).", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Genetically engineered microorganisms present even greater environmental and health concerns. It will soon be possible to engineer bacteria and viruses to produce deadly pathogens. This could well open a new era in biological weapons in addition to the environmental problems that could result from the release of organisms into the environment. The environmental assessment of the widespread introduction of engineered microorganisms has only barely begun to receive attention (Cho et al., 1999)."}}]}, "properties": [], "parentId": "695", "childIds": [], "backendDOMNodeId": 1491}, {"nodeId": "1363", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "These concerns are exacerbated by some inadequacies in the regulatory framework for GMOs. There is a growing sense that the Food and Drug Administration, the U.S. Department of Agriculture, and the Environmental Protection Agency are not sufficiently rigorous or consistent in how they regulate GMOs and that there should be a single set of standards, including a mandatory environmental assessment. The opposition to GMOs in Europe is much more widespread than in the United States, and the single most important factor for the differences between European and American attitudes is the level of confidence in the regulatory institutions that protect the food supply. After \"mad cow disease,\" Europeans do not trust their governments to provide safe food. A similar loss in confidence among U.S. consumers could have a similar effect. In spite of these concerns, however, there have so far been no documented food safety problems resulting from the introduction of GM crops in the mid-1990s and their large-scale consumption by the American public. There have also been no ecological disasters, although the time since their introduction has been too brief for the absence of disaster to be very meaningful. In some crops, notably in ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "These concerns are exacerbated by some inadequacies in the regulatory framework for GMOs. There is a growing sense that the Food and Drug Administration, the U.S. Department of Agriculture, and the Environmental Protection Agency are not sufficiently rigorous or consistent in how they regulate GMOs and that there should be a single set of standards, including a mandatory environmental assessment. The opposition to GMOs in Europe is much more widespread than in the United States, and the single most important factor for the differences between European and American attitudes is the level of confidence in the regulatory institutions that protect the food supply. After \"mad cow disease,\" Europeans do not trust their governments to provide safe food. A similar loss in confidence among U.S. consumers could have a similar effect. In spite of these concerns, however, there have so far been no documented food safety problems resulting from the introduction of GM crops in the mid-1990s and their large-scale consumption by the American public. There have also been no ecological disasters, although the time since their introduction has been too brief for the absence of disaster to be very meaningful. 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Yet authorities do not agree on a single definition of this term. Sometimes, writers have limited the term to techniques used to modify living organisms and, in some instances, the creation of entirely new kinds of organisms.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Few developments in science have had the potential for such profound impact on research, technology, and society in general as has biotechnology. Yet authorities do not agree on a single definition of this term. Sometimes, writers have limited the term to techniques used to modify living organisms and, in some instances, the creation of entirely new kinds of organisms."}}]}, "properties": [], "parentId": "708", "childIds": [], "backendDOMNodeId": 1687}, {"nodeId": "1379", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In most cases, however, a broader, more general definition is used. The Industrial Biotechnology Association, for example, uses the term to refer to any \"development of products by a biological process.\" These products may indeed be organisms or they may be cells, components of cells, or individual and specific ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In most cases, however, a broader, more general definition is used. The Industrial Biotechnology Association, for example, uses the term to refer to any \"development of products by a biological process.\" These products may indeed be organisms or they may be cells, components of cells, or individual and specific "}}]}, "properties": [], "parentId": "709", "childIds": [], "backendDOMNodeId": 1689}, {"nodeId": "1380", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "709", "childIds": ["2388"], "backendDOMNodeId": 1690, "browsergym_id": "54e837b6-e817-4d7b"}, {"nodeId": "1381", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " . A somewhat more detailed definition is that of the European Federation of Biotechnology, which defines biotechnology as the \"integrated use of biochemistry, microbiology, and engineering sciences in order to achieve technological (industrial) application of the capabilities of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " . A somewhat more detailed definition is that of the European Federation of Biotechnology, which defines biotechnology as the \"integrated use of biochemistry, microbiology, and engineering sciences in order to achieve technological (industrial) application of the capabilities of "}}]}, "properties": [], "parentId": "709", "childIds": [], "backendDOMNodeId": 1692}, {"nodeId": "1382", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "709", "childIds": ["2389"], "backendDOMNodeId": 1693, "browsergym_id": "a030832a-a296-4bd1"}, {"nodeId": "1383", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " , cultured tissue cells, and parts thereof.\"", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " , cultured tissue cells, and parts thereof.\""}}]}, "properties": [], "parentId": "709", "childIds": [], "backendDOMNodeId": 1695}, {"nodeId": "1384", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "By almost any definition, biotechnology has been used by humans for thousands of years, long before modern science existed. Some of the oldest manufacturing processes known to humankind make use of biotechnology. Beer, wine, and breadmaking, for example, all occur because of the process of fermentation. During fermentation, microorganisms such as yeasts, molds, and bacteria are mixed with natural products which they use as food. In the case of wine-making, for example, yeasts live on the sugars found in some type of fruit juice, most commonly, grape juice. They digest those sugars and produce two new products, alcohol and ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "By almost any definition, biotechnology has been used by humans for thousands of years, long before modern science existed. Some of the oldest manufacturing processes known to humankind make use of biotechnology. Beer, wine, and breadmaking, for example, all occur because of the process of fermentation. During fermentation, microorganisms such as yeasts, molds, and bacteria are mixed with natural products which they use as food. In the case of wine-making, for example, yeasts live on the sugars found in some type of fruit juice, most commonly, grape juice. 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In breadmaking, the products of fermentation are responsible for the wonderful odor (the alcohol) and texture (the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The alcoholic beverages produced by this process have been, for better or worse, a mainstay of human civilization for untold centuries. 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Cheese and yogurt are two other products formed when microorganisms act on a natural product, in this case milk", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " dioxide) of freshly-baked bread. Cheese and yogurt are two other products formed when microorganisms act on a natural product, in this case milk"}}]}, "properties": [], "parentId": "711", "childIds": [], "backendDOMNodeId": 1706}, {"nodeId": "1390", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "711", "childIds": ["2392"], "backendDOMNodeId": 1707, "browsergym_id": "fd4f6c69-ce79-4528"}, {"nodeId": "1391", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "changing its color, odor, texture, and taste.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "changing its color, odor, texture, and taste."}}]}, "properties": [], "parentId": "711", "childIds": [], "backendDOMNodeId": 1716}, {"nodeId": "1392", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Biotechnology has long been used in a variety of industrial processes also. 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Indeed, there is hardly a fruit or vegetable in our diet today that has not been altered by long decades of hybridization.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "7.6-cm) vegetable known as maize has evolved over the years into the 12-in (30-cm), robust product called corn. Indeed, there is hardly a fruit or vegetable in our diet today that has not been altered by long decades of hybridization."}}]}, "properties": [], "parentId": "714", "childIds": [], "backendDOMNodeId": 1758}, {"nodeId": "1409", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Until the late nineteenth century, hybridization was largely a trial-and-error process. Then the work of Gregor Mendel started to become known. 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A farmer must make significant financial investments in seed, "}}]}, "properties": [], "parentId": "717", "childIds": [], "backendDOMNodeId": 1767}, {"nodeId": "1414", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "717", "childIds": ["2401"], "backendDOMNodeId": 1768, "browsergym_id": "2c12ac18-a52f-4963"}, {"nodeId": "1415", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " (fertilizers and pesticides), and machinery to make use of new farming techniques. In developing countries, peasants do not have and cannot borrow the necessary capital. The seed, chemicals, machinery, and oil to operate the equipment must commonly be imported, adding to already crippling foreign debts. In addition, the new techniques often have harmful effects on the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " (fertilizers and pesticides), and machinery to make use of new farming techniques. In developing countries, peasants do not have and cannot borrow the necessary capital. The seed, chemicals, machinery, and oil to operate the equipment must commonly be imported, adding to already crippling foreign debts. In addition, the new techniques often have harmful effects on the "}}]}, "properties": [], "parentId": "717", "childIds": [], "backendDOMNodeId": 1770}, {"nodeId": "1416", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "717", "childIds": ["2402"], "backendDOMNodeId": 1771, "browsergym_id": "536e7790-d11b-41b9"}, {"nodeId": "1417", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " . In spite of problems such as these, however, the green revolution has clearly made an important contribution to the lessening of world hunger.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " . In spite of problems such as these, however, the green revolution has clearly made an important contribution to the lessening of world hunger."}}]}, "properties": [], "parentId": "717", "childIds": [], "backendDOMNodeId": 1773}, {"nodeId": "1418", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Modern methods of hybridization have application in many fields besides agriculture. For example, scientists are now using controlled breeding techniques and other methods from biotechnology to insure the survival of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Modern methods of hybridization have application in many fields besides agriculture. For example, scientists are now using controlled breeding techniques and other methods from biotechnology to insure the survival of "}}]}, "properties": [], "parentId": "718", "childIds": [], "backendDOMNodeId": 1775}, {"nodeId": "1419", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "718", "childIds": ["2403"], "backendDOMNodeId": 1776, "browsergym_id": "aa78c367-d543-49fa"}, {"nodeId": "1420", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " that are threatened or endangered.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " that are threatened or endangered."}}]}, "properties": [], "parentId": "718", "childIds": [], "backendDOMNodeId": 1778}, {"nodeId": "1421", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The nature of biotechnology has undergone a dramatic change in the last half century. That change has come about with the discovery of the role of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The nature of biotechnology has undergone a dramatic change in the last half century. That change has come about with the discovery of the role of "}}]}, "properties": [], "parentId": "719", "childIds": [], "backendDOMNodeId": 1780}, {"nodeId": "1422", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "719", "childIds": ["2404"], "backendDOMNodeId": 1781, "browsergym_id": "f316dcd5-69db-4bec"}, {"nodeId": "1423", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " DNA in living organisms. DNA is a complex molecule that occurs in many different forms. The many forms that DNA can take allow it to store a large amount of information. That information provides cells with the direction they need to carry out all the functions they have to perform in a living organism. It also provides a mechanism by which that information is transmitted efficiently from one generation to the next.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " DNA in living organisms. DNA is a complex molecule that occurs in many different forms. The many forms that DNA can take allow it to store a large amount of information. That information provides cells with the direction they need to carry out all the functions they have to perform in a living organism. It also provides a mechanism by which that information is transmitted efficiently from one generation to the next."}}]}, "properties": [], "parentId": "719", "childIds": [], "backendDOMNodeId": 1783}, {"nodeId": "1424", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "As scientists learned more about the structure of the DNA molecule, they discovered precisely and in chemical terms how genetic information is stored and transmitted. With that knowledge, they have also developed the ability to modify DNA, creating new instructions that direct cells to perform new and unusual functions. 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Since "}}]}, "properties": [], "parentId": "720", "childIds": [], "backendDOMNodeId": 1789}, {"nodeId": "1427", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "genetic engineering", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "genetic engineering"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "720", "childIds": ["2406"], "backendDOMNodeId": 1790, "browsergym_id": "49c2240d-c6d4-4220"}, {"nodeId": "1428", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " normally involves combining two different DNA molecules, it is also referred to as recombinant DNA research.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " normally involves combining two different DNA molecules, it is also referred to as recombinant DNA research."}}]}, "properties": [], "parentId": "720", "childIds": [], "backendDOMNodeId": 1792}, {"nodeId": "1429", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "There is little doubt that genetic engineering is the best known form of biotechnology today. Indeed, it is easy to confuse the two terms and to speak of one when it is the other that is meant. However, the two terms are different in the respect that genetic engineering is only one type of biotechnology.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "There is little doubt that genetic engineering is the best known form of biotechnology today. Indeed, it is easy to confuse the two terms and to speak of one when it is the other that is meant. However, the two terms are different in the respect that genetic engineering is only one type of biotechnology."}}]}, "properties": [], "parentId": "721", "childIds": [], "backendDOMNodeId": 1794}, {"nodeId": "1430", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In theory, the steps involved in genetic engineering are relatively simple. First, scientists decide what kind of changes they want to make in a specific DNA molecule. They might, in some cases, want to alter a human DNA molecule to correct some error that results in a disease such as diabetes. In other cases, a researcher might want to add instructions to a DNA molecule that it does not normally carry. He or she might, for example, want to include instructions for the manufacture of a chemical such as insulin in the DNA of bacteria that normally lack the ability to make insulin.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In theory, the steps involved in genetic engineering are relatively simple. First, scientists decide what kind of changes they want to make in a specific DNA molecule. They might, in some cases, want to alter a human DNA molecule to correct some error that results in a disease such as diabetes. In other cases, a researcher might want to add instructions to a DNA molecule that it does not normally carry. He or she might, for example, want to include instructions for the manufacture of a chemical such as insulin in the DNA of bacteria that normally lack the ability to make insulin."}}]}, "properties": [], "parentId": "722", "childIds": [], "backendDOMNodeId": 1796}, {"nodeId": "1431", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Second, scientists find a way to modify existing DNA to correct errors or add new information. Such methods are now well developed. In one approach, enzymes that \"recognize\" certain specific parts of a DNA molecule are used to cut open the molecule and then insert the new portion.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Second, scientists find a way to modify existing DNA to correct errors or add new information. Such methods are now well developed. In one approach, enzymes that \"recognize\" certain specific parts of a DNA molecule are used to cut open the molecule and then insert the new portion."}}]}, "properties": [], "parentId": "723", "childIds": [], "backendDOMNodeId": 1798}, {"nodeId": "1432", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Third, scientists look for a way to insert the \"correct\" DNA molecule into the organisms in which it is to function. Once inside the organism, the new DNA molecule may give correct instructions to cells in humans (to avoid genetic disorders), in bacteria (resulting in the production of new chemicals), or in other types of cells for other purposes.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Third, scientists look for a way to insert the \"correct\" DNA molecule into the organisms in which it is to function. Once inside the organism, the new DNA molecule may give correct instructions to cells in humans (to avoid genetic disorders), in bacteria (resulting in the production of new chemicals), or in other types of cells for other purposes."}}]}, "properties": [], "parentId": "724", "childIds": [], "backendDOMNodeId": 1800}, {"nodeId": "1433", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Accomplishing these steps in practice is not always easy. One major problem is to get an altered DNA molecule to express itself in the new host cells. That the molecule is able to enter a cell does not mean that it will begin to operate and function (express itself) as scientists hope and plan. This means that many of the expectations held for genetic engineering may not be realized for many years.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Accomplishing these steps in practice is not always easy. One major problem is to get an altered DNA molecule to express itself in the new host cells. That the molecule is able to enter a cell does not mean that it will begin to operate and function (express itself) as scientists hope and plan. This means that many of the expectations held for genetic engineering may not be realized for many years."}}]}, "properties": [], "parentId": "725", "childIds": [], "backendDOMNodeId": 1802}, {"nodeId": "1434", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In spite of problems, genetic engineering has already resulted in a number of impressive accomplishments. Dozens of products that were once available only from natural sources and in limited amounts are now manufactured in abundance by genetically engineered microorganisms at relatively low cost. Insulin, human ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In spite of problems, genetic engineering has already resulted in a number of impressive accomplishments. Dozens of products that were once available only from natural sources and in limited amounts are now manufactured in abundance by genetically engineered microorganisms at relatively low cost. 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In addition, the first trials with the alteration of human DNA to cure a genetic disorder were begun in 1991.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", tissue plasminogen activator, and alpha interferon are examples. In addition, the first trials with the alteration of human DNA to cure a genetic disorder were begun in 1991."}}]}, "properties": [], "parentId": "726", "childIds": [], "backendDOMNodeId": 1807}, {"nodeId": "1437", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The prospects offered by genetic engineering have not been greeted with unanimous enthusiasm by everyone. Many people believe that the hope of curing or avoiding genetic disorders is a positive advance. But they question the wisdom of making genetic changes that are not related to life-threatening disorders. 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The discovery of monoclonal antibodies is an example. Monoclonal antibodies are cells formed by the combination of tumor cells with animal cells that make one and only one kind of antibody. When these two kinds of cells are fused, they result in a cell that reproduces almost infinitely and that recognizes one and only one kind of antigen. Such cells are extremely valuable in a vast array of medical, biological, and industrial applications, including the diagnosis and treatment of disease, the separation and purification of proteins, and the monitoring of pregnancy.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "As progress in genetic engineering goes forward, so do other forms of biotechnology. The discovery of monoclonal antibodies is an example. Monoclonal antibodies are cells formed by the combination of tumor cells with animal cells that make one and only one kind of antibody. When these two kinds of cells are fused, they result in a cell that reproduces almost infinitely and that recognizes one and only one kind of antigen. 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Today, biotechnology refers to a broad range of technologies from ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The word biotechnology was coined in 1919 by Karl Ereky to apply to the interaction of biology with human technology. 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More precisely, biotechnology is defined as the integrated use of biochemistry, microbiology, and engineering sciences in order to achieve technological (industrial) application of the capabilities of microorganisms, cultured tissue cells, and their components.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " (recombinant DNA techniques) to animal breeding and industrial fermentation. More precisely, biotechnology is defined as the integrated use of biochemistry, microbiology, and engineering sciences in order to achieve technological (industrial) application of the capabilities of microorganisms, cultured tissue cells, and their components."}}]}, "properties": [], "parentId": "748", "childIds": [], "backendDOMNodeId": 2085}, {"nodeId": "1493", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Biotechnology has a long history. 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Organisms from bacteria to cows are being genetically modified to produce products that include pharmaceuticals and foods. New, biotechnology-grounded methods of disease gene isolation, analysis, and detection, as well as ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". Organisms from bacteria to cows are being genetically modified to produce products that include pharmaceuticals and foods. 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Thirteen years later, "}}]}, "properties": [], "parentId": "751", "childIds": [], "backendDOMNodeId": 2116}, {"nodeId": "1506", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "James Watson", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "James Watson"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "751", "childIds": ["2443"], "backendDOMNodeId": 2117, "browsergym_id": "0b418513-5cc3-4beb"}, {"nodeId": "1507", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and Francis Crick (1928", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and Francis Crick (1928"}}]}, "properties": [], "parentId": "751", "childIds": [], "backendDOMNodeId": 2119}, {"nodeId": "1508", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "751", "childIds": ["2444"], "backendDOMNodeId": 2120, "browsergym_id": "87342be3-c14b-405d"}, {"nodeId": "1509", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and 1916", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and 1916"}}]}, "properties": [], "parentId": "751", "childIds": [], "backendDOMNodeId": 2127}, {"nodeId": "1510", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "751", "childIds": ["2445"], "backendDOMNodeId": 2128, "browsergym_id": "1a57f652-5137-46d8"}, {"nodeId": "1511", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "2004) described the double helix structure of DNA, a feat that earned them a ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "2004) described the double helix structure of DNA, a feat that earned them a "}}]}, "properties": [], "parentId": "751", "childIds": [], "backendDOMNodeId": 2135}, {"nodeId": "1512", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Nobel Prize", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Nobel Prize"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "751", "childIds": ["2446"], "backendDOMNodeId": 2136, "browsergym_id": "c6f59668-02ba-490a"}, {"nodeId": "1513", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " just a few years later. The modern age of biotechnology began in 1973, when Stanley Cohen (1922", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " just a few years later. The modern age of biotechnology began in 1973, when Stanley Cohen (1922"}}]}, "properties": [], "parentId": "751", "childIds": [], "backendDOMNodeId": 2138}, {"nodeId": "1514", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "751", "childIds": ["2447"], "backendDOMNodeId": 2139, "browsergym_id": "7a94b34e-637d-4ed1"}, {"nodeId": "1515", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ") and Herbert Boyer (1936", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ") and Herbert Boyer (1936"}}]}, "properties": [], "parentId": "751", "childIds": [], "backendDOMNodeId": 2146}, {"nodeId": "1516", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "751", "childIds": ["2448"], "backendDOMNodeId": 2147, "browsergym_id": "fdfb32bc-0dae-44b0"}, {"nodeId": "1517", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ") devised recombinant DNA technology; the deliberate introduction of DNA from one species into another. Their work made possible feats such as the production of human insulin by the bacterium ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ") devised recombinant DNA technology; the deliberate introduction of DNA from one species into another. 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First, scientists decide the changes to be made in a specific DNA molecule. It is desirable in some cases to alter a human DNA molecule to correct errors that result in a disease such as diabetes. In other cases, researchers might add instructions to a DNA molecule that it does not normally carry: instructions for the manufacture of a chemical such as insulin, for example, in the DNA of bacteria that normally lack the ability to make insulin. Scientists also modify existing DNA to correct errors or add new information. Such methods are now well developed. Finally, scientists look for a way to put the recombinant DNA molecule into the organisms in which it is to function. Once inside the organism, the new DNA molecule give correct instructions to cells in humans to correct genetic disorders, in bacteria (resulting in the production of new chemicals), or in other types of cells for other purposes.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In theory, the steps involved in genetic engineering are relatively simple. First, scientists decide the changes to be made in a specific DNA molecule. It is desirable in some cases to alter a human DNA molecule to correct errors that result in a disease such as diabetes. In other cases, researchers might add instructions to a DNA molecule that it does not normally carry: instructions for the manufacture of a chemical such as insulin, for example, in the DNA of bacteria that normally lack the ability to make insulin. Scientists also modify existing DNA to correct errors or add new information. Such methods are now well developed. Finally, scientists look for a way to put the recombinant DNA molecule into the organisms in which it is to function. Once inside the organism, the new DNA molecule give correct instructions to cells in humans to correct genetic disorders, in bacteria (resulting in the production of new chemicals), or in other types of cells for other purposes."}}]}, "properties": [], "parentId": "752", "childIds": [], "backendDOMNodeId": 2164}, {"nodeId": "1523", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Molecular geneticists use molecular cloning techniques to replicate various genetic materials such as gene segments and cells. The process of molecular cloning involves isolating a DNA sequence of interest and obtaining multiple copies of it in an organism that is capable of growth over extended periods. Large quantities of the DNA molecule can then be isolated in pure form for detailed molecular analysis. The now-routine ability to generate virtually endless copies (clones) of a particular sequence is the basis of recombinant DNA technology and its application to human and medical genetics.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Molecular geneticists use molecular cloning techniques to replicate various genetic materials such as gene segments and cells. The process of molecular cloning involves isolating a DNA sequence of interest and obtaining multiple copies of it in an organism that is capable of growth over extended periods. Large quantities of the DNA molecule can then be isolated in pure form for detailed molecular analysis. The now-routine ability to generate virtually endless copies (clones) of a particular sequence is the basis of recombinant DNA technology and its application to human and medical genetics."}}]}, "properties": [], "parentId": "753", "childIds": [], "backendDOMNodeId": 2166}, {"nodeId": "1524", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "A technique called positional cloning is used to map the location of a human disease gene. Positional cloning is a relatively new approach to finding genes. A particular DNA marker is linked to the disease if, in general, family members with certain nucleotides at the marker always have the disease, and family members with other nucleotides at the marker do not have the disease. Once a suspected linkage result is confirmed, researchers can then test other markers known to map close to the one found, in an attempt to move closer and closer to the disease gene of interest. The gene can then be cloned if the DNA sequence has the characteristics of a gene and it can be shown that particular mutations in the gene confer disease.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "A technique called positional cloning is used to map the location of a human disease gene. Positional cloning is a relatively new approach to finding genes. A particular DNA marker is linked to the disease if, in general, family members with certain nucleotides at the marker always have the disease, and family members with other nucleotides at the marker do not have the disease. Once a suspected linkage result is confirmed, researchers can then test other markers known to map close to the one found, in an attempt to move closer and closer to the disease gene of interest. The gene can then be cloned if the DNA sequence has the characteristics of a gene and it can be shown that particular mutations in the gene confer disease."}}]}, "properties": [], "parentId": "754", "childIds": [], "backendDOMNodeId": 2168}, {"nodeId": "1525", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Differences between the organization of the genetic material of organisms like bacteria and ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Differences between the organization of the genetic material of organisms like bacteria and "}}]}, "properties": [], "parentId": "755", "childIds": [], "backendDOMNodeId": 2170}, {"nodeId": "1526", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "755", "childIds": ["2452"], "backendDOMNodeId": 2171, "browsergym_id": "0c5d97f8-3181-438b"}, {"nodeId": "1527", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "higher", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "higher"}}]}, "properties": [], "parentId": "755", "childIds": [], "backendDOMNodeId": 2178}, {"nodeId": "1528", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "755", "childIds": ["2453"], "backendDOMNodeId": 2179, "browsergym_id": "68ddabcc-54fc-49c0"}, {"nodeId": "1529", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " organisms such as humans, and the difference in how the genetic traits coded for by the material are expressed, has complicated the advances in biotechnology. But, increasingly, such species differences are being understood.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " organisms such as humans, and the difference in how the genetic traits coded for by the material are expressed, has complicated the advances in biotechnology. But, increasingly, such species differences are being understood."}}]}, "properties": [], "parentId": "755", "childIds": [], "backendDOMNodeId": 2186}, {"nodeId": "1530", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Genetic engineering has resulted in a number of impressive accomplishments. Dozens of products that were once available only from natural sources and in limited amounts are now manufactured in abundance by genetically engineered microorganisms at relatively low cost. Insulin, human ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Genetic engineering has resulted in a number of impressive accomplishments. Dozens of products that were once available only from natural sources and in limited amounts are now manufactured in abundance by genetically engineered microorganisms at relatively low cost. Insulin, human "}}]}, "properties": [], "parentId": "756", "childIds": [], "backendDOMNodeId": 2188}, {"nodeId": "1531", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "growth hormone", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "growth hormone"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "756", "childIds": ["2454"], "backendDOMNodeId": 2189, "browsergym_id": "6ead84e9-80f4-4873"}, {"nodeId": "1532", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", tissue plasminogen activator, and alpha interferon are examples. In addition, the first trials with the alteration of human DNA to cure a genetic disorder began in 1991.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", tissue plasminogen activator, and alpha interferon are examples. In addition, the first trials with the alteration of human DNA to cure a genetic disorder began in 1991."}}]}, "properties": [], "parentId": "756", "childIds": [], "backendDOMNodeId": 2191}, {"nodeId": "1533", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Commercial applications of biotechnology are numerous. For example, foods are being genetically altered to engineer in more nutritional compounds. The nutraceutical industry is growing to become a potent economic force, generating billions of dollars in sales each year in the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Commercial applications of biotechnology are numerous. For example, foods are being genetically altered to engineer in more nutritional compounds. The nutraceutical industry is growing to become a potent economic force, generating billions of dollars in sales each year in the "}}]}, "properties": [], "parentId": "757", "childIds": [], "backendDOMNodeId": 2193}, {"nodeId": "1534", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "United States", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "United States"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "757", "childIds": ["2455"], "backendDOMNodeId": 2194, "browsergym_id": "7609ce5c-f61c-4750"}, {"nodeId": "1535", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " alone. Genetic manipulation can also help preserve foods longer, allowing a fresher product to reach the supermarket shelves.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " alone. Genetic manipulation can also help preserve foods longer, allowing a fresher product to reach the supermarket shelves."}}]}, "properties": [], "parentId": "757", "childIds": [], "backendDOMNodeId": 2196}, {"nodeId": "1536", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "An aspect of biotechnology that has garnered much attention since the 1990s is cloning. Until 1997, a fully developed organism could not be cloned. 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The procedure that produced Dolly the sheep was reported in the March 6, 1997 edition of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". The procedure that produced Dolly the sheep was reported in the March 6, 1997 edition of "}}]}, "properties": [], "parentId": "758", "childIds": [], "backendDOMNodeId": 2204}, {"nodeId": "1541", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "758", "childIds": ["2458"], "backendDOMNodeId": 2205, "browsergym_id": "17879cab-6809-45bd"}, {"nodeId": "1542", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "While embryo cloning is still a hit or miss procedure, the consensus among researchers involved in embryo cloning is that cloning animal embryos will be perfected. The resulting ease of genetic tailoring could produce higher yielding and disease-resistant livestock.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "While embryo cloning is still a hit or miss procedure, the consensus among researchers involved in embryo cloning is that cloning animal embryos will be perfected. The resulting ease of genetic tailoring could produce higher yielding and disease-resistant livestock."}}]}, "properties": [], "parentId": "759", "childIds": [], "backendDOMNodeId": 2208}, {"nodeId": "1543", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Cloning embryos is similar to what happens naturally when identical twins are created in the womb. All human embryos begin as a single cell. Normally, millions of rounds of division and the formation", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Cloning embryos is similar to what happens naturally when identical twins are created in the womb. All human embryos begin as a single cell. 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With identical twins, as the cell divides it separates into two separate, individual cells. The two separate, individual cells then divide and differentiate independently. The result is two embryos that are identical in the composition of their genetic material.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "of cells that differ in structure and function from other cells gives rise to a human. With identical twins, as the cell divides it separates into two separate, individual cells. The two separate, individual cells then divide and differentiate independently. The result is two embryos that are identical in the composition of their genetic material."}}]}, "properties": [], "parentId": "764", "childIds": [], "backendDOMNodeId": 2238}, {"nodeId": "1550", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In embryo cloning, a cell is mechanically encouraged to divide into two separate, individual cells. These grow and develop separately, creating identical twins. There is continuing debate around the moral and ethical limits on cloning human embryos. As of 2006, it is illegal to use federal research funds in the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In embryo cloning, a cell is mechanically encouraged to divide into two separate, individual cells. These grow and develop separately, creating identical twins. There is continuing debate around the moral and ethical limits on cloning human embryos. 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In November of 2001, the human cloning debate was raised from a theoretical discussion to a concrete discussion. Then, a company in suburban Boston announced that a human cell had been cloned to provide stem cells for research. While the experiment was carried on for only a few cell divisions, the technology required to develop a cloned human being may be almost in place. Indeed, early in 2006 the same company announced its success in establishing cloned human cells that were capable of at least a few cell divisions.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " to clone human embryos. In November of 2001, the human cloning debate was raised from a theoretical discussion to a concrete discussion. Then, a company in suburban Boston announced that a human cell had been cloned to provide stem cells for research. While the experiment was carried on for only a few cell divisions, the technology required to develop a cloned human being may be almost in place. Indeed, early in 2006 the same company announced its success in establishing cloned human cells that were capable of at least a few cell divisions."}}]}, "properties": [], "parentId": "765", "childIds": [], "backendDOMNodeId": 2243}, {"nodeId": "1553", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The prospects offered by biotechnology have not been greeted with unanimous enthusiasm by everyone. Many scientists and laypersons assert that the hope of curing or avoiding genetic disorders through biotechnology is a positive advance. Some hold that the genetically derived nutritional enhancement of foods, such as the nutritional supplementation of rice grown in developing countries, is a worthy aim. Others oppose all forms of genetic engineering, or warn of the dangers of having such technology as the commercial property of a few large companies. There are also concerns about genetic privacy, the effects of transgenic organisms on other organisms and the environment, and animal rights.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The prospects offered by biotechnology have not been greeted with unanimous enthusiasm by everyone. Many scientists and laypersons assert that the hope of curing or avoiding genetic disorders through biotechnology is a positive advance. Some hold that the genetically derived nutritional enhancement of foods, such as the nutritional supplementation of rice grown in developing countries, is a worthy aim. Others oppose all forms of genetic engineering, or warn of the dangers of having such technology as the commercial property of a few large companies. 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The principle objections to biotechnology and foods produced using genetic modification are: concern about possible harm to human health (such as allergic responses to a \"foreign gene\"), possible negative impact to the environment, a general unease about the \"unnatural\" status of biotechnology, and religious concerns about modification.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", despite increased consumer knowledge of biotechnology. The principle objections to biotechnology and foods produced using genetic modification are: concern about possible harm to human health (such as allergic responses to a \"foreign gene\"), possible negative impact to the environment, a general unease about the \"unnatural\" status of biotechnology, and religious concerns about modification."}}]}, "properties": [], "parentId": "785", "childIds": [], "backendDOMNodeId": 2563}, {"nodeId": "1649", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Biotechnology in Animals", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology in Animals"}}]}, "properties": [], "parentId": "786", "childIds": [], "backendDOMNodeId": 2565}, {"nodeId": "1650", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The most controversial applications of biotechnology involve the use of animals and the transfer of genes from animals to plants. The first animal-based application of biotechnology was the approval of the use of bacterially produced bovine somatotropin (bST) in dairy cows. Bovine somatotropin, a naturally occurring ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The most controversial applications of biotechnology involve the use of animals and the transfer of genes from animals to plants. The first animal-based application of biotechnology was the approval of the use of bacterially produced bovine somatotropin (bST) in dairy cows. Bovine somatotropin, a naturally occurring "}}]}, "properties": [], "parentId": "787", "childIds": [], "backendDOMNodeId": 2567}, {"nodeId": "1651", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "787", "childIds": ["2514"], "backendDOMNodeId": 2568, "browsergym_id": "1325bf65-7c4f-477b"}, {"nodeId": "1652", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " , increases milk production. This application has not been commercially successful, however, primarily because of its expense. The ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " , increases milk production. This application has not been commercially successful, however, primarily because of its expense. The "}}]}, "properties": [], "parentId": "787", "childIds": [], "backendDOMNodeId": 2570}, {"nodeId": "1653", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "787", "childIds": ["2515"], "backendDOMNodeId": 2571, "browsergym_id": "469c3a3c-f7c4-41ab"}, {"nodeId": "1654", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " of animals is another potential application of biotechnology. Most experts believe that animal applications of biotechnology will occur slowly because of the social and ethical concerns of consumers.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " of animals is another potential application of biotechnology. Most experts believe that animal applications of biotechnology will occur slowly because of the social and ethical concerns of consumers."}}]}, "properties": [], "parentId": "787", "childIds": [], "backendDOMNodeId": 2573}, {"nodeId": "1655", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Concerns about ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Concerns about "}}]}, "properties": [], "parentId": "788", "childIds": [], "backendDOMNodeId": 2575}, {"nodeId": "1656", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Food Production", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Food Production"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "788", "childIds": ["2516"], "backendDOMNodeId": 2576, "browsergym_id": "5ee3ba1e-32f9-41ea"}, {"nodeId": "1657", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Some concerns about the use of biotechnology for food production include possible allergic reactions to the transferred ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Some concerns about the use of biotechnology for food production include possible allergic reactions to the transferred "}}]}, "properties": [], "parentId": "789", "childIds": [], "backendDOMNodeId": 2579}, {"nodeId": "1658", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "789", "childIds": ["2517"], "backendDOMNodeId": 2580, "browsergym_id": "73c9ef5e-5e9f-47e2"}, {"nodeId": "1659", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " . For example, if a gene from ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " . 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As a result, companies in the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " might now also be allergic to soybeans. 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When, in fact, a company attempted to transfer a gene from ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " . When, in fact, a company attempted to transfer a gene from "}}]}, "properties": [], "parentId": "789", "childIds": [], "backendDOMNodeId": 2603}, {"nodeId": "1674", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Brazil nuts", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Brazil nuts"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "789", "childIds": ["2525"], "backendDOMNodeId": 2604, "browsergym_id": "3fc9e099-d34b-4b7c"}, {"nodeId": "1675", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " to soybeans, the company's tests revealed that they had transferred a gene for an allergen, and work on the project was halted. In 2000 a brand of taco shells was discovered to contain a variety of genetically engineered corn that had been approved by the FDA for use in animal feed, but not for human consumption. Although several antibiotechnology groups used this situation as an example of potential allergenicity stemming from the use of biotechnology, in this case the protein produced by the genetically modified gene was not an allergen. This incident also demonstrated the difficulties in keeping track of a genetically modified food that looks identical to the unmodified food. Other concerns about the use of recombinant DNA technology include potential losses of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " to soybeans, the company's tests revealed that they had transferred a gene for an allergen, and work on the project was halted. In 2000 a brand of taco shells was discovered to contain a variety of genetically engineered corn that had been approved by the FDA for use in animal feed, but not for human consumption. Although several antibiotechnology groups used this situation as an example of potential allergenicity stemming from the use of biotechnology, in this case the protein produced by the genetically modified gene was not an allergen. This incident also demonstrated the difficulties in keeping track of a genetically modified food that looks identical to the unmodified food. Other concerns about the use of recombinant DNA technology include potential losses of "}}]}, "properties": [], "parentId": "789", "childIds": [], "backendDOMNodeId": 2606}, {"nodeId": "1676", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "789", "childIds": ["2526"], "backendDOMNodeId": 2607, "browsergym_id": "df176252-93cc-43ef"}, {"nodeId": "1677", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and negative impacts on other aspects of the environment.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and negative impacts on other aspects of the environment."}}]}, "properties": [], "parentId": "789", "childIds": [], "backendDOMNodeId": 2609}, {"nodeId": "1678", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Safety and Labeling", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Safety and Labeling"}}]}, "properties": [], "parentId": "790", "childIds": [], "backendDOMNodeId": 2611}, {"nodeId": "1679", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In the "}}]}, "properties": [], "parentId": "791", "childIds": [], "backendDOMNodeId": 2613}, {"nodeId": "1680", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "United States", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "United States"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "791", "childIds": ["2527"], "backendDOMNodeId": 2614, "browsergym_id": "3e5a8c24-b260-48ac"}, {"nodeId": "1681", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", the FDA has ruled that foods produced though biotechnology require the same approval process as all other food, and that there is no inherent health risk in the use of biotechnology to develop plant food products. Therefore, no label is required simply to identify foods as products of biotechnology. Manufacturers bear the burden of proof for the safety of the food. To assist them with this, the FDA developed a decision-tree approach that allows food processors to anticipate safety concerns and know when to consult the FDA for guidance. The decision tree focuses on ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", the FDA has ruled that foods produced though biotechnology require the same approval process as all other food, and that there is no inherent health risk in the use of biotechnology to develop plant food products. Therefore, no label is required simply to identify foods as products of biotechnology. Manufacturers bear the burden of proof for the safety of the food. To assist them with this, the FDA developed a decision-tree approach that allows food processors to anticipate safety concerns and know when to consult the FDA for guidance. 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"Labeling of genetically modified foods has sparked additional debate. Labels are required on food produced through biotechnology to inform consumers of any potential health or safety risk. For example, a label is required if a potential allergen is introduced into a food product. A label is also required if a food is transformed so that its nutrient content no longer resembles the original food. For example, so-called golden rice has been genetically engineered to have a higher concentration of beta-carotene than regular rice, and thus it must be included on the label. In response to consumer demands, regulators in ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Labeling of genetically modified foods has sparked additional debate. Labels are required on food produced through biotechnology to inform consumers of any potential health or safety risk. For example, a label is required if a potential allergen is introduced into a food product. A label is also required if a food is transformed so that its nutrient content no longer resembles the original food. For example, so-called golden rice has been genetically engineered to have a higher concentration of beta-carotene than regular rice, and thus it must be included on the label. 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Similar but less restrictive laws have been instituted in Japan. In ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " have instituted mandatory labeling laws for all packaged foods and menus containing genetically modified ingredients. Similar but less restrictive laws have been instituted in Japan. In "}}]}, "properties": [], "parentId": "796", "childIds": [], "backendDOMNodeId": 2678}, {"nodeId": "1705", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Canada", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Canada"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "796", "childIds": ["2555"], "backendDOMNodeId": 2679, "browsergym_id": "6ac42033-2049-4d53"}, {"nodeId": "1706", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", the policy on labeling has remained similar to that of the United States.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", the policy on labeling has remained similar to that of the United States."}}]}, "properties": [], "parentId": "796", "childIds": [], "backendDOMNodeId": 2681}, {"nodeId": "1707", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Some consumer advocates maintain that not requiring a label on all genetically modified foods violates consumers' right to make informed food choices, and many producers of certain foods, such as foods containing soy protein, now include the term \"non-GMO\" on the label to indicate that the product does not contain genetically modified ingredients.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Some consumer advocates maintain that not requiring a label on all genetically modified foods violates consumers' right to make informed food choices, and many producers of certain foods, such as foods containing soy protein, now include the term \"non-GMO\" on the label to indicate that the product does not contain genetically modified ingredients."}}]}, "properties": [], "parentId": "797", "childIds": [], "backendDOMNodeId": 2683}, {"nodeId": "1708", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The application of recombinant DNA technology to foods, commonly called biotechnology, may be viewed as an extension of traditional cross-breeding and fermentation techniques. The technology enables scientists to transfer genetic material from one species to another, and may produce food crops and animals that are different than those obtained using traditional techniques. The FDA has established procedures for approval of food products manufactured using recombinant DNA technology that require food producers to demonstrate the safety of their products. The American Dietetic Association, the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The application of recombinant DNA technology to foods, commonly called biotechnology, may be viewed as an extension of traditional cross-breeding and fermentation techniques. The technology enables scientists to transfer genetic material from one species to another, and may produce food crops and animals that are different than those obtained using traditional techniques. 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These organizations and others acknowledge that long-term health and environmental impacts of the technology are not known, and they encourage continual monitoring of potential impacts.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " have each adopted statements that techniques of biotechnology may have the potential to improve the food supply. 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Before recorded history, humans grew selected plants for food and medicines. They bred animals for food, for work, and as pets. The ancient Egyptians learned how to maintain selected yeast cultures, which allowed them to bake and brew with predictable results. These are all examples of biotechnology. In more recent times, however, the term \"biotechnology\" has mainly been applied to specifically industrial processes that involve the use of biological systems. Today many biotechnology companies use processes that make use of genetically engineered microorganisms.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology, broadly defined, refers to the manipulation of biology or a biological product for some human end. Before recorded history, humans grew selected plants for food and medicines. They bred animals for food, for work, and as pets. The ancient Egyptians learned how to maintain selected yeast cultures, which allowed them to bake and brew with predictable results. These are all examples of biotechnology. In more recent times, however, the term \"biotechnology\" has mainly been applied to specifically industrial processes that involve the use of biological systems. Today many biotechnology companies use processes that make use of genetically engineered microorganisms."}}]}, "properties": [], "parentId": "813", "childIds": [], "backendDOMNodeId": 2909}, {"nodeId": "1744", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "A Revolution in Biology", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "A Revolution in Biology"}}]}, "properties": [], "parentId": "814", "childIds": [], "backendDOMNodeId": 2911}, {"nodeId": "1745", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Following 1953, when ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Following 1953, when "}}]}, "properties": [], "parentId": "815", "childIds": [], "backendDOMNodeId": 2913}, {"nodeId": "1746", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Thomas Watson", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Thomas Watson"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "815", "childIds": ["2577"], "backendDOMNodeId": 2914, "browsergym_id": "a714a50c-6b3f-4b6d"}, {"nodeId": "1747", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and Francis Crick published their famous paper on the double helix structure of DNA, a series of independent discoveries were made in chemistry, biochemistry, genetics, and microbiology, which together brought about a revolution in biology and led to the first experiments in ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and Francis Crick published their famous paper on the double helix structure of DNA, a series of independent discoveries were made in chemistry, biochemistry, genetics, and microbiology, which together brought about a revolution in biology and led to the first experiments in "}}]}, "properties": [], "parentId": "815", "childIds": [], "backendDOMNodeId": 2916}, {"nodeId": "1748", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "genetic engineering", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "genetic engineering"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "815", "childIds": ["2578"], "backendDOMNodeId": 2917, "browsergym_id": "eb9c29ef-7a0f-4d36"}, {"nodeId": "1749", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " in 1973. Because of this revolution, scientists learned to modify living microorganisms in a permanent, predictable way. Bacteria have been made to produce medical products, such as hormones, vaccines, and blood factors, that were formerly not available or available only at great expense or in limited amounts. Crop plants have been developed with increased resistance to disease or insect pests, or with greater tolerance to frost or drought. What has made all these things possible is the collection of biochemical and molecular biological techniques for manipulating genes, which are the basic units of biological inheritance. These are the techniques used in ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " in 1973. Because of this revolution, scientists learned to modify living microorganisms in a permanent, predictable way. Bacteria have been made to produce medical products, such as hormones, vaccines, and blood factors, that were formerly not available or available only at great expense or in limited amounts. Crop plants have been developed with increased resistance to disease or insect pests, or with greater tolerance to frost or drought. What has made all these things possible is the collection of biochemical and molecular biological techniques for manipulating genes, which are the basic units of biological inheritance. 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"}}]}, "properties": [], "parentId": "818", "childIds": [], "backendDOMNodeId": 2938}, {"nodeId": "1761", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Vitamin C", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Vitamin C"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "818", "childIds": ["2584"], "backendDOMNodeId": 2939, "browsergym_id": "0f18c547-a803-4dd4"}, {"nodeId": "1762", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " is a prime example. Humans, as well as other primates, guinea pigs, the Indian ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " is a prime example. Humans, as well as other primates, guinea pigs, the Indian "}}]}, "properties": [], "parentId": "818", "childIds": [], "backendDOMNodeId": 2941}, {"nodeId": "1763", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "fruit bat", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "fruit bat"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "818", "childIds": ["2585"], "backendDOMNodeId": 2942, "browsergym_id": "492992ce-8736-4d1c"}, {"nodeId": "1764", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ", several species of fish, and a number of insects, all lack a key enzyme that is required to convert a sugar, glucose, into vitamin C.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", several species of fish, and a number of insects, all lack a key enzyme that is required to convert a sugar, glucose, into vitamin C."}}]}, "properties": [], "parentId": "818", "childIds": [], "backendDOMNodeId": 2944}, {"nodeId": "1765", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "No single bacterial genus or species is known that will carry out all of the reactions needed to synthesize vitamin C, but there are two (", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "No single bacterial genus or species is known that will carry out all of the reactions needed to synthesize vitamin C, but there are two ("}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2946}, {"nodeId": "1766", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "819", "childIds": ["2586"], "backendDOMNodeId": 2947, "browsergym_id": "5536734f-52e6-43e5"}, {"nodeId": "1767", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " species and ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " species and "}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2949}, {"nodeId": "1768", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "819", "childIds": ["2587"], "backendDOMNodeId": 2950, "browsergym_id": "5ef83e5f-53db-4329"}, {"nodeId": "1769", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " genus) that, between them, can perform all but one of the required steps. In 1985 a gene from one of these genus (", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " genus) that, between them, can perform all but one of the required steps. In 1985 a gene from one of these genus ("}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2952}, {"nodeId": "1770", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "819", "childIds": ["2588"], "backendDOMNodeId": 2953, "browsergym_id": "af2b0aac-e99a-4a02"}, {"nodeId": "1771", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " ) was introduced into the second organism (", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " ) was introduced into the second organism ("}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2955}, {"nodeId": "1772", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "819", "childIds": ["2589"], "backendDOMNodeId": 2956, "browsergym_id": "e3be5338-1e3e-4012"}, {"nodeId": "1773", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " ), resulting in a new bacterial form. This engineered organism can be used to produce a ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " ), resulting in a new bacterial form. This engineered organism can be used to produce a "}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2958}, {"nodeId": "1774", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "819", "childIds": ["2590"], "backendDOMNodeId": 2959, "browsergym_id": "17955abb-b292-4e59"}, {"nodeId": "1775", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " to vitamin C that is converted via one chemical reaction into this essential vitamin. The engineering of many other microorganisms is being used to replace complex chemical reactions. For example, ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " to vitamin C that is converted via one chemical reaction into this essential vitamin. The engineering of many other microorganisms is being used to replace complex chemical reactions. For example, "}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2961}, {"nodeId": "1776", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "819", "childIds": ["2591"], "backendDOMNodeId": 2962, "browsergym_id": "bd7f0c07-7575-48a0"}, {"nodeId": "1777", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " , needed for dietary supplements, are produced on a large scale using genetically modified microorganisms, as are antibiotics.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " , needed for dietary supplements, are produced on a large scale using genetically modified microorganisms, as are antibiotics."}}]}, "properties": [], "parentId": "819", "childIds": [], "backendDOMNodeId": 2964}, {"nodeId": "1778", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Laundry Detergents", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Laundry Detergents"}}]}, "properties": [], "parentId": "820", "childIds": [], "backendDOMNodeId": 2966}, {"nodeId": "1779", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Another important class of compounds produced by biotechnology is ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Another important class of compounds produced by biotechnology is "}}]}, "properties": [], "parentId": "821", "childIds": [], "backendDOMNodeId": 2968}, {"nodeId": "1780", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "821", "childIds": ["2592"], "backendDOMNodeId": 2969, "browsergym_id": "5d30f53f-d962-479f"}, {"nodeId": "1781", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " . These protein ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " . These protein "}}]}, "properties": [], "parentId": "821", "childIds": [], "backendDOMNodeId": 2971}, {"nodeId": "1782", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "821", "childIds": ["2593"], "backendDOMNodeId": 2972, "browsergym_id": "76da40a0-6596-415f"}, {"nodeId": "1783", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " are used widely in both medical and industrial research. Proteases, enzymes that break down proteins, are particularly important in detergents, in tanning hides, in food processing, and in the chemical industry. One of the most significant commercial enzymes of this type is subtilisin, which is produced by a bacterium. Because many stains contain proteins, the manufacturers of laundry detergents include subtilisin in their product. Subtilisin is 274 amino acids long, and one of these, the methionine at position 222, lies right beside the active site of the enzyme. This is the site on the enzyme's surface where the substrate is bound, and where the reaction that is catalyzed by the enzyme takes place. In this instance the substrate is a protein in a stain, and the reaction results in the breaking of a peptide bond in the backbone of the protein. Unfortunately, methionine is an ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " are used widely in both medical and industrial research. Proteases, enzymes that break down proteins, are particularly important in detergents, in tanning hides, in food processing, and in the chemical industry. One of the most significant commercial enzymes of this type is subtilisin, which is produced by a bacterium. Because many stains contain proteins, the manufacturers of laundry detergents include subtilisin in their product. Subtilisin is 274 amino acids long, and one of these, the methionine at position 222, lies right beside the active site of the enzyme. This is the site on the enzyme's surface where the substrate is bound, and where the reaction that is catalyzed by the enzyme takes place. In this instance the substrate is a protein in a stain, and the reaction results in the breaking of a peptide bond in the backbone of the protein. Unfortunately, methionine is an "}}]}, "properties": [], "parentId": "821", "childIds": [], "backendDOMNodeId": 2974}, {"nodeId": "1784", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "amino acid", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "amino acid"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "821", "childIds": ["2594"], "backendDOMNodeId": 2975, "browsergym_id": "8ad34d7b-4314-42c7"}, {"nodeId": "1785", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " that is very easily ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " that is very easily "}}]}, "properties": [], "parentId": "821", "childIds": [], "backendDOMNodeId": 2977}, {"nodeId": "1786", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "821", "childIds": ["2595"], "backendDOMNodeId": 2978, "browsergym_id": "6979675f-1162-4c97"}, {"nodeId": "1787", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " , and laundry detergents are often used in conjunction with bleach, which is a strong oxidizing agent. When used with bleach, the methionine in subtilisin is oxidized and the enzyme is inactivated, preventing the subtilisin from doing its work of breaking down the proteins present in food stains, blood stains, and the like.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " , and laundry detergents are often used in conjunction with bleach, which is a strong oxidizing agent. When used with bleach, the methionine in subtilisin is oxidized and the enzyme is inactivated, preventing the subtilisin from doing its work of breaking down the proteins present in food stains, blood stains, and the like."}}]}, "properties": [], "parentId": "821", "childIds": [], "backendDOMNodeId": 2980}, {"nodeId": "1788", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "To overcome this problem, genetic engineering techniques were used to isolate the gene for subtilisin, and the small part of the gene that codes for methionine 222 was replaced by chemically synthesized DNA fragments that coded for other amino acids. The experiment was done in such a way that nineteen new subtilisin genes were produced, and every possible ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "To overcome this problem, genetic engineering techniques were used to isolate the gene for subtilisin, and the small part of the gene that codes for methionine 222 was replaced by chemically synthesized DNA fragments that coded for other amino acids. The experiment was done in such a way that nineteen new subtilisin genes were produced, and every possible "}}]}, "properties": [], "parentId": "822", "childIds": [], "backendDOMNodeId": 2982}, {"nodeId": "1789", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "amino acid", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "amino acid"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "822", "childIds": ["2596"], "backendDOMNodeId": 2983, "browsergym_id": "deb196cf-d324-4e33"}, {"nodeId": "1790", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " was tried at position 222. Some of the altered genes gave rise to inactive versions of the enzyme, but others resulted in fully functional subtilisin. When these subtilisins were tested for their resistance to oxidation, most were found to be very good (except when cysteine replaced methionine: It too is easily oxidized). So now it is possible to use laundry detergent and bleach at the same time and still remove protein-based stains. This type of gene manipulation, which has been called \"protein engineering,\" has already been used for making beneficial changes in other industrial enzymes, and in proteins used for medical purposes.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " was tried at position 222. Some of the altered genes gave rise to inactive versions of the enzyme, but others resulted in fully functional subtilisin. When these subtilisins were tested for their resistance to oxidation, most were found to be very good (except when cysteine replaced methionine: It too is easily oxidized). So now it is possible to use laundry detergent and bleach at the same time and still remove protein-based stains. This type of gene manipulation, which has been called \"protein engineering,\" has already been used for making beneficial changes in other industrial enzymes, and in proteins used for medical purposes."}}]}, "properties": [], "parentId": "822", "childIds": [], "backendDOMNodeId": 2985}, {"nodeId": "1791", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Other Examples", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Other Examples"}}]}, "properties": [], "parentId": "823", "childIds": [], "backendDOMNodeId": 2987}, {"nodeId": "1792", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Biotechnology companies are continuing to produce new products at an impressive rate. Numerous clinical testing procedures for human disorders such as ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology companies are continuing to produce new products at an impressive rate. 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Many of these assays make use of recombinant ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " ), are based on diagnostic testing kits that have been developed by biotechnology companies. 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Not surprisingly, therefore, the term \u2018biotechnology\u2019 is generally considered synonymous with gene splicing and other forms of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " by Watson and Crick in 1953 and the subsequent development of the tools to cleave and resplice genetic material in the early 1970s. 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In practice, however, biotechnology refers to a library of advanced scientific tools for the manipulation of biological organisms, systems, or components for the production of goods or services in all sectors of human activity.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". 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However, in the future, the most significant breakthroughs in human medicine will result from mapping and understanding the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " currently in the pipeline. 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The ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " \u2014 in elucidating the exact sequence of the billions of nucleotides that constitute the estimated 30\u2009000\u201340\u2009000 genes that are the collective blueprint for human beings and are responsible for some 10\u2009000 genetic disorders. The "}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3274}, {"nodeId": "1866", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "Human Genome Project", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "Human Genome Project"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "843", "childIds": ["2636"], "backendDOMNodeId": 3275, "browsergym_id": "9520dc49-bae0-4e61"}, {"nodeId": "1867", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " was launched in 1990 as a 15-year, $3 billion international effort to map and sequence all human genes. Innovations in sequencing technology have ensured that the project moved ahead of schedule. With less than 5% of all human genes identified at the start of the project, it has become increasingly clear that each new gene discovery proffers new drugs for the diagnosis, treatment, and prevention of human disease. These drugs include therapeutic proteins, diagnostics, ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " was launched in 1990 as a 15-year, $3 billion international effort to map and sequence all human genes. Innovations in sequencing technology have ensured that the project moved ahead of schedule. With less than 5% of all human genes identified at the start of the project, it has become increasingly clear that each new gene discovery proffers new drugs for the diagnosis, treatment, and prevention of human disease. 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This sector is finally moving out from under the shadow of the biopharmaceutical community and is now competing in terms of publicity and investor attention. This is because $1 billion is considered an attractive market in the biopharmaceutical industry, whilst global agricultural markets can readily top $10 billion and the total end-use value of food, fibre, and biomass is estimated to be over $1500 billion. The addressable market on which value can be added and costs cut is at least 6\u20137 times that of its pharmaceutical counterpart. Two of the factors that have encouraged biotechnologists to enter the genetically engineered food and plant arena are the desire of consumers for better tasting foods and a preference for products grown using fewer pesticides. Calgene was the first company to market a genetically improved tomato which could be ripened on the vine without softening and thereby result in improved taste and texture. Antisense technology was used to inhibit the enzyme polygalacturonase which degrades pectin in the cell wall. Similarly, laurate Canola is the world's first oilseed crop that has been genetically engineered to modify oil composition. Laurate is the key raw material used in the manufacture of soap, detergent, food, oleochemical, and personal care products. Other examples of transgenic agricultural crops include high stearate and myristate oils, low saturate oils, high solids tomatoes and potatoes, sweet minipeppers, modified lignin in paper pulp trees, pesticide-resistant plants, and biodegradeable plastics.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". This sector is finally moving out from under the shadow of the biopharmaceutical community and is now competing in terms of publicity and investor attention. This is because $1 billion is considered an attractive market in the biopharmaceutical industry, whilst global agricultural markets can readily top $10 billion and the total end-use value of food, fibre, and biomass is estimated to be over $1500 billion. The addressable market on which value can be added and costs cut is at least 6\u20137 times that of its pharmaceutical counterpart. Two of the factors that have encouraged biotechnologists to enter the genetically engineered food and plant arena are the desire of consumers for better tasting foods and a preference for products grown using fewer pesticides. Calgene was the first company to market a genetically improved tomato which could be ripened on the vine without softening and thereby result in improved taste and texture. Antisense technology was used to inhibit the enzyme polygalacturonase which degrades pectin in the cell wall. Similarly, laurate Canola is the world's first oilseed crop that has been genetically engineered to modify oil composition. Laurate is the key raw material used in the manufacture of soap, detergent, food, oleochemical, and personal care products. Other examples of transgenic agricultural crops include high stearate and myristate oils, low saturate oils, high solids tomatoes and potatoes, sweet minipeppers, modified lignin in paper pulp trees, pesticide-resistant plants, and biodegradeable plastics."}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3289}, {"nodeId": "1877", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3290, "browsergym_id": "a8e370de-1b33-45e9"}, {"nodeId": "1878", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3291, "browsergym_id": "b9e2a21d-17d6-4102"}, {"nodeId": "1879", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The early goals in the development of ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The early goals in the development of "}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3292}, {"nodeId": "1880", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "843", "childIds": ["2640"], "backendDOMNodeId": 3293, "browsergym_id": "c307bdf0-e35b-4b3f"}, {"nodeId": "1881", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " were the increase of the meat and of the production characteristics of food animals. However, long research and development timelines and low projected profit margins, especially in developed nations where food is relatively inexpensive, have shifted priorities to the production of protein pharmaceuticals and nutraceuticals in the milk of transgenic animals. Milk has a high natural protein content and is sequestered in a gland where its proteins exert little direct systemic effect. It provides a renewable production system that is capable of complex and specific \u2018post-translational processing\u2019: that is, modifications to the protein that occur after it has been synthesized as a polypeptide (such as conjugation with carbohydrate moieties), which can alter the biological or therapeutic properties of the protein. Such changes cannot easily be accomplished in conventional cell culture systems. As a result, the \u2018biopharming\u2019 focus has shifted to the production of human blood plasma proteins and other therapeutic proteins, in ruminants such as cows, sheep, and goats which are easy to milk.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " were the increase of the meat and of the production characteristics of food animals. However, long research and development timelines and low projected profit margins, especially in developed nations where food is relatively inexpensive, have shifted priorities to the production of protein pharmaceuticals and nutraceuticals in the milk of transgenic animals. Milk has a high natural protein content and is sequestered in a gland where its proteins exert little direct systemic effect. It provides a renewable production system that is capable of complex and specific \u2018post-translational processing\u2019: that is, modifications to the protein that occur after it has been synthesized as a polypeptide (such as conjugation with carbohydrate moieties), which can alter the biological or therapeutic properties of the protein. Such changes cannot easily be accomplished in conventional cell culture systems. As a result, the \u2018biopharming\u2019 focus has shifted to the production of human blood plasma proteins and other therapeutic proteins, in ruminants such as cows, sheep, and goats which are easy to milk."}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3295}, {"nodeId": "1882", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3296, "browsergym_id": "ac47088d-8fdd-41c1"}, {"nodeId": "1883", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3297, "browsergym_id": "535a7e5c-a0be-49ea"}, {"nodeId": "1884", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "843", "childIds": ["2641"], "backendDOMNodeId": 3298, "browsergym_id": "9249432b-9c79-4cf4"}, {"nodeId": "1885", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " are also capable of producing a variety of polymers, adhesives, and compounds for cosmetics and food preparation. Bioactive natural products are found in organisms that reside in areas which stretch from easily accessible intertidal zones to depths in excess of 1000 m. Collaborations between marine chemists, molecular pharmacologists, and cell biologists have yielded an impressive library of potentially useful cancer, viral, antibiotic, anti-inflammatory, cardiovascular, and CNS drugs.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " are also capable of producing a variety of polymers, adhesives, and compounds for cosmetics and food preparation. Bioactive natural products are found in organisms that reside in areas which stretch from easily accessible intertidal zones to depths in excess of 1000 m. Collaborations between marine chemists, molecular pharmacologists, and cell biologists have yielded an impressive library of potentially useful cancer, viral, antibiotic, anti-inflammatory, cardiovascular, and CNS drugs."}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3300}, {"nodeId": "1886", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3301, "browsergym_id": "37cf8007-8437-4ad3"}, {"nodeId": "1887", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3302, "browsergym_id": "ce3e58d9-47d3-4a77"}, {"nodeId": "1888", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The pharmaceutical, agrichemical, and speciality chemical industries are increasingly requiring molecules which have distinct left- or right-handed forms, so-called ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The pharmaceutical, agrichemical, and speciality chemical industries are increasingly requiring molecules which have distinct left- or right-handed forms, so-called "}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3303}, {"nodeId": "1889", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "843", "childIds": ["2642"], "backendDOMNodeId": 3304, "browsergym_id": "07cdeb58-3933-45a1"}, {"nodeId": "1890", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ". Whilst chemical and biological techniques for producing single left- or right-handed forms are developing apace, it is apparent that no single approach is likely to dominate. Suppliers and customers alike must continue to draw upon the entire range of chemical, enzymatic, and whole-organism tools that are available to produce chiral compounds. Unfortunately, only 10% of the 25\u2009000 or so ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". Whilst chemical and biological techniques for producing single left- or right-handed forms are developing apace, it is apparent that no single approach is likely to dominate. Suppliers and customers alike must continue to draw upon the entire range of chemical, enzymatic, and whole-organism tools that are available to produce chiral compounds. Unfortunately, only 10% of the 25\u2009000 or so "}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3306}, {"nodeId": "1891", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "enzymes", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "enzymes"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "843", "childIds": ["2643"], "backendDOMNodeId": 3307, "browsergym_id": "97f465f3-f01c-44cc"}, {"nodeId": "1892", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " found in nature have been identified and characterized, and, of these, only 25 are produced in large quantities. Despite some duplication in activity among enzymes, there is a need to characterize more in order to exploit their unique specificity and activity. However, barriers to enzyme scale-up include product inhibition and a general reluctance on the part of chemists to use water-based reagents in systems which are traditionally non-aqueous. Consequently, enzymes should be made more user-friendly both for bench chemists exploring novel synthetic strategies and for all stages in pharmaceutical scale-up. However, the biologists' toolbox for catalysis is expanding. For decades, there were only two types of catalyst \u2014 metals and enzymes \u2014 but since 1986 two new classes of biocatalyst have emerged along with the enzymes, ribozymes, and catalytic antibodies. These novel biocatalysts are prepared both by classical biochemical and immunological methods and by recombinant and phage display technologies. Whilst there are still many catalysts still to be discovered, such biocatalysts will have to exhibit improved performance, stability, turnover numbers, specificity, and product yields.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " found in nature have been identified and characterized, and, of these, only 25 are produced in large quantities. Despite some duplication in activity among enzymes, there is a need to characterize more in order to exploit their unique specificity and activity. However, barriers to enzyme scale-up include product inhibition and a general reluctance on the part of chemists to use water-based reagents in systems which are traditionally non-aqueous. Consequently, enzymes should be made more user-friendly both for bench chemists exploring novel synthetic strategies and for all stages in pharmaceutical scale-up. However, the biologists' toolbox for catalysis is expanding. For decades, there were only two types of catalyst \u2014 metals and enzymes \u2014 but since 1986 two new classes of biocatalyst have emerged along with the enzymes, ribozymes, and catalytic antibodies. These novel biocatalysts are prepared both by classical biochemical and immunological methods and by recombinant and phage display technologies. Whilst there are still many catalysts still to be discovered, such biocatalysts will have to exhibit improved performance, stability, turnover numbers, specificity, and product yields."}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3309}, {"nodeId": "1893", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3310, "browsergym_id": "ebbd806a-d20e-4270"}, {"nodeId": "1894", "ignored": false, "role": {"type": "internalRole", "value": "LineBreak"}, "chromeRole": {"type": "internalRole", "value": 109}, "name": {"type": "computedString", "value": "\n", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "\n"}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3311, "browsergym_id": "56a47553-0413-43cd"}, {"nodeId": "1895", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Biotechnology is also playing a role in ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology is also playing a role in "}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3312}, {"nodeId": "1896", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "843", "childIds": ["2644"], "backendDOMNodeId": 3313, "browsergym_id": "b7551ece-d49b-498c"}, {"nodeId": "1897", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": ". Nevertheless, various types of chemical manufacturing, metal plating, wood preserving, and petroleum refining industries currently generate hazardous wastes, comprising volatile organics, chlorinated and petroleum hydrocarbons, solvents, and heavy metals. ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". Nevertheless, various types of chemical manufacturing, metal plating, wood preserving, and petroleum refining industries currently generate hazardous wastes, comprising volatile organics, chlorinated and petroleum hydrocarbons, solvents, and heavy metals. 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Methods include ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " with microbial consortia is being investigated as a means of cleaning up hazardous sites. 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In the future, biotechnology will concentrate on the complexity and interrelatedness of biology, with such targets as the human genome project; genetic medicine; gene and cell therapy; tissue engineering; vaccines; factors for transcribing DNA into RNA; signal transduction and the control of gene expression; managing ageing at the level of programmed cell death, and genes that control ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ", largely through the introduction of recombinant DNA technology to the production of biopharmaceuticals. In the future, biotechnology will concentrate on the complexity and interrelatedness of biology, with such targets as the human genome project; genetic medicine; gene and cell therapy; tissue engineering; vaccines; factors for transcribing DNA into RNA; signal transduction and the control of gene expression; managing ageing at the level of programmed cell death, and genes that control "}}]}, "properties": [], "parentId": "843", "childIds": [], "backendDOMNodeId": 3331}, {"nodeId": "1909", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "cell division", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "cell division"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "843", "childIds": ["2649"], "backendDOMNodeId": 3332, "browsergym_id": "65b83807-4b48-444b"}, {"nodeId": "1910", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "; neurobiotechnology; agri-industrial biotechnology; drug delivery; cell adhesion and communication; and novel diagnostics. 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In 1865, Gregor Mendel presented his laws of heredity, which he deduced by the careful observation of the results of breeding different types of pea plants. Although he did not realize it at the time, Mendel was observing the results of the exchange and altered expression of genetic material.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " of Christ. In 1865, Gregor Mendel presented his laws of heredity, which he deduced by the careful observation of the results of breeding different types of pea plants. 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The modern age of biotechnology began in 1973, when Stanley Cohen and Herbert Boyer devised ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " just a few years later. 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This genetically engineered human insulin was, in fact, the first genetically engineered product approved for sale in the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": ". This genetically engineered human insulin was, in fact, the first genetically engineered product approved for sale in the "}}]}, "properties": [], "parentId": "855", "childIds": [], "backendDOMNodeId": 3568}, {"nodeId": "1953", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "United States", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "United States"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "855", "childIds": ["2675"], "backendDOMNodeId": 3569, "browsergym_id": "3450652d-5013-4422"}, {"nodeId": "1954", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " in 1982.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " in 1982."}}]}, "properties": [], "parentId": "855", "childIds": [], "backendDOMNodeId": 3571}, {"nodeId": "1955", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The latter decades of the twentieth century saw an explosion in the experimental and commercial use of biotechnology.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The latter decades of the twentieth century saw an explosion in the experimental and commercial use of biotechnology."}}]}, "properties": [], "parentId": "856", "childIds": [], "backendDOMNodeId": 3573}, {"nodeId": "1956", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The basic concept of biotechnology involves recombination, or the process where genetic material from just about any living ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "The basic concept of biotechnology involves recombination, or the process where genetic material from just about any living "}}]}, "properties": [], "parentId": "857", "childIds": [], "backendDOMNodeId": 3575}, {"nodeId": "1957", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "857", "childIds": ["2676"], "backendDOMNodeId": 3576, "browsergym_id": "0c17255b-a49b-4224"}, {"nodeId": "1958", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " can be isolated, cut up into pieces using special enzymes, and the pieces encouraged to recombine. The recombination can be between genetic material from the same organism, or between genetic material from different organisms. Differences between the organization of the genetic material of organisms like ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " can be isolated, cut up into pieces using special enzymes, and the pieces encouraged to recombine. The recombination can be between genetic material from the same organism, or between genetic material from different organisms. Differences between the organization of the genetic material of organisms like "}}]}, "properties": [], "parentId": "857", "childIds": [], "backendDOMNodeId": 3578}, {"nodeId": "1959", "ignored": false, "role": {"type": "role", "value": "generic"}, "chromeRole": {"type": "internalRole", "value": 88}, "name": {"type": "computedString", "value": "", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "attribute", "attribute": "title"}]}, "properties": [], "parentId": "857", "childIds": ["2677"], "backendDOMNodeId": 3579, "browsergym_id": "874a424d-fa7c-4b0b"}, {"nodeId": "1960", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " and \"higher\" organisms such as humans, and the difference in how the genetic traits coded for by the material are expressed, has complicated the advances in biotechnology. But, increasingly, such species differences are being understood.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " and \"higher\" organisms such as humans, and the difference in how the genetic traits coded for by the material are expressed, has complicated the advances in biotechnology. But, increasingly, such species differences are being understood."}}]}, "properties": [], "parentId": "857", "childIds": [], "backendDOMNodeId": 3581}, {"nodeId": "1961", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Applications of biotechnology are numerous. For example, foods are being genetically altered to engineer in more nutritional compounds. The nutraceutical industry is growing to become a potent economic force, generating billions of dollars in sales each year in the ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Applications of biotechnology are numerous. For example, foods are being genetically altered to engineer in more nutritional compounds. 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Genetic manipulation can also help preserve foods longer, allowing a fresher product to reach the supermarket shelves.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " alone. Genetic manipulation can also help preserve foods longer, allowing a fresher product to reach the supermarket shelves."}}]}, "properties": [], "parentId": "858", "childIds": [], "backendDOMNodeId": 3586}, {"nodeId": "1964", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "An aspect of biotechnology that has garnered much attention since the 1990s is cloning. Until 1997, a fully developed organism could not be cloned. But, in early 1997, the first success at producing live animals by embryo cloning occurred in Edinburgh, Scotland. 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The result is two embryos that are identical in the composition of their genetic material.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " cells. The two separate, individual cells then divide and differentiate independently. The result is two embryos that are identical in the composition of their genetic material."}}]}, "properties": [], "parentId": "861", "childIds": [], "backendDOMNodeId": 3606}, {"nodeId": "1976", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In embryo cloning, a cell is mechanically encouraged to divide into two separate, individual cells. These grow and develop separately, creating identical twins.There is continuing debate around the moral and ethical limits on cloning human embryos. 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However, for scientists to study their structures, the molecules must be \"held in place\" through crystallization. Large, good-quality crystals are valued by structural biologists, but some organic molecules are easier to crystallize than others are. In some cases the resolution of important biological questions awaits the ability to produce adequate crystals for structural analysis.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Researchers are interested in determining the structure of proteins because the twists and folds of these complex molecules provide clues to their specific functions and how they have evolved over time. However, for scientists to study their structures, the molecules must be \"held in place\" through crystallization. Large, good-quality crystals are valued by structural biologists, but some organic molecules are easier to crystallize than others are. 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This is a problem that could be solved if the experiments were done in space."}}]}, "properties": [], "parentId": "896", "childIds": [], "backendDOMNodeId": 3922}, {"nodeId": "2058", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "Technology and Politics", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Technology and Politics"}}]}, "properties": [], "parentId": "897", "childIds": [], "backendDOMNodeId": 3924}, {"nodeId": "2059", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "However, in considering the potential for biotechnology in space, it is important to understand the technological and political context. 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Any perception that coveted research funds are being diverted to space-based programs without adequate justification causes resentment of such programs within the scientific community.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " in laboratories on Earth, generally at significantly lower cost than that associated with space programs. Any perception that coveted research funds are being diverted to space-based programs without adequate justification causes resentment of such programs within the scientific community."}}]}, "properties": [], "parentId": "898", "childIds": [], "backendDOMNodeId": 3929}, {"nodeId": "2062", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "In addition, the difficulties of funding a large, expensive ", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "In addition, the difficulties of funding a large, expensive "}}]}, "properties": [], "parentId": "899", "childIds": [], "backendDOMNodeId": 3931}, {"nodeId": "2063", "ignored": false, "role": {"type": "role", "value": "link"}, "chromeRole": {"type": "internalRole", "value": 110}, "name": {"type": "computedString", "value": "space station", "sources": [{"type": "relatedElement", "attribute": "aria-labelledby"}, {"type": "attribute", "attribute": "aria-label"}, {"type": "contents", "value": {"type": "computedString", "value": "space station"}}, {"type": "attribute", "attribute": "title", "superseded": true}]}, "properties": [{"name": "focusable", "value": {"type": "booleanOrUndefined", "value": true}}], "parentId": "899", "childIds": ["2723"], "backendDOMNodeId": 3932, "browsergym_id": "39eae281-00c3-496a"}, {"nodeId": "2064", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": " over the many years of planning and construction have resulted in numerous changes to the ISS's design, facilities, and staffing. Refrigerator and freezer space, for example, has been reduced, creating a potential problem for biology research. Exacerbating the problem is uncertainty in the schedule on which shuttles will be available to transport specimens. Another change of major concern to scientists contemplating participation in the program is a possible reduction in crew size, at least initially, from the planned complement of ten to a \"skeleton crew\" of only three.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": " over the many years of planning and construction have resulted in numerous changes to the ISS's design, facilities, and staffing. Refrigerator and freezer space, for example, has been reduced, creating a potential problem for biology research. Exacerbating the problem is uncertainty in the schedule on which shuttles will be available to transport specimens. Another change of major concern to scientists contemplating participation in the program is a possible reduction in crew size, at least initially, from the planned complement of ten to a \"skeleton crew\" of only three."}}]}, "properties": [], "parentId": "899", "childIds": [], "backendDOMNodeId": 3934}, {"nodeId": "2065", "ignored": false, "role": {"type": "internalRole", "value": "StaticText"}, "chromeRole": {"type": "internalRole", "value": 158}, "name": {"type": "computedString", "value": "The reduced crew size drastically limits the ability of astronauts to assist with the research, meaning that the experiments that will be flown must require little to no local human intervention. 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These products may be organisms, cells, parts of a cell, or chemicals for use in medicine, biology, or industry.", "sources": [{"type": "contents", "value": {"type": "computedString", "value": "Biotechnology is the application of biological processes in the development of products. 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\ No newline at end of file