"Like Arcadia, we have always challenged tradition and sought to question the established norms in pursuit of improving the system. Our approach has been to bring about progressive advancements in science communication while upholding fundamental principles of transparency, inclusion, and collaboration. One aspect of this endeavor involves leveraging technology, as the publishing industry has predominantly focused on digitizing existing processes rather than exploring innovative alternatives. Despite the absence of print output in many cases, the industry remains entrenched in a print-first mindset. In contrast, PLOS has embraced the potential of digital technologies since its inception, aligning with the vision of its founders. Now, two decades later, we find ourselves in the era of big data, where science can tackle intricate research inquiries in unprecedented ways. However, to fully harness this potential, it is imperative that all supporting data be accessible and published as a standard practice."

PLOS, like Arcadia, challenges tradition and seeks to improve the system. By embracing progressive improvements in science communication and leveraging digital technologies, PLOS emphasizes transparency, inclusion, collaboration, and the publication of supporting data to address complex research questions in the era of big data.