Choosing of Geneformer-predicted targets for wet lab experiments
Hello,
Having reviewed Supplementary Table 12, I'm curious about how you selected the genes (PLN, GSN, ESRRG, and HMGB1) for the wet lab experiment. It seems there are other genes with a greater shift towards the non-failing state. Could you provide some insight into your selection criteria?
Thank you for your question! This repository is meant for questions about the code. Please take the standard approach of emailing the corresponding author to discuss questions about the paper. Additional considerations for selecting genes include whether the gene is expressed in the in vitro disease model and novelty of the target.
Thank you for your prompt response and for clarifying the focus of the repository. In the future, I will make sure to contact the corresponding authors directly to discuss any questions I have about the paper.