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a mobile app to help patients record their symptoms and share information directly with their physicians.

for tools and resources to track their symptoms.

In programs had patient organizations involved in their development, design and implementation.

The Global Access to Medicines (GATM) program provides eligible patients outside of the U.S. with an option to apply for access to our medicines at no cost under certain circumstances.

Critical to our commitment to understanding the patient journey and helping advocate for the principles and issues that matter to them, we work with patient organizations worldwide.

This includes listening and learning to better understand rare diseases, improving patient care and enhancing patient access to innovative therapies.

a rare disease is by being a key influencer of patient organization engagement standards across the industry through ongoing, proactive thought leadership.

• Connected patient organizations to each other to create channels for best practice sharing.

the ways they suggest we best work with their patient communities.

STRATEGY Alexion’s Global Medical Affairs and Health Economics team integrates a suite of experts who help optimize access, health outcomes and patient experiences by engaging various members of the medical community throughout the patient journey to better understand their pain points and value drivers.

This team delivers evidence from clinical trials and important information from real-world settings like rare disease registries and database bank analyses.

Alexion is committed to safely and effectively delivering our transformative medicines to patients and customers.

that protects the patient and meets the requirements and expectations of all of our key stakeholders, including global regulatory agencies, local governments and laws.

plain-language summaries A FOUNDATION OF QUALITY At Alexion, we believe that quality is for everyone, in accordance with our CSR-STAR foundation of ethics and compliance (see Page 46).

Explicitly stated in our Quality Policy, this means that each Alexion employee is accountable for integrating quality into what we do every day through the decisions we make and actions we take.

five tenets of our Quality Policy: meet or exceed the requirements of our patients and our customers.

As patients face increasing challenges in accessing highly specialized treatments, it is imperative that Alexion adapts quickly.

In our Global Medical Affairs team initiated Project Genesis to develop enterprise-wide evidence generation capabilities to support the approval of and reimbursement for therapies.

The team is dedicated to advancing patient safety and complying with global regulatory requirements.

Clinical trials are a critical part of our efforts to develop innovative new therapies for patients with severe and life-threatening rare diseases.

Alexion's clinical trials investigate potential new therapies that may offer hope to people who haven’t yet found an effective or tolerable solution.

See our website for more information on our clinical trials in a wide range of therapeutic areas.

Authorship of protocols, briefing books, investigator brochures, study reports and submission documents.

In country offices to illustrate how bringing a quality mindset into decision-making helps us anticipate and mitigate quality risks.

they have the right tools to emphasize quality in their daily work.

This improved procedure strengthened our existing reporting process and is essential to understanding customer feedback, the performance of our medicines and areas for improvement.

| 32 WE AIM TO ATTRACT TALENT at Alexion that is inspired by our mission and challenged by our work to transform the lives of people affected by rare and devastating diseases.

Together, we are building the most rewarding company to work for, where people produce and enable meaningful and fulfilling work, are valued and feel they belong.

Our people are empowered to make a difference and their diversity of backgrounds and ideas is encouraged and embraced.

OUR EMPLOYEES Breakthrough innovations require purposedriven, high-performing talent.

company helps us contribute to the patient journey, create value for all of our stakeholders and build a competitive advantage.

Equipping and empowering our leaders to take accountability for shaping our environment.

Engaging and empowering team members around the globe in shaping our culture.

We have dedicated “Culture Champions” from various functions and geographies that connect to share best practices for driving culture transformation across the organization.

As an organization, we’re focused on curating the experience of both our employees and patients (see Page 25).

• Foster a sense of belonging and trust by engaging and acting upon employees’ unique insights and experiences.

for leadership and innovation that is aligned to our business strategy.

• Provide up-to-date, intuitive and easily accessible resources enabled by technology.

• Continuously break traditional thinking to better listen to and advocate for employees, so that employees feel fulfilled professionally and personally.

principles, we regularly solicit employee feedback through our annual Culture Survey, focus groups, interviews and one-on-one dialogue.

This ongoing feedback ensures we are in touch with employees and continually improving.

Based on our Culture Survey results, we focused on enhancing our speak-up culture, creating an environment where employees are encouraged to share their ideas and concerns.

including a Net Promoter Score in 2019, a measure of how likely one’s employees are to recommend the company as a great place to work.

is Alexion's new digital platform aiming to further an exceptional employee experience.

ACE provides employees with news, resources and information to make their work lives easier and connect them with colleagues around the world.

from different perspectives, and think about solutions for many barriers we found.

It was great seeing the teams interact with stakeholders ...

Our LEAP initiative is an effort to broaden our employees’ perceptions and capabilities around patient-driven actions, incorporating our Patient and Stakeholder Value (PSv) model from STAR as a foundation (see Page 25).

Throughout Alexion, we’re hosting an immersive experience to deepen our understanding of the patient and stakeholder experiences.

By challenging our assumptions, conducting active listening exercises and engaging patients and other stakeholders, we’re able to translate our observations and data into insights and innovative solutions that can benefit people living with rare diseases.

diversity extends to all ranks within our organization.

Our executive team is majority female and represents multiple ethnicities.

Nominating and Corporate Governance Committee of our Board of Directors instituted a policy stipulating that gender and ethnically diverse candidates must be included in its pool of candidates for any open director positions.

new perspectives and insights that fuel innovation, create value and support an unparalleled employee experience.

Senator Norris participated in a question and answer session, toured Alexion’s packaging and quality control facilities and had lunch with a group of employees.

In June, we hosted Pride @ College Park, featuring seven events celebrating the LGBTQ+ community over seven days.

We are also proud to be the first pharmaceutical company in Ireland to walk in the Dublin Pride Parade.

an initiative that aims to provide equitable access to quality internships for college students of color and from nontraditional backgrounds.

White & Case to host a Diversity Fellow at our Boston headquarters.

& Case’s with experience working with clients, specifically those seeking to create an environment where the diversity of thought and background are not only encouraged, but preferred.

During her fellowship, a law student at University of Pennsylvania attended various legal and interdepartmental meetings and worked alongside our Chief Legal Officer and other members of our legal team.

Based on the pilot’s success, we plan to deliver this program to Alexion managers on a regular basis, enhancing the program as we receive feedback from attendees.

The Leadership Prof ile also provided the framework and structure for a new Enterprise Leadership training launched in 2019.

We piloted the program for all General Managers, Global Medicine Team Leads and Global Program Team Leads.

program – an intensive, experiential learning program that required those leaders to work together on a critical company project.

As part of that effort, we have built instruments for all levels, based on the key behaviors that make up our Leadership Prof ile.

for those pursuing degrees or courses that will benefit their current or future roles at Alexion.

future of the healthcare industry more broadly, depends on developing an extraordinary talent pipeline.

We engage with institutions of higher learning to connect students with firsthand experiences in the biopharmaceutical sector.

University Outreach and Internships – Alexion offers a chance for students to build on their education at one of the fastest-growing biopharmaceutical companies.

We offer handson internship opportunities and strategically partner with universities around the world.

It allows students at all levels to bring new ideas, fresh perspectives and a passion for excellence to Alexion.

Fellowship Programs – Alexion, in collaboration with Massachusetts College of Pharmacy and Health Sciences (MCPHS) University, offers two unique postdoctoral fellowship programs within our Global Medical Affairs group.

Protecting the health and safety of our colleagues and communities where we operate is essential in living our corporate values.

We’ve formalized this commitment in our EHS Policy, which extends to every location and every Alexion worker, including contractors.

This section focuses on occupational health and safety.

We implement our EHS Policy through our global EHS management system that guides our actions and tracks key performance indicators to manage our risks and drive continuous improvement.

Site leaders, in collaboration with global and local EHS teams, are responsible for routinely identifying and having access to applicable health and safety legal requirements and implementing compliance systems consistent with applicable legal requirements and the standards outlined in our EHS policy.

Each Alexion site implements an EHS Incident Management Procedure that complies with our EHS Policy and local regulatory requirements.

All incidents and near misses, regardless of severity, must be reported so they may be investigated and so controls may be put in place to prevent reoccurrence.

Learnings are disseminated throughout the organization to facilitate continuous improvement.

A key component of our EHS management approach is employee involvement.

Open dialogue and communication are encouraged and rewarded regarding EHS performance data, progress toward objectives, hazard and risk information, significant EHS issues and best practices.

Our safety comment program encourages employees to report all potential and actual risks and incidents.

Every safety comment is tracked, investigated and corrected.

Workers are promptly notified when their comment has been received and subsequently addressed.

Employees’ candid feedback is always valued and sites around the world regularly reward workers who provide impactful safety comments with incentives like special parking spots, gift cards and other recognitions.

In second highest honor at the National Irish Safety Organisation (NISO) Safety awards.

The awards recognize how organizations manage health and safety at work.

to employee health and safety, in concert with our speak-up culture.

arise from EHS incidents and encouraging employees to submit comments on safety topics.

Each challenge was modeled after one of the three core elements of a successful health and safety program: Management Leadership, Worker Participation and Finding/Fixing Hazards.

Finding and fixing hazards in the workplace is an ongoing process that helps better identify and control sources of potential injuries or illnesses.

There are a variety of ways to keep the workplace safe, including establishing procedures to collect and review information about known or potential hazards in the workplace, investigating the root cause of those hazards, and prioritizing hazard controls.

Identifying and correcting these hazards proactively ensures that workers go home, after every shift, to their families safe and sound.

Safe + Sound is a year-round campaign to encourage every workplace to have a safety and health program.

This nationwide effort raises awareness of the value of workplace safety and health programs, which can improve businesses’ safety and health performance, save money, and improve competitiveness.

For the latest news and information visit www.osha.gov/safeandsound.

our COMPANY We work together as a team, respecting and empowering team members, and unlocking value for our stakeholders through the inclusion and diversity of people and ideas, collaboration and continuous learning.

Our emphasis on teamwork and solid governance is fundamental to our CSR approach.