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Branches of the trigeminal nerve Open pop-up dialog box Close Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Branches of the trigeminal nerve Open pop-up dialog box Branches of the trigeminal nerve Open pop-up dialog box Open pop-up dialog box Close Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Close Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Close Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Close Close Close Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Trigeminal neuralgia symptoms may include one or more of these patterns: Episodes of severe, shooting or jabbing pain that may feel like an electric shock Spontaneous attacks of pain or attacks triggered by things such as touching the face, chewing, speaking or brushing teeth Attacks of pain lasting from a few seconds to several minutes Pain that occurs with facial spasms Bouts of multiple attacks lasting days, weeks, months or longer — some people have periods when they experience no pain Pain in areas supplied by the trigeminal nerve, including the cheek, jaw, teeth, gums, lips, or less often the eye and forehead Pain affecting one side of the face at a time Pain focused in one spot or spread in a wider pattern Pain rarely occurring at night while sleeping Attacks that become more frequent and intense over time

trigeminal-neuralgia

The signs and symptoms of carcinoid syndrome depend on which chemicals the carcinoid tumor secretes into your bloodstream. The most common signs and symptoms include: Skin flushing. The skin on your face and upper chest feels hot and changes color — ranging from pink to purple. Flushing episodes may last from a few minutes to a few hours or longer. Flushing may happen for no obvious reason, though sometimes it can be triggered by stress, exercise or drinking alcohol. Facial skin lesions. Purplish areas of spiderlike veins may appear on your nose and upper lip. Diarrhea. Frequent, watery stools sometimes accompanied by abdominal cramps may occur in people who have carcinoid syndrome. Difficulty breathing. Asthma-like signs and symptoms, such as wheezing and shortness of breath, may occur at the same time you experience skin flushing. Rapid heartbeat. Periods of a fast heart rate could be a sign of carcinoid syndrome.

carcinoid-syndrome

Signs and symptoms of trichotillomania often include: Repeatedly pulling your hair out, typically from your scalp, eyebrows or eyelashes, but sometimes from other body areas, and sites may vary over time An increasing sense of tension before pulling, or when you try to resist pulling A sense of pleasure or relief after the hair is pulled Noticeable hair loss, such as shortened hair or thinned or bald areas on the scalp or other areas of your body, including sparse or missing eyelashes or eyebrows Preference for specific types of hair, rituals that accompany hair pulling or patterns of hair pulling Biting, chewing or eating pulled-out hair Playing with pulled-out hair or rubbing it across your lips or face Repeatedly trying to stop pulling out your hair or trying to do it less often without success Significant distress or problems at work, school or in social situations related to pulling out your hair Many people who have trichotillomania also pick their skin, bite their nails or chew their lips. Sometimes pulling hairs from pets or dolls or from materials, such as clothes or blankets, may be a sign. Most people with trichotillomania pull hair in private and generally try to hide the disorder from others. For people with trichotillomania, hair pulling can be: Focused. Some people pull their hair intentionally to relieve tension or distress — for example, pulling hair out to get relief from the overwhelming urge to pull hair. Some people may develop elaborate rituals for pulling hair, such as finding just the right hair or biting pulled hairs. Automatic. Some people pull their hair without even realizing they're doing it, such as when they're bored, reading or watching TV. The same person may do both focused and automatic hair pulling, depending on the situation and mood. Certain positions or rituals may trigger hair pulling, such as resting your head on your hand or brushing your hair. Trichotillomania can be related to emotions: Negative emotions. For many people with trichotillomania, hair pulling is a way of dealing with negative or uncomfortable feelings, such as stress, anxiety, tension, boredom, loneliness, fatigue or frustration. Positive feelings. People with trichotillomania often find that pulling out hair feels satisfying and provides a measure of relief. As a result, they continue to pull their hair to maintain these positive feelings. Trichotillomania is a long-term (chronic) disorder. Without treatment, symptoms can vary in severity over time. For example, the hormonal changes of menstruation can worsen symptoms in women. For some people, if not treated, symptoms can come and go for weeks, months or years at a time. Rarely, hair pulling ends within a few years of starting. When to see a doctor If you can't stop pulling out your hair or you feel embarrassed or ashamed by your appearance as a result of your hair pulling, talk to your doctor. Trichotillomania is not just a bad habit, it's a mental health disorder, and it's unlikely to get better without treatment.

trichotillomania

Symptoms of heartburn include: A burning pain in the chest that usually occurs after eating and may occur at night Pain that worsens when lying down or bending over A bitter or acidic taste in the mouth

heartburn

Knee bursitis signs and symptoms vary, depending on which bursa is affected and what's causing the inflammation. In general, the affected portion of your knee might feel warm, tender and swollen when you put pressure on it. You might also feel pain when you move or even at rest. A sharp blow to the knee can cause symptoms to appear rapidly. But most cases of knee bursitis result from friction and irritation of the bursa that occurs in jobs that require a lot of kneeling on hard surfaces — so symptoms usually begin gradually and can worsen over time. When to see a doctor The bursa that lies over your kneecap can sometimes become infected. Call your doctor if you have a fever in addition to pain and swelling in your knee.

knee-bursitis

Signs and symptoms depend on the type of adjustment disorder and can vary from person to person. You experience more stress than would normally be expected in response to a stressful event, and the stress causes significant problems in your life. Adjustment disorders affect how you feel and think about yourself and the world and may also affect your actions or behavior. Some examples include: Feeling sad, hopeless or not enjoying things you used to enjoy Frequent crying Worrying or feeling anxious, nervous, jittery or stressed out Trouble sleeping Lack of appetite Difficulty concentrating Feeling overwhelmed Difficulty functioning in daily activities Withdrawing from social supports Avoiding important things such as going to work or paying bills Suicidal thoughts or behavior Symptoms of an adjustment disorder start within three months of a stressful event and last no longer than 6 months after the end of the stressful event. However, persistent or chronic adjustment disorders can continue for more than 6 months, especially if the stressor is ongoing, such as unemployment. When to see a doctor Usually stressors are temporary, and we learn to cope with them over time. Symptoms of adjustment disorder get better because the stress has eased. But sometimes the stressful event remains a part of your life. Or a new stressful situation comes up, and you face the same emotional struggles all over again. Talk to your doctor if you continue to struggle or if you're having trouble getting through each day. You can get treatment to help you cope better with stressful events and feel better about life again. If you have concerns about your child's adjustment or behavior, talk with your child's pediatrician. Suicidal thoughts or behavior If you have thoughts of hurting yourself or someone else, call 911 or your local emergency number immediately, go to an emergency room, or confide in a trusted relative or friend. Or contact a suicide hotline. In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline, available 24 hours a day, seven days a week. Or use the Lifeline Chat. Services are free and confidential.

adjustment-disorders

The symptoms of obstructive and central sleep apneas overlap, sometimes making it difficult to determine which type you have. The most common symptoms of obstructive and central sleep apneas include: Loud snoring. Episodes in which you stop breathing during sleep — which would be reported by another person. Gasping for air during sleep. Awakening with a dry mouth. Morning headache. Difficulty staying asleep, known as insomnia. Excessive daytime sleepiness, known as hypersomnia. Difficulty paying attention while awake. Irritability.

sleep-apnea

Signs and symptoms of mitral valve prolapse are due to the amount of blood leaking backward through the valve. Mitral valve prolapse symptoms can vary widely from one person to another. Many people with mitral valve prolapse don't have noticeable symptoms. Other people may have mild symptoms that develop gradually. Symptoms of mitral valve prolapse may include: A racing or irregular heartbeat (arrhythmia) Dizziness or lightheadedness Difficulty breathing or shortness of breath, especially during exercise or when lying flat Fatigue

mitral-valve-prolapse

Mittelschmerz pain usually lasts a few minutes to a few hours, but it may continue for as long as a day or two. Pain from mittelschmerz may be: On one side of your lower abdomen Dull and achy, similar to menstrual cramps Sharp and sudden Accompanied by slight vaginal bleeding or discharge Rarely, severe Mittelschmerz pain occurs on the side of the ovary that's releasing an egg (ovulating). The pain may switch sides every other month, or you may feel pain on the same side for several months. Keep track of your menstrual cycle for several months and note when you feel lower abdominal pain. If it occurs midcycle and goes away without treatment, it's most likely mittelschmerz.

mittelschmerz

Heart failure Open pop-up dialog box Close Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Heart failure Open pop-up dialog box Heart failure Open pop-up dialog box Open pop-up dialog box Close Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Close Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Close Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Close Close Close Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. If you have heart failure, your heart can't supply enough blood to meet your body's needs. Symptoms may develop slowly. Sometimes, heart failure symptoms start suddenly. Heart failure symptoms may include: Shortness of breath with activity or when lying down. Fatigue and weakness. Swelling in the legs, ankles and feet. Rapid or irregular heartbeat. Reduced ability to exercise. Wheezing. A cough that doesn't go away or a cough that brings up white or pink mucus with spots of blood. Swelling of the belly area. Very rapid weight gain from fluid buildup. Nausea and lack of appetite. Difficulty concentrating or decreased alertness. Chest pain if heart failure is caused by a heart attack.

heart-failure

Separation anxiety disorder is diagnosed when symptoms are excessive for the developmental age and cause significant distress in daily functioning. Symptoms may include: Recurrent and excessive distress about anticipating or being away from home or loved ones Constant, excessive worry about losing a parent or other loved one to an illness or a disaster Constant worry that something bad will happen, such as being lost or kidnapped, causing separation from parents or other loved ones Refusing to be away from home because of fear of separation Not wanting to be home alone and without a parent or other loved one in the house Reluctance or refusing to sleep away from home without a parent or other loved one nearby Repeated nightmares about separation Frequent complaints of headaches, stomachaches or other symptoms when separation from a parent or other loved one is anticipated Separation anxiety disorder may be associated with panic disorder and panic attacks ― repeated episodes of sudden feelings of intense anxiety and fear or terror that reach a peak within minutes.

separation-anxiety-disorder

Signs and symptoms of oral lichen planus affect the mucous membranes of the mouth. Appearance The lesions may appear as: Lacy, white, raised patches of tissues Red, swollen, tender patches of tissues Open sores Location These lesions may appear on the: Inside of the cheeks, the most common location Gums Tongue Inner tissues of the lips Palate Pain or discomfort The white, lacy patches may not cause discomfort when they appear on the inside of the cheeks. However, symptoms accompanying red, swollen patches and open sores may include: Burning sensation or pain Sensitivity to hot, acidic or spicy foods Bleeding and irritation with tooth brushing Inflammation of the gums (gingivitis) Painful, thickened patches on the tongue Discomfort when speaking, chewing or swallowing Other types of lichen planus If you have oral lichen planus, you may have lichen planus lesions affecting other parts of your body. Skin. Lesions usually appear as purplish, flat-topped bumps that are often itchy. Genitals. Lesions on the female genitalia often cause pain or burning and discomfort with intercourse. The lesions are usually red and eroded and occasionally appear as white areas. Lesions can also occur on male genitalia. Ears. Lichen planus of the ears can lead to hearing loss. Scalp. When skin lesions appear on the scalp, they may cause temporary or permanent hair loss. Nails. Though rare, lichen planus of the toenails or fingernails may result in ridges on the nails, thinning or splitting of nails, and temporary or permanent nail loss. Eyes. Rarely, lichen planus may involve the mucous membrane surfaces of the eyes, and can cause scarring and blindness. Esophagus. Lichen planus of the esophagus is rare, but when it occurs, it may result in a narrowing of the esophagus or the formation of tightened, ringlike bands in the esophagus that can make swallowing difficult.

oral-lichen-planus

Salmonella infection is usually caused by eating raw or undercooked meat, poultry, and eggs or egg products or by drinking unpasteurized milk. The incubation period — the time between exposure and illness — can be 6 hours to 6 days. Often, people who have salmonella infection think they have the stomach flu. Possible signs and symptoms of salmonella infection include: Diarrhea Stomach (abdominal) cramps Fever Nausea Vomiting Chills Headache Blood in the stool Signs and symptoms of salmonella infection generally last a few days to a week. Diarrhea may last up to 10 days, but it may take several months before bowels return to usual stool habits. A few varieties of salmonella bacteria result in typhoid fever, a sometimes deadly disease that is more common in developing countries.

salmonella

Signs and symptoms of diabetes insipidus include: Being extremely thirsty Producing large amounts of pale urine Frequently needing to get up to urinate during the night Preferring cold drinks If your condition is serious and you drink a lot of fluids, you can produce as much as 20 quarts (about 19 liters) of urine a day. A healthy adult typically urinates an average of 1 to 2 quarts (about 1 to 2 liters) a day. An infant or young child with diabetes insipidus may have the following signs and symptoms: Heavy, wet diapers Bed-wetting Trouble sleeping Fever Vomiting Constipation Delayed growth Weight loss

diabetes-insipidus

Signs and symptoms of testicular torsion include: Sudden, severe pain in the scrotum — the loose bag of skin under your penis that contains the testicles Swelling of the scrotum Abdominal pain Nausea and vomiting A testicle that's positioned higher than normal or at an unusual angle Frequent urination Fever Young boys who have testicular torsion typically wake up due to scrotal pain in the middle of the night or early in the morning.

testicular-torsion

Signs and symptoms of rheumatoid arthritis may include: Tender, warm, swollen joints Joint stiffness that is usually worse in the mornings and after inactivity Fatigue, fever and loss of appetite Early rheumatoid arthritis tends to affect your smaller joints first — particularly the joints that attach your fingers to your hands and your toes to your feet. As the disease progresses, symptoms often spread to the wrists, knees, ankles, elbows, hips and shoulders. In most cases, symptoms occur in the same joints on both sides of your body. About 40% of people who have rheumatoid arthritis also experience signs and symptoms that don't involve the joints. Areas that may be affected include: Skin Eyes Lungs Heart Kidneys Salivary glands Nerve tissue Bone marrow Blood vessels Rheumatoid arthritis signs and symptoms may vary in severity and may even come and go. Periods of increased disease activity, called flares, alternate with periods of relative remission — when the swelling and pain fade or disappear. Over time, rheumatoid arthritis can cause joints to deform and shift out of place.

rheumatoid-arthritis

A fibroadenoma is a solid breast lump that often causes no pain. It is: Round with distinct, smooth borders Easily moved Firm or rubbery A fibroadenoma often grows slowly. The average size is about 1 inch (2.5 centimeters). A fibroadenoma can get bigger over time. It may be tender or cause soreness a few days before your period. A large fibroadenoma may hurt when you touch it. But most often, this type of breast lump causes no pain. You can have a single fibroadenoma or more than one fibroadenoma. They can occur in one or both breasts. Some fibroadenomas shrink over time. Most fibroadenomas in adolescents shrink over many months to a few years. They then disappear. Fibroadenomas may also change shape over time. Fibroadenomas may get bigger during pregnancy. They might shrink after menopause.

fibroadenoma

The signs and symptoms of lichen planus vary depending on the areas affected. Typical signs and symptoms are: Purplish, flat bumps, most often on the inner forearm, wrist or ankle, and sometimes the genitals Itching Blisters that break to form scabs or crusts Lacy white patches in the mouth or on the lips or tongue Painful sores in the mouth or vagina Hair loss Change in scalp color Nail damage or loss

lichen-planus

Common anxiety signs and symptoms include: Feeling nervous, restless or tense Having a sense of impending danger, panic or doom Having an increased heart rate Breathing rapidly (hyperventilation) Sweating Trembling Feeling weak or tired Trouble concentrating or thinking about anything other than the present worry Having trouble sleeping Experiencing gastrointestinal (GI) problems Having difficulty controlling worry Having the urge to avoid things that trigger anxiety Several types of anxiety disorders exist: Agoraphobia (ag-uh-ruh-FOE-be-uh) is a type of anxiety disorder in which you fear and often avoid places or situations that might cause you to panic and make you feel trapped, helpless or embarrassed. Anxiety disorder due to a medical condition includes symptoms of intense anxiety or panic that are directly caused by a physical health problem. Generalized anxiety disorder includes persistent and excessive anxiety and worry about activities or events — even ordinary, routine issues. The worry is out of proportion to the actual circumstance, is difficult to control and affects how you feel physically. It often occurs along with other anxiety disorders or depression. Panic disorder involves repeated episodes of sudden feelings of intense anxiety and fear or terror that reach a peak within minutes (panic attacks). You may have feelings of impending doom, shortness of breath, chest pain, or a rapid, fluttering or pounding heart (heart palpitations). These panic attacks may lead to worrying about them happening again or avoiding situations in which they've occurred. Selective mutism is a consistent failure of children to speak in certain situations, such as school, even when they can speak in other situations, such as at home with close family members. This can interfere with school, work and social functioning. Separation anxiety disorder is a childhood disorder characterized by anxiety that's excessive for the child's developmental level and related to separation from parents or others who have parental roles. Social anxiety disorder (social phobia) involves high levels of anxiety, fear and avoidance of social situations due to feelings of embarrassment, self-consciousness and concern about being judged or viewed negatively by others. Specific phobias are characterized by major anxiety when you're exposed to a specific object or situation and a desire to avoid it. Phobias provoke panic attacks in some people. Substance-induced anxiety disorder is characterized by symptoms of intense anxiety or panic that are a direct result of misusing drugs, taking medications, being exposed to a toxic substance or withdrawal from drugs. Other specified anxiety disorder and unspecified anxiety disorder are terms for anxiety or phobias that don't meet the exact criteria for any other anxiety disorders but are significant enough to be distressing and disruptive.

anxiety

In most cases laryngitis symptoms last less than a couple of weeks and are caused by something minor, such as a virus. Less often, laryngitis symptoms are caused by something more serious or long lasting. Laryngitis signs and symptoms can include: Hoarseness Weak voice or voice loss Tickling sensation and rawness in your throat Sore throat Dry throat Dry cough

laryngitis

Drug addiction symptoms or behaviors include, among others: Feeling that you have to use the drug regularly — daily or even several times a day Having intense urges for the drug that block out any other thoughts Over time, needing more of the drug to get the same effect Taking larger amounts of the drug over a longer period of time than you intended Making certain that you maintain a supply of the drug Spending money on the drug, even though you can't afford it Not meeting obligations and work responsibilities, or cutting back on social or recreational activities because of drug use Continuing to use the drug, even though you know it's causing problems in your life or causing you physical or psychological harm Doing things to get the drug that you normally wouldn't do, such as stealing Driving or doing other risky activities when you're under the influence of the drug Spending a good deal of time getting the drug, using the drug or recovering from the effects of the drug Failing in your attempts to stop using the drug Experiencing withdrawal symptoms when you attempt to stop taking the drug Recognizing unhealthy drug use in family members Sometimes it's difficult to distinguish normal teenage moodiness or anxiety from signs of drug use. Possible signs that your teenager or other family member is using drugs include: Problems at school or work — frequently missing school or work, a sudden disinterest in school activities or work, or a drop in grades or work performance Physical health issues — lack of energy and motivation, weight loss or gain, or red eyes Neglected appearance — lack of interest in clothing, grooming or looks Changes in behavior — major efforts to bar family members from entering the teenager's room or being secretive about going out with friends; or drastic changes in behavior and in relationships with family and friends Money issues — sudden requests for money without a reasonable explanation; or your discovery that money is missing or has been stolen or that items have disappeared from your home, indicating maybe they're being sold to support drug use Recognizing signs of drug use or intoxication Signs and symptoms of drug use or intoxication may vary, depending on the type of drug. Below you'll find several examples. Marijuana, hashish and other cannabis-containing substances People use cannabis by smoking, eating or inhaling a vaporized form of the drug. Cannabis often precedes or is used along with other substances, such as alcohol or illegal drugs, and is often the first drug tried. Signs and symptoms of recent use can include: A sense of euphoria or feeling "high" A heightened sense of visual, auditory and taste perception Increased blood pressure and heart rate Red eyes Dry mouth Decreased coordination Difficulty concentrating or remembering Slowed reaction time Anxiety or paranoid thinking Cannabis odor on clothes or yellow fingertips Major cravings for certain foods at unusual times Long-term use is often associated with: Decreased mental sharpness Poor performance at school or at work Ongoing cough and frequent lung infections K2, Spice and bath salts Two groups of synthetic drugs — synthetic cannabinoids and substituted or synthetic cathinones — are illegal in most states. The effects of these drugs can be dangerous and unpredictable, as there is no quality control and some ingredients may not be known. Synthetic cannabinoids, also called K2 or Spice, are sprayed on dried herbs and then smoked, but can be prepared as an herbal tea. A liquid form can be vaporized in electronic cigarettes. Despite manufacturer claims, these are chemical compounds rather than "natural" or harmless products. These drugs can produce a "high" similar to marijuana and have become a popular but dangerous alternative. Signs and symptoms of recent use can include: A sense of euphoria or feeling "high" Elevated mood An altered sense of visual, auditory and taste perception Extreme anxiety or agitation Paranoia Hallucinations Increased heart rate and blood pressure or heart attack Vomiting Confusion Violent behavior Substituted cathinones, also called "bath salts," are mind-altering (psychoactive) substances similar to amphetamines such as ecstasy (MDMA) and cocaine. Packages are often labeled as other products to avoid detection. Despite the name, these are not bath products such as Epsom salts. Substituted cathinones can be eaten, snorted, inhaled or injected and are highly addictive. These drugs can cause severe intoxication, which results in dangerous health effects or even death. Signs and symptoms of recent use can include: Feeling "high" Increased sociability Increased energy and agitation Increased sex drive Increased heart rate and blood pressure Problems thinking clearly Loss of muscle control Paranoia Panic attacks Hallucinations Delirium Psychotic and violent behavior Barbiturates, benzodiazepines and hypnotics Barbiturates, benzodiazepines and hypnotics are prescription central nervous system depressants. They're often used and misused in search for a sense of relaxation or a desire to "switch off" or forget stress-related thoughts or feelings. Barbiturates. An example is phenobarbital. Benzodiazepines. Examples include sedatives, such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), clonazepam (Klonopin) and chlordiazepoxide (Librium). Hypnotics. Examples include prescription sleeping medicines such as zolpidem (Ambien) and zaleplon (Sonata). Signs and symptoms of recent use can include: Drowsiness Slurred speech Lack of coordination Irritability or changes in mood Problems concentrating or thinking clearly Memory problems Involuntary eye movements Lack of inhibition Slowed breathing and reduced blood pressure Falls or accidents Dizziness Meth, cocaine and other stimulants Stimulants include amphetamines, meth (methamphetamine), cocaine, methylphenidate (Ritalin, Concerta, others) and amphetamine-dextroamphetamine (Adderall XR, Mydayis). They're often used and misused in search of a "high," or to boost energy, to improve performance at work or school, or to lose weight or control appetite. Signs and symptoms of recent use can include: Feeling of happy excitement and too much confidence Increased alertness Increased energy and restlessness Behavior changes or aggression Rapid or rambling speech Larger than usual pupils, the black circles in the middle of the eyes Confusion, delusions and hallucinations Irritability, anxiety or paranoia Changes in heart rate, blood pressure and body temperature Nausea or vomiting with weight loss Poor judgment Nasal congestion and damage to the mucous membrane of the nose (if snorting drugs) Mouth sores, gum disease and tooth decay from smoking drugs ("meth mouth") Insomnia Depression as the drug wears off Club drugs Club drugs are commonly used at clubs, concerts and parties. Examples include methylenedioxymethamphetamine, also called MDMA, ecstasy or molly, and gamma-hydroxybutyric acid, known as GHB. Other examples include ketamine and flunitrazepam or Rohypnol ― a brand used outside the U.S. ― also called roofie. These drugs are not all in the same category, but they share some similar effects and dangers, including long-term harmful effects. Because GHB and flunitrazepam can cause sedation, muscle relaxation, confusion and memory loss, the potential for sexual misconduct or sexual assault is associated with the use of these drugs. GHB Signs and symptoms of use of club drugs can include: Hallucinations Paranoia Larger than usual pupils Chills and sweating Involuntary shaking (tremors) Behavior changes Muscle cramping and teeth clenching Muscle relaxation, poor coordination or problems moving Reduced inhibitions Heightened or altered sense of sight, sound and taste Poor judgment Memory problems or loss of memory Reduced consciousness Increased or decreased heart rate and blood pressure Hallucinogens Use of hallucinogens can produce different signs and symptoms, depending on the drug. The most common hallucinogens are lysergic acid diethylamide (LSD) and phencyclidine (PCP). LSD use may cause: LSD Hallucinations Greatly reduced perception of reality, for example, interpreting input from one of your senses as another, such as hearing colors Impulsive behavior Rapid shifts in emotions Permanent mental changes in perception Rapid heart rate and high blood pressure Tremors Flashbacks, a reexperience of the hallucinations — even years later PCP use may cause: PCP A feeling of being separated from your body and surroundings Hallucinations Problems with coordination and movement Aggressive, possibly violent behavior Involuntary eye movements Lack of pain sensation Increase in blood pressure and heart rate Problems with thinking and memory Problems speaking Poor judgment Intolerance to loud noise Sometimes seizures or coma Inhalants Signs and symptoms of inhalant use vary, depending on the substance. Some commonly inhaled substances include glue, paint thinners, correction fluid, felt tip marker fluid, gasoline, cleaning fluids and household aerosol products. Due to the toxic nature of these substances, users may develop brain damage or sudden death. Signs and symptoms of use can include: Possessing an inhalant substance without a reasonable explanation Brief happy excitement Behaving as if drunk Reduced ability to keep impulses under control Aggressive behavior or eagerness to fight Dizziness Nausea or vomiting Involuntary eye movements Appearing under the influence of drugs, with slurred speech, slow movements and poor coordination Irregular heartbeats Tremors Lingering odor of inhalant material Rash around the nose and mouth Opioid painkillers Opioids are narcotic, painkilling drugs produced from opium or made synthetically. This class of drugs includes, among others, heroin, morphine, codeine, methadone, fentanyl and oxycodone. Sometimes called the "opioid epidemic," addiction to opioid prescription pain medicines has reached an alarming rate across the United States. Some people who've been using opioids over a long period of time may need physician-prescribed temporary or long-term drug substitution during treatment. Signs and symptoms of narcotic use and dependence can include: A sense of feeling "high" Reduced sense of pain Agitation, drowsiness or sedation Slurred speech Problems with attention and memory Pupils that are smaller than usual Lack of awareness or inattention to surrounding people and things Problems with coordination Depression Confusion Constipation Runny nose or nose sores (if snorting drugs) Needle marks (if injecting drugs)

drug-addiction

The factor V Leiden mutation does not itself cause any symptoms. Since factor V Leiden is a risk for developing blood clots in the leg or lungs, the first indication that you have the disorder may be the development of an abnormal blood clot. Some clots do no damage and disappear on their own. Others can be life-threatening. Symptoms of a blood clot depend on what part of your body is affected. A clot in a deep vein This is known as deep vein thrombosis (DVT), which most commonly occurs in the legs. A DVT may not cause any symptoms. If signs and symptoms do occur, they can include: Pain Swelling Redness Warmth A clot that travels to your lungs Known as a pulmonary embolism, this occurs when a portion of a DVT breaks free and travels through the right side of your heart to your lung, where it blocks blood flow. This can be a life-threatening situation. Signs and symptoms may include: Sudden shortness of breath Chest pain when breathing in A cough that produces bloody or blood-streaked sputum Rapid heartbeat

factor-v-leiden

Stages of frostbite Open pop-up dialog box Close Stages of frostbite Stages of frostbite Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Stages of frostbite Open pop-up dialog box Stages of frostbite Open pop-up dialog box Open pop-up dialog box Close Stages of frostbite Stages of frostbite Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Close Stages of frostbite Stages of frostbite Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Close Stages of frostbite Stages of frostbite Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Close Close Close Stages of frostbite Stages of frostbite Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Stages of frostbite Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Skin without cold damage (1) has no change in color or texture. Frostnip (2) is mild frostbite that irritates the skin, causing a change in skin color and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin and can be treated with first-aid measures. With superficial frostbite (3), the skin feels warm. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. With deep frostbite (4), you may experience numbness. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies. Frostnip Open pop-up dialog box Close Frostnip Frostnip Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Frostnip Open pop-up dialog box Frostnip Open pop-up dialog box Open pop-up dialog box Close Frostnip Frostnip Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Close Frostnip Frostnip Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Close Frostnip Frostnip Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Close Close Close Frostnip Frostnip Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Frostnip Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Frostnip, a mild form of frostbite, irritates the skin, causing redness and a cold feeling followed by numbness. Frostnip doesn't permanently damage the skin. Signs and symptoms of frostbite include: At first, cold skin and a prickling feeling Numbness Skin that looks red, white, bluish-white, grayish-yellow, purplish, brown or ashen, depending on the severity of the condition and usual skin color Hard or waxy-looking skin Clumsiness due to joint and muscle stiffness Blistering after rewarming, in severe cases Frostbite is most common on the fingers, toes, nose, ears, cheeks and chin. Because of skin numbness, you may not realize you have frostbite until someone points it out. Changes in the color of the affected area might be difficult to see on brown or Black skin. Frostbite occurs in several stages: Frostnip. Frostnip is a mild form of frostbite. Continued cold exposure leads to numbness in the affected area. As your skin warms, you may feel pain and tingling. Frostnip doesn't cause permanent skin damage. Superficial frostbite. Superficial frostbite causes slight changes in skin color. The skin may begin to feel warm — a sign of serious skin involvement. If you treat frostbite with rewarming at this stage, the surface of the skin may appear mottled. And you may notice stinging, burning and swelling. A fluid-filled blister may appear 12 to 36 hours after rewarming the skin. Deep (severe) frostbite. As frostbite progresses, it affects all layers of the skin as well as the tissues that lie below. The skin turns white or blue-gray and you lose all sensation of cold, pain or discomfort in the area. Joints or muscles may stop working. Large blisters form 24 to 48 hours after rewarming. The tissue turns black and hard as it dies.

frostbite

Your lymphatic system is a network of organs, vessels and lymph nodes situated throughout your body. Many lymph nodes are located in your head and neck region. Lymph nodes that frequently swell are in this area, as well as in your armpits and groin area. Swollen lymph nodes are a sign that something is wrong somewhere in your body. When your lymph nodes first swell, you might notice: Tenderness and pain in the lymph nodes Swelling that may be the size of a pea or kidney bean, or even larger in the lymph nodes Depending on the cause of your swollen lymph nodes, other signs and symptoms you might have include: Runny nose, sore throat, fever and other indications of an upper respiratory infection General swelling of lymph nodes throughout your body. When this occurs, it may indicate an infection, such as HIV or mononucleosis, or an immune system disorder, such as lupus or rheumatoid arthritis Hard, fixed, rapidly growing nodes, indicating a possible cancer or lymphoma Fever Night sweats

swollen-lymph-nodes

Heart disease symptoms depend on the type of heart disease. Symptoms of heart disease in the blood vessels Coronary artery disease is a common heart condition that affects the major blood vessels that supply the heart muscle. Cholesterol deposits (plaques) in the heart arteries are usually the cause of coronary artery disease. The buildup of these plaques is called atherosclerosis (ath-ur-o-skluh-ROE-sis). Atherosclerosis reduces blood flow to the heart and other parts of the body. It can lead to a heart attack, chest pain (angina) or stroke. Coronary artery disease symptoms may be different for men and women. For instance, men are more likely to have chest pain. Women are more likely to have other symptoms along with chest discomfort, such as shortness of breath, nausea and extreme fatigue. Symptoms of coronary artery disease can include: Chest pain, chest tightness, chest pressure and chest discomfort (angina) Shortness of breath Pain in the neck, jaw, throat, upper belly area or back Pain, numbness, weakness or coldness in the legs or arms if the blood vessels in those body areas are narrowed You might not be diagnosed with coronary artery disease until you have a heart attack, angina, stroke or heart failure. It's important to watch for heart symptoms and discuss concerns with your health care provider. Heart (cardiovascular) disease can sometimes be found early with regular health checkups. What is coronary artery disease? A Mayo Clinic cardiologist explains. Stephen Kopecky, M.D., talks about the risk factors, symptoms and treatment of coronary artery disease (CAD). Learn how lifestyle changes can lower your risk. What is coronary artery disease? A Mayo Clinic cardiologist explains. Stephen Kopecky, M.D., talks about the risk factors, symptoms and treatment of coronary artery disease (CAD). Learn how lifestyle changes can lower your risk. Show transcript for video What is coronary artery disease? A Mayo Clinic cardiologist explains. {Music playing} Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: I'm Dr. Stephen Kopecky, a cardiologist at Mayo Clinic. In this video, we'll cover the basics of coronary artery disease. What is it? Who gets it? The symptoms, diagnosis and treatment. Whether you're looking for answers for yourself or someone you love, we're here to give you the best information available. Coronary artery disease, also called CAD, is a condition that affects your heart. It is the most common heart disease in the United States. CAD happens when coronary arteries struggle to supply the heart with enough blood, oxygen and nutrients. Cholesterol deposits, or plaques, are almost always to blame. These buildups narrow your arteries, decreasing blood flow to your heart. This can cause chest pain, shortness of breath or even a heart attack. CAD typically takes a long time to develop. So often, patients don't know that they have it until there's a problem. But there are ways to prevent coronary artery disease, and ways to know if you're at risk and ways to treat it. Who gets it? Anyone can develop CAD. It begins when fats, cholesterols and other substances gather along the walls of your arteries. This process is called atherosclerosis. It's typically no cause for concern. However, too much buildup can lead to a blockage, obstructing blood flow. There are a number of risk factors, common red flags, that can contribute to this and ultimately lead to coronary artery disease. First, getting older can mean more damaged and narrowed arteries. Second, men are generally at a greater risk. But the risk for women increases after menopause. Existing health conditions matter, too. High blood pressure can thicken your arteries, narrowing your blood flow. High cholesterol levels can increase the rate of plaque buildup. Diabetes is also associated with higher risk, as is being overweight. Your lifestyle plays a large role as well. Physical inactivity, long periods of unrelieved stress in your life, an unhealthy diet and smoking can all increase your risk. And finally, family history. If a close relative was diagnosed at an early age with heart disease, you're at a greater risk. All these factors together can paint a picture of your risk for developing CAD. What are the symptoms? When coronary arteries become narrow, the heart doesn't get enough oxygen-rich blood. Remember, unlike most pumps, the heart has to pump its own energy supply. It's working harder with less. And you may begin to notice these signs and symptoms of pressure or tightness in your chest. This pain is called angina. It may feel like somebody is standing on your chest. When your heart can't pump enough blood to meet your body's needs, you might develop shortness of breath or extreme fatigue during activities. And if an artery becomes totally blocked, it leads to a heart attack. Classic signs and symptoms of a heart attack include crushing, substernal chest pain, pain in your shoulders or arms, shortness of breath, and sweating. However, many heart attacks have minimal or no symptoms and are found later during routine testing. How is it diagnosed? Diagnosing CAD starts by talking to your doctor. They'll be able to look at your medical history, do a physical exam and order routine blood work. Depending on that, they may suggest one or more of the following tests: an electrocardiogram or ECG, an echocardiogram or soundwave test of the heart, stress test, cardiac catheterization and angiogram, or a cardiac CT scan. How is it treated? Treating coronary artery disease usually means making changes to your lifestyle. This might be eating healthier foods, exercising regularly, losing excess weight, reducing stress or quitting smoking. The good news is these changes can do a lot to improve your outlook. Living a healthier life translates to having healthier arteries. When necessary, treatment could involve drugs like aspirin, cholesterol-modifying medications, beta-blockers, or certain medical procedures like angioplasty or coronary artery bypass surgery. What now? Discovering you have coronary artery disease can be overwhelming. But be encouraged. There are things you can do to manage and live with this condition. Reducing cholesterol, lowering blood pressure, quitting tobacco, eating healthier, exercising and managing your stress can make a world of difference. Better heart health starts by educating yourself. So don't be afraid to seek out information and ask your doctors about coronary artery disease. If you'd like to learn even more about this condition, watch our other related videos or visit Mayoclinic.org. We wish you well. Show transcript for video What is coronary artery disease? A Mayo Clinic cardiologist explains. Show transcript for video What is coronary artery disease? A Mayo Clinic cardiologist explains. {Music playing} Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: I'm Dr. Stephen Kopecky, a cardiologist at Mayo Clinic. In this video, we'll cover the basics of coronary artery disease. What is it? Who gets it? The symptoms, diagnosis and treatment. Whether you're looking for answers for yourself or someone you love, we're here to give you the best information available. Coronary artery disease, also called CAD, is a condition that affects your heart. It is the most common heart disease in the United States. CAD happens when coronary arteries struggle to supply the heart with enough blood, oxygen and nutrients. Cholesterol deposits, or plaques, are almost always to blame. These buildups narrow your arteries, decreasing blood flow to your heart. This can cause chest pain, shortness of breath or even a heart attack. CAD typically takes a long time to develop. So often, patients don't know that they have it until there's a problem. But there are ways to prevent coronary artery disease, and ways to know if you're at risk and ways to treat it. Who gets it? Anyone can develop CAD. It begins when fats, cholesterols and other substances gather along the walls of your arteries. This process is called atherosclerosis. It's typically no cause for concern. However, too much buildup can lead to a blockage, obstructing blood flow. There are a number of risk factors, common red flags, that can contribute to this and ultimately lead to coronary artery disease. First, getting older can mean more damaged and narrowed arteries. Second, men are generally at a greater risk. But the risk for women increases after menopause. Existing health conditions matter, too. High blood pressure can thicken your arteries, narrowing your blood flow. High cholesterol levels can increase the rate of plaque buildup. Diabetes is also associated with higher risk, as is being overweight. Your lifestyle plays a large role as well. Physical inactivity, long periods of unrelieved stress in your life, an unhealthy diet and smoking can all increase your risk. And finally, family history. If a close relative was diagnosed at an early age with heart disease, you're at a greater risk. All these factors together can paint a picture of your risk for developing CAD. What are the symptoms? When coronary arteries become narrow, the heart doesn't get enough oxygen-rich blood. Remember, unlike most pumps, the heart has to pump its own energy supply. It's working harder with less. And you may begin to notice these signs and symptoms of pressure or tightness in your chest. This pain is called angina. It may feel like somebody is standing on your chest. When your heart can't pump enough blood to meet your body's needs, you might develop shortness of breath or extreme fatigue during activities. And if an artery becomes totally blocked, it leads to a heart attack. Classic signs and symptoms of a heart attack include crushing, substernal chest pain, pain in your shoulders or arms, shortness of breath, and sweating. However, many heart attacks have minimal or no symptoms and are found later during routine testing. How is it diagnosed? Diagnosing CAD starts by talking to your doctor. They'll be able to look at your medical history, do a physical exam and order routine blood work. Depending on that, they may suggest one or more of the following tests: an electrocardiogram or ECG, an echocardiogram or soundwave test of the heart, stress test, cardiac catheterization and angiogram, or a cardiac CT scan. How is it treated? Treating coronary artery disease usually means making changes to your lifestyle. This might be eating healthier foods, exercising regularly, losing excess weight, reducing stress or quitting smoking. The good news is these changes can do a lot to improve your outlook. Living a healthier life translates to having healthier arteries. When necessary, treatment could involve drugs like aspirin, cholesterol-modifying medications, beta-blockers, or certain medical procedures like angioplasty or coronary artery bypass surgery. What now? Discovering you have coronary artery disease can be overwhelming. But be encouraged. There are things you can do to manage and live with this condition. Reducing cholesterol, lowering blood pressure, quitting tobacco, eating healthier, exercising and managing your stress can make a world of difference. Better heart health starts by educating yourself. So don't be afraid to seek out information and ask your doctors about coronary artery disease. If you'd like to learn even more about this condition, watch our other related videos or visit Mayoclinic.org. We wish you well. {Music playing} {Music playing} Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: I'm Dr. Stephen Kopecky, a cardiologist at Mayo Clinic. In this video, we'll cover the basics of coronary artery disease. What is it? Who gets it? The symptoms, diagnosis and treatment. Whether you're looking for answers for yourself or someone you love, we're here to give you the best information available. Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: Coronary artery disease, also called CAD, is a condition that affects your heart. It is the most common heart disease in the United States. CAD happens when coronary arteries struggle to supply the heart with enough blood, oxygen and nutrients. Cholesterol deposits, or plaques, are almost always to blame. These buildups narrow your arteries, decreasing blood flow to your heart. This can cause chest pain, shortness of breath or even a heart attack. CAD typically takes a long time to develop. So often, patients don't know that they have it until there's a problem. But there are ways to prevent coronary artery disease, and ways to know if you're at risk and ways to treat it. CAD CAD Who gets it? Anyone can develop CAD. It begins when fats, cholesterols and other substances gather along the walls of your arteries. This process is called atherosclerosis. It's typically no cause for concern. However, too much buildup can lead to a blockage, obstructing blood flow. There are a number of risk factors, common red flags, that can contribute to this and ultimately lead to coronary artery disease. First, getting older can mean more damaged and narrowed arteries. Second, men are generally at a greater risk. But the risk for women increases after menopause. Existing health conditions matter, too. High blood pressure can thicken your arteries, narrowing your blood flow. High cholesterol levels can increase the rate of plaque buildup. Diabetes is also associated with higher risk, as is being overweight. Your lifestyle plays a large role as well. Physical inactivity, long periods of unrelieved stress in your life, an unhealthy diet and smoking can all increase your risk. And finally, family history. If a close relative was diagnosed at an early age with heart disease, you're at a greater risk. All these factors together can paint a picture of your risk for developing CAD. CAD CAD What are the symptoms? When coronary arteries become narrow, the heart doesn't get enough oxygen-rich blood. Remember, unlike most pumps, the heart has to pump its own energy supply. It's working harder with less. And you may begin to notice these signs and symptoms of pressure or tightness in your chest. This pain is called angina. It may feel like somebody is standing on your chest. When your heart can't pump enough blood to meet your body's needs, you might develop shortness of breath or extreme fatigue during activities. And if an artery becomes totally blocked, it leads to a heart attack. Classic signs and symptoms of a heart attack include crushing, substernal chest pain, pain in your shoulders or arms, shortness of breath, and sweating. However, many heart attacks have minimal or no symptoms and are found later during routine testing. How is it diagnosed? Diagnosing CAD starts by talking to your doctor. They'll be able to look at your medical history, do a physical exam and order routine blood work. Depending on that, they may suggest one or more of the following tests: an electrocardiogram or ECG, an echocardiogram or soundwave test of the heart, stress test, cardiac catheterization and angiogram, or a cardiac CT scan. CAD CT How is it treated? Treating coronary artery disease usually means making changes to your lifestyle. This might be eating healthier foods, exercising regularly, losing excess weight, reducing stress or quitting smoking. The good news is these changes can do a lot to improve your outlook. Living a healthier life translates to having healthier arteries. When necessary, treatment could involve drugs like aspirin, cholesterol-modifying medications, beta-blockers, or certain medical procedures like angioplasty or coronary artery bypass surgery. What now? Discovering you have coronary artery disease can be overwhelming. But be encouraged. There are things you can do to manage and live with this condition. Reducing cholesterol, lowering blood pressure, quitting tobacco, eating healthier, exercising and managing your stress can make a world of difference. Better heart health starts by educating yourself. So don't be afraid to seek out information and ask your doctors about coronary artery disease. If you'd like to learn even more about this condition, watch our other related videos or visit Mayoclinic.org. We wish you well. Heart disease symptoms caused by irregular heartbeats (heart arrhythmias) The heart may beat too quickly, too slowly or irregularly. Heart arrhythmia symptoms can include: Chest pain or discomfort Dizziness Fainting (syncope) or near fainting Fluttering in the chest Lightheadedness Racing heartbeat (tachycardia) Shortness of breath Slow heartbeat (bradycardia) Heart disease symptoms caused by congenital heart defects Serious congenital heart defects usually are noticed soon after birth. Congenital heart defect symptoms in children could include: Pale gray or blue skin or lips (cyanosis) Swelling in the legs, belly area or areas around the eyes In an infant, shortness of breath during feedings, leading to poor weight gain Less-serious congenital heart defects are often not diagnosed until later in childhood or during adulthood. Symptoms of congenital heart defects that usually aren't immediately life-threatening include: Easily getting short of breath during exercise or activity Easily tiring during exercise or activity Swelling of the hands, ankles or feet Heart disease symptoms caused by diseased heart muscle (cardiomyopathy) Early stages of cardiomyopathy may not cause noticeable symptoms. As the condition worsens, symptoms may include: Dizziness, lightheadedness and fainting Fatigue Feeling short of breath during activity or at rest Feeling short of breath at night when trying to sleep or waking up short of breath Irregular heartbeats that feel rapid, pounding or fluttering Swollen legs, ankles or feet Heart disease symptoms caused by heart valve problems (valvular heart disease) The heart has four valves — the aortic, mitral, pulmonary and tricuspid valves. They open and close to move blood through the heart. Many things can damage the heart valves. A heart valve may become narrowed (stenosis), leaky (regurgitation or insufficiency) or close improperly (prolapse). Valvular heart disease is also called heart valve disease. Depending on which valve isn't working properly, heart valve disease symptoms generally include: Chest pain Fainting (syncope) Fatigue Irregular heartbeat Shortness of breath Swollen feet or ankles Endocarditis is an infection that affects the heart valves and inner lining of the heart chambers and heart valves (endocardium). Endocarditis symptoms can include: Dry or persistent cough Fever Heartbeat changes Shortness of breath Skin rashes or unusual spots Swelling of the legs or belly area Weakness or fatigue

heart-disease

Asthma attack signs and symptoms include: Severe shortness of breath, chest tightness or pain, and coughing or wheezing Low peak expiratory flow (PEF) readings, if you use a peak flow meter Symptoms that fail to respond to use of a quick-acting (rescue) inhaler Signs and symptoms of an asthma attack vary from person to person. Work with your doctor to identify your particular signs and symptoms of worsening asthma — and what to do when they occur. If your asthma symptoms don't improve or get worse after you take medication as your doctor directed, you may need emergency treatment. Your doctor can help you learn to recognize an asthma emergency so that you'll know when to get help.

asthma-attack

Collapse and loss of consciousness are the most common symptoms of ventricular fibrillation. Before a ventricular fibrillation episode, you may have symptoms of an irregularly fast or erratic heartbeat (arrhythmia). You may have: Chest pain Very fast heartbeat (tachycardia) Dizziness Nausea Shortness of breath

ventricular-fibrillation

Glioma symptoms depend on the location of the glioma. Symptoms also may depend on the type of glioma, its size and how quickly it's growing. Common signs and symptoms of gliomas include: Headache, particularly one that hurts the most in the morning. Nausea and vomiting. Confusion or a decline in brain function, such as problems with thinking and understanding information. Memory loss. Personality changes or irritability. Vision problems, such as blurred vision, double vision or loss of peripheral vision. Speech difficulties. Seizures, especially in someone who hasn't had seizures before.

glioma

If you develop a listeria infection, you might have: Fever Chills Muscle aches Nausea Diarrhea Symptoms might begin a few days after you've eaten contaminated food, but it can take 30 days or more before the first signs and symptoms of infection begin. If the listeria infection spreads to your nervous system, signs and symptoms can include: Headache Stiff neck Confusion or changes in alertness Loss of balance Convulsions Symptoms during pregnancy and in newborns During pregnancy, a listeria infection is likely to cause only mild signs and symptoms in the mother. The consequences for the baby, however, can be devastating — the baby can die in the womb or have a life-threatening infection within a few days of being born. Signs and symptoms of a listeria infection in a newborn can be subtle, but can include: Little interest in feeding Irritability Fever Vomiting Difficulty breathing

listeria-infection

Some people with aortic valve disease may not notice symptoms for many years. Signs and symptoms of aortic valve disease may include: Whooshing or swishing heart sound (heart murmur) Chest pain or tightness Dizziness Fainting Fatigue after activity or having less ability to be active Irregular heartbeat Shortness of breath, particularly during vigorous activity or when lying down Not eating enough (mainly in children with aortic valve stenosis) Not gaining enough weight (mainly in children with aortic valve stenosis)

aortic-valve-disease

Aphasia is a symptom of some other condition, such as a stroke or a brain tumor. A person with aphasia may: Speak in short or incomplete sentences Speak in sentences that don't make sense Substitute one word for another or one sound for another Speak unrecognizable words Have difficulty finding words Not understand other people's conversation Not understand what they read Write sentences that don't make sense Patterns of aphasia People with aphasia may have different strengths and weaknesses in their speech patterns. Sometimes these patterns are labeled as different types of aphasia, including: Broca's aphasia Wernicke aphasia Transcortical aphasia Conduction aphasia Mixed aphasia Global aphasia These patterns describe how well the person can understand what others say. They also describe how easy it is for the person to speak or to correctly repeat what someone else says. Aphasia may develop slowly over time. When that happens, the aphasia may be labeled with one of these names: Logopenic aphasia Semantic aphasia Agrammatism Many people with aphasia have patterns of speech difficulty that don't match these types. It may help to consider that each person with aphasia has unique symptoms, strengths and weaknesses rather than trying to label a particular type of aphasia.

aphasia

The signs and symptoms of Cushing syndrome can vary depending on the levels of excess cortisol. Common signs and symptoms of Cushing syndrome Weight gain and fatty tissue deposits, particularly around the midsection and upper back, in the face (moon face), and between the shoulders (buffalo hump) Pink or purple stretch marks (striae) on the skin of the abdomen, thighs, breasts and arms Thinning, fragile skin that bruises easily Slow healing of cuts, insect bites and infections Acne Signs and symptoms women with Cushing syndrome may experience Thicker or more visible body and facial hair (hirsutism) Irregular or absent menstrual periods Signs and symptoms men with Cushing syndrome may experience Decreased sex drive Decreased fertility Erectile dysfunction Other possible signs and symptoms of Cushing syndrome Severe fatigue Muscle weakness Depression, anxiety and irritability Loss of emotional control Cognitive difficulties New or worsened high blood pressure Headache Infections Skin darkening Bone loss, leading to fractures over time In children, impaired growth

cushing-syndrome

Facial paralysis Open pop-up dialog box Close Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Facial paralysis Open pop-up dialog box Facial paralysis Open pop-up dialog box Open pop-up dialog box Close Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Close Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Close Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Close Close Close Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Signs and symptoms of Bell's palsy come on suddenly and may include: Rapid onset of mild weakness to total paralysis on one side of your face — occurring within hours to days Facial droop and difficulty making facial expressions, such as closing your eye or smiling Drooling Pain around the jaw or in or behind your ear on the affected side Increased sensitivity to sound on the affected side Headache A loss of taste Changes in the amount of tears and saliva you produce In rare cases, Bell's palsy can affect the nerves on both sides of your face.

bells-palsy

The signs and symptoms of flu caused by the H1N1 virus are similar to those of infections caused by other flu strains and can include: Fever, but not always Chills Cough Sore throat Runny or stuffy nose Watery, red eyes Body aches Headache Fatigue Diarrhea Nausea and vomiting Flu symptoms develop about one to three days after you're exposed to the virus.

swine-flu

Patellofemoral pain syndrome usually causes a dull, aching pain in the front of the knee. The following can increase the pain: Walking up or down stairs. Kneeling or squatting. Sitting with a bent knee for long periods of time. When to see your doctor If the knee pain doesn't improve within a few days or it gets harder to move the knee, call your health care provider.

patellofemoral-pain-syndrome

Signs and symptoms of dumping syndrome generally occur within minutes after eating, especially after a meal rich in table sugar (sucrose) or fruit sugar (fructose). They include: Feeling bloated or too full after eating Nausea Vomiting Abdominal cramps Diarrhea Flushing Dizziness, lightheadedness Rapid heart rate Late dumping syndrome starts 1 to 3 hours after you eat a high-sugar meal. It takes time for signs and symptoms to develop because after you eat your body releases large amounts of insulin to absorb the sugars entering your small intestine. The result is low blood sugar. Signs and symptoms of late dumping syndrome can include: Sweating Flushing Dizziness, lightheadedness Weakness Rapid heart rate Some people have both early and late signs and symptoms. And dumping syndrome can develop years after surgery.

dumping-syndrome

Staph infection Open pop-up dialog box Close Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Staph infection Open pop-up dialog box Staph infection Open pop-up dialog box Open pop-up dialog box Close Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Close Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Close Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Close Close Close Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. MRSA Staph infections can range from minor skin problems to life-threatening illness. For example, endocarditis, a serious infection of the inner lining of your heart (endocardium) can be caused by staph bacteria. Signs and symptoms of staph infections vary widely, depending on the location and severity of the infection. Skin infections Skin infections caused by staph bacteria include: Boils. The most common type of staph infection is the boil. This is a pocket of pus that develops in a hair follicle or oil gland. The skin over the infected area usually becomes red and swollen. If a boil breaks open, it will probably drain pus. Boils occur most often under the arms or around the groin or buttocks. Impetigo. This contagious, often painful rash can be caused by staph bacteria. Impetigo usually has large blisters that may ooze fluid and develop a honey-colored crust. Cellulitis. Cellulitis is an infection of the deeper layers of skin. It causes redness and swelling on the surface of your skin. Sores or areas of oozing discharge may develop, too. Staphylococcal scalded skin syndrome. Toxins produced by the staph bacteria may cause staphylococcal scalded skin syndrome. Affecting mostly babies and children, this condition includes a fever, a rash and sometimes blisters. When the blisters break, the top layer of skin comes off. This leaves a red, raw surface that looks like a burn. Food poisoning Staph bacteria are one of the most common causes of food poisoning. The bacteria multiply in food and produce toxins that make you sick. Symptoms come on quickly, usually within hours of eating a contaminated food. Symptoms usually disappear quickly, too, often lasting just half a day. A staph infection in food usually doesn't cause a fever. Signs and symptoms you can expect with this type of staph infection include: Nausea and vomiting Diarrhea Dehydration Low blood pressure Bacteremia Also known as a bloodstream infection, bacteremia occurs when staph bacteria enter the bloodstream. A fever and low blood pressure are signs of bacteremia. The bacteria can travel to locations deep within your body to cause infections that affect: Internal organs, such as your brain (meningitis), heart (endocarditis) or lungs (pneumonia) Bones and muscles Surgically implanted devices, such as artificial joints or cardiac pacemakers Toxic shock syndrome This life-threatening condition results from toxins produced by some strains of staph bacteria. The condition has been linked to certain types of tampons, skin wounds and surgery. It usually develops suddenly with: A high fever Nausea and vomiting A rash on your palms and soles that looks like a sunburn Confusion Muscle aches Diarrhea Stomach pain Septic arthritis Septic arthritis is often caused by a staph infection. The bacteria often target the knees, shoulders, hips, and fingers or toes. Artificial joints may also be at risk of infection. Signs and symptoms may include: Joint swelling Severe pain in the affected joint Fever

staph-infections

The symptoms of a peripheral nerve tumor develop from direct effects on the main nerve or from the tumor pressing on nearby nerves, blood vessels or tissues. As the tumor grows, it may be more likely to cause symptoms, although tumor size doesn't always determine effects. Symptoms of peripheral nerve tumors vary depending on where the tumors are located and the tissues affected. They include: Swelling or a lump under the skin. Pain, tingling or numbness. Weakness or a loss of function in the affected area. Dizziness or a loss of balance.

peripheral-nerve-tumors

Achilles tendinitis Open pop-up dialog box Close Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis Open pop-up dialog box Achilles tendinitis Open pop-up dialog box Open pop-up dialog box Close Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Close Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Close Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Close Close Close Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. The pain associated with Achilles tendinitis typically begins as a mild ache in the back of the leg or above the heel after running or other sports activity. Episodes of more-severe pain may occur after prolonged running, stair climbing or sprinting. You might also experience tenderness or stiffness, especially in the morning, which usually improves with mild activity.

achilles-tendinitis

Signs and symptoms can vary greatly among girls and women with triple X syndrome. Many experience no noticeable effects or have only mild symptoms. Being taller than average height is the most typical physical feature. Most females with triple X syndrome experience normal sexual development and have the ability to become pregnant. Some girls and women with triple X syndrome have intelligence in the normal range, but possibly slightly lower when compared with siblings. Others may have intellectual disabilities and sometimes may have behavioral problems. Occasionally, significant symptoms may occur, which vary among individuals. These signs and symptoms may show up as: Delayed development of speech and language skills, as well as motor skills, such as sitting up and walking Learning disabilities, such as difficulty with reading, understanding or math Behavioral problems, such as attention-deficit/hyperactivity disorder (ADHD) or symptoms of autism spectrum disorder Psychological problems, such as anxiety and depression Problems with fine and gross motor skills, memory, judgment and information processing Sometimes females with triple X syndrome have these signs and symptoms: Vertical folds of skin that cover the inner corners of the eyes (epicanthal folds) Widely spaced eyes Curved pinky fingers Flat feet Breastbone with an inward bowed shape Weak muscle tone (hypotonia) Seizures Problems with the kidneys Ovaries that don't work properly at a young age (premature ovarian failure)

triple-x-syndrome

Schizophrenia involves a range of problems with thinking (cognition), behavior and emotions. Signs and symptoms may vary, but usually involve delusions, hallucinations or disorganized speech, and reflect an impaired ability to function. Symptoms may include: Delusions. These are false beliefs that are not based in reality. For example, you think that you're being harmed or harassed; certain gestures or comments are directed at you; you have exceptional ability or fame; another person is in love with you; or a major catastrophe is about to occur. Delusions occur in most people with schizophrenia. Hallucinations. These usually involve seeing or hearing things that don't exist. Yet for the person with schizophrenia, they have the full force and impact of a normal experience. Hallucinations can be in any of the senses, but hearing voices is the most common hallucination. Disorganized thinking (speech). Disorganized thinking is inferred from disorganized speech. Effective communication can be impaired, and answers to questions may be partially or completely unrelated. Rarely, speech may include putting together meaningless words that can't be understood, sometimes known as word salad. Extremely disorganized or abnormal motor behavior. This may show in a number of ways, from childlike silliness to unpredictable agitation. Behavior isn't focused on a goal, so it's hard to do tasks. Behavior can include resistance to instructions, inappropriate or bizarre posture, a complete lack of response, or useless and excessive movement. Negative symptoms. This refers to reduced or lack of ability to function normally. For example, the person may neglect personal hygiene or appear to lack emotion (doesn't make eye contact, doesn't change facial expressions or speaks in a monotone). Also, the person may lose interest in everyday activities, socially withdraw or lack the ability to experience pleasure. Symptoms can vary in type and severity over time, with periods of worsening and remission of symptoms. Some symptoms may always be present. In men, schizophrenia symptoms typically start in the early to mid-20s. In women, symptoms typically begin in the late 20s. It's uncommon for children to be diagnosed with schizophrenia and rare for those older than age 45. Symptoms in teenagers Schizophrenia symptoms in teenagers are similar to those in adults, but the condition may be more difficult to recognize. This may be in part because some of the early symptoms of schizophrenia in teenagers are common for typical development during teen years, such as: Withdrawal from friends and family A drop in performance at school Trouble sleeping Irritability or depressed mood Lack of motivation Also, recreational substance use, such as marijuana, methamphetamines or LSD, can sometimes cause similar signs and symptoms. Compared with schizophrenia symptoms in adults, teens may be: Less likely to have delusions More likely to have visual hallucinations

schizophrenia

Symptoms of de Quervain tenosynovitis include: Pain near the base of the thumb Swelling near the base of the thumb Difficulty moving the thumb and wrist when doing something that involves grasping or pinching A "sticking" or "stop-and-go" sensation in the thumb when moving it If the condition goes too long without treatment, the pain may spread farther into the thumb or forearm or both. Moving the thumb and wrist may make the pain worse.

de-quervain-tenosynovitis

Body lice bites can cause intense itching, and you may notice small areas of blood and crust on your skin at the site of the bite marks. See your doctor if improved hygiene doesn't remove the infestation, or if you develop a skin infection from scratching the bites.

body-lice

Anal cancer signs and symptoms include: Bleeding from the anus or rectum Pain in the area of the anus A mass or growth in the anal canal Anal itching

anal-cancer

The blisters associated with dyshidrosis occur most commonly on the sides of the fingers and the palms. Sometimes the soles of the feet also can be affected. The blisters are usually small — about the width of a standard pencil lead — and grouped in clusters, with an appearance similar to tapioca. In more-severe cases, the small blisters may merge to form larger blisters. Skin affected by dyshidrosis can be painful and very itchy. The blisters dry and flake off in about three weeks. Dyshidrosis tends to recur fairly regularly for months or years.

dyshidrosis

Signs and symptoms of carbon monoxide poisoning may include: Dull headache Weakness Dizziness Nausea or vomiting Shortness of breath Confusion Blurred vision Loss of consciousness Carbon monoxide poisoning can be particularly dangerous for people who are sleeping or intoxicated. People may have irreversible brain damage or even die before anyone realizes there's a problem.

carbon-monoxide

Niemann-Pick signs and symptoms may include: Clumsiness and difficulty walking Excessive muscle contractions (dystonia) or eye movements Sleep disturbances Difficulty swallowing and eating Recurrent pneumonia The three main types of Niemann-Pick are types A, B and C. The signs and symptoms you experience depend on the type and severity of your condition. Some infants with type A will show signs and symptoms within the first few months of life. Those with type B may not show signs for years and have a better chance of surviving to adulthood. People with type C may not experience any symptoms until adulthood.

niemann-pick

The brain, like the rest of the body, changes with age. Many people notice they become more forgetful as they age. It may take longer to think of a word or to recall a person's name. If concerns with mental function go beyond what's expected, the symptoms may be due to mild cognitive impairment (MCI). MCI may be the cause of changes in thinking if: MCI You forget things more often. You miss appointments or social events. You lose your train of thought. Or you can't follow the plot of a book or movie. You have trouble following a conversation. You find it hard to make decisions, finish a task or follow instructions. You start to have trouble finding your way around places you know well. You begin to have poor judgment. Your family and friends notice any of these changes. If you have MCI, you also may experience: MCI Depression Anxiety A short temper and aggression A lack of interest

mild-cognitive-impairment

Possible signs and symptoms of mesenteric lymphadenitis include: Abdominal pain, often centered on the lower right side, but the pain can be more widespread General abdominal tenderness Fever Mesenteric lymph node enlargement Depending on what's causing the ailment, signs and symptoms might also include: Diarrhea Nausea and vomiting

mesenteric-lymphadenitis

Signs and symptoms of appendicitis may include: Sudden pain that begins on the right side of the lower abdomen Sudden pain that begins around your navel and often shifts to your lower right abdomen Pain that worsens if you cough, walk or make other jarring movements Nausea and vomiting Loss of appetite Low-grade fever that may worsen as the illness progresses Constipation or diarrhea Abdominal bloating Flatulence The site of your pain may vary, depending on your age and the position of your appendix. When you're pregnant, the pain may seem to come from your upper abdomen because your appendix is higher during pregnancy.

appendicitis

Some people have no symptoms in the early stages of avascular necrosis. As the condition worsens, affected joints might hurt only when putting weight on them. Eventually, you might feel the pain even when you're lying down. Pain can be mild or severe. It usually develops gradually. Pain associated with avascular necrosis of the hip might center on the groin, thigh or buttock. Besides the hip, the shoulder, knee, hand and foot can be affected. Some people develop avascular necrosis on both sides, such as in both hips or in both knees.

avascular-necrosis

Common childhood asthma signs and symptoms include: Frequent coughing that worsens when your child has a viral infection, occurs while your child is asleep or is triggered by exercise or cold air A whistling or wheezing sound when breathing out Shortness of breath Chest congestion or tightness Childhood asthma might also cause: Trouble sleeping due to shortness of breath, coughing or wheezing Bouts of coughing or wheezing that get worse with a cold or the flu Delayed recovery or bronchitis after a respiratory infection Trouble breathing that hampers play or exercise Fatigue, which can be due to poor sleep Asthma signs and symptoms vary from child to child, and might get worse or better over time. Your child might have only one indication, such as a lingering cough or chest congestion. It can be difficult to tell whether your child's symptoms are caused by asthma. Periodic or long-lasting wheezing and other asthma-like symptoms can be caused by infectious bronchitis or another respiratory problem.

childhood-asthma

If you have bursitis, the affected joint might: Feel achy or stiff Hurt more when you move it or press on it Look swollen and red

bursitis

Small vessel disease signs and symptoms include: Chest pain, squeezing or discomfort (angina), which may get worse with activity or emotional stress Discomfort in the left arm, jaw, neck, back or abdomen along with chest pain Shortness of breath Tiredness and lack of energy If you've been treated for coronary artery disease with angioplasty and stents and your signs and symptoms haven't gone away, you might also have small vessel disease.

small-vessel-disease

Signs and symptoms of antiphospholipid syndrome can include: Blood clots in legs (DVT). Signs of a DVT include pain, swelling and redness. These clots can travel to the lungs (pulmonary embolism). Repeated miscarriages or stillbirths. Other complications of pregnancy include dangerously high blood pressure (preeclampsia) and premature delivery. Stroke. A stroke can occur in a young person who has antiphospholipid syndrome but no known risk factors for cardiovascular diseases. Transient ischemic attack (TIA). Similar to a stroke, a TIA usually lasts only a few minutes and causes no permanent damage. Rash. Some people develop a red rash with a lacy, net-like pattern. Less common signs and symptoms include: Neurological symptoms. Chronic headaches, including migraines; dementia and seizures are possible when a blood clot blocks blood flow to parts of the brain. Cardiovascular disease. Antiphospholipid syndrome can damage heart valves. Low blood platelet counts (thrombocytopenia). This decrease in blood cells needed for clotting can cause episodes of bleeding, particularly from the nose and gums. Bleeding into the skin will appear as patches of small red spots.

antiphospholipid-syndrome

Signs and symptoms of DiGeorge syndrome (22q11.2 deletion syndrome) can vary in type and severity, depending on what body systems are affected and how severe the defects are. Some signs and symptoms may be apparent at birth, but others may not appear until later in infancy or early childhood. Signs and symptoms may include some combination of the following: Heart murmur and bluish skin due to poor circulation of oxygen-rich blood (cyanosis) as a result of a heart defect Frequent infections Certain facial features, such as an underdeveloped chin, low-set ears, wide-set eyes or a narrow groove in the upper lip A gap in the roof of the mouth (cleft palate) or other problems with the palate Delayed growth Difficulty feeding, failure to gain weight or gastrointestinal problems Breathing problems Poor muscle tone Delayed development, such as delays in rolling over, sitting up or other infant milestones Delayed speech development or nasal-sounding speech Learning delays or disabilities Behavior problems When to see a doctor Other conditions may cause signs and symptoms similar to 22q11.2 deletion syndrome. So it's important to get an accurate and prompt diagnosis if your child shows any signs or symptoms listed above. Doctors may suspect 22q11.2 deletion syndrome: At birth. If certain conditions — a severe heart defect, cleft palate or a combination of other factors typical of 22q11.2 deletion syndrome — are readily apparent at birth, diagnostic tests will likely begin before your child leaves the hospital. At well-baby visits. Your family doctor or pediatrician may suspect the disorder because of a combination of illnesses or disorders that become apparent over time. Other issues may come to the attention of your doctor during regularly scheduled well-baby visits or annual checkups for your child.

digeorge-syndrome

Carpal tunnel syndrome symptoms usually start gradually and include: Tingling or numbness. You may notice tingling and numbness in the fingers or hand. Usually the thumb and index, middle or ring fingers are affected, but not the little finger. You might feel a sensation like an electric shock in these fingers. The sensation may travel from the wrist up the arm. These symptoms often occur while holding a steering wheel, phone or newspaper, or may wake you from sleep. Many people "shake out" their hands to try to relieve their symptoms. The numb feeling may become constant over time. Weakness. You may experience weakness in the hand and drop objects. This may be due to the numbness in the hand or weakness of the thumb's pinching muscles, which are also controlled by the median nerve.

carpal-tunnel-syndrome

Edema in foot and ankle Open pop-up dialog box Close Edema in foot and ankle Edema in foot and ankle Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Edema in foot and ankle Open pop-up dialog box Edema in foot and ankle Open pop-up dialog box Open pop-up dialog box Close Edema in foot and ankle Edema in foot and ankle Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Close Edema in foot and ankle Edema in foot and ankle Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Close Edema in foot and ankle Edema in foot and ankle Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Close Close Close Edema in foot and ankle Edema in foot and ankle Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Edema in foot and ankle Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Swelling of the foot, ankle and leg can be bad enough to leave a dimple, also known as a pit, in the skin after pressing on the area. This swelling, called edema, is the result of too much fluid in the tissues. Congestive heart failure or the vein not working well, also known as venous insufficiency, is often the cause. Symptoms of edema include: Swelling or puffiness of the tissue right under the skin, especially in legs or arms. Stretched or shiny skin. Skin that holds a dimple, also known as pitting, after it's been pressed for a few seconds. Increase in the size of the stomach area. Feeling of leg heaviness.

edema

Signs and symptoms of pheochromocytomas often include: High blood pressure Headache Heavy sweating Rapid heartbeat Tremors Pallor Shortness of breath Panic attack-type symptoms Less common signs or symptoms may include: Anxiety or sense of doom Blurry vision Constipation Weight loss Symptomatic spells The symptoms of pheochromocytoma may be constant, or they may occur, or get stronger, occasionally. These spells can happen because of activities or conditions, foods high in a substance that affects blood pressure (tyramine), and medications. Certain activities or conditions can make symptoms worse, such as: Certain activities or conditions Physical hard work Anxiety or stress Changes in body position, such as going from sitting or lying down to standing Labor and delivery Surgery and a drug that causes you to be in a sleep-like state during surgery (anesthesia) Foods high in tyramine, a substance that affects blood pressure, also can make symptoms worse. Tyramine is common in foods that are fermented, aged, pickled, cured, overripe or spoiled. These foods include: Foods high in tyramine, Some cheeses Some beers and wines Chocolate Dried or smoked meats Certain medications that can make symptoms worse include: Certain medications Monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil), tranylcypromine (Parnate) and isocarboxazid (Marplan) Stimulants, such as amphetamines or cocaine When to see a doctor Although high blood pressure is a primary sign of a pheochromocytoma, most people who have high blood pressure don't have an adrenal tumor. Talk to your health care provider if any of these factors apply to you: Difficulty controlling high blood pressure with current treatment Spells of worsening high blood pressure A family history of pheochromocytoma A family history of a related genetic disorder: multiple endocrine neoplasia, type 2 (MEN 2), von Hippel-Lindau disease, hereditary paraganglioma syndromes or neurofibromatosis 1

pheochromocytoma

Most people infected with ascariasis have no signs or symptoms. Moderate to heavy infestations cause various signs or symptoms, depending on which part of your body is affected. In the lungs After you swallow the tiny (microscopic) ascariasis eggs, they hatch in the small intestine and the larvae migrate through the bloodstream or lymphatic system into the lungs. At this stage, you may experience signs and symptoms similar to asthma or pneumonia, including: Persistent cough Shortness of breath Wheezing After spending 10 to 14 days in the lungs, the larvae travel to the throat, where you cough them up and then swallow them. In the intestines The larvae mature into adult worms in the small intestine, and the adult worms typically live in the intestines until they die. In mild or moderate ascariasis, the intestinal infestation can cause: Vague abdominal pain Nausea and vomiting Diarrhea or bloody stools If you have a large number of worms in the intestine, you might have: Severe abdominal pain Fatigue Vomiting Weight loss or malnutrition A worm in your vomit or stool

ascariasis

Schizoaffective disorder symptoms may vary from person to person. People with the condition experience psychotic symptoms, such as hallucinations or delusions, as well as symptoms of a mood disorder — either bipolar type (episodes of mania and sometimes depression) or depressive type (episodes of depression). Although the development and course of schizoaffective disorder may vary, defining features include a major mood episode (depressed or manic mood) and at least a two-week period of psychotic symptoms when a major mood episode is not present. Signs and symptoms of schizoaffective disorder depend on the type — bipolar or depressive type — and may include, among others: Delusions — having false, fixed beliefs, despite evidence to the contrary Hallucinations, such as hearing voices or seeing things that aren't there Impaired communication and speech, such as being incoherent Bizarre or unusual behavior Symptoms of depression, such as feeling empty, sad or worthless Periods of manic mood, with an increase in energy and a decreased need for sleep over several days, and behaviors that are out of character Impaired occupational, academic and social functioning Problems with managing personal care, including cleanliness and physical appearance

schizoaffective-disorder

Buerger's disease symptoms include: Tingling or numbness in the hands or feet. Pale, reddish or blue-tinted hands or feet. Pain that may come and go in your legs and feet or in your arms and hands. This pain may occur when you use your hands or feet and eases when you stop that activity (claudication), or when you're at rest. Inflammation along a vein just below the skin's surface (due to a blood clot in the vein). Fingers and toes that turn pale when exposed to cold (Raynaud's phenomenon). Painful open sores on your fingers and toes.

buergers-disease

Signs and symptoms of shigella infection usually begin a day or two after contact with shigella. But it may take up to a week to develop. Signs and symptoms may include: Diarrhea (often containing blood or mucus) Stomach pain or cramps Fever Nausea or vomiting Symptoms generally last for about five to seven days. In some cases, symptoms may last longer. Some people have no symptoms after they've been infected with shigella. However, their feces may still be contagious up to a few weeks.

shigella

The symptoms of narcolepsy may get worse during the first few years of the disorder. Then they continue for life. They include: Excessive daytime sleepiness. People with narcolepsy fall asleep without warning. It can happen anywhere and at any time. It may happen when you're bored or during a task. For example, you may be working or talking with friends and suddenly fall asleep. It can be especially dangerous if you fall asleep while driving. You might fall asleep for only a few minutes or up to a half-hour. After waking, you'll often feel refreshed but you'll get sleepy again. You also may experience a decrease in how alert and focused you feel during the day. Daytime sleepiness often is the first symptom to appear. Feeling sleepy makes it hard to focus and function. Some people with narcolepsy continue doing a task when they fall asleep briefly. For example, you may fall asleep while writing, typing or driving. You might continue to perform that task while asleep. When you awaken, you can't remember what you did, and you probably didn't do it well. Sudden loss of muscle tone. This condition is called cataplexy. It can cause slurred speech or complete weakness of most muscles. Symptoms may last up to a few minutes. Cataplexy can't be controlled. It's triggered by intense emotions. Often the emotions that cause cataplexy are positive. Laughter or excitement may cause the symptoms. But sometimes fear, surprise or anger can cause the loss of muscle tone. For example, when you laugh, your head may drop without your control. Or your knees may suddenly lose strength, causing you to fall. Some people with narcolepsy experience only one or two episodes of cataplexy a year. Others have several episodes a day. Not everyone with narcolepsy has these symptoms. Sleep paralysis. People with narcolepsy often experience sleep paralysis. During sleep paralysis, you can't move or speak while falling asleep or upon waking. It's usually brief — lasting a few seconds or minutes. But it can be scary. You may be aware of it happening and can recall it afterward. Not everyone with sleep paralysis has narcolepsy. Hallucinations. Sometimes people see things that aren't there during sleep paralysis. Hallucinations also may happen in bed without sleep paralysis. These are called hypnagogic hallucinations if they happen as you fall asleep. They're called hypnopompic hallucinations if they happen upon waking. For example, you might feel as if there is a stranger in your bedroom. These hallucinations may be vivid and frightening because you may not be fully asleep when you begin dreaming. Changes in rapid eye movement (REM) sleep. REM sleep is when most dreaming happens. Typically, people enter REM sleep 60 to 90 minutes after falling asleep. But people with narcolepsy often move more quickly to REM sleep. They tend to enter REM sleep within 15 minutes of falling asleep. REM sleep also can happen at any time of the day. Other characteristics People with narcolepsy may have other sleep disorders. They might have obstructive sleep apnea, in which breathing starts and stops during the night. Or they may act out their dreams, known as REM sleep behavior disorder. Or they may have trouble falling asleep or staying asleep, called insomnia.

narcolepsy

Signs and symptoms of autoimmune hepatitis vary from person to person and may come on suddenly. Some people have few, if any, recognized problems in the early stages of the disease, whereas others experience signs and symptoms that may include: Fatigue Abdominal discomfort Yellowing of the skin and whites of the eyes (jaundice) An enlarged liver Abnormal blood vessels on the skin (spider angiomas) Skin rashes Joint pains Loss of menstrual periods

autoimmune-hepatitis

Patent ductus arteriosus symptoms (PDA) depend on the size of the opening and the person's age. A small PDA might not cause symptoms. Some people don't notice symptoms until adulthood. A large PDA can cause symptoms of heart failure soon after birth. PDA PDA A large PDA found during infancy or childhood might cause: PDA Poor eating, which leads to poor growth. Sweating with crying or eating. Persistent fast breathing or breathlessness. Easy tiring. Rapid heart rate.

patent-ductus-arteriosus

A popliteal artery aneurysm may not cause any noticeable symptoms. The first symptom may be pain the lower leg that occurs with walking (claudication). Other signs and symptoms of a popliteal artery aneurysm include: Knee pain Lower leg pain Swelling behind the knee Pulsing sensation behind the knee Causes An aneurysm is a ballooning in a weak spot in an artery wall. Many different things can cause the popliteal artery wall to become weak, including: Clogged arteries (atherosclerosis) High blood pressure Wear and tear of the popliteal artery due to repetitive use of the knee joint Weakening of the artery wall Risk factors Popliteal artery aneurysms are rare. They are more common in men than in women. Popiteal artery aneurysms often occur in men with abdominal aortic aneurysm (AAA), a swelling of the wall of the body's main artery (aorta). Anyone diagnosed with popliteal artery aneurysm should be screened for AAA. AAA Other risk factors for popliteal artery aneurysm include: Increasing age High blood pressure (hypertension) Smoking Narrowing of a heart valve (stenotic disease) Having three or more aneurysms anywhere in the body Complications Complications of popliteal artery aneurysm include blood clots (thrombosis) and, rarely, rupture of the aneurysm. Thrombosis of a popliteal artery aneurysm can cause a severe lack of blood flow (ischemia) in the lower leg, which may result in loss of the limb. Sudden leg ischemia can cause the following signs and symptoms: A change in skin color in the affected area No pulse behind the knee Skin in the affected area feels cold Numbness in the leg Inability to move the foot The risk of popliteal artery aneurysm rupture is low. Prevention Smoking and high blood pressure (hypertension) increase the risk of blood vessel (vascular) problems that can lead to popliteal artery and other aneurysms. Following a heart-healthy lifestyle — such as not smoking, eating a nutritious diet and getting regular exercise — can help prevent heart disease and blood vessel damage. By Mayo Clinic Staff By Mayo Clinic Staff Popliteal artery aneurysm care at Mayo Clinic

popliteal-artery-aneurysm

Signs and symptoms of hearing loss may include: Muffling of speech and other sounds Difficulty understanding words, especially against background noise or in a crowd Trouble hearing consonants Frequently asking others to speak more slowly, clearly and loudly Needing to turn up the volume of the television or radio Withdrawal from conversations Avoidance of some social settings

hearing-loss

Nasal polyps are associated with irritation and swelling (inflammation) of the lining of your nasal passages and sinuses that lasts more than 12 weeks (chronic sinusitis). However, it's possible to have chronic sinusitis without nasal polyps. Nasal polyps themselves are soft and lack sensation, so if they're small, you may not be aware you have them. Multiple growths or a large polyp may block your nasal passages and sinuses. Common signs and symptoms of chronic sinusitis with nasal polyps include: A runny nose Persistent stuffiness Postnasal drip Decreased or absent sense of smell Loss of sense of taste Facial pain or headache Pain in your upper teeth A sense of pressure over your forehead and face Snoring Frequent nosebleeds

nasal-polyps

Primary progressive aphasia symptoms vary, depending on which portion of the brain's language areas are involved. The condition has three types, which cause different symptoms. Semantic variant primary progressive aphasia Signs and symptoms include: Difficulty comprehending spoken or written language, particularly single words Trouble comprehending word meanings Struggling to name objects Logopenic variant primary progressive aphasia Signs and symptoms include: Difficulty retrieving words and word substitutions Frequently pausing in speech while searching for words Difficulty repeating phrases or sentences Nonfluent-agrammatic variant primary progressive aphasia Signs and symptoms include: Poor grammar in written and spoken form Trouble understanding complex sentences Using grammar incorrectly May be accompanied by speaking problems such as errors in speech sounds (known as apraxia of speech) Causes Primary progressive aphasia is caused by a shrinking (atrophy) of certain sections (lobes) of the brain responsible for speech and language. In this case, the frontal, temporal or parietal lobes, primarily on the left side of the brain, are affected. Atrophy is associated with the presence of abnormal proteins, and brain activity or function in affected areas might be reduced. Risk factors Risk factors for primary progressive aphasia include: Learning disabilities. If you had a childhood learning disability, particularly developmental dyslexia, you might be at somewhat higher risk of primary progressive aphasia. Certain gene mutations. Rare gene mutations have been linked to the disorder. If other members of your family have had primary progressive aphasia, you might be more likely to develop it. Complications People with primary progressive aphasia eventually lose the ability to speak and write, and to understand written and spoken language. Some people develop substantial difficulty forming sounds to speak (a problem called apraxia of speech), even when their ability to write and comprehend are not significantly impaired. As the disease progresses, other mental skills, such as memory, can become impaired. Some people develop other neurological symptoms such as problems with movement. With these complications, the affected person eventually will need help with day-to-day care. People with primary progressive aphasia can also develop depression or behavioral or social problems as the disease progresses. Other problems might include blunted emotions such as unconcern, poor judgment or inappropriate social behavior. By Mayo Clinic Staff By Mayo Clinic Staff Primary progressive aphasia care at Mayo Clinic

primary-progressive-aphasia

During sleep, symptoms of pediatric sleep apnea might include: Snoring. Pauses in breathing. Restless sleep. Snorting, coughing or choking. Mouth breathing. Nighttime sweating. Bed-wetting. Sleep terrors. Infants and young children with obstructive sleep apnea don't always snore. They might just have disturbed sleep. During the day, children with sleep apnea might: Perform poorly in school. Have trouble paying attention. Have learning problems. Have behavioral problems. Have poor weight gain. Be hyperactive.

pediatric-sleep-apnea

Symptoms of truncus arteriosus usually occur in the first few days of life. They include: Blue or gray skin due to low oxygen levels. Excessive sleepiness. Poor feeding. Poor growth. Pounding heartbeat. Fast breathing. Shortness of breath.

truncus-arteriosus

There are four main types of diabetic neuropathy. You can have one type or more than one type of neuropathy. Your symptoms depend on the type you have and which nerves are affected. Usually, symptoms develop gradually. You may not notice anything is wrong until considerable nerve damage has occurred. Peripheral neuropathy This type of neuropathy may also be called distal symmetric peripheral neuropathy. It's the most common type of diabetic neuropathy. It affects the feet and legs first, followed by the hands and arms. Signs and symptoms of peripheral neuropathy are often worse at night, and may include: Numbness or reduced ability to feel pain or temperature changes Tingling or burning feeling Sharp pains or cramps Muscle weakness Extreme sensitivity to touch — for some people, even a bedsheet's weight can be painful Serious foot problems, such as ulcers, infections, and bone and joint damage Autonomic neuropathy The autonomic nervous system controls blood pressure, heart rate, sweating, eyes, bladder, digestive system and sex organs. Diabetes can affect nerves in any of these areas, possibly causing signs and symptoms including: A lack of awareness that blood sugar levels are low (hypoglycemia unawareness) Drops in blood pressure when rising from sitting or lying down that may cause dizziness or fainting (orthostatic hypotension) Bladder or bowel problems Slow stomach emptying (gastroparesis), causing nausea, vomiting, sensation of fullness and loss of appetite Difficulty swallowing Changes in the way the eyes adjust from light to dark or far to near Increased or decreased sweating Problems with sexual response, such as vaginal dryness in women and erectile dysfunction in men Proximal neuropathy (diabetic polyradiculopathy) This type of neuropathy often affects nerves in the thighs, hips, buttocks or legs. It can also affect the abdominal and chest area. Symptoms are usually on one side of the body, but may spread to the other side. Proximal neuropathy may include: Severe pain in the buttock, hip or thigh Weak and shrinking thigh muscles Difficulty rising from a sitting position Chest or abdominal wall pain Mononeuropathy (focal neuropathy) Mononeuropathy refers to damage to a single, specific nerve. The nerve may be in the face, torso, arm or leg. Mononeuropathy may lead to: Difficulty focusing or double vision Paralysis on one side of the face Numbness or tingling in the hand or fingers Weakness in the hand that may result in dropping things Pain in the shin or foot Weakness causing difficulty lifting the front part of the foot (foot drop) Pain in the front of the thigh

diabetic-neuropathy

Ingrown toenail symptoms include: Pain and tenderness Inflamed skin Swelling Infection

ingrown-toenails

Moles Open pop-up dialog box Close Moles Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Moles Open pop-up dialog box Moles Open pop-up dialog box Open pop-up dialog box Close Moles Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Close Moles Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Close Moles Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Close Close Close Moles Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Melanoma Open pop-up dialog box Close Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Melanoma Open pop-up dialog box Melanoma Open pop-up dialog box Open pop-up dialog box Close Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Close Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Close Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Close Close Close Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Melanomas can develop anywhere on your body. They most often develop in areas that have had exposure to the sun, such as your back, legs, arms and face. Melanomas can also occur in areas that don't receive much sun exposure, such as the soles of your feet, palms of your hands and fingernail beds. These hidden melanomas are more common in people with darker skin. The first melanoma signs and symptoms often are: A change in an existing mole The development of a new pigmented or unusual-looking growth on your skin Melanoma doesn't always begin as a mole. It can also occur on otherwise normal-appearing skin. Normal moles Normal moles are generally a uniform color — such as tan, brown or black — with a distinct border separating the mole from your surrounding skin. They're oval or round and usually smaller than 1/4 inch (about 6 millimeters) in diameter — the size of a pencil eraser. Most moles begin appearing in childhood and new moles may form until about age 40. By the time they are adults, most people have between 10 and 40 moles. Moles may change in appearance over time and some may even disappear with age. Unusual moles that may indicate melanoma To help you identify characteristics of unusual moles that may indicate melanomas or other skin cancers, think of the letters ABCDE: A is for asymmetrical shape. Look for moles with irregular shapes, such as two very different-looking halves. B is for irregular border. Look for moles with irregular, notched or scalloped borders — characteristics of melanomas. C is for changes in color. Look for growths that have many colors or an uneven distribution of color. D is for diameter. Look for new growth in a mole larger than 1/4 inch (about 6 millimeters). E is for evolving. Look for changes over time, such as a mole that grows in size or that changes color or shape. Moles may also evolve to develop new signs and symptoms, such as new itchiness or bleeding. Cancerous (malignant) moles vary greatly in appearance. Some may show all of the changes listed above, while others may have only one or two unusual characteristics. Hidden melanomas Melanomas can also develop in areas of your body that have little or no exposure to the sun, such as the spaces between your toes and on your palms, soles, scalp or genitals. These are sometimes referred to as hidden melanomas because they occur in places most people wouldn't think to check. When melanoma occurs in people with darker skin, it's more likely to occur in a hidden area. Hidden melanomas include: Melanoma under a nail. Acral-lentiginous melanoma is a rare form of melanoma that can occur under a fingernail or toenail. It can also be found on the palms of the hands or the soles of the feet. It's more common in people of Asian descent, black people and in others with dark skin pigment. Melanoma in the mouth, digestive tract, urinary tract or vagina. Mucosal melanoma develops in the mucous membrane that lines the nose, mouth, esophagus, anus, urinary tract and vagina. Mucosal melanomas are especially difficult to detect because they can easily be mistaken for other far more common conditions. Melanoma in the eye. Eye melanoma, also called ocular melanoma, most often occurs in the uvea — the layer beneath the white of the eye (sclera). An eye melanoma may cause vision changes and may be diagnosed during an eye exam.

melanoma

Symptoms of spinal AVM can differ from person to person. Symptoms depend on where the AVM is found and how severe it is. Some people may not notice symptoms for many years, if at all. Others may experience symptoms that are debilitating or life-threatening. AVM AVM Symptoms usually develop when people are in their 20s, although almost 20% of people diagnosed with spinal AVM are under the age of 16. AVM Symptoms may start suddenly or slowly. Symptoms usually include: Problems with walking or climbing stairs Numbness, tingling or sudden pain in the legs Weakness on one or both sides of the body As the condition gets worse, you may have more symptoms including: Sudden, severe back pain Lack of feeling in the legs Difficulty urinating or having bowel movements Headache Stiff neck Sensitivity to light

spinal-arteriovenous-malformation

Signs and symptoms of functional neurologic disorder may vary, depending on the type of functional neurological symptoms, and they're significant enough to cause impairment and warrant medical evaluation. Symptoms can affect body movement and function and the senses. Signs and symptoms that affect body movement and function may include: Weakness or paralysis Abnormal movement, such as tremors or difficulty walking Loss of balance Difficulty swallowing or feeling "a lump in the throat" Seizures or episodes of shaking and apparent loss of consciousness (nonepileptic seizures) Episodes of unresponsiveness Signs and symptoms that affect the senses may include: Numbness or loss of the touch sensation Speech problems, such as the inability to speak or slurred speech Vision problems, such as double vision or blindness Hearing problems or deafness Cognitive difficulties involving memory and concentration

conversion-disorder

Nipple changes Open pop-up dialog box Close Nipple changes Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Nipple changes Open pop-up dialog box Nipple changes Open pop-up dialog box Open pop-up dialog box Close Nipple changes Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Close Nipple changes Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Close Nipple changes Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Close Close Close Nipple changes Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Signs and symptoms of breast cancer may include: A breast lump or thickening that feels different from the surrounding tissue Change in the size, shape or appearance of a breast Changes to the skin over the breast, such as dimpling A newly inverted nipple Peeling, scaling, crusting or flaking of the pigmented area of skin surrounding the nipple (areola) or breast skin Redness or pitting of the skin over your breast, like the skin of an orange

breast-cancer

Spinal stenosis often causes no symptoms. When symptoms do occur, they start slowly and get worse over time. Symptoms depend on which part of the spine is affected. In the lower back Spinal stenosis in the lower back can cause pain or cramping in one or both legs. This happens when you stand for a long time or when you walk. Symptoms get better when you bend forward or sit. Some people also have back pain. In the neck Spinal stenosis in the neck can cause: Numbness Tingling or weakness in a hand, leg, foot or arm Problems with walking and balance Neck pain Problems with the bowel or bladder

spinal-stenosis

Signs and symptoms depend on the type of dissociative disorders you have, but may include: Memory loss (amnesia) of certain time periods, events, people and personal information A sense of being detached from yourself and your emotions A perception of the people and things around you as distorted and unreal A blurred sense of identity Significant stress or problems in your relationships, work or other important areas of your life Inability to cope well with emotional or professional stress Mental health problems, such as depression, anxiety, and suicidal thoughts and behaviors There are three major dissociative disorders defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), published by the American Psychiatric Association: Dissociative amnesia. The main symptom is memory loss that's more severe than normal forgetfulness and that can't be explained by a medical condition. You can't recall information about yourself or events and people in your life, especially from a traumatic time. Dissociative amnesia can be specific to events in a certain time, such as intense combat, or more rarely, can involve complete loss of memory about yourself. It may sometimes involve travel or confused wandering away from your life (dissociative fugue). An episode of amnesia usually occurs suddenly and may last minutes, hours, or rarely, months or years. Dissociative identity disorder. Formerly known as multiple personality disorder, this disorder is characterized by "switching" to alternate identities. You may feel the presence of two or more people talking or living inside your head, and you may feel as though you're possessed by other identities. Each identity may have a unique name, personal history and characteristics, including obvious differences in voice, gender, mannerisms and even such physical qualities as the need for eyeglasses. There also are differences in how familiar each identity is with the others. People with dissociative identity disorder typically also have dissociative amnesia and often have dissociative fugue. Depersonalization-derealization disorder. This involves an ongoing or episodic sense of detachment or being outside yourself — observing your actions, feelings, thoughts and self from a distance as though watching a movie (depersonalization). Other people and things around you may feel detached and foggy or dreamlike, time may be slowed down or sped up, and the world may seem unreal (derealization). You may experience depersonalization, derealization or both. Symptoms, which can be profoundly distressing, may last only a few moments or come and go over many years. When to see a doctor Some people with dissociative disorders present in a crisis with traumatic flashbacks that are overwhelming or associated with unsafe behavior. People with these symptoms should be seen in an emergency room. If you or a loved one has less urgent symptoms that may indicate a dissociative disorder, call your doctor. Suicidal thoughts or behavior If you have thoughts of hurting yourself or someone else, call 911 or your local emergency number immediately, go to an emergency room, or confide in a trusted relative or friend. Or contact a suicide hotline. In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline, available 24 hours a day, seven days a week. Or use the Lifeline Chat. Services are free and confidential.

dissociative-disorders

Signs and symptoms of tongue-tie include: Difficulty lifting the tongue to the upper teeth or moving the tongue from side to side Trouble sticking out the tongue past the lower front teeth A tongue that appears notched or heart shaped when stuck out

tongue-tie

In some cases, a Baker cyst causes no pain, and you may not notice it. If you do have symptoms, they might include: Swelling behind the knee, and sometimes in the leg Knee pain Stiffness and inability to fully flex the knee The symptoms may be worse after you've been active or if you've been standing for a long time.

bakers-cyst

An allergic reaction (contact dermatitis) usually begins within hours to days after exposure to nickel. The reaction may last as long as 2 to 4 weeks. The reaction tends to occur only where your skin came into contact with nickel, but sometimes may appear in other places on your body. Nickel allergy signs and symptoms include: Rash or bumps on the skin Itching, which may be severe Redness or changes in skin color Dry patches of skin that may resemble a burn Blisters and draining fluid in severe cases

nickel-allergy

Signs and symptoms of Noonan syndrome vary greatly among individuals and may be mild to severe. Characteristics may be related to the specific gene containing the mutation. Facial features Facial appearance is one of the key clinical features that leads to a diagnosis of Noonan syndrome. These features may be more pronounced in infants and young children, but change with age. In adulthood, these distinct features become more subtle. Features may include the following: Eyes are wide-set and down-slanting with droopy lids. Irises are pale blue or green. Ears are low-set and rotated backward. Nose is depressed at the top, with a wide base and bulbous tip. Mouth has a deep groove between the nose and the mouth and wide peaks in the upper lip. The crease that runs from the edge of the nose to the corner of the mouth becomes deeply grooved with age. Teeth may be crooked, the inside roof of the mouth (palate) may be highly arched and the lower jaw may be small. Facial features may appear coarse, but appear sharper with age. The face may appear droopy and expressionless. Head may appear large with a prominent forehead and a low hairline on the back of the head. Skin may appear thin and transparent with age. Heart disease Many people with Noonan syndrome are born with some form of heart defect (congenital heart disease), accounting for some of the key signs and symptoms of the disorder. Some heart problems can occur later in life. Some forms of congenital heart disease associated with this disorder include: Valve disorders. Pulmonary valve stenosis is a narrowing of the pulmonary valve, the flap of tissue that separates the lower right chamber (ventricle) of the heart from the artery that supplies blood to the lungs (pulmonary artery). It's the most common heart problem seen with Noonan syndrome, and it may occur alone or with other heart defects. Thickening of the heart muscle (hypertrophic cardiomyopathy). This is abnormal growth or thickening of the heart muscle that affects some people with Noonan syndrome. Other structural defects of the heart. The defects can involve a hole in the wall that separates the two lower chambers of the heart (ventricular septal defect), narrowing of the artery that carries blood to the lungs for oxygen (pulmonary artery stenosis), or narrowing of the major blood vessel (aorta) that carries blood from the heart to the body (aortic coarctation). Irregular heart rhythm. This can occur with or without structural heart abnormalities. Irregular heart rhythm occurs in the majority of people with Noonan syndrome. Growth issues Noonan syndrome can affect normal growth. Many children with Noonan syndrome don't grow at a normal rate. Issues may include the following: Birth weight will likely be normal, but growth slows over time. Eating difficulties may result in inadequate nutrition and poor weight gain. Growth hormone levels may be insufficient. The growth spurt that's usually seen during the teenage years may be delayed. But because this disorder causes bone maturity to be delayed, growth sometimes continues into the late teens. By adulthood, some people with Noonan syndrome may have normal height, but short stature is more common. Musculoskeletal issues Some common issues can include: An unusually shaped chest often with a sunken sternum (pectus excavatum) or raised sternum (pectus carinatum) Wide-set nipples Short neck, often with extra folds of skin (webbed neck) or prominent neck muscles (trapezius) Deformities of the spine Learning disabilities Intelligence isn't affected for most people with Noonan syndrome. However, individuals may have: An increased risk of learning disabilities and mild intellectual disability A wide range of mental, emotional and behavioral issues that are usually mild Hearing and vision deficits that may complicate learning Eye conditions A common sign of Noonan syndrome is abnormalities of the eyes and eyelids. These may include: Problems with the eye muscles, such as cross-eye (strabismus) Refractive problems, such as astigmatism, nearsightedness (myopia) or farsightedness (hyperopia) Rapid movement of the eyeballs (nystagmus) Cataracts Hearing problems Noonan syndrome can cause hearing deficits due to nerve issues or to structural abnormalities in the inner ear bones. Bleeding Noonan syndrome can cause excessive bleeding and bruising due to clotting defects or having too few platelets. Lymphatic conditions Noonan syndrome can cause problems with the lymphatic system, which drains excess fluid from the body and helps fight infection. These problems: May show up before or after birth or develop in the teenage years or adulthood Can be focused in a particular area of the body or widespread Most commonly cause excess fluid (lymphedema) on the back of the hands or top of the feet Genital and kidney conditions Many people, especially males, with Noonan syndrome can have problems with the genitals and kidneys. Testicles. Undescended testicles (cryptorchidism) are common in males. Puberty. Puberty may be delayed in both boys and girls. Fertility. Most females develop normal fertility. In males, however, fertility may not develop normally, often because of undescended testicles. Kidneys. Kidney problems are generally mild and occur in a fairly small number of people with Noonan syndrome. Skin conditions People with Noonan syndrome may have skin conditions, which most commonly are: Various problems that affect the color and texture of the skin Curly, coarse hair or sparse hair When to see a doctor The signs and symptoms of Noonan syndrome can be subtle. If you suspect you or your child may have the disorder, see your primary care doctor or your child's pediatrician. You or your child may be referred to a geneticist or a cardiologist. If your unborn child is at risk because of a family history of Noonan syndrome, prenatal tests may be available.

noonan-syndrome

Signs and symptoms of trachoma usually affect both eyes and may include: Mild itching and irritation of the eyes and eyelids Eye discharge containing mucus or pus Eyelid swelling Light sensitivity (photophobia) Eye pain Eye redness Vision loss Young children are particularly susceptible to infection. But the disease progresses slowly, and the more painful symptoms may not emerge until adulthood. The World Health Organization (WHO) has identified five stages in the development of trachoma: Inflammation — follicular. The early infection has five or more follicles — small bumps that contain lymphocytes, a type of white blood cell — visible with magnification on the inner surface of your upper eyelid (conjunctiva). Inflammation — intense. In this stage, your eye is now highly infectious and becomes irritated, with a thickening or swelling of the upper eyelid. Eyelid scarring. Repeated infections lead to scarring of the inner eyelid. The scars often appear as white lines when examined with magnification. Your eyelid may become distorted and may turn in (entropion). In-turned eyelashes (trichiasis). The scarred inner lining of your eyelid continues to deform, causing your lashes to turn in so that they rub on and scratch the transparent outer surface of your eye (cornea). Corneal clouding (opacity). The cornea becomes affected by an inflammation that is most commonly seen under your upper lid. Continuous inflammation compounded by scratching from the in-turned lashes leads to clouding of the cornea. All the signs of trachoma are more severe in your upper lid than in your lower lid. Without intervention, a disease process that begins in childhood can continue to advance into adulthood.

trachoma

Signs and symptoms of a broken nose include: Pain or tenderness, especially when touching your nose Swelling of your nose and surrounding areas Bleeding from your nose Bruising around your nose or eyes Crooked or misshapen nose Difficulty breathing through your nose Discharge of mucus from your nose Feeling that one or both of your nasal passages are blocked

broken-nose

Yeast infection symptoms can range from mild to moderate, and include: Itching and irritation in the vagina and vulva A burning sensation, especially during intercourse or while urinating Redness and swelling of the vulva Vaginal pain and soreness Vaginal rash Thick, white, odor-free vaginal discharge with a cottage cheese appearance Watery vaginal discharge Complicated yeast infection You might have a complicated yeast infection if: You have severe signs and symptoms, such as extensive redness, swelling and itching that leads to tears, cracks or sores You have four or more yeast infections in a year Your infection is caused by a less typical type of fungus You're pregnant You have uncontrolled diabetes Your immune system is weakened because of certain medications or conditions such as HIV infection

yeast-infection

Signs and symptoms of menorrhagia may include: Soaking through one or more sanitary pads or tampons every hour for several consecutive hours Needing to use double sanitary protection to control your menstrual flow Needing to wake up to change sanitary protection during the night Bleeding for longer than a week Passing blood clots larger than a quarter Restricting daily activities due to heavy menstrual flow Symptoms of anemia, such as tiredness, fatigue or shortness of breath

menorrhagia

Inflammatory bowel disease symptoms vary, depending on the severity of inflammation and where it occurs. Symptoms may range from mild to severe. You are likely to have periods of active illness followed by periods of remission. Signs and symptoms that are common to both Crohn's disease and ulcerative colitis include: Diarrhea Fatigue Abdominal pain and cramping Blood in your stool Reduced appetite Unintended weight loss

inflammatory-bowel-disease

Migraine aura symptoms include temporary visual or other disturbances that usually strike before other migraine symptoms — such as intense head pain, nausea, and sensitivity to light and sound. Migraine aura usually occurs within an hour before head pain begins and generally lasts less than 60 minutes. Sometimes migraine aura occurs without headache, especially in people age 50 and older. Visual signs and symptoms Most people who have migraine with aura develop temporary visual signs and symptoms, which tend to start in the center of the field of vision and spread outward. These might include: Blind spots (scotomas), which are sometimes outlined by simple geometric designs Zigzag lines that gradually float across your field of vision Shimmering spots or stars Changes in vision or vision loss Flashes of light Other disturbances Other temporary disturbances sometimes associated with migraine aura include: Numbness, typically felt as tingling in one hand or on one side of your face that may spread slowly along a limb Speech or language difficulty Muscle weakness

migraine-with-aura

The signs and symptoms of polymyalgia rheumatica usually occur on both sides of the body and might include: Aches or pain in your shoulders Aches or pain in your neck, upper arms, buttocks, hips or thighs Stiffness in affected areas, particularly in the morning or after being inactive for a time Limited range of motion in affected areas Pain or stiffness in your wrists, elbows or knees You might also have more-general signs and symptoms, including: Mild fever Fatigue A general feeling of not being well (malaise) Loss of appetite Unintended weight loss Depression

polymyalgia-rheumatica

Anemia signs and symptoms vary depending on the cause and severity of anemia. Depending on the causes of your anemia, you might have no symptoms. Signs and symptoms, if they do occur, might include: Fatigue Weakness Pale or yellowish skin Irregular heartbeats Shortness of breath Dizziness or lightheadedness Chest pain Cold hands and feet Headaches At first, anemia can be so mild that you don't notice it. But symptoms worsen as anemia worsens.

anemia

UTIs don't always cause symptoms. When they do, they may include: UTI A strong urge to urinate that doesn't go away A burning feeling when urinating Urinating often, and passing small amounts of urine Urine that looks cloudy Urine that appears red, bright pink or cola-colored — signs of blood in the urine Strong-smelling urine Pelvic pain, in women — especially in the center of the pelvis and around the area of the pubic bone In older adults, UTIs may be overlooked or mistaken for other conditions. UTI Types of urinary tract infections Each type of UTI may result in more-specific symptoms. The symptoms depend on which part of the urinary tract is affected. UTI Part of urinary tract affected Signs and symptoms Kidneys Back or side pain High fever Shaking and chills Nausea Vomiting Bladder Pelvic pressure Lower belly discomfort Frequent, painful urination Blood in urine Urethra Burning with urination Discharge

urinary-tract-infection

Cystic acne Open pop-up dialog box Close Cystic acne Cystic acne Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Cystic acne Open pop-up dialog box Cystic acne Open pop-up dialog box Open pop-up dialog box Close Cystic acne Cystic acne Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Close Cystic acne Cystic acne Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Close Cystic acne Cystic acne Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Close Close Close Cystic acne Cystic acne Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Cystic acne Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Cystic acne — the most severe form of acne — occurs when oil and dead skin cells build up deep within hair follicles. The resulting rupture within your skin may form boil-like inflammation. Acne signs vary depending on the severity of your condition: Whiteheads (closed plugged pores) Blackheads (open plugged pores) Small red, tender bumps (papules) Pimples (pustules), which are papules with pus at their tips Large, solid, painful lumps under the skin (nodules) Painful, pus-filled lumps under the skin (cystic lesions) Acne usually appears on the face, forehead, chest, upper back and shoulders.

acne

Hairy cell leukemia might not cause symptoms. Sometimes a health care provider finds it by accident during a blood test for another condition. When it causes symptoms, hairy cell leukemia might cause: A feeling of fullness in your belly that may make it uncomfortable to eat more than a little at a time Fatigue Easy bruising Recurring infections Weakness Losing weight without trying

hairy-cell-leukemia

Signs and symptoms of morphea vary depending on the type and stage of the condition. They include: Reddish or purplish oval patches of skin, often on the belly, chest or back Patches that gradually develop a lighter or whitish center Linear patches, especially on the arms or legs and possibly the forehead or scalp A gradual change in the affected skin, which becomes firm, thickened, dry and shiny Morphea affects the skin and underlying tissue and sometimes bone. The condition generally lasts several years and then improves or at times disappears by itself. It may leave scars or areas of darkened or discolored skin. It is possible for morphea to recur.

morphea

Smallpox Open pop-up dialog box Close Smallpox Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. Smallpox Open pop-up dialog box Smallpox Open pop-up dialog box Open pop-up dialog box Close Smallpox Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. Close Smallpox Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. Close Smallpox Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. Close Close Close Smallpox Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. The first symptoms of smallpox usually appear 12 to 14 days after you're exposed to the smallpox virus. However, the virus can be in your body from 7 to 19 days before you look or feel sick. This time is called the incubation period. After the incubation period, sudden flu-like symptoms occur. These include: Fever Muscle aches Headache Severe fatigue Severe back pain Vomiting, sometimes A few days later, flat, red spots appear on the body. They may start in the mouth and on the tongue and then spread to the skin. The face, arms and legs are often affected first, followed by the torso, hands and feet. Within a day or two, many of the spots turn into small blisters filled with clear fluid. Later, the blisters fill with pus. These sores are called pustules. Scabs form 8 to 9 days later and eventually fall off, leaving deep, pitted scars. Smallpox can be spread from person to person when the rash appears and until the scabs fall off.

smallpox

Signs and symptoms of rectal cancer include: A change in bowel habits, such as diarrhea, constipation or more-frequent bowel movements Dark maroon or bright red blood in stool Narrow stool A feeling that your bowel doesn't empty completely Abdominal pain Unexplained weight loss Weakness or fatigue

rectal-cancer

Thyroid gland Open pop-up dialog box Close Thyroid gland Thyroid gland The thyroid gland is located at the base of the neck, just below the Adam's apple. Thyroid gland Open pop-up dialog box Thyroid gland Open pop-up dialog box Open pop-up dialog box Close Thyroid gland Thyroid gland The thyroid gland is located at the base of the neck, just below the Adam's apple. Close Thyroid gland Thyroid gland The thyroid gland is located at the base of the neck, just below the Adam's apple. Close Thyroid gland Thyroid gland The thyroid gland is located at the base of the neck, just below the Adam's apple. Close Close Close Thyroid gland Thyroid gland The thyroid gland is located at the base of the neck, just below the Adam's apple. Thyroid gland The thyroid gland is located at the base of the neck, just below the Adam's apple. The thyroid gland is located at the base of the neck, just below the Adam's apple. Most thyroid cancers don't cause any signs or symptoms early in the disease. As thyroid cancer grows, it may cause: A lump (nodule) that can be felt through the skin on your neck A feeling that close-fitting shirt collars are becoming too tight Changes to your voice, including increasing hoarseness Difficulty swallowing Swollen lymph nodes in your neck Pain in your neck and throat

thyroid-cancer

The symptoms of a coma commonly include: Closed eyes. Depressed brainstem reflexes, such as pupils not responding to light. No responses of limbs except for reflex movements. No response to painful stimuli except for reflex movements. Irregular breathing.

coma