SecA HDX-MS protein flexibility data
This is an example dataset of HDX-MS derived protein flexibility, expressed as Linderström-Lang Gibbs free energies (ΔG/ΔΔG).
The ΔG values obtained using PyHDX (DOI: 10.1021/acs.analchem.1c02155)
There are three protein states, SecA monomer, SecA dimer and SecA with C-tail deletion, each state as apo (ΔG) and ADP-bound (ΔΔG)
More details on SecA dynamics can be found here: A nexus of intrinsic dynamics underlies translocase priming