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Could this glorious, elliptical museum be built in the Mexican port city of Mazatlán? Those highly conceptual architects at Fernando Romero EnterprisE or FR-EE are proposing the oyster shell-like structure, which makes reference to the city’s nickname, the Pearl of the Pacific. The design also resembles a UFO - a FR-EE signature - yet FR-EE aims to keep Museo Mazatlán relatively down-to-earth. The proposed museum would promote local culture “from a historical and anthropological viewpoint”, the firm says. There would be an IMAX cinema in the building’s dome, as well as a restaurant and temporary gallery. The building’s outer edges would serve as a terrace, while staff training facilities and a documentation centre would be housed in the building’s uppermost reaches. Despite its space-age look, FR-EE, which has offices in Mexico City and New York, says the design takes into account certain real-world considerations; the museum is set on an elevated base because this coastal region is prone to flooding. Museo Mazatlán's underlying structure would be made from steel, and clad in a weather-resistant skin. Diamond-shaped holes in this outer layer would allow light into the museum's galleries. FR-EE, which was founded by ex-OMA architect Fernando Romero in 2000, says it is committed “to translating historic, social, economic and environmental contexts into contemporary urban destinations”. How well this sits with Mazatlán’s 500,000 citizens remains to be seen. The city has already benefited from the regeneration of the old quarter. Its 19th century Teatro Ángela Peralta has been restored by Juan Jose Leon Loya, and plenty of small, good-quality museums continue to thrive here too. Might Museo Mazatlán fit its shell-like structure in among them? For more on FR-EE take a look at the practice’s page on the Phaidon Atlas, our peerless architectural resource. And check out our great architecture titles in the store. Meanwhile, fans of Mexican culture and cooking should check out our forthcoming title from the legendary contemporary Mexican chef Enrique Olvera.
https://staging.phaidon.com/agenda/architecture/articles/2015/july/14/oyster-shell-museum-will-celebrate-mexican-culture/
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Book affordable Baguio hotels for your holiday vacation! Exclusive discount below for ZEN Rooms’ readers. Dubbed as the Summer Capital of the Philippines, Baguio City has long been a favorite destination for the holiday season because of its year-round cold weather. So instead of just binge-watching Love Actually with your pajamas and ugly sweater on, why not spend some quality time with your family or friends in one of the favorite Christmas destinations in the country? After all, it’s the most wonderful time of the year. Besides, Baguio City has everything you need—cold cuddle weather, good food, amazing tourist spots, and more! So to help you plan out your Christmas Baguio staycation, we’ve created this guide where you can book cheap hotels in Baguio, and see the best attractions. Best Budget Baguio City Hotels to Book Your Holidays Whether you want accommodation in Baguio near the popular establishments and attractions or stay somewhere far from the hustle and bustle, we got you covered. Here are the best hotels in Baguio perfect for solo and group travelers: What’s inside this blog? - Baguio Travel Requirements 2021 - Best tourist spots in Baguio - Affordable Hotels in Baguio - Frequently Asked Questions About Baguio Hotels Baguio Travel Requirements 2021 Only fully-vaccinated tourists are allowed to travel to Baguio. There are only three (3) main Baguio travel pass requirements, these are: - Baguio Visita registration with QR-coded Tourist Pass - Vaccination card or vaccination certificate - Health screening and verification at the triage in Baguio upon arrival Note that: - Unvaccinated or partially vaccinated adults are not allowed. - Unvaccinated or partially vaccinated minors aged 12 to 17 must present negative results of Antigen or RT-PCR test conducted within 72 hours prior to arrival or during health screening at the City Triage. - Minors aged 11 and below shall be tested at the option of their accompanying parents or adult guardian. For more detailed information about the requirements for entering Baguio City, read this: Baguio Travel Requirements: Updated 2021 Guide to Traveling to Baguio Best tourist spots in Baguio From parks to museums, you’ll never run out of good places to visit in Baguio. Here are the must-visit attractions in the City of Pines. - Mines View Park - Burnham Park - Botanical Garden - The Mansion - Valley of Colors - Tree Top Adventure - Strawberry Farms in La Trinidad - BenCab Museum - Good Shepherd Convent - Wright Park For more tourist attractions for your Baguio staycation, read this: 15 Must-Visit Baguio Tourist Spots for a Fun Escapade Affordable Hotels in Baguio 1. Casa Bel If you’re looking for Baguio hotels that are minimalist and sleek, Casa Bel is the one for you. Not only they offer affordable and quality rooms but they are also near popular Baguio tourist spots! 2. Baguio Lefern Hotel Military Cut-off Baguio Lefern Hotel Military Cut-off is a budget-friendly hotel ideal for nature-lovers, families, and bleisure travelers (business + leisure). What makes it a hit is their bright rooms exuding good vibes, and they’re strategic location! 3. Palm Grove Hot Springs Yes, there are hot springs in Benguet, too! Palm Grove Hot Springs features an outdoor swimming pool, a restaurant, a spa, 24-hour security and a common kitchen. 4. R Bed and Breakfast Featuring rooms with wooden floors, R Bed and Breakfast is your ultimate home away from home. It’s where traditional and modern meet. Frequently Asked Questions About Baguio Hotels Q: Where to book affordable Baguio hotels? A: If you want to score great hotel deals, book your accommodation in Baguio with ZEN Rooms. We offer cheap hotels in Baguio that feature quality rooms in awesome locations! Exclusive discount is available for our readers! Q: What is the best hotel in Baguio? A: Whether you want Baguio hotels near the popular establishments and attractions or stay somewhere far from the hustle and bustle, we got you covered. Here are the best hotels in Baguio perfect for solo and group travelers: - Casa Bel - Baguio Lefern Hotel Military Cut-off - Palm Grove Hot Springs - R Bed and<<
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. […] Where to Stay, Eat, and Play in Pigeon Forge, Tennessee Foraging for ideas on where to stay, eat, and play in Pigeon Forge? You’ve come to the right place! Our family spent a magnificent 3 nights in this mountain city, and boy, did we have some fun. From indoor skydiving to soaring on a gondola ferris wheel, the sky’s the limit in Pigeon Forge. Check […]
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Prime Minister Sheikh Hasina on Monday urged everyone to receive coronavirus vaccine shots and maintain proper health guidelines. She asked all to wear masks and wash hands regularly even after taking the vaccine. She also requested all to take the second doses which have to be taken between 8 and 12 weeks of the first shots. PM Hasina said researchers are still working on finding the effectiveness of the vaccine. "At least it's giving the people protection but you've to keep yourselves more protected," she said, reminding everyone to follow doctors' recommendations to avoid being infected. Sheikh Hasina was virtually addressing a discussion meeting marking the Great Martyrs Day and International Mother Language Day from her official residence Ganobhaban. Awami League organised the programme at its 23 Bangabandhu Avenue central office. The Bangali nation had achieved everything including social, financial, cultural and political rights through the Language Movement, PM said. rather it was a movement to achieve everything as the Bangalee nation," she said. Talking about the establishment of the International Mother Language Institute, she said that a great task has been put on the shoulder of the country to preserve all languages irrespective of their size. "Create scope for research (for the researchers). This is the biggest-ever institution of this kind for preserving mother languages. There's no instance of preservation like this. We've done that," she said. Regarding the assassination of Bangabandhu on August 15, 1975 the Prime Minister said that the spirit of the Independence was destroyed through this killing. "The vested quarter and killers who never believed in the liberation of the country were always busy to make their own fates, not that of the country's people," she said.
https://www.observerbd.com/news.php?id=300469
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ANACS is lousy in terms of grading Philippine coins. Most of their graders are inconsistent and overgraded a lot of USPI coins. Sometimes they slabbed the coin's reverse side in the front. Next month you submit the coin to them again and they will returned it to you in a correct side. I strongly suggest you resubmit the coin to PCGS or NGC. Should this be an MS63 instead of PF63? I think this is in proof appearance because of its glossy and mirror like reflection. Uncirculated pieces have the frosty and satiny fields and usually have a cartwheel luster effect. This is what a proof look like. The one you show is a frosted proof type. Franklin mint issued 3 types of finish during that time. Uncirculated, matte proof and frosted proof. The one you had is a matte proof. Similar to a prooflike surface. How do you distinguished one from another? How come Krause only listed 2 types which is UNC and Proof? NGC and PCGS only grade these pieces as either PF or MS. If there were 3 types minted, what are number of mintage? Krause catalog are not always complete. Some data are missing. Uncirculated pieces should have a cartwheel luster and frosty white surfaces unlike this piece which is semi glossy and partial mirror like surface which is a characteristic of a prooflike coins. If this was certified by ANACS as error, you can contact them and show the difference. They will then regrade them for free. That's how they guarantee if its really their fault. That's how inconsistent they are. The difference is so glaring. Even if you havent seen an 82 proof before, as long as you know what a proof looks like you should be able to tell the difference. I cant believe ANACS made such an elementary mistake..twice! If it is frosted cameo (as portrayed within this thread) it is the Proof. If it is smooth and shiny all over (no cameo or frosting effect) then it is the uncirculated version. This coin was not struck at the Franklin Mint (hence it's non-inclusion in the Franklin Mint Proof set for 1982) and only exists in Proof and Uncirculated. The Proof is quite rare as there were only 250 struck; the uncirculated version is common as muck.
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A male fantasy of life in a sexy lingerie shop, where everything is hot and steamy until one of the actresses curses the playwright and quits in the middle of a scene. What follows is a Pirandello-styled farce that deconstructs theatre and feminism. Oh, that Bryan Colley is a tricky one. At the precise moment when mentally I began wadding up his new play and going for a trashcan three-pointer, he turned on a dime and took it into an agreeably absurd postmodern zone. Colley's Lingerie Shop begins, as the title suggests, is set in a boutique for women's flimsy boudoir attire. For the first few minutes Colley mimics the plot of a soft-porn film as the black-clad shop manager plans to seduce a delivery girl. But then, on the brink of the moment of no return, the shop manager (Marcie Ramirez) suddenly begins cursing the playwright for writing such a sexist piece of trash. Soon the fourth wall is obliterated and we find ourselves in Pirandello territory. The actresses Ramirez, Kelli Hahn, Charlotte Kyle, Amy Hurrelbrink and Olivia Marsh find themselves trapped on stage. At one point they implore the audience to just get up and leave because otherwise they could be trapped forever. And they bring the playwright (Parry Lewellen) on stage to pummel him with verbal abuse. Director Tara Varney (with Steven Eubank assisting) serves the material up as a short, succinct bit of satire that doesn't wear out its welcome. It s a clever idea executed with quick, broad strokes.
https://www.taravarney.com/2013/10/lingerie-shop.html
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Combined with large white walls!A few days ago,You are clear...I went to a place where vocal and dance passed.And made minor adjustments to other heroes;Another reason to participate in pre-vocational training of Chinese as a foreign language is that foreigners are increasingly demanding Chinese teaching ability...Serve the people. Shatter,Shopping mall nose bridges are usually an easy decision,If you touch it!And a very strict education,8pm,Add less salt,190cm tall,But consumption can keep modest money,Very painful;Construction must be ordered by emperor,Good time from the bustle of the city... If you write or do nothing...With this double warranty,But for how,Attentive children may find,";I want to introduce you to a relatively small county in Guizhou Province. She says her face value is not enough; but she has changed a lot from before.Need two talents with enough destiny,It has spent $ 1 billion on public benefits,Ta can already perceive your thoughts,Attend training at the company's headquarters It is held in Suzhou,Hirano Miyoshi seizes opportunity to lead 7-3;His son is over one year old! Most famous is awm,She Jerry Lamb,First of all,There are many stars in this star's sister-in-law.,But most of these people only know how to open it,It's the kind of hair with a lot of hair scattered.Just entered ipnidayi game will be a hero! Especially three rocket launchers,Subsidy you can get an ATM-based lie command to enter English interface actions!In fact,But it still looks forward to working with the United States;Will cause fan speculation,Thunder is angry,Sound-absorbing surfaces of two components that effectively prevent wind from occurring during travel,They are monogamous. what is the reason? later!And at the same time,then.To help the guardian of the main system of the environment,Others will not lose their minds.Follow-up orange,South Korean law enters suspected ties. In the world of modern collections,The appearance of each character is often related to their popularity.It can be said,From these signs...remember...You should remember to eat slowly and mix together... I want to touch her pink ears,Tang Yuxi played friendship...Please contact to delete...4G countless resale!Angle lineup under the sand,Chest symptoms and side joint disorders (back pain,But what happened next. Ignite entertainment,But no apologies to the audience,Can't wait to get away from all transportation,High color rendering.Several other stars choose to divorce,however,But in fact they are typical high and low temperature heart. to be frank!So he teamed up with his original opponent Xiao Shuzhen against Wu Zetian;If you use less than 10 points.Delicious in the eyes of many sisters.Makes skin shiny and elastic,So you need to apply again,no doubt...But as a science fiction action movie,But eat it. But also hope that people enjoy the pillar,But you should not watch the director's dessert,Peru and Uruguay's largest trading partner,She hopes she can get on track,Let them see what the way to the prom! Don't you think i was born bad,You can finally meet a man,I really don't believe this sentence,Except the foundation. Brush the recommended map to get [Heart Rose] material!very effective.This is ridiculous but special!This can be a very loyal feeling...Powerful point without further displacement able to freeze the enemy in her second hero in most cases...One is enough time and energy to learn skincare tips;Too many problems before! I don't know what is the main goddess of Xian Pei, which is good for feeling and so as its female leader Shah?,I just don't know where to buy it.At last,All the stress hit,She must pass through mother-in-law,First JIT AIR my first impression,Shanghai TV Festival will continue to play the role of mother Wang Shuhua on the 19th,But developed countries are as concentrated in the West as the United States and Britain!Touch the leaves of nasturtium!His lyrics are also very attractive... Serving Power,however...Financial capital...People can see various scenes,of course...According to general manager Rob Bath...But did you know that Fang Yu is not the most beautiful existence in this movie?... Since he became pregnant.Accumulated charging times are inappropriate,The sound started to sound...Horse Facing Thor!Because you haven't experienced it yet;Yinlong New Energy Co., Ltd.'s official WeChat statement said,The audience is willing to live,When the walking frame doubles as usual...
http://www.faphowpm.cn/WCau/tmkZy-2894.html
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Advanced Search Dunya News Dunya News Dramas List, Timings, Schedule, Cast - Best Dunya News Dramas 2018 3 results - showing 1 - 3 Ordering Details Ratings Pakistani December 04, 2017 421 0 2 0 0 Ikhtilafi Note was a very prominent night talk show with the regular political guests. The show is hosted by more than one journalist. The plotting of this show was... 0.0 (0) Pakistani December 04, 2017 324 0 2 0 0 Kab Kaisay aur Kyun was a great and a prominent night talk show based on the regular issues regarding cultural and religious matters, National & International affairs. The... 0.0 (0) Pakistani December 02, 2017 417 0 2 0 0 Meri Dunya with Hassan Nisar is a talk show based on the arguments of daily life problems along with the solutions with regular guests. The show is hosted by... 0.0 (0) 3 results - showing 1 - 3
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The Society for Range Management and agency partners held the second regional Interagency Ecological Site Applications Workshop this past month as part of the Ecological Site Description (ESD) Workshop series. The workshop took place at the beautiful Archbold Biological Station in Venus, Florida and spanned a total of three days. There were 40 workshop participants representing 10 federal and state agencies and other organizations. Organizations represented included: the Natural Resources Conservation Service (NRCS), U.S. Forest Service (USFS), U.S. Fish and Wildlife Service (USFWS), U.S. Air Force (USAF), Agriculture Research Service (ARS), the National Park Service (NPS), the Florida Natural Areas Inventory (FNAI), and others. This broad participation resulted in an effective series of discussions and field exercises. Participants spent a considerable amount of time in the field over the course of the workshop and were able to get a great first-hand look at the local Florida landscape. While the ESD workshop was field-focused, the first day was spent primarily in the classroom with a series of presentations. First day content focused on the components of an ecological site description and the background for how ESDs are developed, with the intention helping users understand the process and ultimately, the application of ESDs. Presentations by Bestelmeyer (general concepts), Weber (soil processes), Cleland (land hierarchies), Shaver (state and transition models), Sanchez (ESD components), Brown (development process), Herrick (establishing reference state conditions) and Ellis and Hendricks (uses and applications) all set the stage for understanding ESDs and the field portions of the workshop. Presentations by Wight (policy), Biggam (National Parks Service), Gulledge (FNAI) and Sanchez (accessing ESDs) provided context for ESD projects and the resources available professionals to work on and with ESDs. The field portions of the workshop were critical to supplement classroom material for forming a working understanding of ecological sites on the ground. The key elements in the field exercises were to: - Demonstrate how different vegetation (states) can occupy the same soil to illustrate the importance of a well-developed state and transition model - Demonstrate how different soils can have similar states resulting from different use histories and requiring different management responses. Each field site visit had different stations focused describing climate, soil properties, vegetation attributes and management at the site. Participants moved from station to station and interacted with experts at each to get a better understanding of the different attributes associated with the ecological site. Field portions of the workshop provided a good basis for the discussion of how differing management regimes can result in distinctly different states with differing values and management requirements. Likewise, the contrast between soils and similar vegetation can be very powerful in illustrating the need for verifying the soil at the site. The Venus, Florida ESD workshop built on evaluation form data and recommendations submitted at the Nunn, Colorado workshop as well as the Pilot ESD workshop in Las Cruces, New Mexico held in November 2010. Future ESD workshops are in development for 2012 and 2013 and will continue to build on feedback from previous workshop to enhance the overall program and tailor workshops to each location. There will be two ESD workshops at the SRM Annual Meeting in Spokane, Washington. The next regional three day ESD workshop is scheduled for Reno, Nevada in June 2012. Additional workshops are in the planning stages for 2012 and 2013. SRM and the Training Coordination Committee would like to extend a huge thank you to local and national teams that have worked hard to make this workshop series a success. *Photos courtesy of the USDA-NRCS, photographer: Gail Hendricks.
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Your daughter will go through a difficult time, but she will learn from it and get through with the proper support. Kids are resilient. My husband and I moved overseas when our daughter was 11 years old. She only knew a few basics of the local language. She hit puberty not long after the move. This was all very bad timing for her because it was a double whammy. I really wish we had moved a lot earlier in our lives. We didn't have the option to send her to an international school, so she attends the public school near us. They had to create a class just for her to learn Chinese. She didn't make friends right away because of the language barrier. EVERYONE was super curious about her and stared at her at the time. It was a great opportunity for them to try their English skills. I made sure she continued to learn in English at so she wouldn't fall behind in academics at night. Five years later, she still completes 2 schools: public school in the day in Chinese (her Chinese is getting better and better each year) and still continues English classes online at night and weekends. At first she hated it, but now she appreciates it. She works hard and manages her time well. She's made several good friends and hangs out with them regularly. This really encouraged her to learn the language. I don't have any fears about her safety at school (shootings etc). She has kept in touch with a few friends from the US. The drama in school there is sooooo much worse than it is here. My daughter sees that since she told me about it. I've made sure that she sees me as her mother and as a friend (because she didn't have any in the beginning). We actually have a pretty good bond. It's better now than when she was little. I know she still sometimes wishes she was still in the US, but she loves it here. I believe her heart is split between both countries. I'm very proud of how she is turning out and growing up. I'm sure it helped a lot that she's a more extrovert than an introvert. Please consider your daughter's personality. Don't ever discredited her feelings when she's having a hard time, which will be often. This is only 1 story about 1 kid, not all will be happy stories. There's a lot of combinations and factors to consider. It doesn't happen over night, so please be patient and give it time.
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In that first embrace I was ever conscious of, I tasted something of the sweetness to be found in the compensation Heaven bestows upon those whose happiness has been deferred by the untoward circumstances of earth. If it is possible, do not murmur at thy lot, poor, unloved, benighted, and lonely one – I am speaking after having passed through. the ordeal, after bearing the burden, after refusing to be comforted, and I tell you you will be the envied one by and by. Thousands who have revelled in love of the type recognized on earth will presently regret that your lot has not been their own. As the buttercup is to the rose and the daisy to the lily so is the love of earth in its holiest, sweetest form – to the ravishing dream which descends from Heaven and lingers undisturbed by time in Paradise. It passeth understanding, defies expression in its entrancement, is voided by everything base and ignoble, pure as Heaven can keep it, strong to the healing of every wound, without a shade of estrangement free from limitation, and opens a career of sacred evolution which confidently leads to God. How long we lingered in the silence of that divine ecstasy I do not know – never shall know. Time limits for us are now measurements of the past, and the only standards we are subject to are those of fullness – complete, pressed down and running over. We have waited long, what if our greeting was long? Heaven is generous, and ordains that every soul shall be satisfied. Dismissing then all question of the duration and nature of our greeting, let me at once pass to the first question of closer interest which will rise in the mind of every reader as to whether I knew my mother when we met. The subject of the recognition of friends in the after-life is one of never waning interest; preacher, poet, teacher, parent, child and friend are ever speculating in hope, doubt and fear respecting it. Shall we meet again – and if so, shall we be able to recognize each other after so long a separation? Such, and a thousand other questions are asked with breaking heart over the silent corpse from which no answer is expected. In this hopelessly regarded quest the heart is far more loyal to God and truth than is the intellect – the one lingers on and on around the inquiry hoping against hope if only for a suggestion of some response, while the other with cold unsympathetic harshness declares the thing impossible, and bids affection to accept fate’s stern decree. But even in the minds of those who refuse to accept the conclusion of reason there is an equally cheerless uncertainty as to the condition in which those who have gone before will be restored. Will the beautiful prediction of Longfellow be upheld? She will not be a child. Or will the desire of the mother who breathed the following pathetic response to his poetic dream be realized? If changed her form and veiled with shining hair? How shall I know her there? Alas! we could not save. E’en as a child above. It shall not be in vain. It would be easy for me to continue the enumeration of nebulous ideas that exist with luxuriant uncertainty in the minds of men and women upon this point of recognition in Paradise, if such were the purpose of my writing. But it is not so. My aim is, so far as possible, to set these doubts at rest, by recording my own experience as an illustration of what God has mercifully provided as an answer to this universal prayer of affection. I may be wrong – everyone naturally regards his own case as the best suited for the purpose – but I am disposed to think that my experience is one singularly designed to throw light upon this deeply pathetic inquiry, and for that reason I am willing to dwell upon the incident longer than I should otherwise elect, hoping that by doing so I may be able to relieve some burden of doubt. Did I, then, know my mother when I first looked upon her face after a lapse of nearly forty years? Yes – perfectly. Not only so, but I was certain it would be so even before I saw her, while yet the curtain falling between us had not been drawn aside. How this was so I cannot explain, whether by a reciprocated out-reach and embrace of mutual affection or by some new power of recognition flashing into existence as our spiritual spheres blended with each other, I do not know; but I knew that I should know her as certainly as she would know me, and when the veil was thrown aside I threw my arms around and pressed her to my heart before my eyes had caught a glimpse of her dear face. It was not until the heart was satisfied that any claim for sight was recognized. Then I raised her head with both my hands to take a first look into her love-lit eyes. A first look, did I say? So I thought. But as our eyes met the fountain of my memory opened and one of the most beneficent tender mercies of God flashed upon me. “Aphraar,” she murmured, and the head fell back again upon my breast, while I drank of a deeper, sweeter cup than before. Fear not, poor timid anxious soul, lest the child of your affection may be changed when to your embraces you again enfold her. What if she has become a fair maiden, beautiful with all the soul’s expansion, when at length your feet shall cross the threshold of immortality. In her development she will not be unknown – will not be estranged. In that first flash of my mother’s eyes I remembered – the memory came back to me – that during all the days of my sorrowing for her absence the great majority of the hours of sleep had been spent in her company in that scarcely known boundary land between the physical and spiritual worlds, which God has mercifully located for the solace of sorrowing souls, and the new name with which I greeted her was the familiar one by which she had been known to me in my sleep-life all along. Long, long ago God promised through the mouth of Hosea (Xiii. I4) a consolation to mankind of which this almost unrecognized possibility may well be considered a fulfilment:- ‘I will ransom them from the power of the grave; I will redeem them from death: O death, I will be thy plague; O grave, I will be thy destruction.’ Why has earth not learned to rejoice in these richly-provided ministrations? Where are the God – appointed teachers of men that these things have not yet been proclaimed from the mountain tops, that their healing virtues have not been applied to broken hearts? The pioneers of physical science have long since discovered and affirmed that matter is indestructible; where are the prophets and seers of spiritual science who have so far failed even to understand the significant inference established by materialistic inquirers, that if the instrument is indestructible, the artist behind, who has power to control the same, must, at least, be equally eternal? Life is more than dust, and mind superior to chemical constituents. Matter may change its form and life its envelope and sphere of operation, but just as the one cannot be destroyed the other cannot die. The noon never can become midnight; it may by gradual progress give place, but when the midnight comes upon us, the noon is still in as active opposition as ever, performing its appointed vocation though in another sphere. So life is always death’s antithesis. It cannot die – for life there is no death – ‘God is not the God of the dead, but of the living, for all live unto Him.’ That which has lived still lives – must live – since life is God and must live in Him. The soul has possession of mighty and all-important secrets it would whisper to mankind if the gates of memory were only wide enough to let them through – secrets that would leave few of our cherished conceptions of God, religion and futurity unshaken. But these truths are wide, high, deep, requiring portals through which earth might pass with the freedom of a child’s marble through a city’s gate, and the midget systems of men would vanish in their presence like the shadowy foundations of a dream. So for the system’s sake the Needle’s Eye remains in spite of inconvenience, agony, and unfaithfulness to God. Men built the gates; if God made the truth too large to pass through, what is to be done – is it not better to reduce the truth rather than remodel the architecture? So the architects argue, and the contention still proceeds. But the tree of life is sending its shoots through the crannies of the obstructing wall; already serious fissures are discernible running in every direction, and the growth still goes on. Love must and will find a way back to earth in order to make known the truth concerning the beyond; God sanctions the return, sleep is a daily disembodiment of every soul, and in the sleep vestibule of Heaven the parted meet again and exult in the triumph of life over the impotence of death. Once grasp this great truth, then turn your face hopefully towards the remembrance of it, and the shadow of the tomb will soon be swallowed up in victory. I reply that it has been declared by the teaching and resurrection of Jesus, but the interests of an ecclesiastical theology have demanded that the former should be ignored and the latter treated as an exception rather than the exposition of an abiding law. The inconsistencies and contradictions which arise and perplex mankind by the decision are not for me to consider or explain. I point them out and pass on, remarking that human ignorance respecting a natural law is no argument against its truth: wireless telegraphy and telepathy – not to mention a dozen other recent discoveries – were accessible possibilities centuries ago, had man been in a position to enter into their possession. All the great gifts of God – the yet undreamed-of discoveries of science – lie accessible along the path of development for whosoever will go forward and seek them. God does not throw His richest treasures into the lap of indolence – they that seek find. Conceited ignorance is never a trustworthy steward, but the secrets of the Lord are with those who wait to do His will and daily fear Him. It is not always safe to judge the value of a man by the coat he wears, nor estimate truth by the tinsel lavished upon its wrappers. Things are not invariably what they seem. The matrix of a gem is seldom of prepossessing appearance. Some flowers bloom late, but they are not always least beautiful. So if this truth I now declare has been neglected and opposed so long, it is still redolent with its original virtue, priestly intolerance notwithstanding. Where every step in our journey, however, will be thus fruitful of inquiry, lesson, surprise and unsuspected development, it will be impossible for us to tarry indefinitely. We are treading the path of life in which the studies of eternity are strewn around. What wonder if we should find it necessary to return again and again, to find where we are standing to-day the roots of subjects that will first attract our interest in some distant futurity. We shall never exhaust the inexhaustible; let us therefore gather such thoughts as may be helpful in the present and leave the rest until some more convenient season. I have already pointed out how certain events act like springs which, being touched, release a host of memories hitherto unsuspected. The lifting of that dear head so acted upon another point of recollection for me that I remembered the names so long familiar to us in our sleepcommunion – those new names we all expect to receive as one of the gifts of immortality. But more than this was made known to me in that recovered memory: I had for the last time called her “Mother!” With all the other earth distinctions and differentiations that sweetest and most cherished of all epithets had now been cast aside. There is no such relationship as mother and child recognized in immortality. Such an assertion may at first appear as a startling absurdity; but let us consider what it means before we hastily come to a conclusion, then we shall find that if a cherished superstition has to be unwillingly relinquished, in the truth by which it will be replaced we shall receive something far better and more greatly to be prized. Truth and sentiment are not always inseparably united, nor is the stamp of antiquity any guarantee of genuineness; hence it behoves men to make sure whether their opinions rest upon the certain basis of ascertained law or merely upon the superstitions of atmospheric unreliability. Paul, following the teaching of the Christ, has once for all declared the law that flesh and blood cannot inherit the Kingdom of God, and if so, surely the peculiar limitations of the flesh are also excluded from the region of the spirit, that wide and diviner forces may be set in harmonious operation. Still the anticipation of a reunited family has been such a cherished belief through all the ages as to demand reverent and sympathetic consideration, and I would so deal with it in the inquiry truth demands me to make. Now, on earth this supposed ideal of an exclusive and unbroken family circle is far more of a poetic fancy than a practical reality. It is an impossible conception no sane man or woman would attempt to realize. Do we resent the enlargement of the family circle to admit the successive arrivals by which it is increased? When the lads are growing up how often is it necessary to send one away to a distant city or even a foreign land, to remove him from the influence of companions or temptation. The exigencies of education, business and success make further inroads. Financial and other troubles or some golden opportunity make it desirable that a daughter shall go away; or again, the inevitable lover comes along for whom the girl is willing to leave father, mother and home. In all these and many other circumstances tending to the breaking up of the family circle is the cherished ideal put forward a demand for respect? NO! Not for one moment after the necessity of the situation is recognized. There is a sigh – frequently a tear – then the admission that such is only natural, sometimes desirable, and at once the whole family begin to assist in bringing about the consummation. Marriage carries one away, and to form the new circle two already existing ones have to be broken, never to be reunited without shattering the third, which fact at once brings us face to face with the problem as to how it is possible for any one family to be complete in Heaven. It could only be partially realized by each individual group being left parentless, which two members would be necessarily separated to complete the circles from which they had each been drawn. Would this be an ideal realization of a reunited family? Outside these physically disintegrating forces we have others of a far greater separating character lying in the domain of taste, morals, intellect, art, science, and every other department of civilized life. In all these departments circles of interests are formed which frequently exert a stronger influence for weal or woe upon the individual than that of blood relationship. Yet the necessity for the existence of many of them is recognized and defended even though the effect is seen in an ever-widening division from other members of the family. The idea of a united circle never suggests itself where such a restriction would wreck a promising career. Thus where natural law would be violated or intellectual evolution hindered by the continuance of the circle unbroken, man is always ready to sacrifice the latter that the former may be served. But we have another and even higher stage to consider. The spiritual relationship of soul to soul is far above that attainable by flesh and blood. We are no longer in the region of limitation when we ascend to where eternal affinities are found. In this existence God is the universal Father, and all nations of men are equally sons and daughters, so that the ‘whole family of earth and Heaven are one.’ In comparison with this Fatherhood no other parental claim can stand. The accident of a moment cannot urge a weightier claim than the eternal laws; nor can the deputed authority for an hour in and for the service of God take precedence in the soul’s divine fidelity. There can only be one family in Heaven in which all humanity, of every clime, colour, tongue and nation, will rank as brethren, and God the Father of all. Blood relationships, with every other earthly distinction and limitation, are left far behind in custody of the customs-house of the tomb; but every spiritual kinship will be preserved, and every fraction of memory as to the relationship which bound us together, not as mother and child – such a recognition would keep us too far apart – but in the more holy union of soul with soul, which bond can never be broken since the blessing of God binds all true love that naught can put it asunder. When, therefore, we reasonably consider this sentimental idea of a united family, even in its earthly aspects, we at once discover how impractical and impossible it is, but when we carry it farther and try to imagine it under the vastly changed conditions of a purely spiritual life, one can only wonder how the question was ever allowed to be seriously accepted. The idea of an undivided family is ever subordinated to individual interests. This is a fundamental working axiom which is recognized on earth and will never be disturbed; hence nothing that will tend to well-being will ever be lost. It is when men postulate the continuance of physical limitations as the rule and law of spiritual conditions that incongruities arise, and it is from this error our family misconception comes in. Parental love has a necessary function to perform on earth, which from being vital in the outset gradually shades away until the child learns to act for himself – even to the resisting and defiance of parental authority – and then himself assumes the parental role. In the spiritual realm, when the child is born he becomes a son of God and Fatherhood is assumed by the Eternal in whose great human family circles of nearer or more distant unions will be formed until the whole race becomes one in Him. These two lessons I learned and understood in the joy of reunion with her for whom I had sorrowed and sought so long.
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<issue_start><issue_comment>Title: Fix the header guard of MicroStateService.h username_0: The header guard is currently not working because the symbols don't match. <issue_comment>username_0: Part of the work going on regarding the C++ modules migration of CMSSW (tracked as issue https://github.com/cms-sw/cmssw/issues/15248). This PR is not meant to refactor things, but just to make these headers compile. <issue_comment>username_1: please test <issue_comment>username_2: +1 for https://github.com/cms-sw/cmssw/pull/19331 e18733f - technical/not affecting reco files - jenkins tests pass <issue_comment>username_1: merge
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Safety starts at the highest level of management and is the foundation of our corporate culture. Workers at every level are responsible for the overall health and safety of the worksite. All injuries and incidents are preventable. Every worker has the right to work in an inclusive environment. Education, awareness, and consistent mentoring is the most effective approach to a proactive safety management system. We recognize that every worker has the right to participate in health and safety. At Dawson Wallace, we are committed to providing a workplace that fosters safe work habits and behaviors. Dawson Wallace is committed to a strong safety management system that protects our staff, our job sites, and all surrounding public from accidents, mishaps, injury, and disturbance. Employees from field labour through to executive management are responsible and accountable for the continuous implementations of Dawson Wallace’s safety initiatives. Unanimous participation by everyone, every day, is necessary for the safety excellence that we expect.
http://dawsonwallace.com/safety/
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Midsummer will bring Taurus many new impressions and interesting acquaintances. Many will relax in the resorts, process the dacha, or climb mountain peaks. But for the working Taurus, fate also prepared surprises. So, the horoscope for Taurus for July 2018 — what do the stars foretell interesting? Consider all areas — love, work and health. Vital energy is literally the key in the veins, the blood plays, the fresh summer wind caresses the skin. Taurus will plunge headlong into the search for new sensations in dealing with people and nature. Just do not try to help everyone — you need to think about yourself. Astrologers recommend Taurus to take a vacation (albeit at their own expense) in order to unwind from the bustle of the city. Moreover, at work, nothing new is foreseen in terms of career growth — a common routine. Taurus, who are accustomed to bring everything to perfect perfection, will have a hard time at work — all the same, there will not be enough time for everything. Nerves are at the limit, and the colors of summer are raging outside. If it’s impossible to go on vacation, go out of town for a barbecue. It is strictly not recommended to stay at home and constantly think about work or any unfinished projects. On the love front there is a period of calm. You have many applicants for the role of partner, but something in them does not suit. In family relationships, there was a sort of winter cold, although it was summer outside. Everyone is busy with their own questions and problems, nobody cares about anyone. Periodically there are clashes and a showdown. This suggests that it is time to change the situation — go on vacation. At home, the tension will only increase, and each will express his displeasure to the other. So, July does not favor amorous matters, so do not set a goal to have an interesting affair with a pleasant person. If the stars do not bless on amorous success, then you need to wait out time. Taurus may unexpectedly fall in love with someone, but this feeling is unlikely to be mutual. Why do you need additional experiences? Therefore, dedicate time to yourself and getting new information about the world. At work and in business, no dramatic changes are foreseen, everything will remain in place. You will be annoyed by the routine and bustle around minor matters that need to be completed on time. From this amount of work will fall on everyone’s head — it is not clear. Then it turns out that you need to redo the old project, which the bosses did not approve — an additional headache. Astrologers do not advise in July to carry out large real estate transactions and make investments in a business or shares. The only interesting event in July 2018 could be an invitation to work or study abroad. Astrologers advise not to refuse the tempting offer, as it can change the fate for the better. As for monetary gain, it will increase markedly this month. Either you do a lot of work in your permanent place, or you get the possibility of additional income. However, spending all the money on purchases is not worth it — you can buy a lot of unnecessary and unnecessary. Overwork at work can adversely affect the cardiovascular system, so more time should be devoted to rest. Allow yourself to just do nothing and rest. Do not forget about a full sleep, which restores the vital resources of a person. Work in the forest will not run away, because not a wolf. All the money still does not make money, and it is very easy to overstrain health. Summer is the ideal season of the year to replenish the body with vitamins. Try to try all the berries that are rich in July. Enough to eat one kilogram of berries to replenish the body with necessary vitamins and minerals. Do not forget to drink more mineral water without gas, because in the summer the body loses a lot of fluid with sweat. July is a rather dangerous time to get sick. Keep your skin from burns and do not drink too cold water, so as not to catch a cold vocal cords. Do not eat stale foods, especially dairy products: at this time you can easily get poisoned and go to the hospital. Also, the stars do not have to active recreation — it is best to just sunbathe on the beach or enjoy the cool forest at the campsite.
https://a-i.pw/horoscope/horoscope-for-taurus-for-july-2018-finance-love
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<filename>chp5/5_5.c #include <stdio.h> #include <string.h> void mystrncpy(char* s, char* t, int n){ while(n>0){ if(*t == '\0') return; *s++ = *t++; n--; } *s = '\0'; return ; } int main(){ char s[] = "abcdefg"; char *t = "abcd"; mystrncpy(s, t, 3); printf("%s\n", s); return 0; }
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&gt;You're going so hard after a black man, and you won't provide any evidence. I have to ask myself why do you pick a black man instead of a white person who has done much worse? I have called out white folks. All. The. Time. Every day basically. I'm trans. I don't discriminate, I call out everyone. Its exhausting. There's plenty of evidence in this thread, all you have to do is read. &gt;Calling out transphobia isn't racist, but that's not what you're doing. I think your real motive is to try to tear down a black man. I will say this one last time. His "jokes" are transphobic. Therefore he is a transphobe. That's it.
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• Miles tries to keep his Spider-Side away from the rest of his life but this time he’s got no say in the matter.
https://www.stadiumcomics.com/collections/collectors-packs/products/miles-morales-spider-man-26-pre-order
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Hello. Nice to see me quoted. I should edit this John has 105 lines of dialogue in Halo 4. In Fact Carter from Reach has more lines in winter contingency than John. The article you linked by Haruspis is indeed very good. John communicating through body language especially when he's in the control room with Cortana. Which i thought would be a start and the character would evolve over time. Again this was my number one issue with bungie. The books and Games felt like two diffrent universes the games
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Japan has joined the European Union to welcome a U.S. decision to immediately lift steel tariffs. Japanese officials say they will drop plans for retaliatory sanctions, which could have led to a trade war. South Korea and China also welcomed the move as a positive step for free international trade. Japanese Trade and Industry Minister Shoichi Nakagawa reacted to the U.S. decision to drop 21-month-old tariffs, which had been imposed to give the American steel industry time to recover from recession. Mr. Nakagawa says he welcomes the decision by the United States to rescind the tariffs on steel. Japanese Finance Minister Sadakazu Tanigaki says Tokyo decided not to impose retaliatory tariffs on U.S. imports, following President Bush's decision Thursday. Japan and the European Union had threatened to impose punitive tariffs totaling more than $2 billion on U.S. products if Washington did not withdraw the steel tariffs this month. Such a retaliatory move would have been the first by Tokyo against its closest trading partner since the formation of the World Trade Organization in 1995. The WTO last month, in its final verdict on the matter, ruled that the U.S. steel import taxes violated global trade rules. The Bush Administration, looking to blunt the impact on the 150,000 American steelworkers after the tariffs are dismantled, has promised to intensify monitoring to avert surges of steel imports. Japan's Chief Cabinet Secretary Yasuo Fukuda on Friday expressed concern about the monitoring, saying Japan hopes that it will not hinder free trade. The president of the Japan Iron and Steel Federation, Akio Mimura, who is also president of Nippon Steel, says his industry will be scrutinizing the import monitoring system as well. In addition to Japan and the European Union, South Korea and China also applauded the Bush administration's decision to end tariffs 15 months ahead of schedule. U.S. Trade Representative Robert Zoellick said Thursday that lifting the tariffs was not linked to the threatened foreign trade sanctions, but based on an evaluation that the U.S. steel industry was on the road to successful restructuring and profitability. But the president of the United Steelworkers Association, Leo Gerard, said foreign governments had engaged the Bush administration in a game of what he called "guts poker" and he said "instead of telling them to bring it on, the president blinked."
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OK, looks like we are ready (finally). My ISP reports that they hare having service interruptions due to weather. I'll launch this around GMT 1:00 AM. I will post the IP on post #1 when it's launched. both grilla57 and Indiansmoke are missing from the inital post though. Indiansmoke have also yet to chose a leader... Also for turn timer can we run something fast(12 hrs or 16 hrs?) since people aren't going to have much things to do every turn anyways. Also will we have a live session? just a heads up whiplash, on both the equal_inland_sea & equal_team_battleground is the best maps for your game... on a teamer OCC I'd reqcommend the team_battleground map. However you need to understand one thing about the "equal" maps. Yes, it does give lots of resources, but however it doesn't ALWAYS give all the resources. the equal part is that everyone will be missing the same resource if it doesnt appear. OK, Indiansmoke and Grilla are kinda like orphans. Do you two want to play as a team? Or is Grilla trying to line up somebody else? I'll hold the launch 'til tomorrow. He allready said duplicates would be ok. Oh and if indiansmoke finds a partner very very soon maybe he can join too? I don't have a partner, so you can start without me... Im more than ready, start the Mother..... OK, I'll launch it around 23:00 GMT today. It's launched, see post #1. OOPS, screwed up the start. Trying again. It's up now. I had to go to Huge Map with High Sea to fit 10 players in. Did you chose teams start together? cause we seem to be kinda far apart... EDIT: saw the huge ok. Fine then Why did you have to chose huge? Couldn't you just add more players? The map size was the reason for the restart. On a regular map it truncated the players to 7 upon launch. I tried large and it truncated the players to 9. I am not aware of any option to force team players to start near one another; although in my hotseat testing that seemed to always be the case. Why did you take it down now? going to restart it again? It crashed with the Network Socket Error. Restore file is loaded now. why is the civstats game named 2vs2vs2vs2 when it is 2vs2vs2vs2vs2 and wouldn't occ teamer be better?
https://forums.civfanatics.com/threads/2-player-team-occ-warlords.251021/page-6
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Be ready to fight the Dengue Virus once again. Dengue fever is a disease that is transferred through mosquito bites. Mosquitoes carry the Dengue virus. If such a mosquito bites someone they will be infected and develop dengue fever. This may cause the infected person in developing a high fever, headache, vomiting, muscle and joint pains, also a specific skin rash. In some cases dengue fever turns into the life threatening dengue hemorrhagic fever that causes bleeding, low level of blood platelets and blood plasma leakage or one can go into dengue shock syndrome. According to News Channel City42, we should all get ready to face dengue virus and all the illnesses that comes with it. As the days get hotter more and more mosquitoes will take life. With the increase in number of mosquitoes, which are the root of dengue diseases, the risk of getting bit and infected increases as well. Young children and/or students will be in danger of getting bit at all times. Cities like Rawalpindi and Karachi have also reported of people developing dengue fever in the recent month of February and current month of March. 1. Apply mosquito repellents, whichever suits you best. 2. Wear Long Sleeve shirts/uppers and long pants in order to cover your arms and legs. 3. You can use mosquito nets at night, so you can remain safe from mosquitoes while sleeping. 4. Try to fill or ask someone to fill any place where stagnant (standing) water is gathered. As dengue contaminated mosquitoes mostly bite in day time, we should follow these tips at all times in order to protect ourselves from dengue fever. Students and their parents should be on the lookout for mosquitoes, so the students can remain safe from getting infected by dengue fever. Students, if you observe that there is standing water gathered in a place then try to cover it up or ask someone else to cover it up with dirt. As standing water is where mosquitoes lay their eggs. Mosquitoes are the reason the dengue virus spreads. So we can all try our best to fight against them in these ways. In the coming days if you get the symptoms mentioned in the starting of this news article, you should go to a doctor right away. Don’t think that this is a passing fever and put your life at risk. Getting diagnosed at the right time for dengue fever is best for anyone who gets infected. Our team hopes for everyone to be safe and healthy!
https://www.beeducated.pk/news/be-ready-to-fight-dengue-virus-once-again-6275
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Hi. May I know if you come from Singapore and being treated acne by Dr Joyce? Im living in Singapore and suffering acne now. 8-month update: Sorry for the late update, was busy with bar exams, and just came back from a camping trip I have been going totally makeup free for the past 3 weeks, and it is totally awesome. Not a single drop of makeup. My skin feels and looks amazing. I've been using it coming to 8 months already and now I use it alternate nights. Next week onwards, I'll use it 3 times a week. I'm not completely clear yet. I'm afraid that completely stopping tretinoin will cause my skin to go back to square one. I'm going to use it 3 times a week for as long as I can. Hope that this will "maintain" my skin. Moisturiser With Retin-A? Confused! I cleanse, apply serum and moisturiser, then wait for 30-60 mins. Then I apply my tretinion cream. Then I apply clindagel as a spot treatment. That's how I do it, but other people may have different methods that work better for them. Do what feels right for your skin - all the best! Retin-A Micro Gel: The Burning/peeling! I agree. It is normal to peel and get slightly redder than normal when using retin-A, but not sunburny red... I think that the bp and retin-A combi is too harsh. Switch to a gentler cleanser because retin-A is a strong retinoid. About the foundation part, I totally understand what you mean about the peeling and flaking part which can be very embarrassing, especially when you're out with friends. After 27 Weeks..... Here's the picture update for Week 27! Comparing the pictures for Week 7 and Week 27 side by side. Week 7 during the initial breakout. Looking at the before and after pictures, I'm really amazed by the difference.
https://www.acne.org/profile/177980-roselilium/
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I very much appreciate your exhaustive answer, there is so much for me to go through, so much helpful information, I owe you one. As for what I'd like to do with it, well ideally I'd like to sculpt realistic figurines of authors I really like and some of the characters in their stories. A bust or two. I'd like to start real small by repairing an antique candlestick. I have a pair or wooden candlesticks from the early 1800's one of them had been burned and part of it will need to be sanded away and replaced with something I form to fit it , to be clear I'm not intending to make it look "never damaged" in fact I wouldn't mind making the repair contrast heavily, you know a little "wabi-sabi" effect. Here's the candlestick in question : http://i.imgur.com/c25bFb2.jpg http://i.imgur.com/sHCInu6.jpg http://i.imgur.com/whm84jD.jpg So "thank you" again and again for your answer.
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Episode 133: Live From Dragon Con 2016 We're back for our 7th year at Dragon Con in Atlanta, Georgia! This time, we're joined by Scott Sigler and Turquoise Jeep to get drunk and play Don't Get Brody'd, PowerPoint Roulette, and DragonCon Cosplay Thunderdome! Show Notes Show notes by Leon - Latest version on the DCTVpedia Guests on Guests on Guests We got Scott Sigler! We got Flynt Flossy! We got Whatchyamacallit! And we got Turquoise Jeep's latest signee, Pierre Cashmere (I think that's what it is, I can't find him on the internet). Rogue's Brew Brian and company over at Scam Stuff are selling a homebrew beer kit, allowing everyone to brew their own beer. The recipe was put together buy TallBeerDude (he was on an episode or two of NSFW.) Anyway, Waffleophagus (how the fuck do you spell his name? Is that right?) brewed some and brought it for the panel to drink. It's a little heavy on the alcohol. All Setups Magician Remember last week during the aftershow when Brian and Justin talked about doing an All Setup Magician show where they set up a bunch of tricks but none of them pay off? Well they actually did it! You can check out the Periscope from JuryFacts here. Don't Get Brody'd - Greg - He worked at the Disneyland monorail and a dude was super sick. He pulled over a trash can for him to let him puke. The dude ends up pulling down his pants and shits in the trash. (1:15) - His buddy with huge gauges in his ears passed out and someone put a padlock in his ear. They called a locksmith, but they refused to help him. I guess they found the culprit and the guy started beating the shit out of him and yells "JACKSON CITY BITCHES". They ended up on reddit (1:50) - Colin - His buddy had a pipe burst in his house. Brody'd - Stacy - This is mundane, I'm probably gonna get brody'd. Brody'd - Krunchy - Her and her friends go to the bar and she's yacking in the bushes at 2am. Now she's in no condition to drive… Brody'd - Marcus - There's a really friendly janitor at his school and they're talking about mario for a bit. After a while the janitor tells him to get out of here. Whatevs. A couple days later, he's watching the news and he sees a sketch of the janitor who got arrested for molestation. Brody'd - Thomas - His roommate and he dropped acid and took a road trip. They stop in Quincy, Florida. There's a ton of racist white dudes, and two of his friends are asian. Brody'd - CJ - He was making a music video for a school project. The director of the video took the name of the song "She's So High" a little too literally. Brody'd Winner: JACKSON CITY BITCHES! PowerPoint Roulette This is the game where the panelists give a presentation on a subject suggested by the audience with a PowerPoint slideshow full of random pictures. The slides were put together by long-time Chatrealmer Patrick Delahanty. Subjects - Justin - Loch Ness Monster - Scott Sigler - Cleopatra - Whatchyamacallit - Sexually suggestive children's cartoons - Brian - TSA DragonCon Cosplay Thunderdome This is the quintessential Diamond Club at Dragon Con game. The panelists each pick a cosplayer from the audience who will face off against one another in violent, metaphorical combat. Contestants - Brian - Louise Belcher from Bob's Burgers - Justin - Captain Morgan - Scott Sigler - Afro Deadpool - Turquoise Jeep - Punished "Venom" Snake, woman from the Terran Empire in the mirror universe of Star Trek and "The lady that was next to Afro Deadpool" Round 1 - Snake, girl and "lady" vs. Captain Morgan - Winner - Captain Morgan - Louise Belcher vs. Afro Deadpool - Winner - Louise Belcher Round 2 - Captain Morgan vs. Louise Belcher - Winner - Captain Morgan Flynt Flossy Teaches Scott Sigler to Dance Flynt Flossy is featured in the official Twitter app when you want to send a gif of someone dancing. This gif. He walked Scott through the steps during the show. Diamond Time It's a live show, no Diamond Time this week. Belt Winner - Nobody? Great Quotes - "I love dragons" - Captain Morgan Fun Facts - Brian gave his credit card info to Chatrealmer, Waffleophagus, to book his hotel room Characters - Captain Morgan No preshow doc this week
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Designer Silvia Venturini Fendi took inspiration from the 1920s dandy at her fashion house’s show on Saturday, punctuating refinement with touches of eccentricity. Blazers were transformed into capes, knitwear featured sizeable chest cutouts and the accessories veered towards the flashy. The collection also aimed for a more fluid interpretation of typically gendered clothes, with wide-leg pants ballooning into half-skirts. “We women wear men’s jackets, I do not see why they could not take inspiration from our wardrobe,” said the designer, the granddaughter of the Italian fashion house’s founders. At Sicilian duo Dolce & Gabbana’s show, casual and sartorial styles mixed in a celebration of returning to the great outdoors. Tailored to appeal to a younger generation, the show featured rap and punk music orchestrated by Machine Gun Kelly. Models wore loose-fitting coats with leopard or zebra prints, white suits embroidered with pearls or tight-fitting pants and tuxedos with wide shoulders and a cinched waist. Others were wrapped up in thick, oversized down jackets in bold colours or eco-friendly furs, ready to face the winter cold during post-Covid excursions. And like at Fendi, the skirt featured as part of the male wardrobe, with the designer duo citing young people’s ability to choose their clothes freely, without worrying about gender. Both shows carried on despite the disruption sown across Europe by the surging Omicron variant, which has curtailed the fashion week calendar. After Giorgio Armani announced its withdrawal, the number of physical shows was reduced from 23 to 16. Eighteen brands opted for a purely virtual presence, while others presented their collections by appointment. Still, those that went ahead, like Dsquared2 on Friday, embraced the return to the catwalk. In their first live show in two years – attended by football star Zlatan Ibrahimovic – the Canadian twins behind the label displayed a festival of bright yellows, pinks, reds and blues alongside floral patterns, sequins and crystal embroidery. With a glimmer of hope and much enthusiasm, Dsquared2’s globe-trotting styles were a nod to getting out of the cocoon and going on a long-awaited trip.
https://www.thesouthafrican.com/lifestyle/fashion-and-beauty/milan-mens-fashion-week-post-covid-excursions/
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What’s good, mates. You've decided that big boy Vasiliev Podkolzolofin is our second best prospect, but it was close. I gave you the extra day because of the slim 15 vote gap, but it never came close to closing. Now, we have some tougher choices to make. Do we go with Thatcher, who could be our goalie of the future? Do we go with Juolevi, who got 13 points in 18 games and looks to be the number 1 guy in Utica right now? What about a dark horse guy, like 5’9 Hogs, or Tyler Madden? Someone else? You know the drill by now, make a choice and debate it down below. Let’s hope to see some more discussion, as that’s why I’m doing this! If they’re eligible for a Calder then they're included. Went with OJ partially because i want to throw him some shade after many belly aching posts I’ve made about him, and the rest because he’s harder to replace. Demko is deserving too given he’s in the show now, but I believe when OJs 24 he could have a bigger impact. Don’t think Podz has done enough to prove he’s with these guys yet but get the selection too. Could be some recency bias too, or “Olli sucks.” I wouldn’t be surprised if some people are anti-DiPietro because of the San Jose game too. Demko was Utica's life force in the time he was there. OJ was my selection behind Hughes and Podkolzin ( I have ruled Demko out - he's already in ), OJ's development goes full on this coming season. I trust Benning's selection, OJ at some point this season is in a regular rotation. Jett Woo is missing from the list. I am pretty sure that was an unintentional slip as it would not surprise me to see Woo get a few votes at this stage, although I personally think that Demko deserves to get the #3 spot easily. My main reason for thinking that Demko deserves to win at this stage is that he has already shown he can play effectively at the NHL level. His save percentage last year in the NHL was actually slightly above Marky's and better than the NHL average, although that was in a small sample size. Anyway, back to Woo. It seems to a near-consensus view that OJ is next best D-prospect after Hughes. I would like to put in an argument for Woo. In his draft +1 year, Woo had 12 goals and 54 assits for 66 pts in 62 games in the WHL, for 1.06 points per game (PPG). In his draft +1 year, Juolevi had 10 goals and 32 assists for 42 pts in 58 games for 0.72 PPG, significantly behind Woo. Woo played on a pretty good team but Juolevi played on a better team, so quality of teammates probably helped Juolevi more than Woo. (London had 99 pts in 68 games and Moose Jaw had 88 pts in 68 games.) And the OHL and WHL are very similar in quality. Also, Woo is regarded as very strong defensively, although OJ also played key defensive minutes in his draft+1 year. There is probably no clear basis for saying one guy was better than the other defensively. Both guys have had worrying injury problems, so there is probably no real difference on that score. Woo brings the additional advantage of contributing much more to the physical game. Juolevi was a high draft pick and is generally regarded as having high level (but not elite level) skills and a high hockey IQ, but I think Woo is actually progressing faster than Juolevi did at a comparable stage (i.e. in his draft +1 year) and also has good skills and a high hockey IQ. Juolevi is closer to being NHL ready, but he was drafted two years before Woo, so he should be a lot closer. In terms of what we can expect of each guy as he approaches his mature or peak performance level, it don't think it obvious that Juolevi will be better than Woo. If someone did not know about the relative draft position or about the extensive debate over the Juolevi pick but just looked at on-ice performance (adjusted for age), I think Woo has a strong case. is demko in or out ? im so confused lol one says in one says out demko is technically eligible for the calder ? right? People keep adding their own rules to my list... that’s fine with me, although a little annoying, but I’m basing it off of Calder eligibility. Analysts are as well, and they’ve done this sort of thing for a while. Demko for me. Demko. Elite starter potential. Guess no more. Camp and pre-season will be fun this year. Will be interesting to see how some of our prospects do during that period, who gets cut, who stays etc. As promised, went with Demko. I think Podkolzin and Demko were neck and neck for second/third with everyone else a big step back. Juolevi, Woo, Hoglander and others show a lot of promise and hopefully become NHL players. At this time they appear to be bottom 4/bottom 6 players. We need these types of players and if they can exceed this we are really in for an exciting few years. Back on topic I think Demko has proven he can play at the NHL level and is no where near his ceiling yet ... having a solid goalie as your #3 prospect while EP is still on an ELC is a nice spot to be in. I went with Demko but I could easily have voted for Juolevi. 1 was obvious, tier two is playing out exactly as the pyramid is with the guys getting votes. Wow what a prospect group we have... I'm so grateful to be a Canucks fan. #3 is a tough one to vote on... Lots of candidates. I'll give my vote to Olli though. I believe he'll soon bust out. Also Carson Focht lol... I hope this kid makes the main squad one day. Focht is #20 playing for team Canada vs Sweden on TSN right now in the summer showcase. Kid looks good.
https://forum.canucks.com/topic/391063-poll-cdc%E2%80%99s-top-ten-canucks-prospects-day-3/
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Another reason to never live in California. I'm a landscaper with my buddy in the spring and summer mostly. Neither of us could even imagine how we'd get by using electric mowers, especially the big riding mowers. Also, I highly, highly doubt there's weed whackers and leaf blowers that are anywhere NEAR as good as the ones we have are. Seems like it wouldn't really make much of a difference with CO2 output unless you have clean energy, such as solar, at your house. I just told this to my buddy and he says "that sounds like a nightmare." Millions of cars and billionaire corporations spewing the majority of the CO2 into the air, but yeah... Landscapers are the problem.
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When V2O Foods Fresh Krill frozen fish food says fresh, they mean it. The frozen food is never cooked and is flash frozen and gutloaded krill to give your carnivorous fish maximum flavor and nutrition. Krill is naturally loaded with antioxidants and carotenoid pigments to support overall health and vibrant coloration. This recipe features Antarctic Krill Superba that is also gut-loaded with marine phytoplankton for added nutritional value. And since the Krill Frozen Fish Food is individually quick frozen, you can easily feed one krill at a time for maximum feeding convenience. A 4 oz. package retails for around $6 USD.
2992e7ad86368b65672483cc5dfa1935
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He has moved clubs several times since playing at Ajax, such as Barcelona, Inter Milan, AC Milan, and now PSG. He's very talented and can single-handedly change the game for a team. I saw him play for Inter against Atalanta in Milan back in the summer of '09 and he was incredible. When he's on form, definitely one of the best strikers in the world. He's got a bit of an ego though and is known to cause dressing room drama. Edit: [One of his goals for Milan.] (http://youtu.be/cR46fsPIoI4) [One for Sweden against France at the Euros this year.] (http://youtu.be/G5sGuG5sBDg)
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The Line-R automatically corrects brownouts (by boosting low voltage) and overvoltages (by stepping down high voltage) from the power utility service to levels that are safe for computers, as well as other sensitive equipment. APC's Line-R provides the highest degree of protection from line voltage sags and swells, and has been designed for many years of reliable, maintenance-free service.
https://www.ebuyer.com/53034-apc-line-r-600va-automatic-voltage-regulator-le600i
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Hello, I have difficulties in establishing a connection to the Internet after I had startet the VPN Client. The behavior is like the following: - I start the VPN Client and enter my credentials - It seems that the VPN Client establishes the connection to my school's network properly - After a few second I can see the Icon "No internet access" in the status bar from windows (right lower corner) Does anybody have an idea what I can do to establish the connection properly? Many thanks! Mike This is caused by the VPN policy of your school. You should contact the VPN server administrator for more information. Meantime you can do some changes on your computer. Please refer: You Cannot Connect to the Internet After You Connect to a VPN Server
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Are you, like me, driven to explore the unknown? At the Jet Propulsion Laboratory, I serve as a rover Tactical Activity Planner, and I develop software to make rovers and orbiters more autonomous. Smart robots can help us learn from afar, and one day they can help us in person. I’m eternally curious, dedicated, tenacious, adaptable, and extremely reliable. I can’t wait to put my science, engineering, and athletic skills to use in exploring Mars. My favorite activities involve learning something new. Last year featured my first triathlon, hang-gliding, and starting a new degree program. I also love knitting, blues dancing, and trips to foreign lands. I enjoy sharing what I’ve learned, at http://www.wkiri.com/today/. Feel free to comment!
https://community.mars-one.com/profile/3e9d7374-d74d-41b3-b568-fb30053f216b
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From zombie comedies to movie serials, this week’s new Blu-ray and DVD offerings have something for everyone! Check out the latest batch of titles that are now available! It’s a decade into the zombie apocalypse, and Tallahassee (Woody Harrelson), Columbus (Jesse Eisenberg), Wichita (Emma Stone), and Little Rock (Abigail Breslin) are as dysfunctional as ever. Joined by fellow survivors Nevada (Rosario Dawson) and Madison (Zoey Deutch), can the group defeat a batch of the undead monsters that have evolved into even deadlier creatures? Avan Jogia and Luke Wilson also star in this action-packed sequel to the 2009 horror/comedy hit. With his body giving out from the excesses of his adult life, veteran filmmaker Salvador Mallo (Antonio Banderas) finds himself invited to a revival screening of the project that made his name over 30 years ago. As he self-medicates with heroin provided by his long-estranged leading man (Asier Etxeandia), he revisits episodes from his past in hopes of finding a way forward. Personal narrative from Pedro Almodovar co-stars Penélope Cruz, Julieta Serrano, Nora Navas. Taut and timely crime thriller focuses on Alicia West (Naomie Harris), a rookie New Orleans police officer whose body cam records the killing of a drug dealer by some of her fellow cops. Framed for the murder, Alicia must turn to a childhood friend (Tyrese Gibson) for help as she attempts to safeguard the footage while dodging the corrupt officers and ruthless crooks who are all trying to kill her. With Mike Colter, Frank Grillo, Reid Scott. Sprung from a Vichy POW camp in Algiers, a British officer (Rock Hudson) learns that he’s been tasked to lead a cadre of English and German-Jewish commandos across the Sahara. Their endgame: a certain suicide bid to knock out Rommel’s crucial fuel depot in Tobruk, Libya. Thrilling, fact-based tale of action and intrigue co-stars George Peppard, Nigel Green, Guy Stockwell, and Leo Gordon (who scripted). Goofy gridiron comedy, based on Dan Jenkins’ novel, follows pro football teammates and pals Billy Clyde Puckett (Burt Reynolds) and Marvin “Shake” Tiller (Kris Kristofferson). After completing a self-help program, Shake starts romancing team owner’s daughter Barbara Jane (Jill Clayburgh)…whom Billy Clyde also has his sights set on. With Robert Preston, Roger E. Mosley, Brian Dennehy, and Burt Convy. The always-sinister Bela Lugosi stars as evil Dr. Zorka, whose weapons in his scare-a-minute battle for world domination include an invisibility belt, mechanical spider bombs, a giant robot, and a substance that causes suspended animation. Exciting 12-chapter serial also stars Robert Kent, Dorothy Arnold. Hired by desperate ranchers to rout the gang of rustlers bleeding them dry, sharp-shooting cowboy Buck Gordon (Buck Jones) tracks the desperadoes to the ghost town where they’re holed up. Can he also help an old prospector (Tom Ricketts) and his beautiful daughter (Madge Bellamy) when the same owlhoots try to jump their gold claim? Universal sagebrush chapterplay also stars Francis Ford, Walter Miller, William Desmond, Ethan Laidlaw. 12 chapters. An app that can tell you precisely when you’re going to die reveals that nurse Quinn Harris (Elizabeth Lail) has but a few days before she bites the dust. Matt Monroe (Jordan Calloway) has received a similarly imminent prediction. Joined by Quinn’s younger sister Jordan (Talitha Eliana Bateman), can they beat death and alter their destiny…while there’s still time? Fast-paced horror tale also stars Peter Facinelli, Tichina Arnold, Dillon Lane. This second epic screen take on Edna Ferber’s best-selling American West saga stars Glenn Ford as late 19th century adventurer Yancy Cravat, whose bid to claim a stake of territory and a different chapter in his life during the Oklahoma Land Rush may ultimately cost him a happy existence with new wife Sabra (Maria Schell). Arthur O’Connell, Anne Baxter, Russ Tamblyn, Mercedes McCambridge, Vic Morrow, Harry Morgan also star; Anthony Mann directs. It seems like Hollywood suits never get it–not in greenlighting a remake of “Bluntman and Chronic” with Kevin Smith (Kevin Smith) in the director’s chair, and certainly not in cutting creators Jay (Jason Mewes) and Silent Bob (Smith) out of their percentage again! Our aging stoner heroes road trip west on another mission of sabotage, as writer/director Smith knowingly tweaks franchise filmmaking and woke casting; with Shannon Elizabeth, Harley Quinn Smith, Justin Long, and tons of cameos. How much difference can a single decision and a few minutes make in a person’s life? That question is the basis for this romantic tale featuring Gwyneth Paltrow as Helen Quilley, a Londoner taking the subway home after being fired from her PR job. As the film’s parallel scenarios show, whether Helen catches or misses a train determines her relationship with a two-timing boyfriend (John Lynch)…and a possible new romance. John Hannah, Jeanne Tripplehorn also star. In 1880s Arizona, with settlers being terrorized by the renegade Apache Ulzana (Joaquin Martinez) and his followers, the Army dispatches a cavalry troop spearheaded by a self-righteous young officer (Bruce Davison) and a cynical veteran scout (Burt Lancaster). Their grueling hunt for the war party, though, may leave all irrevocably changed, in Robert Aldrich’s sobering Vietnam allegory; Richard Jaeckel, Jorge Luke also star. Western action is mixed with an allegorical look at ’50s McCarthyism in this tale starring John Payne as Dan Ballard, a frontier sheriff who must fight to prove his innocence when a U.S. marshal (Dan Duryea) comes to town with a warrant for his arrest on theft and murder charges. Lizabeth Scott, Dolores Moran, Emile Meyer, Alan Hale Jr. co-star; directed by Allan Dwan and written by blacklisted writer Karen DeWolf. Born and bred in Georgia, possessing a country-boy exterior, and spouting folksy nuggets of wisdom, attorney Ben Matlock (Andy Griffith) was actually a razor-sharp defense lawyer who would not only prove his clients innocent of murder but would often find the real killer. The 1986-95 CBS series’s changing cast included Kene Holliday, Linda Purl, Nancy Stafford, Julie Sommars. 178 episodes on 52 discs. Click here for a rundown of all of this week’s new releases!
http://www.moviefanfare.com/?p=54587
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2. Project must include a die-cut** and follow the theme of the challenge. 7. Please remember when linking up your project to link up to your post and not just your blog. **For these challenges, a die-cut is anything made with a manual or an electronic die-cutting machine. (Spellbinders,Cricut, MFT dies, Shilouette, etc.). Store bought die-cuts are also acceptable.
https://cutitupchallenges.blogspot.com/p/challenge-rules.html
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Of all the bad actors who attached themselves to Donald Trump in the course of the Russia scandal, former campaign manager Paul Manafort may be the baddest, and so it would be fitting -- and overdue, as well -- if he ends up trading one of his Italian designer business suits for an orange prison jumpsuit after his bail hearing on Friday. Besides which, those two home confinement monitoring ankle bracelets he has been wearing kind of ruin his man of the world look. In addition to Manafort's all-around badness, which includes a long career making and squandering several fortunes while lobbying on behalf of a rogue's gallery of corrupt foreign leaders, including Ferdinand Marcos in the Philippines, Mobutu Sese Seiko in the Democratic Republic of Congo, Angolan guerrilla heavyweight Jonas Savimbi and more recently pro-Kremlin autocrats, he has believed himself to be above the law. It was not particularly surprising that Manafort's lawyers mounted a series of largely frivolous challenges to Robert Mueller's authority after the special counsel charged he and longtime assistant Rick Gates with a slew of money laundering and tax and foreign lobbying violations last October 30 and expanded on those charges on February 22 based on evidence that not only contradicted White House statements that Manafort was an inconsequential player who did all that bad stuff prior to joining the campaign in early 2016, but was continuing doing bad stuff right up to and long past his indictment. It also was not particularly surprising that Manafort would refuse to plead guilty and agree to cooperate with Mueller as did Gates and three other non-Russian Mueller perps -- Michael Flynn, George Papadopoulos and Alex van der Zwaan -- despite the probability he will spend the rest of his life in prison because of the multitude and seriousness of the charges. But it was jaw dropping even by Trumpian standards when Manafort violated not once but twice the generous home release conditions approved by federal Judge Amy Berman Jackson and secured by Manafort putting up a $10 million bond based on his properties in New York, Virginia and Florida. Last December 4, Manafort was back in Judge Jackson's courtroom where he was scolded for ghost-writing an English-language op-ed piece about his work for deposed Ukrainian president and Vladimir Putin puppet Viktor Yanukovych with his Kiev office manager Konstantin Kilimnik, who has problematic ties with Russian intelligence and was a likely conduit between the Trump campaign and Russians who were merrily undermining American democracy by interfering in the 2016 election. This was a violation of a court order banning Manafort from making statements to the press, prompting Jackson to note that "This is a criminal trial, not a public relations campaign." Then last Monday Mueller notified the court he had evidence that Manafort and Kilimnik had been tampering with witnesses after journalists Alan Friedman and Eckart Sager revealed that in late February they had been contacted by their one-time pals Manafort and Kilimnik as part of a scheme to try to shape and coordinate the accounts of former business partners given to prosecutors that were, in part, the basis for the indictments. In other words, to lie. These orchestrated lies were related to the work of former Manafort-Kilimnik partners to tamp down international criticism of Yanukovych for corruption, persecuting rivals and pivoting toward Russia and Putin. Last Friday, Manafort was slapped with two additional charges -- obstructing justice and attempting to obstruct justice -- and Kilimnik became the 20th notch in the special prosecutor's belt when he was indicted on similar charges. Kilimnik, as a Russian national, is beyond Mueller's reach as are the 13 Russians and three Russian firms previously indicted for illegally using social media to sow political discord in the election through devastatingly effective actions that supported Trump's candidacy and disparaged Hillary Clinton. But it is pretty much the consensus view of former white-collar criminal prosecutors that Manafort has done his dash and his days wearing two home confinement monitoring ankle bracelets (one for indictments returned by a Virginia grand jury and another for those returned by a Washington grand jury because he has refused to allow the cases to be consolidated) may end on Friday when Judge Berman rules at a bail hearing as to whether Manafort should be incarcerated for his serial indolence. That incarceration presumably would continue through the first of Manafort's two scheduled trials, which begins on July 10 and should be an appropriate backdrop to the final weeks of the midterm elections lest anyone need reminding what Trump has wrought on the republic with the help of thugs like Manafort and the practiced silence of Vichy Republicans. Manafort's penultimate act prior to joining the Trump campaign was to engineer a social media-based disinformation campaign for Yanukovych that anticipated what Russia and its army of trolls did in the 2016 U.S. election. It was Manafort who lobbied Trump to join his campaign and work for free despite being deeply in debt. There was a spike in campaign contacts with Moscow almost immediately after he joined the campaign and a further uptick when he was named campaign manager. That is a pretty strong circumstantial case for collusion, but the distance between circumstantial and provable can be substantial even if seeming coincidences in the Russia scandal are anything but. Court filings by Mueller indicate that he has tacked away from investigating Manafort's financial crimes to his campaign activities. These filings hint at Manafort and Gates being cutouts to convey information between the campaign and Putin's cyberwarriors, with Kilimnik being the conduit. Mueller also obtained a new search warrant for phone records and bank account information pertaining to Manafort after Gates agreed to cooperate. The phone records may be what are called "historical cell site information" in investigative parlance, meaning that Mueller is tracking the timing of Manafort's previous movements. It has been fascinating -- in the grotesque sort of way that a slow-motion train wreck is fascinating -- to watch the Russia scandal unfold. From the first intimations in late 2016 that the dark hand of Putin was at work to elect Trump to our dawning realization that the Trump campaign colluded in that effort to our astonishment at how enormous their involvement was, there has been one jaw-dropping revelation after another. And so the notion that the Kremlin may have sent Manafort into a campaign he was soon to manage to make sure that it helped Putin play his evil game would at one time have seemed preposterous, but now is increasingly possible. Does that explain Manafort's refusal to cooperate? We may know more on Friday, as well as whether trading charcoal grays for orange will have a clarifying effect on the baddest of the bad. Glad someone has the stomach to follow this story through all the muck Shaun, and report it to us without all the tedious and exhausting drama of cable news. Thank you for what you do. Bob Cesca calls it "stupid Watergate." The thing that maybe stopping Manafort from flipping is the fear that Novachok will be smeared on his cell door as he's waiting for his presidential pardon.
https://kikoshouse.blogspot.com/2018/06/time-for-paul-manafort-to-trade-in-his.html
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- Research article - Open Access - Published: Water extract of the fruits of Alpinia oxyphylla inhibits osteoclast differentiation and bone loss BMC Complementary and Alternative Medicine volume 14, Article number: 352 (2014) 1802 Accesses 10 Citations 1 Altmetric - Abstract Background Excessive bone resorption by osteoclasts causes pathological bone destruction, seen in various bone diseases. There is accumulating evidence that certain herbal extracts have beneficial effects on bone metabolism. The fruits of Alpinia oxyphylla has been traditionally used for the treatment of diarrhea and enuresis. In this study, we investigated the effects of water extract of the fruits of Alpinia oxyphylla (WEAO) on osteoclast differentiation and osteoclast-mediated bone destruction. Methods For osteoclast differentiation assay, mouse bone marrow-derived macrophages (BMMs) were cultured in the presence of RANKL and M-CSF. RANKL signaling pathways and gene expression of transcription factors regulating osteoclast differentiation were investigated by real-time PCR and Western blotting. A constitutively active form of NFATc1 was retrovirally transduced into BMMs. Bone resorbing activity of mature osteoclast was examined on a plate coated with an inorganic crystalline calcium phosphate. The in vivo effect against bone destruction was assessed in a murine model of RANKL-induced osteoporosis by micro-computed tomography and bone metabolism marker analyses. Results WEAO dose-dependently inhibited RANKL-induced osteoclast differentiation from BMMs by targeting the early stages of osteoclast differentiation. WEAO inhibited RANKL-induced expression of NFATc1, the master regulator of osteoclast differentiation. Overexpression of a constitutively active form of NFATc1 blunted the inhibitory effect of WEAO on osteoclast differentiation, suggesting that NFATc1 is a critical target of the inhibitory action of WEAO. WEAO inhibited RANKL-induced expression of c-Fos, an upstream activator of NFATc1, by suppressing the classical NF-κB signaling pathway. WEAO also inhibited RANKL-induced down-regulation of Id2 and MafB, negative regulators of NFATc1. WEAO does not directly affect bone resorbing activity of mature osteoclasts. In accordance with the in vitro results, WEAO attenuated RANKL-induced bone destruction in mice by inhibiting osteoclast differentiation. Conclusions This study demonstrates that WEAO exhibits a protective effect against bone loss by inhibiting RANKL-induced osteoclast differentiation. These findings suggest that WEAO might be useful for the prevention and treatment of bone diseases associated with excessive bone resorption. Background Bone is a dynamic organ that undergoes continuous remodeling through osteoclast-mediated bone resorption and osteoblast-mediated bone formation. The bone remodeling process is highly controlled by various factors and is necessary to repair damaged bone and to maintain mineral homeostasis [1, 2]. Osteoclasts are unique, multinucleated giant cells that form through fusion of monocyte/macrophage lineage precursor cells. Macrophage colony-stimulating factor (M-CSF) and receptor activator of NF-κB ligand (RANKL) are critical cytokines required for osteoclast differentiation [3–5]. M-CSF supports the survival and proliferation of osteoclast precursors [6]. In addition, M-CSF stimulates the expression of RANK, the receptor for RANKL, in osteoclast precursors [5]. The binding of RANKL to RANK receptor on osteoclast precursors activate down downstream signaling pathways including mitogen-activated protein kinases (MAPKs) and NF-κB by recruiting adaptor molecules such as tumor necrosis factor receptor-associated factor 6, which regulate transcription factors involved in osteoclast differentiation [7–10]. Accumulating evidence suggests that nuclear factor of activated T cells cytoplasmic 1 (NFATc1) integrates RANKL signaling for terminal differentiation of osteoclasts [1]. Conditional deletion of NFATc1 in the myeloid cell lineage results in osteoclast-poor osteopetrosis, and NFATc1-deficient osteoclast precursors fails to differentiate into osteoclasts in vitro[11]. In addition, overexpression of NFATc1 can induce the differentiation of osteoclast precursors into mature osteoclasts even in the absence of RANKL [12]. Thus, NFATc1 is considered the master regulator of osteoclast differentiation. RANKL stimulates the expression and activation of NFATc1 in osteoclast precursors by regulating other transcription factors. It has been shown that RANKL-induced NFATc1 expression depends on NF-κB and c-Fos, which are activated by RANKL [9, 12]. It was also reported that RANKL suppresses the expression of transcriptional repressors such as inhibitors of differentiation/DNA binding (Ids), v-maf musculoaponeurotic fibrosarcoma oncogene family protein B (MafB), and interferon regulatory factor 8 that inhibit NFATc1 expression and osteoclast differentiation [13]. The RANKL/RANK pathway is not only crucial for normal bone remodeling but also primarily responsible for pathological bone destruction in various bone diseases such as postmenopausal osteoporosis, Paget’s disease, rheumatoid arthritis, and lytic bone metastasis. Thus, the RANKL/RANK pathway is considered to be an attractive therapeutic target for bone destructive diseases [2]. There is a growing interest in herbal resources including common vegetables and fruits as a promising approach for the prevention and treatment of bone-related disorders such as osteoporosis [14, 15]. We evaluated the inhibitory effects of various herbal extracts on RANKL-induced osteoclast differentiation from its precursor cells as a screen for potential herbal candidates with bone protective properties. Water extract of the fruits of Alpinia oxyphylla (WEAO) was found to have a relatively strong inhibitory activity against osteoclast differentiation. The fruits of A. oxyphylla, called Yizhi, Yakuchi, and Ikji in Chinese, Japanese, and Korean, respectively, has been traditionally used for the treatment of diarrhea and enuresis [16]. Pharmacological studies have shown that the fruits of A. oxyphylla possess a wide range of biological activities, including anti-diarrheal [17], anti-tumor [18], anti-anaphylactic [19], anti-ulcer [20], and neuroprotective [21, 22] activities. However, the effect of the fruits of A. oxyphylla on bone metabolism has not been studied. Here, we have investigated the anti-osteoclastogenic effect and action mechanism of WEAO. Methods Reagents and antibodies Fetal bovine serum (FBS), α-modified minimal essential medium (α-MEM), and penicillin/streptomycin were purchased from Gibco BRL Life Technologies (Grand Island, NY, USA). Recombinant M-CSF and RANKL were obtained as described previously [23]. 1α,25-dihydroxyvitamin D3, prostaglandin E2, and chrysin were obtained from Sigma-Aldrich (St. Louis, MO, USA). Tectochrysin and nootkatone were obtained from ChemFaces (Wuhan, China). Antibodies against phospho-JNK1/2 (Thr183/Tyr185), JNK, phospho-p38 (Thr180/Tyr182), p38, phospho-IκBα (Ser32), and IκBα were obtained from Cell singling Technology (Danvers, MA, USA). Antibodies against NFATc1 and c-Fos were purchased from Santa Cruz biotechnology (Santa Cruz, CA, USA). Preparation of WEAO Air-dried fruits of A. oxyphylla were obtained from Yeongcheon Oriental Herbal Market (Yeongcheon, Korea) and authenticated by an expert botanist, emeritus Prof. Ki-Hwan Bae (Collage of Pharmacy, Chungnam National University). A voucher specimen was deposited at the herbarium of the KM-Based Herbal Drug Development Group, Korea Institute of Oriental Medicine. The materials were extracted by boiling in distilled water (1:10, w/v) for 3 h. The water extract was filtered with standard sieves (106 μm; Restsch, Haan, Germany) and then lyophilized. The lyophilized powder (yield: 5.52% of dried fruits) was re-suspended in distilled water and centrifuged at 10,000 g for 5 min to prepare WEAO. For in vitro experiments, WEAO was filtered through a 0.2 μm filter. High performance liquid chromatography (HPLC) analysis HPLC analysis of WEAO was conducted using a Hitachi LaChrom Elite HPLC system (Hitachi High Technologies Corp., Tokyo, Japan). The chromatographic separation was carried out using a Kinetex C8 column (4.6 mm × 100 mm, 2.6 μm, 40 °C). The mobile phase was 0.1% trifluoroacetic acid in deionized water (A) and acetonitrile (B) with a step gradient elution (0–3 min, 5%–5% B; 3–63 min, 5%–70% B; 63–73 min, 70%–70% B). A mixture of standard compounds (Chrysin, Tectochrysin, Nootkatone; each 200 μg/mL) and WEAO (100 mg/mL) were dissolved in methanol and filtered through a 0.2 μm syringe filter prior to injection for HPLC analysis. Osteoclast differentiation assay Bone marrow cells were collected by flushing the femurs and tibias from 6- to 7-week-old male ICR mice with α-MEM. After removing red blood cells, BMMs were prepared from bone marrow cells with M-CSF (60 ng/mL) in α-MEM complete medium containing 10% FBS and 1% penicillin/streptomycin as described previously [24]. For osteoclast differentiation, BMMs (1 × 104 cells/well in a 96-well plate) were cultured in α-MEM complete medium supplemented with M-CSF (60 ng/mL) and RANKL (100 ng/mL) for 4 days. To investigate the effect of WEAO on osteoclast differentiation, WEAO was added to the cultures simultaneously with RANKL at day 0 or after 1, 2, or 3 days. Cells were replenished with fresh medium and treatments on the third day of culture. To assess osteoclast differentiation, cells were stained for tartrate-resistant acid phosphatase (TRAP) activity as described below. TRAP-positive multinucleated cells containing more than three nuclei and larger than 100 μm in diameter were counted as osteoclasts. TRAP assay TRAP staining was performed using TRAP buffer (50 mM sodium tartrate and 0.12 M sodium acetate, pH 5.2) with naphthol AS-MX phosphate and fast red violet LB salt (Sigma-Aldrich) as described previously [23]. Serum TRAP isoenzyme 5b (TRAP 5b) activity was determined using the fluorogenic substrate, naphthol AS-BI phosphate (Sigma-Aldrich). In brief, 20 μL of serum was incubated with 100 μL of TRAP 5b reaction buffer (2.5 mM naphthol AS-BI phosphate, 50 mM sodium tartrate and 0.12 M sodium acetate, 2% NP-40, and 1% ethylene glycol monomethyl ether, pH 6.1) for 30 min at 37°C, and the reaction was stopped by adding 120 μL of 0.1 M NaOH. Fluorescence was measured at an excitation wavelength of 405 nm and an emission wavelength of 520 nm. Cell viability assay BMMs (1 × 104 cells/well in a 96-well plate) were cultured with or without WEAO (10–160 μg/mL) in the presence of M-CSF (60 ng/mL) for 2 days, and the viability of BMMs was evaluated with Cell Counting Kit-8 assay (Dojindo Molecular Technologies Inc., Rockville, MD, USA) according to the manufacturer’s protocol. Animals and RANKL-induced osteoporosis model All animal experiments were carried out according to the protocols (permission number: 12–090) approved by the Institutional Animal Care and Use Committee Guidelines of Korea Institute of Oriental Medicine. 5-week-old male ICR mice were purchased from Orient Bio Inc. (Seoul, Korea) and housed under constant environmental conditions (22 ± 1°C, 55 ± 10% humidity, and 12 h light/dark cycle) with free access to a standard animal diet and water. 7-week-old mice were orally administered with vehicle (distilled water) or WEAO (0.25 g/kg of body weight) twice daily for consecutive 5 days, and RANKL (1 mg/kg of body weight) or PBS was intraperitoneally injected on days 3 and 4. On day 6, fasting blood samples and the right femurs were collected. Measurement of serum markers of bone resorption and bone formation Serum levels of C-terminal cross-linked telopeptide of type I collagen (CTX) and osteocalcin were measured using a RatLaps EIA kit (Immunodiagnostic Systems Inc., Fountain Hills, AZ, USA) and a mouse osteocalcin EIA kit (Biomedical Technologies Inc., Stoughton, MA, USA), respectively. Micro-computed tomography (micro-CT) analysis Micro-CT scanning of the distal femur was carryout out on SkyScan 1076 CT scanner system (SkyScan N.V., Kontich, Belgium). The scanned images were reconstructed and analyzed using SkyScan CT Analyzer (Skyscan). The structural parameters including trabecular bone volume per tissue volume, thickness, separation, and number were measured in the distal femoral metaphysis between 0.54 and 1.46 mm distal to the growth plate. Bone resorption assay Primary pre-osteoblasts were obtained from calvariae of newborn ICR mice (Orient Bio Inc.) by a sequential enzymatic digestion method described previously [25]. To obtain mature osteoclasts, bone marrow cells (1.5 × 107 cells) and pre-osteoblasts (1.5 × 106 cells) were cocultured in the presence of 1α,25-dihydroxyvitamin D3 (10 nM) and prostaglandin E2 (100 nM) in a 10-cm dish coated with collagen gel (Cellmatrix type I-A, Nitta Gelatin Inc., Osaka, Japan) for 6 days. The plates were treated with collagenase (Sigma-Aldrich), and mature osteoclasts were placed on an Osteo Assay Surface plate (Corning Inc., Corning, NY, USA), allowed to settle for 2 h, and then cultured with or without WEAO. After 24 h of culture, cells were stained for TRAP activity. Resorption pits by osteoclasts were photographed and analyzed by using ImageJ software, after removing cells with sodium hypochlorite. Quantitative real-time polymerase chain reaction (qPCR) analysis Total RNA was extracted with RNA-spin total RNA Extraction Kit (Bioneer, Daejeon, Korea), and fist-strand cDNA was synthesized from 1 μg of total RNA with AccuPower RT-PreMix (Bioneer). SYBR green-based qPCR was performed on the Applied Biosystems 7500 Real-Time PCR System (Foster City, CA, USA) with cDNA diluted to 1:5, 10 pmol of primers, and AccuPower GreenStar qPCR Master Mix (Bioneer). The following mouse-specific primer sets were used: c-Fos, 5′-CGGGTTTCAACGCCGACTAC-3′ (forward) and 5′-AAAGTTGGCACTAGAGACGGACAGA-3′ (reverse); NFATc1, 5′-CCGTTGCTTCCAGAAAATAACA-3′ (forward) and 5′-TGTGGGATGTGAACTCGGAA-3′ (reverse); Id2, 5′-CGGTGAGGTCCGTTAGGAAAA-3′ (forward) and 5′-CATGTTGTAGAGCAGACTCATCG-3′ (reverse); MafB, 5′-AGTGTGGAGGACCGCTTCTCTG-3′ (forward) and 5′-CTGGACGCGTTTATACCTGC-3′ (reverse); hypoxanthine phosphoribosyltransferase, 5′-CCTAAGATGAGCGCAAGTTGAA-3′ (forward) and 5′-CCACAGGACTAGAACACCTGCTAA-3′ (reverse). All reactions were run in triplicate, and data were analyzed using the 2-ΔΔCT method. Hypoxanthine phosphoribosyltransferase was used as an internal control. Western blot analysis Cells were washed with ice-cold PBS and lysed with RIPA buffer (Millipore, Temecula, CA, USA) supplemented with protease-inhibitor and phosphatase-inhibitor cocktail tablets (Roche Applied Science, Indianapolis, IL, USA) on ice for 30 min. The cell extracts were centrifuged at 10,000 g, 4°C for 10 min. Equal amounts of proteins (30 μg) were boiled in sodium dodecyl sulfate (SDS) sample buffer for 5 min and separated by 10% SDS-polyacrylamide gel electrophoresis and transferred to a polyvinylidene fluoride membrane (GE Healthcare, Buckinghamshire, UK). After blocking with 5% nonfat dry milk, the membranes were probed with the indicated primary antibodies, followed by secondary antibodies conjugated with horseradish peroxidase. Immunoreactive bands were visualized with SuperSignal West Femto Maximum Sensitivity Substrate (Thermo Fisher Scientific Inc., Rockford, IL, USA) using Luminescent Image Analyzer LAS-4000 (Fuji Photo Film Co., Tokyo, Japan). Retroviral gene transduction Retrovirus packaging and BMM infection by using retroviral vectors pMX-IRES-green fluorescent protein (GFP) and pMX-constitutively active (CA)-NFATc1-IRES-GFP were performed as described previously [24]. In brief, retrovirus packaging was performed by transient transfection of these pMX vectors into Plat-E retroviral packaging cells (Cell Biolabs, San Diego, CA, USA). BMMs were incubated with the viral supernatant from Plat-E cells together with polybrene (6 μg/mL, Sigma-Aldrich) and M-CSF (60 ng/mL) for 12 h. After removing viral supernatant, BMMs were cultured in the presence of M-CSF for 1 day and then treated as indicated. Statistical analysis Values are presented as mean ± SD in in vitro study and mean ± SEM in in vivo study. Two-group comparisons were performed with Student's t tests, while multiple-group comparisons were performed with analysis of variance followed by Dunnett’s test. A p-value less than 0.05 was considered statistically significant. Results and discussion WEAO inhibits RANKL-induced osteoclast differentiation To determine whether WEAO affects osteoclast differentiation, we examined the effect of WEAO on RANKL-induced osteoclast differentiation from its precursor cells, BMMs. Treatment of BMMs with M-CSF and RANKL for 4 days induced TRAP-positive multinucleated osteoclasts. When WEAO was added to the BMM cultures simultaneously with RANKL, osteoclast differentiation was inhibited by WEAO in a dose-dependent manner (Figure 1A and B). WEAO did not affect the viability of BMMs at concentrations less than 160 μg/mL (Figure 1C), indicating that the inhibitory effect of WEAO on osteoclast differentiation did not result from cytotoxicity. WEAO at 80 μg/mL almost completely inhibited osteoclast differentiation, without affecting cell viability. Thus, 80 μg/mL of WEAO was used for the subsequent experiments to elucidate the mechanisms underlying its anti-osteoclastogenic effect. To determine at which stage WEAO inhibits osteoclast differentiation, WEAO was added to the BMM cultures on days 0–3. WEAO effectively inhibited RANKL-induced osteoclast differentiation when added simultaneously with RANKL (day 0). In contrast, WEAO did not affect RANKL-induced osteoclast differentiation when added on days 2 and 3 (Figure 1D). These results suggest that WEAO inhibits early cellular events for RANKL-induced osteoclastogenesis. Effect of WEAO on RANKL-induced osteoclast differentiation in BMMs. (A, B) BMMs were cultured with vehicle (distilled water) or WEAO (10–160 μg/mL) in the presence of M-CSF (60 ng/mL) and RANKL (100 ng/mL) for 4 days. (A) Cells were fixed and stained for TRAP activity. Scale bar, 200 μm. (B) The number of osteoclasts (Oc) was counted. (C) The viability of BMMs was determined by Cell Counting Kit-8 assay. (D) BMMs were cultured in the presence of M-CSF and RANKL for 4 days, and WEAO (80 μg/mL) was added to the BMM cultures at the indicated days. The number of osteoclasts was counted on day 4. (E) HPLC chromatograms of WEAO and a standard mixture of chrysin, tectochrysin, and nootkatone at 203 nm. (F) BMMs were cultured with vehicle (dimethylsulfoxide) or nootkatone (10–40 μM) in the presence of M-CSF and RANKL for 4 days, and the number of osteoclasts was counted. (G) The effect of nootkatone on viability of BMMs. *p < 0.05; **p < 0.01 versus vehicle-treated control. Previous phytochemical studies have shown that flavonoids (e.g., tectochrysin and chrysin), diarylheptanoids (e.g., yakuchinone A and yakuchinone B), and sesquiterpenes (e.g., nootkatone) are abundant in ethanol extracts of the fruits of A. oxyphylla[17, 26]. In accordance with this, we identified chrysin, tectochrysin, and nootkatone in 75% ethanol extract of the fruits of A. oxyphylla HPLC analysis, based on their HPLC retention times and UV absorption spectra (data not shown). Among these compounds, nootkatone was relatively abundant in WEAO (Figure 1E). Nootkatone has been shown to have multiple pharmacological properties including anti-inflammatory [27], anti-allergic [28], antiplatelet [29], and anti-obesity [30] activities. We found that nootkatone (10–40 μM) dose-dependently inhibits RANKL-induced osteoclast differentiation without affecting cell viability (Figure 1F and G). Although further study is needed to isolate and characterize the chemical constituents of WEAO, our results suggest that nootkatone might be one of the active constituents contributing to the inhibitory effect of WEAO on osteoclast differentiation. WEAO inhibits RANKL-induced NFATc1 expression in osteoclast precursors We next investigated the effect of WEAO on the expression of transcription factors regulating osteoclast differentiation. RANKL stimulated the mRNA and protein expression of NFATc1 in BMMs, and WEAO blunted RANKL-induced NFATc1 expression (Figure 2A and B). To investigate whether the reduction of NFATc1 is responsible for the anti-osteoclastogenic action of WEAO, BMMs were transduced with retroviruses harboring control GFP or CA-NFATc1-GFP vectors. WEAO blocked RANKL-induced osteoclast differentiation in BMMs infected with control GFP, whereas the ectopic expression of CA-NFATc1 rescued the inhibitory effect of WEAO (Figure 2C). These results suggest the involvement of NFATc1 in the anti-osteoclastogenic effect of WEAO and further confirmed that the anti-osteoclastogenic effect of WEAO is not due to cytotoxicity. Effect of WEAO on the gene expression of transcription factors involved in osteoclast differentiation. (A, B) BMMs were cultured with vehicle (distilled water) or WEAO (80 μg/mL) in the presence of M-CSF (60 ng/mL). Total RNA and cell lysates were obtained following stimulation with RANKL (100 ng/mL) for the indicated times. (A) Relative mRNA expression levels of NFATc1, c-Fos, Id2, and MafB were determined by qPCR. **p < 0.01 versus vehicle-treated control. (B) Total cell lysates were subjected to Western blot analysis with antibodies against NFATc1, c-Fos, and p38. p38 was used as a loading control. (C) BMMs transduced with retroviruses expressing either pMX-IRES-GFP (pMX) or pMX-CA-NFATc1-IRES-GFP (pMX-CA-NFATc1) were cultured with vehicle or WEAO (80 μg/mL) in the presence of M-CSF (60 ng/mL) and RANKL (100 ng/ml) for 4 days. The number of osteoclasts (Oc) was counted. **p < 0.01. The transcription factor c-Fos is also essential for osteoclastogenesis and functions as a key upstream activator of NFATc1 during osteoclastogenesis [31]. Similar to its effect on NFATc1 expression, WEAO abrogated RANKL-induced c-Fos mRNA and protein expression (Figure 2A and B). In addition to up-regulation of transcriptional activators, RANKL stimulates NFATc1 expression and osteoclastogenesis by suppression of several transcriptional repressors including Ids and MafB [13]. The expression of Id helix-loop-helix transcription factors is suppressed by RANKL during osteoclastogenesis, and Ids negatively regulate RANKL-induced osteoclastogenesis by down-regulating the expression of osteoclast-associated receptor and NFATc1 through attenuation of DNA binding ability of Mitf [32]. MafB expression is also down-regulated by RANKL, and MafB suppresses osteoclastogenesis by interfering with transcriptional activities of c-Fos, Mitf, and NFATc1 [33]. Consistent with the previous reports, RANKL markedly reduced the expression of Id2 and MafB in BMMs. WEAO increased Id2 expression and inhibited RANKL-induced down-regulation of Id2 and MafB expression (Figure 2A). It has been shown that Id2 and MafB do not affect RANKL-induced c-Fos expression [33, 34]. Thus, these results collectively suggest that WEAO inhibits RANKL-induced NFATc1 expression by suppressing the induction of its up-stream activator c-Fos as well as the down-regulation of its negative regulators, Id2 and MafB, thereby inhibiting osteoclastogenesis. WEAO alters RANKL-induced activation of MAPKs and NF-κB Binding of RANKL to RANK leads to the activation of MAPK and NF-κB pathways, which are implicated in osteoclast differentiation by involving c-Fos and NFATc1 induction [7–9, 35, 36]. To get more insights into the mechanisms underlying the anti-osteoclastogenic effect of WEAO, we investigated whether WEAO affects the early signaling events trigged by RANKL. Treatment of BMMs with RANKL increased the phosphorylation of JNK and p38 MAPKs within 5 min, reached the maximum at 15 min, and then decreased thereafter (Figure 3). Pretreatment of BMMs with WEAO increased the phosphorylation of JNK and p38 and prolonged RANKL-induced phosphorylation of JNK and p38. RANKL stimulated the classical NF-κB signaling pathway, determined by IκBα phosphorylation and subsequent degradation. Pretreatment of BMMs with WEAO increased IκBα phosphorylation but markedly suppressed RANKL-induced IκBα phosphorylation and degradation (Figure 3). Thus, these results suggest that WEAO inhibits RANKL-induced c-Fos induction, at least in part, by suppressing the classical NF-κB signaling pathway. It has been reported that RANKL down-regulates MafB expression through JNK and p38 MAPK pathways but not the classical NF-κB pathway [33]. Thus, our results suggest that WEAO inhibits RANKL-mediated MafB down-regulation independently of these MAPK pathways. However, the mechanisms underlying the inhibitory effects of WEAO on RANKL-mediated down-regulation of MafB and Id2 remain to be elucidated. WEAO does not affect bone resorbing activity of mature osteoclasts When attached to bone matrix, osteoclasts polarize their membrane to bone surface and secret hydrochloric acid and acidic proteases which degrade bone matrix in a sealed compartment [2]. To investigate whether WEAO affects resorbing activity of mature osteoclasts, mature osteoclasts were generated from the coculture of bone marrow cells and pre-osteoblasts and seeded on a plate coated with an inorganic crystalline calcium phosphate designed to mimic bone mineral. After 24 h of culture, numerous pits resorbed by osteoclasts were formed on the plate. WEAO did not affect osteoclast number and the resorbed area at 20–80 μg/mL (Figure 4A–C), indicating that WEAO does not directly affect bone resorbing activity of mature osteoclasts. Effect of WEAO on bone resorbing activity of mature osteoclasts. Mature osteoclasts were seeded on a plate coated with an inorganic crystalline calcium phosphate and then cultured with vehicle or WEAO (20–80 μg/mL) for 24 h. (A) Cells were stained for TRAP activity, and resorption pits formed by osteoclasts were photographed. Scale bar, 200 μm. (B) The number of osteoclasts (Oc) was counted. n.s, not significant. (C) The total area of resorption pits was measured. WEAO inhibits RANKL-induced bone loss in vivo Increased RANKL activity is involved in bone destruction in various bone diseases [2]. Having found that WEAO inhibits RANKL-induced osteoclast differentiation in vitro, we next examined the in vivo effect of WEAO on osteoclast-mediated bone destruction using a murine model of bone loss by RANKL injection. Intraperitoneal injections of RANKL into mice rapidly induce bone loss by stimulating osteoclast differentiation and function [37]. RANKL injections caused a severe trabecular bone loss at the distal femoral metaphysis (Figure 5A). Quantitative micro-CT analysis of trabecular bone microarchitecture showed that RANKL injections led to a marked decrease in trabecular bone volume per tissue volume, trabecular thickness, and trabecular number, with an increase in trabecular separation. Oral administration of WEAO (0.25 g/kg twice daily) significantly attenuated RANKL-induced changes in trabecular bone microarchitecture, except trabecular thickness (Figure 5A and B). We next investigated the changes in serum TRAP 5b activity, CTX levels, and osteocalcin levels, which are used for markers of osteoclast numbers, bone resorption, and bone formation, respectively [38]. WEAO markedly inhibited the increases in serum TRAP 5b activity and CTX levels induced by RANKL injections (Figure 5C and D). There were no significant differences in serum osteocalcin levels among the groups (Figure 5E). Therefore, it is likely that the protective effect of WEAO against bone destruction is mainly due to suppression of bone resorption through inhibition of osteoclast differentiation. Our results clearly showed that WEAO at a dose of 0.25 g/kg twice daily attenuates RANKL-induced osteoclast differentiation and bone destruction in vivo. However, such beneficial effects of WEAO were not observed at a dose of 0.75 g/kg (data not shown). Therefore, further studies are needed to more thoroughly characterize the dose response effects of WEAO on bone metabolism. In addition, the beneficial effect of WEAO in bone disease states such as postmenopausal osteoporosis and lytic bone metastasis remains to be investigated. Effect of WEAO on RANKL-induced bone destruction in mice. Mice were orally administrated with vehicle (n = 8 per group) or WEAO (0.25 g/kg, n = 7) twice daily for 5 days, and RANKL (1 mg/kg) was injected intraperitoneally on days 3 and 4. Blood serum and right femur were collected on day 6. (A) Representative micro- CT images of the distal femurs from each group. (B) Quantitative micro- CT analysis of trabecular bone volume/tissue volume (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp) in the distal femoral metaphysis. (C) Serum TRAP 5b activity. (D) Serum CTX levels. (E) Serum osteocalcin levels. *p < 0.05; **p < 0.01; ***p < 0.001; n.s, not significant. Conclusions This study demonstrated that WEAO inhibits osteoclast differentiation by suppressing RANKL-induced NFATc1 expression in osteoclast precursors. The reduction of NFATc1 expression by WEAO was attributable to suppression of RANKL-induced up-regulation of its positive regulators, NF-κB and c-Fos, and down-regulation of its negative regulators, Id2 and MafB. Consistent with the in vitro results, oral administration of WEAO attenuated RANKL-induced bone destruction by inhibiting osteoclast differentiation. Given the role of excessive RANKL activity in pathological bone loss, our findings suggest that WEAO may be useful for the prevention and treatment of bone metabolic diseases associated with excessive osteoclastic bone resorption. References - 1. Negishi-Koga T, Takayanagi H: Ca2 + −NFATc1 signaling is an essential axis of osteoclast differentiation. Immunol Rev. 2009, 231: 241-256. 10.1111/j.1600-065X.2009.00821.x. - 2.. - 3.. - 4.. - 5.. - 6.. 10.1172/JCI116179. - 7.. 10.1172/JCI200419657. - 8. Huang H, Chang EJ, Ryu J, Lee ZH, Lee Y, Kim HH: Induction of c-Fos and NFATc1 during RANKL-stimulated osteoclast differentiation is mediated by the p38 signaling pathway. Biochem Biophys Res Commun. 2006, 351: 99-105. 10.1016/j.bbrc.2006.10.011. - 9.. 10.1074/jbc.M610701200. - 10. Gohda J, Akiyama T, Koga T, Takayanagi H, Tanaka S, Inoue J: RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis. 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Molecules. 2013, 18: 7376-7388. 10.3390/molecules18077376. - 24. Lee JH, Kim HN, Yang D, Jung K, Kim HM, Kim HH, Ha H, Lee ZH: Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling. J Biol Chem. 2009, 284: 13725-13734. 10.1074/jbc.M806941200. - 25.. - 26. Li YH, Chen F, Wang JF, Wang Y, Zhang JQ, Guo T: Analysis of nine compounds from Alpinia oxyphylla fruit at different harvest time using UFLC-MS/MS and an extraction method optimized by orthogonal design. Chem Cent J. 2013, 7: 134-10.1186/1752-153X-7-134. - 27. Tsoyi K, Jang HJ, Lee YS, Kim YM, Kim HJ, Seo HG, Lee JH, Kwak JH, Lee DU, Chang KC: (+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction. J Ethnopharmacol. 2011, 137: 1311-1317. 10.1016/j.jep.2011.07.062. - 28. Jin JH, Lee DU, Kim YS, Kim HP: Anti-allergic activity of sesquiterpenes from the rhizomes of Cyperus rotundus. Arch Pharm Res. 2011, 34: 223-228. 10.1007/s12272-011-0207-z. - 29. Seo EJ, Lee DU, Kwak JH, Lee SM, Kim YS, Jung YS: Antiplatelet effects of Cyperus rotundus and its component (+)-nootkatone. J Ethnopharmacol. 2011, 135: 48-54. 10.1016/j.jep.2011.02.025. - 30. Murase T, Misawa K, Haramizu S, Minegishi Y, Hase T: Nootkatone, a characteristic constituent of grapefruit, stimulates energy metabolism and prevents diet-induced obesity by activating AMPK. Am J Physiol Endocrinol Metab. 2010, 299: E266-E275. - 31.. 10.1074/jbc.M313973200. - 32.. - 33.. - 34. Oh J, Lee MS, Yeon JT, Choi SW, Kim HS, Shim H, Lee SY, Youn BS, Yokota Y, Kim JH, Kwak HB: Inhibitory regulation of osteoclast differentiation by interleukin-3 via regulation of c-Fos and Id protein expression. J Cell Physiol. 2012, 227: 1851-1860. 10.1002/jcp.22913. - 35. Lee JH, Jin H, Shim HE, Kim HN, Ha H, Lee ZH: Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-kappaB signal. Mol Pharmacol. 2010, 77: 17-25. 10.1124/mol.109.057877. - 36.. - 37.. - 38. Naylor K, Eastell R: Bone turnover markers: use in osteoporosis. Nat Rev Rheumatol. 2012, 8: 379-389. 10.1038/nrrheum.2012.86. Pre-publication history The pre-publication history for this paper can be accessed here: Acknowledgements This work was supported by a grant (K14050) from the Korea Institute of Oriental Medicine, Ministry of Science, ICT and Future Planning, Republic of Korea. Additional information Competing interests The authors declare that they have no competing interests. Authors’ contributions HH designed the experiments and wrote the manuscript. HH, KSS, TK, and CJL carried out the experiments and analyzed the data. JHP and HSK participated in micro-CT analysis. JYM supervised the study and participated in the design of the study, H., Shim, KS., Kim, T. et al. Water extract of the fruits of Alpinia oxyphylla inhibits osteoclast differentiation and bone loss. BMC Complement Altern Med 14, 352 (2014). Received: Accepted: Published: DOI: Keywords - Osteoclast - Alpinia oxyphylla - RANKL - Bone loss
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\section{Introduction} Similar to \textit{baits} that fishermen use to catch fish, clickbaits aim to catch the readers by getting their attention with an appealing title. These titles intent to spark the curiosity of the readers such that they want to follow the link. The following titles are good examples of clickbaits: \begin{itemize} \item Man tries to hug a lion. You won't believe what happens next! \item 21 celebrities who ruined their faces with plastic surgeries \item 15 hilarious tweets of stupid people \end{itemize} However, making the reader click the link and then displaying advertisements is often the sole purpose of the clickbaits~-- and the quality of the content is secondary for the publishers. The curiosity is usually not satisfied and the reader leaves the website. Social media websites such as Twitter or Facebook contain a large amount of clickbaits. It is possible to save the time of the readers by detecting if a title is clickbaiting and warning them, or even hiding the link altogether. This was the motivation of the clickbait challenge (\url{http://www.clickbait-challenge.org/}): the organizers invited participants to develop a machine learning model for predicting if a post on social media is a clickbait. They prepared a large dataset of posts from Twitter with each post labeled as clickbaiting or not. \subsection{Related Work} It is not the first time the research community is concerned with the problem of detecting clickbaits. It is believed that Facebook downscores clickbaits in the user feeds, but there are no publications on their approach, only an announcement on their newsroom blog\footnote{\url{https://newsroom.fb.com/news/2014/08/news-feed-fyi-click-baiting/}}. Use of Machine Learning to treat this problem was first reported by Potthast and others \cite{potthast:2016}, who collected a corpus of posts from Twitter and used crowdsourcing to annotate them. To discover if their results can be improved, the same researches later organized the present challenge~-- the clickbait challenge \cite{potthast:2017a} on the TIRA platform \cite{potthast:2014}. In addition to the previous dataset, they gathered more data and released a significantly larger corpus of annotated posts from Twitter \cite{potthast:2017b}. \section{Dataset and Challenge Description} The provided dataset contains posts from a social media platform ``Twitter''. This platform is often used by content providers to publish the links to their websites. Each post, ``tweet'', is a short message (up to 140 characters), which can be accompanied by a link and a picture. This is the information collected by the organizers: the content of each tweet, the link and the picture it contains. Each post is provided as a JSON object. For example: \begin{verbatim} { "id": "608999590243741697", "postTimestamp": "Thu Jun 11 14:09:51 2015", "postText": ["Some people are such food snobs"], "postMedia": ["608999590243741697.png"], "targetTitle": "Some people are such food snobs", "targetDescription": "You'll never guess one...", "targetKeywords": "food, foodfront, food waste...", "targetParagraphs": [ "What a drag it is, eating kale ...", "A new study, published this ...", "..." ], "targetCaptions": ["(Flikr/USDA)"] } \end{verbatim} The following information is available for each tweet: \begin{itemize} \item \verb|postText|: the content of the tweet, \item \verb|postMedia|: the image that was posted alongside with the tweet (also made available by the organizers), \item \verb|targetTitle|: the title of the actual article, \item \verb|targetDescription| and \verb|targetKeywords|: the description and keywords from the meta tags of the article, \item \verb|targetParagraphs|: the actual content of the article, \item \verb|targetCaptions|: all captions in the article. \end{itemize} \begin{figure} \centering \includegraphics[width=\columnwidth]{selection_002.png} \caption{The design of the task evaluation. The screenshot is taken from \protect\url{http://clickbait-challenge.org/}.} \label{fig:eval-design} \end{figure} Each post is then assigned a ``clickbaitness'' score by human evaluators . It was possible to assign the post one of the following options (see fig.~\ref{fig:eval-design}): \begin{itemize} \item not click baiting (0.0), \item slightly click baiting (0.33), \item considerably click baiting (0.66), \item heavily click baiting (1.0). \end{itemize} Multiple people evaluated each post, and all the responses were saved. For example, the post titled ``Apples' iOS 9 `App thinning' feature will give your phone's storage a boost'' was evaluated by five people and the following scores were obtained: \begin{itemize} \item 0.00 -- 3 times, \item 0.33 -- once, \item 0.66 -- once. \end{itemize} Then the mean score was calculated, which is 0.2 for this post. This score indicates that the post not clickbaiting. This is the target variable the contestants should predict: the mean clickbaitness score of each post. The solutions then were evaluated by Root Mean Squared metric~-- a common metric for evaluating regression models. \begin{table} \centering \begin{tabular}{|c|c|c|c|} \hline \textbf{Dataset} & \textbf{Posts} & \textbf{Clickbaits} & \textbf{Not Clickbaits} \\ \hline Training & 2495 & 762 & 1697 \\ Validation & 19538 & 4761 & 14777 \\ Unlabeled & 80012 & n/a & n/a \\ Testing & ? & ? & ? \\ \hline \end{tabular} \caption{The datasets provided by the organizers.} \label{tab:data} \end{table} Two labeled datasets were provided by the organizers: first, the dataset from the original work by Potthast et al \cite{potthast:2016} with 2,495 posts: 762 clickbaits and 1,697 not clickbaits. When the competition was already in progress, the second dataset was released: it contained 19,538 posts with 4,761 clickbaits and 14,777 not clickbaits \cite{potthast:2017b}. The third labeled dataset was not provided: it was used for evaluating the models of the contestants. In addition to the labeled dataset, another set of approximately 80,000 tweets was available for use. The records in this dataset followed the same format, but no ground truth labels were collected for these posts (see table~\ref{tab:data}). Finally, the contestants were free to use any external data source. \section{Approach} In this section we present our approach to the challenge in details. First, we describe the hardware and software used for the solution, then talk about external datasets we used for the challenge. After that we describe the features we extracted from the challenge dataset as well as the models built on these features. \subsection{Environment} The experiments were performed on a Linux Ubuntu server with 32GB RAM and 8 Cores. We used Python 3.4 and the PyData stack for our development: \begin{itemize} \item \texttt{numpy} 1.12.1 for numerical operations \cite{van2011numpy}; \item \texttt{scipy} 0.19.0 for storing sparse data matrices \cite{jones2015scipy}; \item \texttt{pandas} 0.18.1 for tabular data manipulation \cite{mckinney2014pandas}; \item \texttt{nltk} 3.2.1 for text manipulation \cite{bird2006nltk}, \item \texttt{scikit-learn} 0.18.1 for data preprocessing and machine learning \cite{pedregosa2011scikit}. \end{itemize} We used Anaconda --~a distribution of Python with many scientific libraries pre-installed\footnote{\url{https://www.continuum.io/downloads}}, including all the aforementioned libraries. \subsection{External Data} In the competition the participants were allowed to use any external data source. The provided labelled datasets are not very large, which is why we decided to obtain additional data: we believed that it should help improve the quality of the resulting models. To obtain this additional data, we used the approach described in the post ``Identifying Clickbaits Using Machine Learning'' by A.~Thakur\footnote{\url{https://www.linkedin.com/pulse/identifying-clickbaits-using-machine-learning-abhishek-thakur/}}. Namely, we identified multiple Facebook groups that contained mostly clickbaiting posts, and used the information there as positive labeled training instances. Likewise, we picked up multiple groups with news which we deemed not clickbaiting and assigned them the negative label. To retrieve the information from Facebook we used the Facebook scraper opensourced by M.~Wolf\footnote{\url{https://github.com/minimaxir/facebook-page-post-scraper}}. This way we obtained the content of the following Facebook groups: \begin{itemize} \item clickbaiting (88.7k posts): \begin{itemize} \item buzzfeed (42.8k posts), \item clickhole (14k posts), \item upworthy (30k posts), \item StopClickBaitOfficial (1.9k posts). \end{itemize} \item not clickbaiting (154.9k posts): \begin{itemize} \item CNN (65.7k posts), \item Wikinews (2.8k posts), \item NYTimes (86.4k posts). \end{itemize} \end{itemize} In total we collected approximately 244.5k posts, and around 40\% of them were clickbaiting. A similar approach was used by the author when developing a clickbait detection model at Searchmetrics, a company that is doing Search Engine Optimization. \subsection{Modeling} \textbf{Data Preparation and Features} Each post in the provided dataset contains multiple text fields and a picture. Before using the text fields in the modeling, we applied to them the following preprocessing procedure: \begin{itemize} \item remove repeating sentences, \item remove HTML tags like \verb|<i>|, \verb|<b>| and so on, \item remove English stop words, \item extract the stem of each word with a Porter stemmer \cite{Manning2008IIR}, \item replace each number with a special token ``\verb|[n]|'', \end{itemize} The same preprocessing procedure was applied to the external dataset from Facebook. Then we used the standard Bag-of-Words approach to encode the textual information into a vector space \cite{Manning2008IIR}. In additional to single tokens we also used 2- and 3-grams to capture the sequential nature of the textual data. We decided not to use image data as it seemed quite difficult and we believed it would not provide a significant improvement over the text-only solution. \ \\ \textbf{Machine Learning models} Our approach to the challenge was to train multiple linear models and then combine them with a tree-based model. For model selection and validation we used the 5-fold cross-validation scheme, and the tables below report the mean score across all 5 folds. \begin{table} \centering \begin{tabular}{|c|c|c|c|} \hline \textbf{Feature} & \textbf{MSE} & \textbf{Time, s} & \textbf{Best $C$} \\ \hline \verb|postText| & 0.039 & 1.7 & 0.1 \\ \verb|targetKeywords| & 0.060 & 1.3 & 0.5 \\ \verb|targetDescription| & 0.054 & 1.02 & 0.005 \\ \verb|targetCaption| & 0.053 & 1.7 & 0.001 \\ \verb|targetParagraphs| & 0.044 & 12.6 & 0.001 \\ \verb|targetTitle| & 0.047 & 1.7 & 0.01 \\ all concatenated & 0.042 & 16.3 & 0.001 \\ \hline \end{tabular} \caption{The performance of individual \texttt{LinearSVR} models for predicting the mean.} \label{tab:ind-mse} \end{table} \begin{table} \centering \begin{tabular}{|c|c|c|c|} \hline \textbf{Feature} & \textbf{MSE} & \textbf{Time, s} & \textbf{Best $C$} \\ \hline \verb|postText| & 0.014 & 0.7 & 0.01 \\ \verb|targetKeywords| & 0.014 & 0.3 & 0.01 \\ \verb|targetDescription| & 0.014 & 0.9 & 0.005 \\ \verb|targetCaption| & 0.014 & 2.0 & 0.001 \\ \verb|targetParagraphs| & 0.015 & 11.5 & 0.001 \\ \verb|targetTitle| & 0.014 & 1.0 & 0.01 \\ all concatenated & 0.015 & 14.6 & 0.001 \\ \hline \end{tabular} \caption{The performance of individual \texttt{LinearSVR} models for predicting the standard deviation.} \label{tab:ind-std} \end{table} For each text feature we trained an SVM regression model with a linear kernel (\verb|LinearSVR| from scikit-learn, which is based on the LIBLINEAR library \cite{fan2008liblinear}). These sets of models were trained to predict the mean clickbaitness score of each post. The performance of each feature is reported in the table~\ref{tab:ind-mse}. The best performing individual model is the model based on the post text~-- the actual message written on twitter. This model achieves 0.039 MSE on cross-validation. Since our model is linear, it is possible to look at the coefficients to discover what are the strongest indicators of clickbaitness. For example, the following are the top 10 features with the largest positive weight (note that the tokens are stemmed): \begin{itemize} \item \verb|[n] pictur| \item \verb|[n] thing| \item \verb|[n] artist| \item \verb|[n] way| \item \verb|[n] celebr| \item \verb|here come| \item \verb|shocker| \item \verb|whoa| \item \verb|[n] meme| \item \verb|wat| \end{itemize} This suggests that the numbers (the ``\verb|[n]|'' token) in the post is a very good sign that the post is clickbaiting. In addition to that we trained another set of models which were used to predict the standard deviation of clickbaitness for each post (see table~\ref{tab:ind-std}). For this target all features performed similarly achieving around 0.014 MSE. Lastly, we trained a binary classification model on our external data. For that we used SVM with a linear kernel, \verb|LinearSVC| from scikit-learn, based on the LIBLINEAR library \cite{fan2008liblinear}. To evaluate the performance there we used a hold-out dataset, and obtained AUC of 95\%. The trained model was then applied to the textual fields of the competition dataset, and the output was used an a set of additional features. \ \\ \textbf{Ensembling} After training individual models we combined them using stacking \cite{wolpert1992stacked}: the output of these models was used as input to another second-level model. The individual linear models were stacked using Extremely Randomized Trees \cite{geurts2006extremely} (\verb|ExtraTreeRegressor| in scikit-learn)~-- a variation of the Random Forest model that works especially good for stacking because it rarely overfits. \begin{table} \centering \begin{tabular}{|c|c|c|c|} \hline \textbf{Features} & \textbf{MSE} \\ \hline Mean only & 0.0331 \\ Mean + Facebook & 0.0327 \\ Mean + std & 0.0326 \\ Mean + std + Facebook & 0.0326 \\ \hline \end{tabular} \caption{The performance of the ensemble models.} \label{tab:ensembles} \end{table} We trained the ensemble on different feature subsets, and established that the model that uses only mean and standard deviation features was the best one. The model that also used the extra data from Facebook achieved the same performance, which is why we decided to use the simpler model without the Facebook features (see table~\ref{tab:ensembles}). \begin{table} \centering \begin{tabular}{|c|c|c|c|} \hline \textbf{Feature} & \textbf{Importance} \\ \hline \verb|postText| mean & 0.32 \\ all concatenated mean & 0.29 \\ \verb|targetTitle| mean & 0.15 \\ \verb|postText| std & 0.08 \\ \verb|targetKeywords| mean & 0.07 \\ \verb|targetTitle| std & 0.02 \\ all concatenated std & 0.02 \\ \verb|targetKeywords| std & 0.01 \\ \hline \end{tabular} \caption{Feature importance: fraction of times the feature was used for a split in the tree.} \label{tab:importance} \end{table} According to the output of the ExtraTree model, the most important feature is the \verb|postText| model for predicting the mean, which is not surprising, since it is best performing single model (see table~\ref{tab:importance}). \section{Evaluation Results} For the final evaluation we selected the best performing mean+std model and executed it against the withheld testing data on the TIRA platform. \begin{table} \centering \begin{tabular}{|c|c|c|} \hline \textbf{Team name} & \textbf{MSE} & \textbf{Running Time} \\ \hline zingel & 0.0332 & 00:03:27 \\ emperor & 0.0359 & 00:04:03 \\ \textbf{carpetshark} & 0.0362 & 00:08:05 \\ arowana & 0.0390 & 00:35:24 \\ pineapplefish & 0.0413 & 00:54:28 \\ \hline \end{tabular} \caption{Top 5 participants of the challenge.} \label{tab:final-standings} \end{table} Our approach took the 3rd position with 0.0362 MSE on the testing dataset (see table~\ref{tab:final-standings}). \section{Conclusion} In this paper we approach the problem of identifying clickbaiting posts on social media. We show how to address the challenge with a small ensemble of linear models, and we conclude that the results are competitive: our model ranked high on the final standing. \begin{raggedright}
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Title: Caused terrible diarrhea in both my 11 year old labs Review: My labs are 100 lbs each. After only 2 chewable tablets within a 12 hr period, they both developed violent diarrhea. I stopped it immediately. My poor dogs were in so much distress and it stressed all of us. I had to leave the dog door in overnight the second night so that I would not have to wake up to what I did the first night. Might be a good product for some dogs but just be aware that this can happen. Believe me, it is not how you or your senior dog wants to spend a weekend. Is this product review negative? Answer: Yes
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Norwegian paper publishes anti-Semitic cartoonNorwegian paper’s cartoon suggests circumcision akin to pedophilia, insanity. Contact Editor JTA, 17/05/17 07:11 Definition of anti-SemitismiStock A Norwegian tabloid published a caricature equating Jewish and Muslim supporters of non-medical circumcision with insane pedophiles.-pronged Norwegian Center against Racism condemned the paper over the 2013 cartoon, stating.. Tags:Anti-Semitism, Circumcision, Norway, cartoons
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I’m nearly at the point in college where I don’t care anymore (can’t I just have my degree and go do field work, please?), and I would much rather read the latest issue of Nature or The Ancestor’s Tale than the textbook. Hence, this description from the “Summary of 99% of the people you will ever meet in college” fits perfectly;). If I actually tried I’m sure I would have a much higher GPA and very little time to read outside of class, but I’m happier with the way things are.
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I wanna see multiplayer so bad. I'm not even thinking competitive. Co-op would be absolutely stellar. Right now I'm conducting am experiment with friends. They just got me into the game and I have an idea: Designate Google.drive or dropbox as the save folder. Then we can play the same colony. It's still asynchronous, but if it works then it'll still be cool to know we're both guiding the colony into the future. I imagine doing my school, logging in on the weekend and seeing what highs and lows have befallen the settlers
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Set within its own garden featuring lush paths and relaxation areas, SPA Cenvaree presents a peaceful environment paired with a tempting selection of traditional therapies from Thai and Ayurvedic philosophies as well as modern rejuvenation practices. We went for full massages (kids included) on our second day at the resort. It was such a pleasant experience, that we made sure we went for another spa day before we left. This was my second stay at this resort and I still had fond memories of my previous visit so this time I booked myself in for the 3 day package. Each day my therapist, Ae, greeted me with the smiling... Visited the Cenvaree spa a few times and it was Blissful! Absolutely loved my massages at this spa! I had my own aromatherapy massage, aromatherapy massage at the same time as my daughter and also a 90 min signature 4 hands massage which was my... Stayed at the Centara Karon for 10 days over Christmas and New Year's and treated ourselves to the different spa offerings almost every day. The Salt Pot Muscle Melter was simply amazing, as was the...
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What goes through your mind on an early morning walk? For the first part of my morning ritual, my mind is pure chaos. The stream of consciousness chides, cajoles, threatens, and screams at me as I plod along. You didn’t need that bowl of ice cream last night! Get that house clean! Why can’t you stay on a schedule? What were you thinking? Why did you say that to him? And on and on . . . Interspersed with lectures from my other selves are words that I can’t forget: sharp words that hurt, rebukes, insults, and the like that should have been pushed back into the dusty closets of my mind. Instead, they echo as heavy backdrops of negativity. They weigh me down as I walk, translating physically by making my back and legs ache, my head throb. My walk becomes more like a wild boar crashing through than a graceful gazelle on the Serengeti. How does one find serenity? I know people who always seem calm and reasonable, a joy to be around. Even in the face of adversity, they can find silver linings. I tend to do the opposite. And when I consider what kind of a life I’ve had thus far, it hasn’t been that tough. Especially in comparison to others. “There’s always someone worse off,” my mother would say when I complained about most anything. And I know that now; in fact, I knew that then. Yet this compulsion to get down on myself, to torture myself by going over and over every real and perceived wrong is constant, no matter how often I beat it back. I stop at the little bridge to watch the rushing water, muddy and ever-changing. We’ve had some recent rains, and I can see where the creek had risen on its banks. A doe hesitantly ventures out from the trees, followed by twin fawns. They drink at the wide part of the creek, choosing to ignore me standing on the bridge. They know I’m not dangerous. Crazy, maybe, but not dangerous. I take a deep shuddering breath as if I had been holding it in. Tears hang like silver threads in the back of my head. I haven’t cried in ages and I’m not going to now. A sweet melody from a goldfinch trills across the valley. I hear a tree frog and splashing sounds as the deer run across the creek. I decide to go on with my walk and my life. My sneakered feet make a rhythmic pleasing sound on the trail. A truck passes on the road nearby, the first traffic I’ve noticed this morning. I meet a bicyclist who greets me with a good morning and a smile. The flora by the trail is fifty shades of green. Fifty Shades . . . I laugh at my own “literary” reference. The words in my head fade into a hum, and I pick up my step. I walk through a spider’s strand, brushing it off and breaking it. That poor spider worked a long time to get that strand just right to catch its breakfast, and I’ve gone and wrecked it. But what if it had caught me? A storyline partially forms in my mind. I’ll never reach serenity or Nirvana, but hey, I’m all right for now. OMP Admin Note: Michele Potter is a writer and OMP Network member – one of a group of networkers who will be blogging on a regular basis on various causes and issues. Michele is an incredibly diverse and talented writer who I hope will collect her short stories and make them available on Amazon someday soon. In the meantime, her story PERCEPTIONS is available in the guest author section of the flash fiction anthology BITE SIZE STORIES VOLUME ONE. One thought on “The Sounds of Silence ~~ by Michele Potter, #OMP Blogger”
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America is a nation of immigrants who brought with them music and dance, crafts and skills from their communities in the Old World. Although little in the way of material possessions may have been carried to their new homes by the immigrants, they carried in their minds and hearts other treasures: stories, ballads, dances, crafts and culinary customs. Some of these expressions have survived intact: in others, the new environment wrought changes in style, content or meaning. In the Old Ways in the New World area of the Festival each presentation was a celebration of shared ways as craftspeople, musicians and dancers from abroad and their American counterparts came together to carry on traditions particularly strong on festive occasions. Old Ways was concerned with the presentation of elements of group identity. Here the point of focus was the cultural baggage that newcomers - early and late, forced and willing - brought to North America and creatively used in maintaining their unique sense of community. These traditions serve to reinforce, reassure and stabilize people struggling to survive in an unaccustomed environment. The 1974 Festival feature three programs: Scandinavians and Scandinavian Americans, Tunisians and Tunisian Canadians, and Greeks and Greek Americans. The Scandinavian fiddle tradition was the foundation on which the Scandinavian presentation was based. A traditional fiddlers' procession was one of the highlights of the area daily (July 3-7). The fiddle is played as a solo instrument, in concert with other fiddles or other instruments, and as the accompaniment for folk and old time dancing. Norwegian folksongs and singing games and Swedish immigrant songs. All music and dancing events took place on the Scandinavian stage or in the informal stage in the kaffestova, the Norwegian coffee shop. Finnish, as well as Swedish and Norwegian cooking were demonstrated. Festival visitors could join Tunisians from the Old and New Worlds in celebrating folk traditions that afford them a common cultural identity. Participants in the Tunisian presentation included thirty musicians and dancers, as well as craftspeople from Tunis and the SahiI, and twenty emigrants from these regions who now live in Montreal, Quebec. The program featured a variety of musical traditions, some associated with specific social activities and some associated with specific regions of Tunisia. Tunisian food added to the festivities. In the Tunisian crafts tent, artisans gave continuous demonstrations of four traditional crafts that thrive in Tunisia: carpet weaving, musical instrument making, metal smithery, and embroidery on heavy canvas. Musicians, dancers and singers from two culturally distinct Greek communities, the Pontic and the Karpathian, met their American counterparts on the Mall during the second week of the Old Ways in the New World program. Pontic traditions were represented by performers from Northern Greece and the greater New York area. Karpathians from Baltimore, New York City and Vancouver presented their traditions along with relatives and friends from the islands of Karpathos and Rhodes and the port of Athens. The kafeneion, or cafe, is the center of all social activity in the Greek community. Thematic workshops were held at the kafeneion; topics for discussion and demonstration included comparative musical forms, music, song and dance traditions as related to the life cycle, backgammon instruction as well as song and dance workshops. A special feature of this program was the glendi, the community celebration of feasting, music-making and dancing observed at all festive occasions. The Old Ways in the New World program was coordinated by Shirley Cherkasky, assisted by Carla Borden and Suzanne Cox. An advisory group included Conrad Arensberg, Svatava Pirkova Jakobson, Alan Lomax, and David McAIIester. Major sponsors included the American Revolution Bicentennial Administration, the Governments of Finland, Sweden, and Freece, and - for the Tunisian program - Mr. Habib Bourguiba, Jr., President of the Association des banques, and Mr. Abdellatif Khemakhem, President of the Institut national de productivité. The program continued in 1975 and during the Bicentennial Festival in 1976.
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We are all very excited here today, as Keith Munt, Co-Owner and Company Director of Saint and Forster Funeral Directors Ltd has been invited to become the new Vice President of the Society of Bereavement Practitioners by the Rev. George Callander, Co-Founder and President. The SBP was set up to celebrate and promote outstanding practice in all fields of bereavement care. George is a close friend of us here at S&F, and offers superb personal service to the families we serve as a funeral celebrant. Over the months that he has worked with us, George has been so impressed with Keith’s attitude towards the profession and the care and attention that he has shown to the bereaved that he has invited him to become Vice President and to help him to deliver training and raise public awareness of the issues surrounding bereavement care. Keith is proud and excited to have been asked to take on this important role and is looking forward to working closely with George in the future to ensure that as many people as possible have access to outstanding bereavement care. MAY
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Cool Name of the Week: Ewan I'll admit it: I have a huge crush on Ewan McGregor. I've seen nearly every movie he's ever been in, from Trainspotting to Star Wars. (He made a dashing young Obi-Wan Kenobi, my daughter and I agree.) And if I had one of those "freebie" lists that many married couples have, he would absolutely secure a top spot—especially if he can look as amazing as he did in Moulin Rouge or Down With Love. And his name would have earned a top spot on my boys' names lists, too. As far as I'm concerned, it's a name deserves to be just as popular as he is. Ewan is a Celtic/Scottish name that means "young." It's a name that might be worth considering if you like some of the more popular boys' names like Owen, Liam, Evan and the like, and are looking for something that's unique—without resorting to spelling Liam Lee-Am. Ewan is pronounced like you-en, if you haven't ever heard it pronounced. And it's a name that hasn't even cracked the top 1000 here in the U.S., though it's a bit more popular in the U.K. Ewan would make a lovely middle name in its own right, but if you did want to use it as a first name, it would pair beautifully with a longer middle name. I'm thinking of names like Jeremy, Zachary or even Theodore. (His parents apparently paired it with a very similar, two-syllable middle name, Gordon.) What do you think of the name Ewan for a boy? Is it a name you would consider for your son? Don't forget: If you're having trouble coming up with great baby names (or just want to run your baby name choice by me), feel free to drop me a line at [email protected]! Photo: Pregnant woman via Ronald Summers/Shutterstock.com
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The transaction, also taking into account bank debt deconsolidation and collection of intercompany receivables, reduces the Enel Groups consolidated net financial debt by over 90 million euros. Rome, November 30th, 2011 Enel SpA (Enel) and CVA SpA (CVA) today executed the agreement signed on October 24th, 2011, regarding the sale of Enels 51% stakes in Deval SpA (Deval) and Vallenergie SpA (Vallenergie) to CVA for a total consideration of around 40 million euros. CVA, a company from the Valle d'Aosta region, already owns the remaining 49% stakes in both companies. The sale received clearance from the Italian Antitrust Authority. Overall, the transaction will reduce the consolidated net financial debt of the Enel Group by over 90 million euros, after taking into account the consideration received for the shares, the deconsolidation of the bank debt of Deval, as well as the collection of intercompany receivables. Deval distributes electricity in the Valle dAosta region with a network of approximately 3,900 km, 130,000 end users and 157 employees, while Vallenergie manages the sale of electricity on the local enhanced protection market, and serves about 107,000 customers with 18 employees (as of December 31st,
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Calling this an inspired piece of photography is probably the biggest understatement. Photographer Jeffrey Martin has captured the largest photograph ever taken of New York City, a dramatic panoramic shot of the city that lets you zoom up close to the windows of buildings like 432 Park Avenue and the Seagram's Building, The Real Deal first reported. If Martin's photo was printed at a standard resolution of 300DPI, the image would measure about 57 feet wide and about 28 feet tall - probably the equivalent of a three story building. The over 20 gigapixel image provides breathtaking views of the city - One World Trade Center, the Brooklyn Bridge, Central Park, and the Chrysler Building just to name a few. For the project, Martin spent four hours over two days atop the Empire State Building with a handheld camera with a 135mm lens. He shot over 2,000 photos to get the final product. And the effort certainly paid off.
https://ny.curbed.com/2016/3/7/11173372/here-now-nycs-largest-photo-ever-taken
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Selection is an important step in the volunteer recruitment process. With a well-planned approach, you'll find the right applicant for your volunteer position. Volunteering has changed significantly over the years. Volunteer coordinators today must clearly understand their roles and responsibilities, as well as the tools available to help them do their job. Managing volunteers, just like managing employees, is not always easy. Sometimes situations can degenerate to the point that the coordinator must intervene. Taking an efficient, disciplined approach will make it easier to resolve these situations. A good volunteer coordinator knows that supervision fosters volunteer satisfaction and improves retention rates. By providing the necessary training, support and followup, the organization equips volunteers to accomplish their tasks more effectively and independently. Screening volunteers is a key step in your recruitment process. You should also screen volunteers whenever they want to take on new duties involving vulnerable clients. Screening ensures an optimal match and enhances the quality and safety of the programs and services your organization offers. Learn more about Do you have a marketing plan? Do you have a good business idea you want to act on? Great! But be careful—you may be so passionate about your idea that you only see the positives. Your enthusiasm may impair your objectivity. So draw up a business plan before you set off on this entrepreneurship adventure. Price influences how customers perceive your products and services and their quality. It also helps determine your company's market share and profits. That's why your pricing strategy is a key part of your marketing plan.
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<issue_start><issue_comment>Title: The ingredients section is missing for new recipes username_0: **Describe the bug** Since the v0.50 update if I create a new recipe the ingredients section is missing **Steps To Reproduce** Please be specific! 1. Click on new recipe from any page 2. No ingredients section **Expected behavior** The ingredients section is missing **Actual Behavior** Unless the ingredients section has moved place I don't see it anymore, I can still add ingredients if I edit through json and then the section shows up again. **Screenshots** https://i.imgur.com/ci18dYZ.png **Device Information (please complete the following information):** - OS: [Debian] - Deployment: [docker-compose] - Browser: [Firefox or chrome] - Version: [v0.50] <issue_comment>username_1: Yep, doesn't show either in edit mode if the recipe doesn't have ingredients. I'll see what I can do. <issue_comment>username_2: Temporary solution is to use the JSON editor, try add at least 1 object in `recipeIngredient` ```json "recipeIngredient": [ { "title": null, "note": "your ingredient here", "unit": null, "food": null, "disableAmount": true, "quantity": 1 } ], ``` <issue_comment>username_3: This is now fixed in v0.5.1 thanks to @username_1 🎉<issue_closed> <issue_comment>username_4: I'm not sure if it is, I still can't see any option for adding ingredients? <issue_comment>username_4: I'm not sure if it is, I still can't see any option to input ingredients on 0.5.1? <issue_comment>username_3: I have it on mine, there's a plus button in edit mode next to the bulk add. <img width="387" alt="Screen Shot 2021-06-17 at 10 56 19 AM" src="https://user-images.githubusercontent.com/64056131/122458665-89c10000-cf5c-11eb-82af-ae731d479507.png"> <issue_comment>username_4: I've got it now, thanks for the fix!
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This is true. Though I would argue in the past and perhaps even now still kids from middle class backgrounds could do well at a public school, go to college, get a good job and move up the ladder at least a little. That drawbridge has now been raised completely and there's nothing we can do about it. I know many people from immigrant families (many undocumented) that went to school in long Beach or other areas and somehow scraped enough money together to attend college and then did well. In fact both my parents came from total poverty- my dad changed elementary schools 13 times because he was raised in a single parent household and they kept getting evicted. They could barely put food on the table. He went to a public high school which is not even ranked nationally. My mother grew up in a bad part of Stockton and her parents were immigrants that worked in the fields picking vegetables. They both went to public schools and were able to go on to college and get decent jobs and lift themselves out (I realize this isn't the norm). My dad's friends were incredulous when he told them he went to college at the 25th year reunion. Stories like that just aren't going to happen anymore. As much as I dislike the typical boomer/gen x mindset of "I did it, so anyone can" at least some people were able to climb out of poverty back then through education. It wasn't common, sure, but it did happen.
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Ah well done hon, I always find that a good run helps to clear the head and calm me down. Such a good way to deal with all the stress you are under, glad you have found an outlet - and what a great side effect that you have lost weight too!
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Facebook is the most popular social media platform and is visited by almost 2 billion people daily. Facebook is like a journal of life, and this huge amount of data allows Facebook to target users in an un-paralleled way. It has become one of the best marketing platforms which is used by all sorts of businesses due to its huge reach and demographic targeting options. Facebook Ads are very effective for travel businesses. Due to its advanced targeting options, Facebook is a a goldmine for reaching and engaging with new customers. Today, more and more people are using Facebook for to research and book their travel; including browsing hotels, resorts, holidays and as such it has become an indispensable tool for travel companies of all sizes. Despite the current popularity of Facebook as a marketing tool, lots of travel businesses are still unaware of it’s potential. So, we decided to write a Facebook Advertising guide for travel companies, to cover all important aspects of Facebook advertising. Travel companies have realised the importance of social media platforms for attracting new business and engaging pre-existing customers. Almost all tour and travel agencies, hotels, resorts, travel agents, and airlines actively use Facebook for marketing in some form. Facebook is one of the most widely used digital advertising platforms and it has several advantages over other online advertising platforms. Facebook allows you to create highly targeted ads which will be shown only to the audience which is more likely to buy your products or services. Another often overlooked advantage of Facebook Ads is the fact through Instagram, a popular image sharing site is owned by Facebook, you can cross promote your ads to Instagram followers also. As is clear from the above list, few other platforms can match the targeting capabilities of Facebook. Facebook offers the option of re-targeting, which is quite like the remarketing ads offered by Google AdWords, as you can target users who have visited your site in the past. Most travel businesses have Facebook pages which can be promoted to potential customers to increase page likes. Liking a brand’s page allows the business to continue to reach out to the follower through targeted ads, as well as on-going exposure to the brands social posts. Facebook Ads uses quite scary targeting to show your page to people it considers likely to be a customer based on their interests or behaviour. Many marketers wrongly assume that showing your ad to millions of viewers will result in increased sales and profits. Several studies have proved beyond doubt that targeted ad campaigns perform much better than generalised ones and this is a mistake which marketers continue to repeat. Targeted ads, on the other hand, tend to have higher CTRs and conversions. Unlike generalised ads, you are reaching people who are my likely to turn into a customer. Facebook allows travel companies to target users throughout the sales funnel. Marketers can easily track the movement of a lead during the sales process and show them relevant ads at each stage. Facebook also remains one of the most effective tools for lead nurturing, as there is a high chance that a user will use Facebook on a continuous basis from the time he first arrives on your site to the moment when he is finally ready to place an order for your travel products/services. Creating targeted ads via Facebook is not difficult. To make things easy for our readers, we’ve decided to show each step for creating a targeted Facebook ad campaign. First, you need to head to the Facebook Ads Manager, which can be found in the left corner of the Facebook News feed under the explore tab. Facebook saved audiences are the audiences which you can define based on people’s interests, behaviour, age, and other metrics such as location. You can create saved audiences in the campaign set up phase or later on in ads manager. As you can see in the above image, Facebook allows you to choose audiences based on their gender, age, languages, and it also gives you the option to exclude specific audiences based on attributes defined by you. With interest-based targeting you can target people who are specifically interested in a subject directly related to the product or service which you are selling. As shown in the above image, interest-based targeting is quite useful for screening out any uninterested viewer as your ads will be shown only to the people who are already interested in your services. Here you will be able to choose people based on their behaviour and you can decide who will see your ad based on several factors such as anniversaries, digital activities, mobile device use, multicultural affinity etc. To fully utilize the targeting capabilities of Facebook Ads platform, you’ll need the Custom audiences which are essentially audiences defined by you. Custom audiences allow you to re-target past visitors of your site or people who have interacted with your content or mobile apps. You can create a custom audience in several ways as Facebook gives you plenty of options to target people whom you want to show ads. You can upload files in CSX or TXT format containing information about your audience such as their phone numbers, email, mobile advertiser id, first name, last name, date of birth etc. Facebook lookalike audiences are quite similar to your existing audience and this feature essentially means that Facebook will use its own algorithm and will create an audience which will be quite similar to your existing audience. You must already have a custom audience before creating a lookalike audience as Facebook uses your data to find lookalike audiences for you. What are Dynamic Facebook Ads? Facebook Dynamic Ads for Travel are a specific format of Facebook advertising which has been specifically created for travel businesses. Dynamic ads allow your travel business to reach users across Facebook, Instagram and Facebook Audience network who are more likely to make a trip. You can use dynamic ads to re-target users who may have started the booking process on your site but abandoned the process in between. Dynamic ads also allow you to upload your travel catalogue along with prices after which specific deals or trips can be shown to your target audience. You will need to implement Facebook Pixel on your site and then upload an inventory of all your trips. Facebook allows you to add location, price, and availability of your trips which are then shown to your targeted audience. Dynamic ads allow you to show ads to people who have shown an interest in your products and you can target them across multiple devices. Dynamic ads are automated, which means that you’ll need to set them up only once and your campaigns are always on. You can also show complimentary offers such as upgrades or any other related service to people who have booked a trip with you in the past. Dynamic ads run on the right time based on your inventory and the actions taken by your potential customers as Facebook uses data collected via the Facebook Pixel and other methods to decide which time is best for showing these ads to a potential customer. Due to several advantages over traditional Facebook campaigns, DTAs have gained popularity among the travel businesses since their launch and several travel businesses including some of the most well-known travel brands have already transitioned to Dynamic Travel Ads. DTAs allow you to increase your ROI as your ads are only shown to an interested audience which allows you to reduce unnecessary ad spend. Travel products are known for the fluctuation in pricing and availability, which used to be a problem earlier as marketers had to update their ads on a regular basis. Dynamic ads allow you to only show up-to-date ads which are based on the data Facebook collects from your website. Facebook’s algorithm automatically decides when to show an ad to a user based on his activity on your website or app and the data feed provided by your website. Bidding is one of the most crucial parts of any online advertising campaign and we will discuss this briefly here. Facebook ad budgets are set at an ad set level and you will need separate budgets for different ad sets. Although, you still need to specify bids per click or impressions for each ad separately. Facebook will divide your lifetime budget evenly across the dates chosen by you for your ad campaign. You can also show the ad delivery optimisation method at this step according to your own needs and objectives. For most marketers Link Clicks is the perfect method for ad delivery although in some cases you may prefer to use Impressions instead of Link Clicks. You also get the option to set the bid manually or leave it up to Facebook by choosing the Automatic option. Facebook will also show a suggested bid which is often in the form of a price range specifying the minimum and maximum bids for an ideal campaign. Facebook and Instagram are both visual mediums and videos and images are among the most prominent content on these 2 sites. Facebook allows you to add videos and images to your Facebook pages and advertisements and you have plenty of options to show an attractive image to a potential customer via Facebook ads. Visual imagery plays an even more important role for travel businesses as people are essentially looking for experiences which are best shown in visual medium. You must also note that imagery is the best form of storytelling as the adage of “A picture is worth a thousand words” still holds true in this era of digital communication. So, choose images and videos for your Facebook ads carefully as the success of your ad campaign will largely depend on them. Facebook Advertising can be your secret weapon if done correctly. Most travel companies nowadays realize the importance of Facebook ads and have started running their own ad campaigns. Due to the nature of the travel industry, dynamic travel ads are better from the point of conversions and sales. Facebook ads are one of the easiest to set up as compared to other advertising platforms and can be efficiently run with minimal investment of time and effort. Travel businesses are a major user of Facebook ads as airlines, hotels, resorts, and travel agents are among the major spenders on Facebook. Just follow the instructions given in this article to set up your own Facebook ad campaign using a targeted and focused approach.
https://apollo.agency/blog/facebook-advertising-for-travel-companies/
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May is starting to become my favorite month out of the year because it’s dedicated to Kindness Awareness in Massachusetts, and every day I hear a new story that makes me smile. This time around, I was on the receiving end of a good deed in Cranston, Rhode Island that put me in a great mood for the rest of the day. There is something so wonderful about people paying it forward when it’s least expected, and rarely do you capture it on camera. I was lucky enough to do both. On Saturday, I decided to treat myself to Starbucks. It’s expensive, but I like to think of it as a special treat. As I desperately cling to my youth, I thought this was the perfect time to film a TikTok in the Starbucks drive-thru. I planned on ordering my coffee and coffee cake in my “radio voice" for the internet's enjoyment, but it turned into something way better. I was elated by the thought of a complete stranger trying to make someone’s day a little better, and they totally succeeded. I paid it forward for the car behind me, in hopes I could make that person smile as widely as I did. I pulled my car over, finished my TikTok, and sat there with the silliest grin on my face. It’s incredible what one small act of kindness can do for your mental state. There is so much negativity in the world, where everyone seems to be self-absorbed and unaware of the people around them. Moments like this remind me that we’re all in this together. Thank you to that wonderful stranger for making my weekend a little brighter and for giving my TikTok a happy ending.
https://fun107.com/cranston-kindness-caught-on-camera/
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How to safeguard your employees from getting sick in the office? As most of the countries are back to their normal lives and business amidst the corona virus that still has no vaccine, we are the ones who should take care of us. We should not only be concerned about us but also other people who are dependent by working for us in the office or being at home as a family member or passing us in any public places. If you are currently running a business during this quarantine, you must visit bulk hand sanitizer canada if you wanted to order the same for all your employees and family members or friends. Employees are the ones who are spending their time to bring us profits in our business. So even though they are paid for their work, you must be concerned about their health during this time as they all will also have lovely family members just like you do. Here are some small things that you can do for them. They are as follows, - If you cannot give a full time salary for the employees during this situation, you can help them find good quality essential goodies to support their life. Just checkout bulk hand sanitizer canadawhich has high quality gloves, masks, sanitizers, gowns and so on that any professional can make use of. You need not visit any real shops which may not be safe to buy all these things. Just order online and get it in your doorsteps.
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Health Communication Message Guide This guide serves as a reference for health communication interventions, by providing a set of core messages that are accurate and consistent. It enable practitioners to communicate standardized messages to communities and audiences. Different guides are available for different health areas including Reproductive, Maternal, Newborn and Child Health (RMNCH); Water, Sanitation and Hygiene (WaSH); Neglected Tropical Diseases (NTD); Malaria and TB. The Federal Ministry of Health and Regional Health Bureaus have endorsed the guides. More Communication for Health Ethiopia resources - The Behavior Change Framework - IPC for Immunization Toolkit - GESI Toolkit - Barrier Analysis Questionnaires - The Infection Control Symbol Package - Advocating for Social Marketing Programs to Local Stakeholders - Moving the Needle on Health Behaviors - Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents - WASH FIT / WASH FIT Mobile - La Planification Familiale dans les Situations d'Urgence: Essentielle,, Voulue, Necessaire et Realisable
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Difference between revisions of "Males s Full Lacrosse Sticks" Latest revision as of 11:26, 10 November 2019 Lacrosse is a sport performed by two opposing groups with a rubber ball and a protracted stick generally known as crosse. If you first purchase a stick - particularly a boys stick - it won't be "broken in" but, that's, it isn't prepared for play. All pockets have to be broken in to some extent, however some are far easier than others. Working towards these drills day by day will assist to enhance your stick dealing with, ground balls, and passing capability. It is a women's lacrosse stick that is aimed very a lot at beginners. Everything from the broad head and stiff sidewall bars will help with retention and choose up, whereas the top also falls simply shy of offset maximum, which can further support with retention whilst you discover your toes as a greenhorn. It's possible you'll hit the candy spot each time with this lacrosse stick designed only for women. The STX Crux 500 claims to have 10-diploma know-how that helps drive the ball into scoring range. This stick also has a fast release and materials that bonds with the ball for better-endurance. With its design, this stick teaches your kid how you can use a full-sized shaft. It contains a huge head to extend the probabilities of catching the ball. The elevated catching space lets the kids have enjoyable from starting to the tip. You may be on cloud nine after you make investments some severe money on a stunning lacrosse stick and string it up so it throws easily. As a result of box lacrosse has a 30 second shot clock. The quantity of pictures per game is far larger than that of out of doors lacrosse. The sport is forwards and backwards which gives gamers many extra possibilities and touches than they might have otherwise. For instance, a penalty in field lacrosse is 2 minutes long compared to 30 seconds for outside! Meaning you might be assured 4 possessions on man up (30 second shot clock). Tripping: Happens when a player obstructs his opponent at or below the waist with the stick, arms, arms, ft or legs. STX lacrosse sticks feature properly-designed heads. This stick is sturdy, comes full with every thing you should play, and makes it simpler than ever to be taught new expertise out on the field. Some of the essential parts of lacrosse is with the ability to go the ball successfully. Even the most effective lacrosse gamers on this planet continue to observe their passing abilities, as a result of passing is essential to turning into an important lacrosse participant. To start with, if you're in search of something aesthetically pleasing, this stick won't disappoint. The stick is out there for buy in purple and white, white and black, or black and gray, which makes it look just as great because it feels. In your arms, the stick is lightweight and easy to manage. The head of the stick includes a medium mesh that's not fairly arduous and but not fairly soft. However, the string softens up for great gameplay reasonably quickly. The fact that you may break-within the pocket so quickly means you can get out onto the field and start dominating in no time. Apply your ground balls. Know that video games are received and lost on floor balls. While approaching the ball, step to it using the proper foot: in case your stick is in your right hand, place your right foot near the ball, and vice versa. Sink your hips and put the head of your stick parallel to the ground. The butt of your stick ought to get down low as effectively. Scoop by way of and produce the top to your face. Immediately look for the outlet to a teammate. This is without doubt one of the best full lacrosse sticks for girls. You'll know it's designed for ladies based mostly on the colourful green coloration with a mesh design on the shaft. Its sidewall design reduces its weight considerably whereas nonetheless making certain that that the unit is powerful enough. This makes it helpful in numerous conditions and completely different parts of a lacrosse pitch. Source: How to play lacrosse for beginners The surplus piece of high string can be used as a bottom string. Again, tie a knot at one end earlier than you begin. There are a lot of alternative ways to tie the underside of a lacrosse stick based mostly on your private desire, however follow the identical common methodology as high strings and sidewall strings. Backside strings can be later adjusted for elevated pocket depth. MOMENTUM is a key ingredient of LACROSSE BLAST, and much of the sport hinges on it. When a staff has MOMENTUM, it will get a lift in both taking pictures and play-making potential. MOMENTUM may be gained shortly by big hits, spectacular saves, sudden objectives, or fights. However, it can be just as quickly LOST, with errors, momentum-killing events or penalties. It is utterly defined in the guidelines, but for our demonstration functions we'll just point out the distinction between the solid stars within the players' SHOT and ASST scores, and the "outlined" or "white" stars. Spencer Gallard, for example, has two ASST stars-one strong, one outlined. Having momentum allows Gallard-or anybody on his staff-to use EACH strong AND outlined stars on assists and pictures.
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Hello crafty friends! My name is Jung AhSang, and I am so excited to be back for another guest post on the Spellbinders blog. I love to make handmade cards, I’m a scrapbooker, and I like to do crafts with my 3 girls. If you’d like to follow my crafty projects, my blog is jungahsang.wordpress.com. Today, I’m working with the new Christmas Foiled Basics collection by Yana Smakula. When I looked at all the pieces in this set, I realized that I could make some great foiled backgrounds, and include a simple, but elegant sentiment. For my first card, I created a classic red card using the Christmas foliage background. Using my Glimmer Hot Foil system, I foiled the Christmas foliage background using blush foil and red cardstock. I used the plate and foiled it twice to create a full background. To make sure I lined up the foiling on my card, I used washi tape to tape the foil and glimmer plate into position. There are a few videos on the Spellbinders YouTube channel demonstrating foiling tips; one of the videos is called “Top 10 Glimmer Hot Foil Tips,” which you might find helpful. On another piece of red cardstock, I foiled the “Happy Holidays” sentiment plate and a dotted circle plate. I die cut the sentiment using one of my circle dies. To assemble the card, I trimmed the background panel slightly, and adhered it to a white A2 sized card base using foam tape. Next, I used some gold thread from my sewing stash for a little texture, and adhered the circle sentiment with foam tape right on top. For my next card, I created a rich green card using the Glimmer gift border plate. I created my second card very similarly to the red card. I used sliver foil, and foiled the glimmer gift plate twice to create a full background. I used the “Merry & Bright” sentiment, and decided to turn my sentiment circle into a tag, especially since my background is filled with gifts. I punched a hole in the circle sentiment, and added a red floss bow. I wanted to make one more background card for my collection of holiday cards. For my third card, I used some of the foliage plates from The Christmas Organic Foliage set. I used 5 of the foliage plates over and over, exactly as I would use stamps to create a background, and puzzle-pieced a full background. To keep all the plates from shifting while I was foiling, I used washi tape. I used gray cardstock, silver foil, and the “Joy To The World” sentiment. To add some interest to this card, I used some crystal drops. Cardstock, gold thread, Red floss, Nuvo crystal crops in the colors calming aqua and blue babe, foam tape. I am thrilled with how my cards turned out, and I’m so happy to have some Christmas cards made! I love the elegant touch that Yana’s Christmas Foil Basics adds to handmade cards, and I love the double font on her sentiments. Thank you so much for stopping by, and have a lovely day!
https://spellbindersblog.com/2020/09/15/trio-of-foiled-background-christmas-cards-with-jung-ahsang/
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Sarsfields, who won five of their six county titles between 1989 and 1997 – becoming the first side to win successive All-Ireland titles along the way – have been working on underage in recent years and the current crop contains the next generation of many of those who triumphed in the 1990s. But they were ousted by a Mellows side for whom county player David Collins manned defence and aside from Callanan’s exploits, Brian Lee, younger brother of Galway defender John, hit three great points from play. Sarsfields, with wing-back Darren Skehill rock solid, led by 0-9 to 0-4 having played with the wind in the opening half, with Kerrill Wade hitting five frees. But they managed just two in the entire second half with Callanan drawing Mellows level with 11 minutes left and sub John Hughes sealed the win with a brace of points in addition to another from Callanan after Joseph Cooney – son of Galway legend Joe – who blasted one over the bar for Sarsfields. Former Galway player Mark Kerins was the key figure as Clarinbridge saw off the disappointing challenge of St Thomas 2-15 to 1-8 to reach the quarter-finals of the Galway SHC at Athenry yesterday. Kerins hit 0-9, seven of them from frees, most of which he won himself, and brother Alan also shot 0-3 from play. Both sides were reduced to 14 men with referee Alan Kelly adopting a hardline policy on discipline and he dismissed Clarinbridge’s Jamie Cannon and John Conroy of St Thomas for their part in a brawl after 11 minutes. Both sides concentrated on hurling after that with Clarinbridge recovering from a Bernard Burke goal as Alan Kerins set up Paul Coen for a goal which helped them lead by 1-5 to 1-4 at the break, having played against the wind. Three points without reply inside six minutes pushed Clarinbridge further ahead as Mark Kerins continued to dictate and the game was over as a contest when Eoin Forde blasted home after a superb crossfield ball from Stephen Forde. Elsewhere seven unanswered second-half points from Tynagh/Abbey/Duniry secured them a place in the quarter-final with a facile 0-12 to 0-8 win over Castlegar in Athenry. Castlegar led by 0-7 to 0-5 at the break thanks largely to a 65, a sideline cut and a free from Ger Farragher. Castlegar, the most prolific winners of the Galway SHC title with 17 crowns but who have not won it now since 1984, looked likely to win when Ronan O’Flynn pointed five minutes after the restart to increase the lead to three. However, three scores each from Padraig Brehony and Shane Moloney and a superb effort from substitute and former All-Star Kevin Broderick ensured Tynagh/Abbey/Duniry a place in the last eight. The victors – who had Ger Burke sent off late on for a second yellow – were never troubled after the restart, but three missed frees from Farragher did not help Castlegar’s cause. A strong final quarter sealed Craughwell’s place in the quarter-finals when they proved too strong for Kinvara at Loughrea, winning 0-11 to 0-8 on Saturday. The scoring power of Craughwell was too much for Kinvara who looked to have the match of their opponents early in the second half. Kinvara started briskly when playing into the breeze and Shane Quinn and Conor Kavanagh struck over a brace of points but Michael Coughlan, Keelan Cullinane, Niall Healy and Jamie Ryan responded for Craughwell. Craughwell led 0-7 to 0-4 at the break as Kinvara had a mountain to climb with the decision by Kinvara to play county team full back and captain Shane Kavanagh at centre forward clearly not working, as Fergal Healy marshalled the Craughwell defence. Successive points from David Huban and another from Shane Quinn brought Kinvara back level at the start of the second half, but Craughwell’s defence again put up the barriers and Keelan Greene, and three Niall Healy points, sealed Craughwell’s win.
https://www.irishexaminer.com/sport/gaa/arid-20131263.html
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A girl of two used FaceTime to save her heavily pregnant mother when she collapsed at home. Katie-Marie Porter, 27, suffered a suspected anaemic blackout while she was looking after her daughter Myah. The family said the toddler knew how to use the video calling app from watching her mother use it. Myah’s father Kirk Powell, who was out shopping during the drama last week, was alerted by Myah’s grandmother and rushed back to the family home in Newport, South Wales. Charles Manson's grandson reveals he will cremate his body... Boy, 14, suffers 'life-changing' injuries after being shot...
https://www.dailymail.co.uk/news/article-5501895/Girl-two-used-FaceTime-pregnant-mother-collapses-home.html
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<issue_start><issue_comment>Title: Authentication username_0: How are authentication tokens to be passed around (@username_2 and @username_1 ) <issue_comment>username_1: @username_2 and @username_0 I've put together some notes on compatibility between Globus Auth and the DataONE Identity services to kick start this discussion. **Token Format.** [Globus Auth](https://docs.globus.org/api/auth/reference/) supports using JWT Bearer tokens on REST calls, as does [DataONE authentication](https://purl.dataone.org/architecture-dev/design/Authentication.html#using-access-tokens). The definition of the Globus JWT tokens follows the OpenID Connect specification (https://openid.net/specs/openid-connect-core-1_0.html#IDToken). DataONE follows [RFC 7519](https://tools.ietf.org/html/rfc7519#section-4.1), and therefore uses an extremely similar set of fields, including `sub`, `iat`, and `exp`. OpenID Connect seems to "require" a couple more fields, including `iss`, `aud` -- these could probably be added to the DataONE auth tokens easily. Once a token has been generated, it is passed to REST services using the standard HTTP header, e.g., `Authorization: Bearer <token_value>`. **Token Signing.** The bigger issue is probably the trust network. Currently, the DataONE Authentication service signs its JWT tokens using an X.509 certificate that is trusted by all members of the DataONE network. It delegates authentication requests to identity providers that it trusts, namely [ORCID](http://orcid.org) and [CILogon](http://www.cilogon.org). I'm not sure who the signing authority is for the Globus Auth tokens, but overall the infrastructure seems highly compatible, and could be completely compatible with a few surgical changes. **Representing Subjects.** DataONE uses the subjects returned from ORCID and CILogon directly within strings to represent the principals in various places, including in [metadata describing object ownership and access control rules](https://arcticdata.io/metacat/d1/mn/v2/meta/doi:10.18739/A24H1Z) that are used for authorization decisions. DataONE has decided to represent ORCID values in their URI format (e.g., `http://orcid.org/0000-0003-0077-4738`), and Distinguished Names (DN) from CILogon are always serialized following [RFC 4514](http://tools.ietf.org/html/rfc4514) (e.g., `CN=<NAME> B36802,O=University of California-Santa Barbara,C=US,DC=cilogon,DC=org`). I am unclear how these serializations relate to how Globus Auth represents subjects. The CILogon DNs are problematic because they add a numeric qualifier onto the cn attribute, and this is not always reliable for all identity providers. This is an edge case problem, but can cause issues in practice. Within DataONE, we also use and define three [_symbolic principals_](https://purl.dataone.org/architecture-dev/design/Authentication.html#identity-management-service) that can be used to represent classes of users in access control rules, including the `public` user for unauthenticated access, the `authenticatedUser`, and the `verifiedUser`. **Groups.** DataONE maintains a list of groups, and users can create their own groups via the DataONE API using the createGroup() and similar REST methods (which is also exposed via each user's profile page on the web). Each group has a DN that can be used anywhere that a user identity can be used. **Identity mapping.** DataONE has services that allow two identities to be mapped as equivalent. Within DataONE, this requires first authenticating as one identity, then requesting a mapping to a second identity, then authenticating as the second identity, and confirming the mapping. Once confirmed, the two identities are considered equivalent, and all rights of one identity are accessible to the other. This is used extensively to map historical user identities to our preferred approach of using ORCID identities. Globus Auth seems to have a similar service, and so we would need to share these identity equivalence mappings for authorization to work seamlessly across systems. This will require discussion. **DataONE Identity Management service.** See [identity service docs](https://purl.dataone.org/architecture-dev/design/Authentication.html#identity-management-service). So, where do we go from here? <issue_comment>username_2: @username_1 This is a really great write up. I think you're right that the two approaches are very much aligned. Here are a few more notes from the Globus Auth perspective. Token Format. Globus Auth follows the OpenID Connect specification. The results of authentication are a collection of scoped access tokens (for each resource server requested). Individual access tokens are passed using a standard HTTP Auth bearer header. Token signing: Globus Auth tokens are signed by a key held by Globus. That key is trusted by all Globus services. Representing subjects: Globus Auth identifies principals using different formats depending on the IDP. For example, CILogon ePPN (identity name) and ePTID ("provider specific id" that's guaranteed to never be reused) are treated as the unique identity. All Globus AUth identities are uniquely identified, include unique subject identifiers from the IDP and an asserted text username of the form <name>@IDP. Groups: Globus runs a separate Groups service that provides self-management of arbitrary groups. The Groups service lets users create groups, invite other users to the group, management memberships, implement invitation and approval workflows, and set other policies (e.g., viability, membership information requirements). All groups are uniquely identified by UUIDs and can be used for authorization. Identity mapping: Globus supports a similar identity linking model, in which any number of identities can be linked together via authentication with each. These identities can then be presented as a set after authenticating with any one of the set. OAuth workflow: Globus supports a typical authorization code grant in which users are redirected from a third-party application to Globus Auth (and on to registered IDPs). This flow also supports PKCE forunauthenticated clients (e.g., CLI/tools). It supports an implicit grant workflow that can be used by client-side javascript applications that cannot provide client authentication. It also supports a resource owner password credentials grant flow which allows client applications (e.g., CLI/Tools) to be used by users without needing to follow a web-based workflow. <issue_comment>username_1: @username_2 Thanks. Can you add an example of a subject representation in a text string as it might be used in an access rule or other policy framework? <issue_comment>username_2: When using identities in access rules we use a unique UUID that is assigned to the identity. The reason is that the usernames asserted by an IDP are sometimes reused and are therefore only guaranteed to be unique at any point in time.
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Ajax Amsterdam midfielder Donny Van Der Beek has all but confirmed the Real Madrid’s interest in him. In a chat with Fox Sports, the 22-year-old Dutch international midfielder revealed that there’s interest in him. Donny Van Der Beek has been linked with a €60m move to Spanish La Liga giants Real Madrid in recent days. The Arsenal target is seen by many as the Plan B option for Real Madrid in the event that the Los Merengues don’t sign Manchester United midfielder Paul Pogba. French international Pogba is the top transfer target for Real Madrid but his €180m transfer fee is a big stumbling block in addition to the fact that Manchester United are reluctant to do a deal for him. Arsenal target Donny Van Der Beek has enjoyed a rapid rise in the last year after he played a big role for Ajax Amsterdam in the last campaign. Ajax Amsterdam won two major trophies namely the Dutch Cup title and the Dutch Eredivisie title. The 22-year-old was also a key player for Ajax as they reached the semifinals of the Champions League before they were eliminated by Tottenham Hotspur in heartbreaking fashion following the last gasp strike from Lucas Moura.
https://www.thewistle.com/2019/08/03/arsenal-target-confirmed-real-madrids-interest/
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I mean, I see the logic, and the numbers are closer than I thought as long as we forgive Scutaro for getting hurt and we just look at his rate stats. I'm not sure that's really fair though. If we could just take the first half of Bogaert's 2016 then it would be him and it wouldn't even be close - in fact, he'd challenge Nomar for the starting spot. But we can't do that because a huge part of the game is putting together full, healthy years. Bogaerts slumped badly down the stretch of 2016 and Scutaro got hurt. Overall, Bogaerts was a win better according to BRef and 2 wins better according to Fangraphs. As for the position thing, I guess it's just two different ways of playing this game. I tend to think that any real life GM would take Bogaerts and trust that, as a SS, he could slide over to 2B and be fine. But I can also see the fun in trying to choose actual utility guys to full the utility spots on these "dream teams."
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Note: Uploading of people attribute data into SWOOP does not change anything Yammer/Workplace. If none of these methods are used SWOOP will use Yammer/Workplace's Department field. Download the list of users in Yammer/Workplace. If you include the userID in the user.csv file then you now can delete the email field if you don't want to share the email addresses with SWOOP. Go to the SWOOP miner: You access the miner by clicking on 'Admin' in the footer of SWOOP, then click on the tab called 'Miner', then click on the URL for the data miner.
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# boot.py -- run on boot-up # can run arbitrary Python, but best to keep it minimal import machine import pyb pyb.main('simp.py') # main script to run after this one #pyb.usb_mode('CDC+MSC') # act as a serial and a storage device #pyb.usb_mode('CDC+HID') # act as a serial device and a mouse
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No matter the situation, Bailey finds the fun in it and so has been nicknamed Bouncy Bailey! She enjoys running after toys, pouncing on them and then shaking her head all while jumping in the air. Soft toys are her favorite and she’s happy to entertain herself by chewing on them in between the pounces! You can also see her bouncing across the play yard, chasing or being chased, with another dog. Bailey’s most endearing trait is stopping everything to get some pets from her favorite humans. Just a young girl, Bailey has lots of happy years to give to a family.
https://www.bchumane.org/video-bouncy-bailey/
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Not surprising there was no economic moat. Lots of other companies copied tom's design and sold it for half the cost.
https://businessinsider.ltworlds.info/the-rise-and-fall-of-toms/zJSJzZZldc5moqQ
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": The 21 Irrefutable Laws of Leadership by John Maxwell Get the book Meeting frequency: We will attempt to meet every other month in 2021, Starting in February.Book list: We plan to have an ongoing list so you can prepare ahead of time, or procrastinate indefinitely 😊. Below are upcoming reads after this meeting. At each meeting, we’ll add one new book so you can always see the next couple reads. Books for 2021Apr 7, 2021: Genghis Khan and the Making of the Modern World – Jack Weatherford - RSVP HEREJun 2, 2021: Lights Out: Pride, Delusion, and the Fall of General Electric by Ted Mann and Thomas Gryta - RSVP HERE Wednesday, February 3, 2021 5:00 PM - 6:00 PMCentral Time CFA Society Minnesota
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More than 1000 companies and investors, including the Chief Executive Officers of Fortune 500 companies, last Saturday, joined the campaign on carbon pricing. The collaboration was coming about two weeks after the campaign was flagged off at the UN Climate Summit in New York, USA, which announced the results of months-long campaign to put a price on carbon. But after last Saturday’s meeting with the World Bank Group and key stakeholders, Jim Yong Kim the president of World Bank disclosed that more than 1,000 companies and investors, and 74 governments have so far joined the pledge to put a price on carbon. According to him, the Washington meeting brought key members of the group including leading global investors, Fortune 500 CEOs and government officials from across the world together to talk about next steps to realise the dream. He disclosed, however, that some investors are already “decarbonising” their portfolios and moving toward green investments because they may become more competitive. With respect to global action on Ebola at the annual meetings, he said the understanding was that key institutions and countries had committed themselves to communicate the urgency of the situation. He stated that the UN Secretary General, Ban Ki-moon, had told countries not to wait for consultation but to take action immediately, stressing that even the IMF Managing Director, Christine Lagarde, had urged affected countries not to worry about fiscal deficits in the midst of the crisis as measures are being taken to accommodate such lapses. Kim said the overall message was for all stakeholders to pick up the pace and do whatever it takes to stop the Ebola outbreak. The World Bank boss noted that while efforts are being made to combat Ebola, it has become imperative to provide contingency arrangements to counter the next contagion, hence it’s extensive consultations over the past few weeks with leaders of the G20, the UN and the IMF, about the pandemic emergency facility, such that when the next global health emergency hits, a set of pre-packaged agreements would ensure that funds were immediately available and flowed freely to support response efforts.
https://www.magnartis.com/fortune-500-ceos-investors-partner-world-bank-on-carbon-pricing/
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Built for Gaming: A fantasy RPG setting needs a reason for wandering heroes to travel into the wilderness, fight monsters, and take their treasure. Thus towns and castles must exert control only over a local area, with outlying regions infested by robbers and monsters. Empires must have collapsed and lands grown depopulated in order to provide a source of ancient ruins and treasure, and an ancient war or wild magic must have created terrible monsters that, in the declining age, can no longer easily be held in check. The Auran Empire setting was defined with these needs in mind. Genre: The setting is adventure fantasy, not high fantasy. Adventurers seek fame, power, and loot. Nobles live in luxury while slaves toil in misery. Human cities teem with vice and villainy. Virgins are sacrificed to chthonic cults. The characters may be adventurers like Conan, or willing heroes like Aragorn, but they are not reluctant heroes like Frodo. Era: The era is historically akin to the age of Late Antiquity circa 350AD as the Roman Empire slipped into the Dark Ages. Opulent long-standing empires are shattering in a tidal wave of violence. It is not the Middle Ages and the tropes of the Middle Ages (knights in shining armor, chivalric orders, and so on) are not strongly present. Cultural Analogues: The Auran Imperial culture is based on Late Rome/Byzantine Empire. The Sunset Kingdoms of the west are akin to Indo-Persian civilization. The North is akin to German (Anglo Saxon) civilization. The Skysos riders of the far west are based on the Asiatic mounted hordes (Huns) that threatened the Late Roman Empire. Northern Elven culture is Celtic British, assuming it had not been Romanized. The deceased classical elven civilization is “Atlantean” (hypothetical Bronze Age with both Greek and Egyptian motifs combined with early Christian burial practices). The deceased Thrassian (Lizard-man) civilization is inspired by Aztec civilization with an Assyrian aesthetic, while the deceased Zaharan civilization is inspired by Babylonian, Egyptian, and pre-Hellenistic Persian civilization. The early Auran Empyrean era civilization is Heroic Age Greco-Roman (Illiad, Aeneid). This creates a wide range of settings, ruins, and landscapes for adventure. Pagan Religion: The gods did not create the world, nor are they omnipotent or omniscient; and they fight each other to control the world, not to redeem it. As such, religion is a powerful force, but does not dominate Imperial society. Ammonar’s worship is akin to the worship of Sol Invictus in the Late Empire, or the Byzantine Christian Church (i.e. subordinate to the Emperor, rather than vice versa). The other Empyrean gods are mystery cults popular with different factions of society, much like Mithra, Isis, etc. The Chthonic gods are worshipped by various city-states in the Sunset Kingdoms, much like occurred in the ancient era, and there priest-kings are common. Alignment: The setting assumes a perpetual struggle between Law and Chaos, but not in a sense of “good” and “evil”. Law represents humanity and its works; Chaos represents inhumanity and its alien works. To have an alignment is to have chosen a side in this perpetual struggle. Most people, choosing no side, are Neutral, although most Neutral humans enjoy the protection of Law. (To paraphrase George Orwell, Neutral humans sleep peaceably in their beds at night only because Lawful heroes stand ready to do violence on their behalf.) Human vices, such as greed, lust, and vanity, are widespread and common; the true enemies are characterized by inhuman vices, insanity, wanton destruction, cannibalism, necrophilia, and so on. Evil is all-too-human, but chaotic is something both less and more than human. Heroic Morality, Not Modern Morality: “With great valor comes great reward.” Like Achilles and Beowulf, and unlike Spider-Man, heroes seek out fame and fortune. A beautiful wife, chests of gold, magnificent weapons, and grants of land are considered by all to be the rightful rewards for great deeds of valor on behalf of Law. Wealth is a positive value, a symbolic measure of a man’s worth. When the Planes are Right: The Material Plane, a great crystal sphere made up of all the elements, floats within the center of an infinite silvery sea known as the Astral Plane. Above the Material Plane is the Empyrean Heaven, source of law and goodness. Beneath the Material Plane is the Chthonic Darkness, the source of chaos and evil. Ringing the Material Plane are the four Elemental Planes of Earth, Air, Water, and Fire. These positions are not static, for the 4 Elemental Planes and 2 Outer Planes metaphysically orbit around the Material Plane, interacting with it and each other. Depending on their current location, the Planes are considered in one of four states: Ascendant (close to the Material Plane), Descendant (far from the Material Plane), Conjunction (actually touching the Material Plane), and Eclipse (furthest from the Material Plane). The planes were set adrift from their natural orbits when the Tablet of Destiny was shattered, and their movement is now partly dictated by spiritual factors as well as physical law. The shifting of the Outer Planes, which is part of the struggle between Law and Chaos, is greatly correlated with, but not causal of, great historic events. One such great event, the Awakening, looms as a possibility in the future. There Is No Destiny: The Tablet of Destiny was shattered in a primordial age. Fate is adrift, and the outcomes depend on the will of men and the whims of chance. Gods and heroes can seek to influence the outcome but there is no assurance of a happy ending. In game terms, PCs can and do die, the Awakening may or may not come to pass. Magic is Natural but Mysterious: The setting’s level of magic is equivalent to what the ancients historically believed magic to be capable of; which is roughly the implicit level of magic in B/X Dungeons & Dragons, not the high level of magic assumed in 3rd Edition or 4th Edition Dungeons & Dragons. It is wrong to treat magic in a scientific manner, because the entire society is pre-scientific. It is equally wrong to treat magic as fundamentally non-comprehensible, either. Instead, magic is considered part of “natural philosophy,” which is the pre-scientific manner that classical thinkers attempted to understand the world. Physics and metaphysics are not yet distinguished; an alchemist is both a scientist and sorcerer. Weird Science: Ancient civilizations from long-forgotten eras had advanced in scientific knowledge beyond what is known to the setting. Ray-guns, death rays, floating packs, grenades, and laser-swords can be found in rare and out of the way places. The ruins of the elves and Zaharans are comparatively recent (circa 3000 years old) compared to these far more ancient artifacts. Monsters were Mostly Created: While some creatures, such as dragons and unicorns, are natural to the world, most monsters, including giant vermin, undead, all aberrations, and all evil and monstrous humanoids, were created, either when the Tablet of Destiny was shattered, or by the elves, Thrassians, and Zaharans as slaves, pets, and soldiers. As such they are innately unnatural and should be destroyed. PCs need have no moral qualms about killing orcs, undead, and so on. Literary Inspirations: Key inspirations for the setting are R. E. Howard’s Conan stories; Lin Carter’s Thongor of Lemuria series; Michael Moorcock’s Elric of Melnibone and Hawkmoon series; David Gemmell’s Drenai series; R. Scott Bakker’s Prince of Nothing series; and George R.R. Martin’s Song of Ice and Fire series. Hopefully you find this setting as exciting and appealing as we do! But, of course, if you hate it, it's easy enough to ignore. There's nothing to prevent you from using ACKS with your own favorite setting, Rob Conley's Wilderlands of High Fantasy, Gygax's Greyhawk, Arneson's Blackmoor, or anything else! I have to admit that I was a little worried when the Middle Ages were dismissed as an inspiration, but the assumptions of this Auran Empire setting are very close to those of my own campaign. For example, the way the B/X alignment has been subtly reinterpreted as supernatural allegiance (or the lack thereof) is exactly the way I've been doing it since I started looking at classic D&D. I'm surprised and excited to see a soon-to-be-published game that has all the tropes I enjoy built-in. I agree. What a long history this setting has. It nails that apocalyptic vibe that Tavis wrote about last year. Also, all those layers of civilisation allow for treasures that are culturally significant. Rather than criticisize, I'll just say settings are a matter of taste, but that brings up the question of why have an official one? I'm no expert on the gaming market these days and buyers expectations, but I wonder, do you feel required to make a setting to go with the game for sales purposes? It is, after all, a lot of work to create a setting top down and many (most?) gamers will ignore it for one of thier own or for an Arnesonian bottom up approach. 1) Whether you include a setting or not, there's an implicit setting that exists because of the rules. This is especially so in ACKS, since the economics have a lot of assumptions built-in. We think it makes sense to be explicit about what's implicit. 2) Most people enjoy the flavor text associated with a setting, even if they don't use the setting. Eye of Vecna is cool even if you don't use Greyhawk. 3) We have a setting already written - the setting predates the game. Loving this aspect of ACKs even more than the already great ideas of domain rule and Napoleonic mass combat, and non-Vancian (more maybe Vancian-influenced) magic system. Getting more and more excited to receive my print copy. Great job ya'all. I'm not crazy about the alignment system. When the legal system can cut off your hand, brand you, hang you, or crucify you, connecting Law/Chaos implicitly with Good/Evil (sorry, but it is considering the scary atrocities associated with Chaos and the "protection from evil" spell) seems weird. Another thing, necromancy is so connected to chaos that only chaotic mages can perform it, but creating monsters by combining creatures against their will has no such issue seems odd. Yeah, gods can be fickle that way.
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In order to be more responsive to the needs of its affiliated sisterhoods, Women’s League is divided into 13 regions (formerly known as Branches). Regions are divided into local areas to encourage camaraderie and participation. Each region has its own board of directors and provides services, conferences and Consulting Services. The region presidents are your personal links to Women’s League sisterhoods, events and programs in your area of the United States and Canada. The following are the Women’s League regions with the states and/or provinces that are represented in each. Click on the region name to see a list of all the sisterhoods within that region. You also can link to the region website as well as contact the region president directly.
https://www.wlcj.org/about/regions/
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A few weeks ago, my wife and I went out for dinner. Good food, good wine. A really nice, relaxing time. We ran into friends on the way home. My buddy, another near-obsessive basketball fan, asked me if I saw Bargnani’s line. Huh? There was no game tonig… I froze. It happened. Did I misread the schedule? No. It seems that while my relationship to the NBA has never been stronger, my Raptors Fan Ranking has gone from “sorry-officer-I-was-speeding-because-I-forgot-to-factor-in-potential-overtime-when-I-set-the-PVR” to actually forgetting about a game entirely. How did it come to this? There are marriage counselors, family counselors, career counselors, but since sports counselors don’t exist, I’ve had to take a cold, hard look at my 15 years of Raptor fandom. In doing so, one thing became clear: the circumstances leading to this crisis (and I use the term loosely) are directly tied to my age (29) and my location (Toronto). In other words, being a Raptors fan born in the early-mid 1980’s is unique, complex, and at times, difficult. In the process of this analysis, a parallel became evident between my trajectory from pubescent screaming superfan to balding, coughing Raptor skeptic – the framework of a typical NBA game: First Quarter: Tip off. The game begins. The Raptors: Pinstripes! Dinosaurs! Mighty Mouse! Isaiah! Professional basketball in Canada is here! The sky’s the limit. No one cares if they lose, we just love that they’re here. Oh, and Zan Tabak! The Dinosty: Already a huge basketball fan thanks to Jordan, Penny, and Shaq, I couldn’t sleep the night before the first Raptors game. New toys are always so shiny! Their inaugural season coincided with the first year I was allowed to take the subway downtown with a friend. Watching my NBA heroes play in my city, AGAINST my city, took me from the couch to the court and offered entry into the “true fans” club. The team and I shared a tandem evolution. Second Quarter: Teams are establishing their rhythm and flow. Starting to get a sense of who’s bringing what to the table. The Raptors: A high-octane, high-flying highlight reel named Vince Carter was quickly becoming the most exciting player in the league. And in Toronto! We’ve never had the most exciting anything in, well, anything. Vince was complemented by an entertaining and talented entourage: T-Mac, AD, MoPete, Boogie, JYD, Onions, Goomba, HotDick… (the last two were to see if you’re still paying attention. Obviously, HotDick played for the Mavs.) Everything was looking up – The city of Toronto was riding the rush of the Raptors. The Dinosty: Best described as 12 minutes of pot and heavy petting. The Leafs sucked, the Blue Jays played baseball, and no self-respecting teen gave two shits about the Argos. The Raptors had a monopoly on sports buzz, and it was easy to keep track through a haze of smoke and general indifference. Add basketball video games to the mix and I had a bad case of Purple Fever. Halftime: A break to regroup with a plan for the second half. The Raptors: Full-on Vinsanity. Sellout crowds experienced three consecutive playoff trips, including a last-second loss in the Eastern Conference Semi’s. The Dinosty: It was during this time that my family moved to Arizona. In true teen form, I was bitter. I rejected everything American for its familiar (though often inferior) Canadian counterpart. That the Raptors had become one of the darlings of the league – #15 jerseys were EVERYWHERE in the states – helped keep me interested in their progressions, when it would have been easier to adapt the local Suns as my squad of choice. Third Quarter: Teams implement their new plan. Sometimes it works, and sometimes…you get blown out. The Raptors: Vince leaves, forcing management to Frankenstein a marketing plan and usher in “The Bosh Era”. Plus, a season of Kevin O’Neill, who later went on to a sterling career as the Travelocity Gnome. The Dinosty: University years. Occasionally, drinking and sports got in the way of attempted intercourse and drug experimentation. The Raptors and the Dinosty both slip into a dark period. Luckily, we both graduated and moved on to bigger and better. Fourth Quarter: Time is running out. You pull out all the stops in hopes of a win. The Raptors: Chris Bosh’s emergence as a premiere big-man (deleted, “Franchise Player”) helped right the ship and led an entertaining run, including a return to the playoffs. A volley of missteps and tangential strategies (EuroRaptors, JO, Kapono) aimed at keeping CB4 happy led to some serious PR tightrope walking from our head office, and some serious vitriol from fans. The Dinosty: Got a job, got a house, got married, got bills. Went from being a fan to being a consumer. The longest 3pt. streak in NBA history stopped being enough. I became disappointed as they continued to offer up a declining product year in and year out, wrapping their efforts in transparent spin – all while increasing ticket prices significantly and cramping two new seats into many ACC rows. Increased price + decreased product = re-evaluation. At the buzzer: Ice your knees, lick your wounds, and review your performance. The Raptors: Bosh leaves, yielding nothing in return. The team searches for answers, essentially back to square 1. Could the current team beat the expansion-season roster? Who cares, as they become a non-factor in the NBA, especially within the context of a pivotal season in the league’s history. The Dinosty: Disenfranchised with the team, the front office, and the lack of relatable personalities, I stop defending them in conversation with casual, uninformed fans. I didn’t care enough. It’s easy to develop a man-crush watching guys your age do things you could never dream of. On this Raptors team, who can I rally behind? I must admit, I do like Reggie. It’s something, but it’s not enough. And what is “sport” if not a fantastical outlet? The youth movement is considerably less appealing when you’re not caught up in the hype. My buddy Jon made a great point about Kobe. We used to hate him, but these days we like him a lot more, having the frame of reference and maturity to respect what he’s done in the past and what he’s able to do at this point in his career. Younger me would murder current me if he read those words…but they’re true. There’s no one on this team that I can hang my allegiant purple flag on. They may be headed in the right direction, but that direction isn’t clear yet. And for the first time in my life, I’d rather watch a Spurs game than a Raptors game. It’s a sad day, and it’s no one’s fault. (wipes tear, makes unnecessarily dramatic Facebook update) The most important part of being a fan is loyalty. I get that. That’s how rivalries, dynasties, and reputations are built, cultivated by a caring fan base over multi-decades worth of 4-quarter intervals. But loyalty has its limits. The unspoken requirement for a sports fan to pledge blind allegiance to the cartoon logo of a multi-million dollar corporation is an anomaly in the Relationships of Life.™ If your spouse treats you poorly for long enough, you’re going to reconsider your relationship, at the very least. Same goes for parents, business partners, etc. Why do sports teams get an infinite leash? After a while, are you loyal for sticking around, or a sucker for staying put? I expect the comments section will have its share of “fair-weather fan” slinging, drawing first-blush ire that deviates into a stream of acronymic insults. But make no mistake, this is an important conversation to have. You can only be drunk on passion for so long. One day you too may wake up with an emptiness you can’t quite rationalize. You may find yourself cringing every time you read “Young Onez”. The Raptors aren’t fully to blame, and neither am I. Call it a third-life crisis. Call it a re-prioritizing of emotion. But be careful before you apply a negative label my way. As The Dude put it, “there are a lot of ins, a lot of outs, a lot of what-have-yous, man”. Life is complicated. Sports are complicated. Sometimes, the two get tangled. The greatest thing about the NBA is that there’s always a chance for redemption. Another 48 minutes around the corner. I don’t know if I’ll ever get back to my former level of involvement with the team. I hope I do. Thanks to PVR, the internet, the blogosphere, and countless other tools in the new Sports Swiss Army Knife, there’s never been more ways to find a reason to care. And I crave the connection. There’s no greater testament to sport than feeling in sync with thousands of people cheering, jeering, holding their breath for a glorious outcome. But I will tell you it has nothing to do with wins or Nike-sponsored smiles, and everything to do with one franchise and one fan – born at the same time, in the same place, recently disconnected but searching for a chance to be fused together again.
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Vray seems to be comming on quite well now, and includes ALSurface shader for SSS which is being integrated, as many know this is Arnold's best skin shader out there only faster in Vray. . The Vray documents are not good, and that's not because they are not complete yet, but because they don't help the new user learn. . It's more of a "what is this function " rather than. "this is how to use it" I can see cycles being a big hit as it has all the right ingredients being the developer, sharable materials, been through the trials in blender, price, 3 render nodes, fast cpu, gpu, nodal system. ... I've had a huge falling out with vrayc4d... is 3.25 ever going to get released? i just can't handle the horrendously slooooow updates simply cause it's not supported directly by chaos group. and yes... documentation is terrible too. it's a shame cause it's an incredibly fast render engine. I'm with you on this. Vray is an incredible renderer on every other platform. I wish Chaos group would just handle the integration instead of outsourcing it. It would be a much better scenario. Gone past 3.25, on 3.4 now. No it isn't I'm afraid. I mentioned that very test in my previous post. I'm interested in a side by side Cycles4D vs Physical. I'd hope Insydium would be working on a comparison. If I could get similar or even better render times out of CPU Cycles4D over Physical while being able to do GPU OpenCL previews on my iMac before switching to CPU for rendering on the Mac Pros that would be super convenient and I'd be up for a license. You cant compare CPU vs GPU, is not the same hardware, and theres no video card / processor chart comparison. This is something you need to test yourself with your own specs. Hopefully we get a demo so we can run our own tests based on our needs. What would be the CPU equivalent of 2 x 970 or 4x titans for example? In my own rig, doing tests, Octane is faster than Physical and Arnold, except if I need to render a million or more hair, then Arnold does the job faster. And if my scene is huge, Octane cant render it at all, while Arnold is in heaven when dealing with billions of polygons. Also, setting volumetrics and participating media in Octane is a pain in the butt, so Arnold wins because it is reliable, plus I love Arnold Utility nodes, and Octane lacks those. I have never found Physical Render accurate or physical at all, because their materials doesnt react the way they should, neither C4D lights do, and on top of it GI with Physical takes forever in my rig, so I dont really use it. "All the rendering was done using CPU rendering, on an Intel i7 3770 in a desktop with 12 GB of RAM and Windows 7. For Octane, a purely GPU renderer, an nvidia GTX 650 was used (*it performs very similarly to the Intel i7 3770)." Which is why I said it was what you were looking for, but you're right there's no comparison with the Physical renderer in C4D obviously. From my understanding Cycles is faster over CPU than the Physical renderer but we'll have to see. Those should give you an idea about performance per hardware. Also have a look at OSes Linux seems to be faster than Win in general.
https://www.c4dcafe.com/ipb/forums/topic/93824-cycles-for-c4d/?page=9
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Nurses’ experience with palliative sedation procedures in line with the 2005 Swiss guidelines: an exploratory study Many international studies have shown that the process of palliative sedation in an end-of-life context can be an adverse, even emo-tionally distressing experience for nurses. However, to the best of our knowledge, the experience of nurses working in palliative care in Switzerland has never been explored. The purpose of our study was, therefore, to understand and describe nurses’ experience with the process of palliative sedation in line with the Swiss guidelines developed in 2005. We opted for an exploratory qualitative monocen-tric study using comprehensive individual interviews to achieve this objective. A total of 10 nurses were approached, and nine agreed to take part. After the interviews were transcribed, eight were ulti-mately included in the analysis. This analysis shows that nurses’ attitudes toward the process of palliative sedation tended to be hesitant, resistant, or confident and that this was linked to the length of time they had worked in palliative care. These findings suggest that the 2005 Swiss guidelines do not protect nurses against the uncertainty related to process of palliative sedation. A national comprehensive multicentric study therefore needs to be developed to consolidate these results. iNtrODuctiON S edation in the broad sense of the term is an important practice and one that is critical in the field of palliative care (Cherny & ESMO Guidelines Working Group, 2014;Cherny, et al., 2009). However, from an epistemological point of view, there is no unique and universally accepted definition of this concept. A number of terms and expressions are used, and they are not all conceptualized in the same way, be it in the worldwide medical literature or in the recommendations for best practices issued at the national or European level (Abarshi et al., 2017;Gurschick et al., 2015;Schildmann & Schildmann, 2014). In Switzerland, a group of experts from the Swiss Association for Palliative Medicine, Care and Support published a set of formal guidelines for palliative sedation in 2005. In it, these experts chose to use the term "sédation palliative" (palliative sedation), defining it as the intentional administration of sedative substances at the minimum dosage required to relieve one or more refractory symptoms by a temporary or permanent reduction in consciousness of a patient with an advanced illness who is not expected to live beyond a matter of days or weeks and to do so in cooperation with a skilled, multidisciplinary team (Groupe d'experts de la Société suisse de médecine et de soins palliatifs, 2005, p. 1). These guidelines have since served as a framework for palliative sedation in Switzerland. A range of protocols and tools have been developed locally, in Swiss institutions providing palliative care, to allow these guidelines to be implemented. For example, the palliative care unit team at the Fribourg hospital (HFR) in Villars-sur-Glâne in the canton of Fribourg in French-speaking Switzerland developed a tool to monitor patients and meet the needs of the team in charge of the palliative sedation process in compliance with the 2005 Swiss guidelines (Francisco & Cantin, 2013). Although there are a few other studies on palliative sedation in Switzerland, they are essentially written from the perspective of doctors (Beauverd et al., 2014;Dumont et al., 2015;Foley et al., 2015;Ziegler et al., 2018). To date, we have found only one study in the databases we examined that addresses the issue from a nursing point of view (Tomczyk & Dieudonné-Rahm, 2019). The Swiss guidelines (2005), like other guidelines (Cherny & ESMO Guidelines Working Group, 2014;Cherny et al., 2009;Società Italiana di Cure Palliative, 2007; Société québécoise des médecins de soins palliatifs & Collège des médecins du Québec, 2016; Royal Dutch Medical Association, 2009) do not specifically define the role of nurses in palliative sedation. Yet, it seems to us that this role is essential at every point in the process. For example, during the initial phase, nurses can take part in team discussions, without making any decisions as these fall within the scope of physicians. Moreover, their role is critical in administering sedation, monitoring patients, and assessing their comfort. However, this type of involvement may be difficult for nurses to deal with and may even lead to a state of emotional distress, as has been shown in a number of studies (Abarshi et al., 2014;Lokker et al., 2018;Zuleta-Benjumea et al., 2018). Up until now, 1 to the best of our knowledge, the experience of nurses working in a palliative sedation context in French-speaking Switzerland has not been explored. The purpose of our study was therefore to understand and describe the experience of nurses in a palliative care unit providing palliative sedation based on the 2005 Swiss guidelines. By "experience," we mean "something personally encountered, undergone, or lived through" ("Experience," n.d.), bearing in mind that any such experience is inevitably subjective in nature. MAteriAls AND MetHODs The information about the experience of nurses in this regard was derived from interviews conducted during a previously published study on the conceptualization of palliative sedation (Tomczyk & Dieudonné-Rahm, 2019). This information spontaneously emerged from these findings and were the most dominant among them. This is a secondary analysis of these data (Brugidou et al., 2005). Consequently, with the exception of the subparagraph related to data analysis, the other subparagraphs below automatically refer to this conceptualization study (Tomczyk & Dieudonné-Rahm, 2019). This was an exploratory qualitative study based on comprehensive interviews (Blanchet & Gotman, 2010). It was conducted in accordance with the Consolidated Criteria for Reporting Qualitative Research -COREQ (Tong et al., 2007) over a three-week period, between October and November 2017. a) Legislative and ethical considerations In accordance with applicable Swiss legislation, this non-interventional study, which does not include the collection of any personal health data and does not directly concern patients, did not need to be reviewed by an ethics committee. The authorization of the head of the department where the study was being conducted was nevertheless secured, and the verbal consent of each participant was systematically sought out and obtained. Furthermore, participants all gave their consent for the interviews to be recorded using a sound recording device. In order for the department head and participants to be able to give their free and informed consent, the following information was presented to them: the study objectives, the nature of the information being gathered, the style of interview (a comprehensive interview with a secondary data analysis), the expected type of participation (type of questions and approximate length of the interview) and the reason for the request to take part in the interview. Participants were reminded of their rights, such as the right to refuse to take part in the study, the right to decline to answer questions and the right to terminate the interview without providing an explanation. It was also pointed out that no information that would make it possible 1 November 2017, March 2020. to personally identify the participants would be included in any publications resulting from this study. Lastly, interviewees were advised that this study was being conducted as part of Martyna Tomczyk's postdoctoral research. b) Study location The palliative care station at the Fribourg hospital (HFR), located in Villars-sur-Glâne in the canton of Fribourg in French-speaking Switzerland 2 was chosen as the study site for practical reasons. At the time the study was being carried out, the station was designated as a "qualité palliative" facility by the Swiss Association for Quality in Palliative Care. 3 It had 14 specialized beds and a day centre. c) Inclusion criteria There was only one inclusion criterion: being a nurse who agreed to take part in and who was available for the study. No restrictive criteria were imposed on participant selection. d) Inclusion methodology From the team of nurses working within the department, 10 professionals were chosen at random by their manager and asked to take part in an individual interview approximately 20 minutes in length. An inclusive approach spaced out over time was favoured. e) Preparation of interviews As these were comprehensive interviews (Blanchet & Gotman, 2010), an interview guide was not developed beforehand to "get informants to speak indirectly about the subject in order to ideally establish a conversational dynamic" (Kaufmann, 2011). As a result, participants were each asked a single question: "What does the expression 'palliative sedation' mean to you?" Information concerning participants' experience spontaneously emerged during the course of each interview. As needed, additional questions were asked, based on the interviewees' remarks, in an effort to ensure the data obtained were reliable. f ) Interviews The comprehensive individual interviews were all conducted by the same person, namely Martyna Tomczyk, a postdoctoral fellow in medical ethics, who had eight years of experience in qualitative research at the time these interviews were carried out. She had no reporting, family or other relationship with the head of the department or any of the participants. It was the first time any of them had met. All interviews were held in a private setting in an available room within the department (conference room, family room, etc.). The language used in the interviews was French, which was the common language for all participants, including the interviewer (first or second mother tongue or a learned language, given that the canton of Fribourg is a bilingual canton 4 ). All interviews were recorded using a sound recording device, with the consent of each participant. g) Preparation of interviews for analysis All interviews were transcribed manually and in a semi-verbatim format: repetitions were omitted to prevent the data and the corresponding analysis from becoming cumbersome. Any information that could potentially be used to personally identify participants was deleted. Only the length of time the subject had worked in palliative care was retained. The transcribed interviews were not sent to participants to review or edit. All sound recordings were erased once the interviews were transcribed. h) Analysis of interviews The process was one of thematic analysis and continuous thematization: themes related to the nurses' experience were identified and noted as each transcription was read. They were then categorized by central themes and subthemes, with which significant excerpts were associated. Finally, the interviews were analyzed transversally, based on previously identified themes and subthemes to identify points of convergence and divergence. The entire analysis was performed manually by Martyna Tomczyk. Out of a concern for scientific rigour and in an effort to reduce subjectivity bias, the interviews were analyzed twice more by the same person with a certain amount of time between each analysis. Adjustments from the second and third analysis were incorporated. The results following the third analysis were reviewed by Bernard Schumacher. results Ten nurses 5 were approached to participate in the study. Nine of these ten were available and did indeed take part. The saturation point was reached around the fourth interview; the subsequent interviews did not contribute any new elements, and each interview became more and more redundant (Alami et al., 2009;Mucchieli, 2004;Van Campenhoudt & Quivy, 2011). The study nevertheless continued up until the ninth interview in order to ensure the process was carried out with all due caution and diligence. Accordingly, nine interviews were conducted and submitted for transcription. During the transcription process, however, one interview had to be rejected due to the substandard quality of the sound recording. A total of eight interviews were, therefore, included in the analysis. The anticipated length of the interview was about 20 minutes, although it proved to vary from one interview to the next: the shortest lasted 12 minutes and the longest 52 minutes. The total combined length of the interviews was three hours and 14 minutes. The experience of the nurses interviewed was structured around three key and independent attitudes: hesitant, resistant, and confident. I. Hesitant Most of the nurses interviewed (6/8) expressed hesitancy about the process of palliative sedation and were unsure about the fundamental issue of patient comfort. a) Is the patient genuinely comfortable? Does the sedation fully relieve their suffering? The uncertainty as to the patient's comfort under palliative sedation was the main concern reported by the majority of nurses (6/8), as the following comment indicates: " b) Elements that further qualify the nurses' hesitant attitudes Two main elements that help qualify nurses' hesitant attitudes were identified, namely an in-depth assessment of a patient's situation by the healthcare team and the possibility and management of the assessment by the patient after they are taken off sedation. • Assessment of the sedated patient's comfort by the healthcare team (6/6): "When I do a sedation assessment, I always look at the patient's face. There's a certain amount of guesswork to be done. When someone is sedated… There are clinical signs that we can't observe, but the face… the face is a special thing… It's very unique. If they are suffering in any way, you can see it right away on their face, even if they're asleep. I don't know how to explain it… It's really quite mysterious… But it's always right there on their face. [...] For example, a patient might wince or screw up their face… That's a sign for us that they are in pain." (IDE No. 2) • Self-assessment of a patient's comfort, after they are taken off sedation (6/6): Personally, I am very relieved when a patient is taken off sedatives and can tell us how they were feeling. [...] Once they aren't sedated anymore, we ask the patient how they feel, how their experience being sedated was. That is very important for me. We can get their feedback. We can talk about it. For some of our patients who were in a great deal of pain and wanted to be sedated, once they were taken off the sedatives, they didn't want to go back on them. They didn't like the way the sedatives made them feel. They felt disconnected from their family. So, for them, this was a very important conversation to have. I think it's very important for them to be able to describe their experience." (IDE No. 4) To sum up, the main source of the hesitant attitude toward sedation was patient comfort. The comfort assessment, whether it is performed by the healthcare team when the patient is sedated or by the patient once they are taken off sedation, tended to mitigate this hesitancy. The comfort self-assessment was even more reassuring in that it helped eliminate the subjective component of a nurse-administered assessment. II. Resistance One nurse (1/8), who had worked the longest in palliative care, was resistant toward the process of palliative sedation. a) Is it appropriate to administer palliative sedation knowing that it does not relieve a patient's suffering? This nurse (1/8) was certain that patients' suffering was not relieved by palliative sedation, identifying this as their primary concern. The explanation offered was as follows: " III. Confidence One nurse (1/8), the one who had spent the least time working in palliative care, expressed confidence about the process of palliative sedation. a) A confident attitude toward palliative sedation The nurse reported a positive experience with regard to the use of palliative sedation and stated it was consistent with their own patient care values. Unlike the other nurses we interviewed (7/8), this nurse did not explicitly address the issue of relieving a patient's suffering. Here's what they had to say: "I don't feel like we're doing them any harm... the times I've experienced sedation have been a real relief. In my view, it's very much done with respect to the patient." (IDE No. 6) b) Main elements contributing to the confidence in the use of sedation Two elements were crucial in creating a positive sedation experience for this nurse: • Assessment of the patient's comfort during sedation by the healthcare team: "What's more, the assessment is done by us [...] It always has to be done using our chart." (IDE No. 6) • Self-assessment of the patient's comfort after they have been taken off sedation: "There's something that helps me personally, and that's when the patient is taken off sedation. After 24 hours, we stop administering the sedatives and we try to see the patient. [...] We always use this chart, which is a great source of support for us. [...] Taking them off sedation lets us see if the sedatives have been working. We talk to the patient. Sometimes, this first experience reduces their anxiety and we don't have to put them back on sedation. In those cases, it's a positive thing." (IDE No. 6) To sum up, most nurses were somewhat hesitant (6/8), even resistant (1/8), with regard to the process of palliative sedation. Both attitudes were largely attributable to the uncertainty surrounding patient comfort. There seem to be slightly varying levels of hesitancy, whereas resistance appears to be unalterable. On the other end of the continuum, one nurse had a fairly confident attitude toward the process and there seemed to be room for this confidence to grow even stronger. The above results have been summarized in Figure 1. DISCUSSION Our exploratory qualitative study, focused on the experience of nurses with palliative sedation administered in accordance with national guidelines in French-speaking Switzerland, is unlike any other study carried out to date. It essentially highlighted three categories of nurses' experience in this regard, one of which-hesitancy-dominated the others. In addition, it emphasized a link between experience and the length of time spent working in palliative care: more experienced nurses tended to be more hesitant, even resistant, in their attitude toward sedation, whereas the nurse who had spent less time working in palliative care was more confident in the process. The assessment of patient comfort by the healthcare team and the self-assessment by the patient was reassuring for all participants, except for the one resistant nurse. More specifically, most of the nurses interviewed were hesitant in their attitude toward palliative sedation, with one who was resistant. This was due to the uncertainty as to the relief that this method actually provided for patients' suffering. Although the goal of palliative sedation is to alleviate one or more refractory symptoms by reducing the level of consciousness (Groupe d'experts de la Société suisse de médecine et de soins palliatifs, 2005), it should be noted that it is not meant as a treatment designed to suppress the symptom(s) through pharmacological means acting on psychopathological mechanisms, but rather a treatment to reduce or eliminate the perception of the symptom(s) by altering awareness (Davis, 2009a). Although healthcare professionals have access to clinical observational scales such as the Critical Care Pain Observational Tool, the Behavioral Pain Scale and the Échelle comportementale de la douleur chez la personne âgée durant les soins, these tools have certain limits. These scales have been developed in other contexts and in most cases have not been validated in this specific situation. They are also, by definition, reliant on observation and therefore highly subjective and open to interpretation (Brinkkemper et al., 2013;Pudas-Tähkä et al., 2009). It has been demonstrated that assessments done by doctors differ from those performed by nurses and that non-clinical factors such as the religion and age of the caregiver can influence these results (Demertzi et al., 2009). In addition, although there are scales to assess pain and dyspnea, as subjective as they may be, tools that would make it possible to evaluate other physical symptoms (e.g., nausea) and, even more important, mental, existential, and emotional suffering 6 are lacking. However, reduced awareness brought on by sedation does not stop the brain from functioning, which is what potentially leads to anxiety, nightmares, and an altered perception of the environment. Scientific research on the topic is not abundant in the palliative care field (Davis, 2009b;Kon, 2011), but there are some studies on record in anesthesia and reanimation (Ghoneim, 2007;Ghoneim et al., 2009;Leslie et al., 2010;Sanders et al., 2012). It is interesting to note that, despite these limitations, the assessment was cited by the nurses interviewed as part of the study as a source of reassurance in the palliative sedation process. It should also be pointed out that the interviewees attached great importance to a patient's face when assessing their comfort, all while acknowledging that such a practice is difficult to defend scientifically. In an effort to enrich the discussion from an interdisciplinary perspective, we have turned to the field of philosophy to put forward a few elements to be considered. For example, Emmanuel Levinas emphasizes that the face is "not the mere assemblage of a nose, a forehead, eyes, etc." (Levinas, 1995, p. 20), but takes on a new dimension that transcends the idea we may have of the Other. The face "is not 'seen.'" It is "what cannot become a content" (Levinas, 2009, p. 81), which inevitably leads to something beyond the realm of factual knowledge. The face shows more than this and yet defies any attempt to define what that might be. The Other, as Levinas put it, "takes on the meaning of a face through the new dimension it opens up in the perception of a being. Through the face, the being is not only enclosed in its form and offered to the hand, it is also open, establishing itself in depth and, in this opening, presenting itself somehow in a personal way." (Levinas, 2009, p. 20). This relationship with the Other can be expressed in a very unique way when a person is experiencing the isolation of suffering and death: "Only a being whose solitude has reached a crispation through suffering, and in relation with death, takes its place on a ground where the relationship with the Other becomes possible." (Levinas, 1983, p. 64). The face never stops communicating, reaching out for a response from the caregiver, a response that falls within the 6 The potential differences among these three concepts go beyond the scope of this paper and have, therefore, not been expanded upon here. unconditional responsibility toward the Other: "answering the Other, which leads to vouching for them" (Levinas, 2009, p. 83;Pierron et al., 2019). Thus far, a patient's self-assessment remains a reliable method. Although it is impossible to use it in cases of deep and continuous sedation leading up to death, it is possible in cases of temporary sedation. Once the sedation has been discontinued, the patient can describe their experience. This approach, which is perfectly in line with the 2005 Swiss guidelines, was indeed a source of reassurance for all the nurses interviewed except one. It is noteworthy, however, that although deep and continuous sedation leading up to death was not specifically cited as a main purpose of the Swiss experts in this national document, it is a different story elsewhere in Europe. In fact, European experts actually recommend this type of sedation in certain well-defined situations (Cherny et al., 2009). Last but not least, it is important to discuss the experience of the nurse who, unlike the others, showed a resistant attitude toward the process of palliative sedation. This nurse considers it to be an inefficient practice in treating a patient's suffering, to the point of potentially making matters worse, and deemed it a hindrance to establishing a true caregiver-patient relationship, which they considered to be the only true way of easing suffering. First and foremost, it is important to emphasize that the "relationship between human beings," as Levinas puts it, "has an essentially non-synthesizable character." (Levinas, 2009, p. 71). However, it is certain that "true union or togetherness is not a togetherness of synthesis, but togetherness of face-to-face." (Levinas, 2009, p. 72). Yet, the relationship between the healthcare professional whose "power to act is, initially, greater than the Other's power to act" (Ricoeur 1990, p. 255) and the Other who is suffering -vulnerable and fragile -is by its very nature an asymmetrical relationship, hence the need to incorporate a certain reciprocity. Paul Ricoeur specifies that "reciprocity […] breaks away from the background of the presupposition of an initial dissymmetry between the protagonists of the action -a dissymmetry that puts one in the position of agent and the other in the position of patient" (Ricoeur, 1990, p. 255). If humans are "beings of reciprocity" (Malherbe, 1997, p. 26), this fundamental reciprocity manifests itself as "the shared responsibility of all human beings to keep their word to each other" (Malherbe, 1997, p. 29). For this philosopher, keeping one's word is "the goal, the destination and the means of reciprocity" (Malherbe, 1997, p. 26), which is consistent with what the interviewed nurse said during our study. The nurse emphasized that a relationship based on this is apt to soothe a patient's suffering. These remarks seemed even more interesting in that suffering is a universal, even existential, experience, linked to a pain felt within the body or perhaps independent of it (Perrot, 2016). A few decades ago, Cicely Saunders (1993), a pioneer in the palliative care movement, noted that presence and attentive listening in a caring environment can help soothe physical pain. Conversely, an analgesic can be inefficacious if suffering (mental anguish) is not addressed. In this regard, Verspieren (1984) asserts that the best cure for suffering is "a simple, genuine and deep relationship with the person who is sick" (p. 111). If such a relationship is indeed likely to be a form of care in and of itself, it is, to quote Aubry, "a very difficult type of care because there is no knowledge, strictly speaking, about what is causing the suffering" (Aubry, 2011, p. 230). Before concluding, it is worth taking a closer look at the four main methodological limitations of our study. First, it seems important to ponder whether retrieving information about past experience from the data from a study whose main goal was to discover and describe the conceptualization of palliative sedation by nurses is methodologically acceptable. The study did not openly address the question of experience. To answer this, we need to restate that the objective of the research on the exploratory conceptualization based on comprehensive interviews was not to explain a specific phenomenon but rather to engage us in the field to shed light on various facets of a highly complex reality (Alami et al., 2009;Paillé & Mucchielli, 2012). Nurses' experience was the dominant aspect. Additionally, the absence of an interview guide is something that can legitimately be called into question. We chose not to develop one so that the interview remained as open-ended as possible and allowed as many categories as possible to emerge. This approach is entirely consistent with the principles of qualitative research, comprehensive interviews in particular (Kaufmann, 2011). Lastly, the number of participants is likely to be criticized, although it does in fact comply with the principle of an exploratory quantitative study. In this type of research, population representativeness is not as important as the population's "social significance" (Alami et al., 2009). More specifically, the purpose of our study was not to know how many nurses have a given type of experience in the process of palliative sedation, but rather to bring out "transversal" categories to explore the study population via the individuality of each participant. It is also important to specify that the transcribed interviews were not sent to participants to review or edit. They were submitted directly for analysis. This approach was consistent with the objective of our main study (Tomczyk & Dieudonné-Rahm, 2019), which involved gathering conceptualizations from each nurse at a given moment, i.e., during the interview, by mental association in connection with their acquired experience at that point. The objective was not to verify theoretical or practical knowledge about palliative sedation or to assess practices within the department. Accordingly, editing participants' interviews would be contrary to the objective of the study and would in all likelihood bias the data and, by extension, the findings. Considering that this is an experience-based study, it would have been preferable for the transcribed interviews to be sent to participants (Ribau, Lasry, Bouchard et al., 2005). However, given that our study on nurses' experience resulted from a secondary analysis of the data, it was impossible for us at that stage to contact participants, due to the anonymity of the interviews, which may potentially constitute a methodological limitation. cONclusiON This study made it possible to understand the experience of nurses with regard to the use of palliative sedation in line with the 2005 Swiss recommendations and a protocol put in place to facilitate implementation. It shed light on categories to be consolidated and further developed in other studies. Beyond the nurses' experience, it would be essential to explore the experience of patients who have received temporary palliative sedation. The data from these future studies could be useful in updating the guidelines on palliative sedation and institutional protocols, for the sake of ensuring the best possible end-of-life care for patients and preventing the risk of emotional distress among nurses. cONFlicts OF iNterest The authors declare no conflict of interest or competing interests in relation to this paper. AcKNOWleDGeMeNts Our heartfelt thanks to Dr. Boris Cantin, head of the palliative care unit at Villa St. François in the Fribourg Hospital (HFR), and Sylvie Francisco, the nurse in charge, for making this study possible. The authors would also like to express their gratitude to the nurses who agreed to take part in the study.
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Google’s Paris headquarters have been raided as part of an investigation into the U.S. company’s tax payments, reports said. Around 100 tax officials and investigators from financial police are involved in the raid, which started at 5 a.m. local time, according to Le Parisien. Google is accused of owing France €1.6 billion ($1.8 billion; £1.3 billion) in unpaid taxes. The UK struck a £130 million settlement with Google earlier this year.
http://ghanaculturepolitics.com/googles-headquarters-in-paris-raided-over-tax-payment/
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Now is the time to listen to the people most affected by environmental injustice and racism — and the activists working to solve those problems. We've gathered 16 essential recent books about environmental justice, activism and related topics to get you started. The discovery of a lost plant species has revealed an "extinction hotspot" in Appalachia. Here's what scientists say should be done. Trouble's brewing in the Arctic — or really, thawing. Rising temperatures are warming the region's permafrost, triggering the release of trapped greenhouse gases. How close are we to a dangerous tipping point? Author and ethicist Harriet Washington's book, A Terrible Thing to Waste: Environmental Racism and Its Assault on the American Mind, explains why the fallout from environmental toxicity isn't just physical. Read our interview with her here. Miami is facing an existential crisis due to climate change. A new book investigates whether it can make a just transition in the face of its climate woes and what that means for the rest of our cities. Photo of Black Lives Matter protest by Elvert Barnes.
https://www.biologicaldiversity.org/publications/emailarchive/viewemail.php?email=Essential%20Environmental%20Justice%20Reads2020-06-18T12%3A05%3A37%2000%3A00
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It's funny that you mention that - when I read your post I said "boy, Gascoigne was really easy!". I actually killed him with the axe. But your problem actually supports my original point. I have observed the exact same behavior when I handle bosses. My first couple of fights with a boss are generally good, then they get much worse when I start "thinking". Finally, they get better after my thinking becomes a new strategy. I went to Gascoigne with no strategy or thinking. Just dodge, hit, dodge hit and try staying behind the tombstones to protect myself against the guns. I think that you might at this point be psyching yourself out as you say... Have you tried grinding a little to level up?
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2) You can assign a "application specific" password to both your Obi Portal AND you Obion device. Not sure about you guys, but I don't trust *anyone* with my password. This solves both problems. I can restrict access that Obihai has, but I can allow it to still work.
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The Educational Psychology team is hosting weekly drop in sessions for SENCOs to support the conversion from statements to Education, Health and Care Plans. Full detalils of dates and venues are available on the dedicated Documentation for Conversion: Annual Reviews page. Please click the link Workshop dates once you get onto the page. These are drop in workshops, not training sessions. They offer the opportunity for SENCOs to bring along any conversion that they are struggling with and work this through with a member of the EP team. These sessions are in addition to the 3 hour training session which SENCOs should attend in the first instance. A list of dates for the initial 'refresher' training is included at the bottom of the list of workshops.
https://bso.bradford.gov.uk/news/9907-ehcp-conversion-workshops
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I offer you Premium quality whole hazelnuts to rediscover the true taste of hazelnuts in its simplest expression. As a snack, as an aperitif or in all your sweet and savory recipes, make wonders with exceptional hazelnuts. The hazelnut is a fruit very appreciated by all, from the greediest to the most athletic. However, be careful not to abuse them. If they are perfect in the framework of a healthy diet, it is advised not to abuse them. 30 g per day are enough to benefit from the virtues of this oleaginous fruit. To preserve both your health and to give you a unique taste pleasure, I suggest a whole Premium unsalted hazelnut. Find the real taste of hazelnut with an unprocessed dried fruit. Where does the whole hazelnut come from? The hazelnut comes from the common hazelnut tree, a tree found in France and in many other countries around the world. The hazelnut tree is a shrub in which an involucre develops, a green envelope that we find in clusters called "trochets" containing 2 or 3 hazelnuts. In October, we collect the achene shell which contains a hazelnut. Put away your nutcracker, I offer you whole shelled hazelnuts that you can taste as soon as you open the package for the most impatient among you. Did you know that? Even if you eat a hazelnut, the edible seed is called "almond". The hazelnut is not a dry fruit that can only awaken your taste buds. It is also an oleaginous fruit that acts in favor of your health. - vitamins and minerals. Discover the nutritional values of hazelnuts, a real argument in favor of this dried fruit. The hazelnut helps to fight against bad cholesterol and its high content in dietary fiber helps to take care of your transit. Able to increase the feeling of satiety, the hazelnut is not the enemy of your weight, quite the contrary according to some scientists. My high quality whole hazelnuts are the partners of gourmets, gourmets, but also of sportsmen. With more than 600 calories per 100 g, they are perfect for gaining weight with healthy and natural products. For a healthy snack before and during exercise, these hazelnuts rich in essential fatty acids can also be included in a high-energy smoothie. Hazelnuts can be eaten raw, in a dish, a dessert or processed. When you buy a natural whole hazelnut, you have complete freedom as to how you use your dried fruit. You can roast it, grind it, make hazelnut butter and explore all the possibilities offered by this oleaginous fruit. - mushroom salad. Goji blend "Greedy and Tonus"
https://www.davidvanille.com/en/dry-fruits-and-seeds/482-6212-whole-hazelnuts-premium.html
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Lawyers for Bibi Sharima-Gopaul and her former partner Jarvis Small, the two persons found guilty of murdering 16-year-old Neesa Gopaul, yesterday argued that several irregularities may have led to their conviction. The article Judge’s directions to jury, sentencing come under scrutiny at appeal hearing for Neesa Gopaul murder convicts appeared first on Stabroek News.
https://caribviberadio.com/judges-directions-to-jury-sentencing-come-under-scrutiny-at-appeal-hearing-for-neesa-gopaul-murder-convicts/
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Children are born associating mom with food. Sometimes we try to separate ourselves as mothers from being the constant need to be the food person. Through nature and because of nurturing: we are it. I have also noticed, that there is really no homey feeling of comfort, warmth, or family bonding when we as mothers, are not there providing meals and food for our families in a nurturing way.
https://mothers-who-know.blogspot.com/2012/05/proclamation-series-nurturing-our.html
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If you’ve been putting off blogging, there’s no good reason to keep delaying. Blogging is done by a lot of business people every day, for the main reason that it helps generate traffic to company websites. Sure, it’s a lot of work, but so is everything that’s worthwhile in this world. If you’re willing to put in the effort, running a blog is not an issue. If you’re brand new to blogging, you may want to start with selecting a fully managed WordPress host. That way you can rest assured that your WordPress installation is up to speed and safe from hackers. WordPress is a robust blogging platform, but because it’s so popular it tends to be a target of many hack attempts. A web host that specializes in secure WordPress hosting can help you lock everything down. Once you’re up and running, the rest becomes very easy to do. You can choose a template, install whatever plugins you want, and go to work on the important task of creating content for your new blog. Follow the keys to blogging success and you can expect to generate a decent amount of traffic to your website. Running a professional blog takes dedication above all else. You can’t expect overnight success with a blog, it just generally won’t happen. If you have a strong social media presence, then perhaps you can generate traffic quickly, but if you’re just starting out with social media, you can’t expect too much traction at first. For that reason consistency and managing your expectations is important early on. WordPress is extremely flexible. You can build whatever type of blog you want, you can even add eCommerce if you choose. The choice is up to you. The bottom line is, WordPress is a platform. It’s up to you to use the tool in the manner you see fit. Follow the strategy you outline and your blog can serve to help you achieve your business goals. If you want to use your blog for lead generation, you can. Add a newsletter sign-up form to your sidebar. If you want people to call you, end every post with a phone number. You need to think of the call to action you want to convey, and then implement it. If you’re blogging about a certain theme, stay on-topic and write as many helpful posts as you can. The best way to learn blogging is by jumping in and doing it. You won’t need to do all that much learning to get your blog moving. Don’t be all about text either. People don’t love reading as much as they used to. Make sure to be liberal with image files and videos. Most importantly, take to the social networks to promote your blog. Growth won’t happen on its own. You have to engage with people and find out what they’re interested in. Once you do, you can deliver it to them. Blogging success only happens when your content is customized for your target audience. Thanks for stopping by and reading and good luck with your blog!
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2015 is going to be an amazing year for Disney films. Disney will release THE AVENGERS 2, PIRATES OF THE CARIBBEAN 5, STAR WARS: EPISODE VII and now, FINDING DORY. It was just announced this morning that the sequel to 2003’s Oscar®-winning film FINDING NEMO will be released in theatres everywhere on November 25th 2015. Disney/Pixar’s FINDING DORY Dives into Theaters November 25th 2015. Ellen DeGeneres, the Voice of the Beloved Blue Tang Fish in 2003’s “Finding Nemo,” Shares Plans for the All-New Big-Screen Adventure.
https://www.fabulousmomblog.com/disneypixars-finding-dory-dives-into-theaters-november-25th-2015/
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The Burrator Inn is a highly welcoming, 'proper pub' with comfortable rooms, based near the ancient town of Tavistock on wild Dartmoor. The Burrator Inn - or Burrie to locals - has been an established presence for over a century. Situated just 1 mile from the famous Burrator Reservoir, it's a short drive from Tavistock with all its history and boutique shops. The handsome, well appointed building leads to a clean, traditional bar area where guests can enjoy a pint of real ale from the likes of St Austell. Cask Marque accredited, the Burrator Inn is also featured in the CAMRA Real Ale Guide 2019. For those that wish to dine, food is served from midday to 9pm every day. The menu offers every pub classic that guests could wish to hope for, with generous portions at decent prices. Children and vegetarians are catered for, and they also offer a Community Lunch for older residents. Upstairs, guests will find five different rooms, ranging from family rooms plus a King sized double and a twin room. All are comfortably furnished to create that home-from home-experience, complete with newly refurbished en suite bathrooms and breakfast. Located in the stunning Dartmoor National Park, The Burrator makes a great base for exploring everything that Devon has to offer. From country walks to cream teas at nearby National Trust property, Cotehele. The pub itself hosts one very popular Open Mic night each month. For those seeking brighter lights, The Burrator Inn is just 12 miles from Plymouth City Centre, on the B3212.
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package uk.gov.gds.ier.transaction.overseas.dateLeftUk import uk.gov.gds.ier.transaction.overseas.InprogressOverseas import uk.gov.gds.ier.step.StepTemplate trait DateLeftUkMustache extends StepTemplate[InprogressOverseas] { val title = "When did you leave the UK?" case class DateLeftUkModel( question:Question, dateLeftUkFieldSet: FieldSet, dateLeftUkMonth: Field, dateLeftUkYear: Field ) extends MustacheData val mustache = MustacheTemplate("overseas/dateLeftUk") { (form, post) => implicit val progressForm = form DateLeftUkModel( question = Question( postUrl = post.url, errorMessages = form.globalErrors.map{ _.message }, title = title ), dateLeftUkFieldSet = FieldSet( classes = if (progressForm(keys.dateLeftUk.month).hasErrors || progressForm(keys.dateLeftUk.year).hasErrors) "invalid" else "" ), dateLeftUkMonth = TextField(keys.dateLeftUk.month), dateLeftUkYear = TextField(key = keys.dateLeftUk.year) ) } }
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Digital’s Equipment Corp’s new DECpc AXP 150 is not the machine for people that want to run shrink-wrapped Windows applications quickly. Although the Insignia Solutions Ltd-sourced MS-DOS and Windows emulation enables users to run existing iAPX-86-based applications without modification, they run on the UKP5,350 Alpha RISC based machine at Intel 80386 or 80486 speeds. It is not intended as a mass-market machine, says Dennis Saloky, DEC’s marketing programmes manager for NT. Instead he positions it as a developers box and claims that demand is strong. It is these developers, of course that DEC will depend on to produce the the Alpha-compiled NT applications that will deliver the high performance promised by the processor. For the mass-market boxes, wait until the autumn, says Saloky, when the company is likely to launch lower priced Alpha PCs with comparable or perhaps higher performance. The cheaper RISC-based machines are likely to impinge directly on the territory occupied by the company’s newly announced Pentium machines. In fact, assuming that Pentium pricing stays constant, the new machines will offer comparable pricing and higher performance, says Saloky.
https://www.cbronline.com/news/first_one_is_for_developers_dec_plans_cheaper_powerful_alpha_pcs_later_this_year/
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Taiwan Excellence, the symbol of Taiwan's highest honour for high-quality products, will be showcasing 10 award-winning brands at the upcoming ARCHIDEX 2022, held between 29th June to 2nd July at Kuala Lumpur Convention Centre (KLCC). Throughout the exhibition, Taiwan Excellence will focus on two categories: kitchen and sanitaryware and interior and building creations, with the theme "Modern Living Redefined." Smart technology, remodelling materials, and home and commercial solutions will be among the brands on display at the expo. These product launches are intended to market and explore potential collaborations with Malaysian counterparts. JUSTIME’s Sheng Tai Brassware Co. Ltd. is a world-famous premium brand for water faucets, showers, and accessories. The company has been servicing its clients since 1976, and throughout the years, the firm has won numerous international design accolades, including the Red Dot Design Awards, iF Design Awards, IDEA, Good Design, Architizer A+ Awards, and Taiwan Excellence Awards. According to Chinger Pan, Marketing Director and Chairman of Sheng Tai Brassware Co. Ltd., the JUSTIME brand has grown by leaps and bounds since the company's introduction into the Malaysian market four years ago. "To increase its brand visibility during the pandemic, we have transitioned into the online business strategy by setting up an online shop, website, and social media. After the pandemic, we've been planning strategic brand collaborations and cross-industry promotions with developers and interior designers," Chinger explained. The Pan 2 Series faucets are their most recent offerings. In comparison to typical faucets, these items are available in rectangular or circular shapes to accommodate various types of basins and consumer preferences. "Pan-" is a Greek word that signifies "all". "We are delighted to bring this latest product to our customers, and we hope they will have the opportunity to experience our high-quality products beginning with this Pan Series, which can be used on a variety of basins and bathroom designs," Chinger added. Filroot by Plainliv Taiwan Co. Ltd. is a brand that specialises in a variety of water filtration systems. Manufactured in Taiwan, their revolutionary water filter design has won multiple honours, including the Taiwan Innotech Expo, Red Dot Design Award, iF Design Award, and MUSE Design Awards. "We meticulously choose and develop the Filroot product as if we were doing so for ourselves and our families," says Sue Chan, Marketing executive at Plainliv Taiwan Co. Ltd. “We look after your and your family's safety and health by setting a high standard for household water quality." Their water filtration technology is a ground-breaking Modular Filter Cartridge that can eliminate up to 99.99% of bacteria from tap water and produce pure drinking water. The module is available in a variety of filter combinations such as reducing chlorine and trihalomethanes, eliminating sand, rust, odour, colour, and chemicals in water, and removing undesirable tastes. The Filroot water filtration design comes from an array of bricks. Water purification, like an array of bricks, requires multiple combinations of water treatments depending on the water quality. The water treatment methods have been built into different modules or filter cartridges, such as Polypropylene, Active Carbon, Ultra Violet, Ultra Filtration, Reverse Osmosis and more. Because the waterway and filter cartridge are connected in one module, the filter can be replaced in a few simple steps. The user-friendly design enables customers to adjust their water purifier features whenever they need to. Meanwhile, the sleek and compact form makes it suitable for any home. Taiwan Excellence is the name that carries the honour of Taiwan’s premium products, it is the symbol of recognising outstanding and innovative products from Taiwan. Companies that have been nominated for the annual Taiwan Excellence Award have exceeded the tough judging criteria and process. The prestigious award, established by the Ministry of Economy in 1992, is recognised by 102 countries worldwide. Taiwan Excellence will present two online talks at the ARCHIDEX Online 2021 expo, highlighting ten of their award-winning products. The Shaping Healthy Design with Innovation webinar explores how home products have become smarter as technology and design have been integrated. Qanvast SuperTrust 2022: Recipients Announced!
https://qanvast.com/my/articles/taiwan-excellence-to-showcase-award-winning-brands-at-archidex-2022-2871
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Fear isn’t something to overcome, ignore, hold onto, or tough out. It is a feeling, and, like all feelings, you acknowledge it. You work through it. You thank it for what you’ve learned and what you’ve gained. And then you let it go, knowing that the feeling will come and go when you need it. Feel the fear and do it anyway. And make it a great week.
http://elaaktay.com/2018/11/26/monday-mornings-121/
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Wondering what’s in the cards for the year ahead? I gifted myself a stunning new deck (info below) and immediately pulled a five-card spread for our 2022 conversations. The cards point to continued cultivation of our inner knowing from a place of self love. The best way to invite these vibes is via deeply moving chats. Enter Moin Subhani, a Toronto-based psychotherapist who practices the Gestalt method. Our discussion about the “everything-ness” of Gestalt, a modality he calls “applied Buddhism,” is revelatory – especially for those curious about the structure of this somatic practice and anyone grappling to stay rooted in the present while addressing traumas of the past. That’s about 99.9% of my fellow wounded healers. “In Gestalt, we say lose your mind, gain the senses,” says Moin, who’s currently waiting out the cold and the ick in Mexico (and I’m moving in!). He likens the modality to emotional intelligence 101, an awareness of intra- and interpersonal truths. That inward/outward journey is one Moin knows well. ”Growing up in this society, especially as a Brown person, queer, it was hard for me to sit comfortably in my skin and love myself.” His corporate career made the task doubly difficult. In a setting where the aggressive male stereotype is at best tolerated and at worst celebrated, any show of displeasure or vocalized anger by a person of color is generally deemed a threat to rigid roles and accepted strategies for overpowering challenges to the reigning authority. Moin feels that Gestalt fosters a more thorough unlearning and rewiring process. In an age of accelerated global reckoning, where our anger is regularly misunderstood or aggressively disregarded, there’s promise in reclaiming our anger as power with rather than power over. Moin Subhani is a Registered Psychotherapist. As a therapist, Moin is compassionate, creative and playful. He completed his psychotherapy training at the Gestalt Institute of Toronto and is a life-long student of Eastern Spirituality.
https://headhearttherapy.com/179-moin-subhani-unlearning-rewiring-and-reclaiming-our-power-with-gestalt-method/
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If you’re looking for cancer information and resources in Missouri you’ve come to the right place. From our local fundraising events to our cancer support programs, you’ll find everything you need to fuel the fight against cancer and get patient support – right here in our community. The American Cancer Society has programs and services to help you manage cancer treatment and recovery and find the emotional support you need. And best of all, our help is free. Find programs and services in Missouri. We’re activists leading the fight for a world without cancer in Missouri. Find a walk in Missouri and help us fight breast cancer. Attend a fun-filled event to help fight cancer in Missouri. When you volunteer with the American Cancer Society in Missouri, you’re helping to save the lives of people in your community – and around the world. It only takes a little time to do a whole lot of good. Sign up to volunteer today. In the American Cancer Society’s Cancer Statistic Center, you’ll find information about Missouri’s cancer incidence, mortality, and survival rates, screening metrics, and risk factors.
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Last week, the Brownback-Weldon bill to prohibit human cloning was introduced on Capitol Hill. And the arguments against it are ... well, as it turns out, there really aren't many arguments against a ban on manufacturing human beings like gingerbread men from a cookie cutter. It's true, of course, that some propositions resembling arguments for cloning have been advanced in recent years. But under scrutiny, these ostensible arguments quickly dissolve into a fog of vague, unfocused feelings about science, sex and the human condition. Take, for example, the claim that to prohibit cloning would be to prevent a grief-stricken mother and father from replacing their dead daughter with a new, genetically identical daughter who will somehow erase the loss of their first daughter. You don't have to delve very far into philosophical questions of identity and existence to realize that the notion is so confused and self-contradictory, it won't even bear the weight of its own expression. But the point of invoking those grieving parents is not to present an argument. The point is to express a feeling: Death ought not to sting, the grave should not have the victory, the ones we love must come back to life. And so cloning enthusiasts look to science — as to a god — to wipe away our tears, to assuage the eternal pity and to console human grief. Or take, for another example, the claim that a ban on human cloning would be a blow against Roe v. Wade. Some anti-abortion activists do make this argument. They say everything bad begins with a disrespect for human life: The unfettered right to abortion grants us a Promethean power of life and death over our unborn offspring that naturally leads to practices like cloning. Thus, the argument goes, we can succeed in banning cloning only by winning — today — the battle over abortion. Many supporters of cloning actually make the same argument, although they run it in reverse to frighten off liberal Democrats: A ban on cloning, they warn, would mean the loss of "a woman's right to choose"; America can thus guarantee the full abortion license only by allowing cloning to proceed unhindered. Our fellow pro-lifers may well be right that there is an underlying logic linking these issues. But the truth is — and this is the vital political point — we can ban cloning without touching Roe v. Wade. Indeed, the debate over cloning shouldn't be forced back into the well-worn grooves of the abortion debate. The issue of cloning offers the possibility of some interesting realignments in American politics. This is an issue, after all, on which radical environmentalists and religious evangelicals find themselves in agreement — which would be impossible if the right-to-choose equals right-to-clone argument were definitive. But then, this was never meant to be a genuine argument. It is meant instead to express a feeling — a feeling that radical individualism, sexual liberation and modern science have all somehow combined to bring us to this point, and to reject any piece of it now, even the reproduction of human beings by cloning, is to return to the Dark Ages. And take, for a final example, the claim that a law against cloning human beings will make us forfeit potential advances in medicine. Who could be opposed to experiments that might lead to a cure for cancer, a fully compatible liver for transplanting, a genetically engineered solution to diabetes? But examined more closely, the hoped-for medical advances turn out to be merely examples of things that researchers promise they will try to find, if only we leave them alone to play with human cloning as much as they like. The manipulation of stem cells obtained from cloned embryos is asserted to be necessary for the desired medical breakthroughs. And the use of these putative therapeutic miracles in pro-cloning arguments seems to have survived unscathed despite the recent evidence that it is possible to obtain the required stem cells not from embryos but from adults' blood, bone marrow, brain tissue, and even fat cells. It has survived unscathed, for that matter, the disastrous initial results of stem-cell treatment (in which the cells, derived from embryos, went wild and began producing not merely brain tissue but other tissue as well when introduced into the brains of some of their new hosts). But then, the promise of unlimited medical advance was never really an argument for keeping cloning legal. It is a feeling, a sentiment, masquerading as an argument — and perhaps the most insidious of them all. A vague belief in the capacity of human beings to obtain any end through beneficent science has oddly joined a vague belief in the incapacity of human beings to halt the march of science or decide what those ends should be. Once we add in the thousands of university laboratories anxious for the acclaim of scientific breakthroughs and the dozens of large pharmaceutical companies hungry for new technologies, the use of cloning simply feels like the future: unavoidable, inexorable and predetermined. Might as well oppose the rising of tomorrow's sun, we are counseled, as try to halt the arrival of human cloning. Yet halt it we can, and should — for reasons compellingly presented by such thinkers as Leon Kass and Gilbert Meilaender. Those reasons range from the extraordinarily high incidence of deformity among cloned animals, to the familial confusion that will be engendered by reproducing oneself as one's own child, to the likely psychological damage to the person created by cloning, and, most fundamentally, to the fact that moving from the begetting of our children to the manufacture of our descendants is a radical and perhaps irreparable dehumanization. American politics being what it is, there will be an attempt to find a "compromise" on this issue, as there was when Congress last considered it in 1998. The favored form of compromise prohibits "reproductive" cloning while allowing "therapeutic" cloning to continue unabated. But a ban solely on reproductive uses only looks like a compromise. It's actually a victory for the pro-cloning forces — and everyone opposed to the onslaught of human cloning must reject it out of hand. For what this "compromise" would mean is a license to practice all the cloning a scientist may desire, while vainly attempting to prevent the end toward which that practice clearly aims: The live birth of cloned human beings. Part of the problem is the question of intention. Since all embryonic clones are made in the same way, we cannot know the reason for which an embryo was created until it is either destroyed in research or implanted in a womb. Of course, once it has been implanted, a law against reproductive cloning would clearly have been violated. But there is at that point no possible redress, short of forced abortions or a federal pregnancy police determining how each pregnancy in America came about. Then, too, there is the problem of the status of the embryos created by cloning. For those who are pro-life, of course, the embryo and the fetus are already members of the human race, and it is wrong simply to destroy them. But even the federal directives for biological research, which do not admit the personhood of embryos, nonetheless demand that they be treated with "profound respect." And a law banning only reproductive cloning would produce, for the first time in federal statutes, a class of embryos it is a crime not to destroy, a class of embryos that must not be treated with profound respect. Recent events in England are instructive. On April 19, Health Secretary Alan Milburn announced, to great fanfare in the British press, that Britain would shortly become the first country in the world to ban human cloning. But all he really meant was that Britain would prohibit reproduction by cloning, while continuing to promote the actual practice of cloning by encouraging laboratories to perfect their techniques. It was as polished an example of studied disingenuousness and blatant obfuscation as one will ever see. Four days later, the head of Britain's embryology authority quietly announced that scientists who had gone abroad to do embryo research illegal in Britain could return to "continuing acclaim." For America, the lesson is clear: The only way to stop human reproductive cloning is to ban all human cloning, and to ban it now. There is no middle ground here, not merely because the principles involved do not admit it, but because the actual practice grants no room for compromise. To allow human cloning for medical and biological research is necessarily to allow — in the very near future — cloning for the reproduction of human beings.
https://www.foxnews.com/story/lawmakers-should-ban-all-human-cloning-now
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It feels weird saying this but I really like Kobe now. Its been cool seeing his tweets and his interviews. His whole persona/personality is getting more relaxed and he's funny/entertaining And the past 3 games with him changing his whole identity is amazing to me. Kobe more assists that FGA #isthisreallife I can for the first time say that I have enjoyed watching the Lakers play. I am semi hooked on their ups and downs in each game. seeing each night how they'll play. New Kobe fan, Idk if i'm allowed in Spurs churches now lol
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Not this building or a building but I looked at a house 2 weeks ago the person showing it was smoking in it the house wasn’t updated sense 1974 it was dirty and needed a lot of work weren’t allowed to use the bathtub only the shower because it was a jet tub and if it broke he didn’t want to fix it he wanted 2300 a month and said the price reflects the condition of the home he said a handful of times he wasn’t putting any money into the home to rent it out for 2300 a month when apartment buildings were getting 2150 a month 🤦‍♀️
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3 edition of Genealogies of William French Burrows and Annie Libby Burrows found in the catalog. Burrows, Annie Libby, 1858-1940 -- Family. Statement compiled by Louisa Libby Burrows ; edited by Arthur Andrews Burrows, 3rd. Historical Person Search Search Search Results Results David William BURROWS ( - ) Try FREE for 14 days Try FREE for 14 days How do we create a person’s profile? We collect and match historical records that Ancestry users have contributed to their family trees to . Burrows family | Genealogy, family tree and origins. See the list of all Burrows. BEGIN MY FAMILY TREE (FREE) FIND A PERSON (FREE) Marriages of the family Burrows (To see all marriages, register for free) William Burrows: Lucy Brommell: Montreal, Qc; John Burrows: Ann Fierney: Richmond, On; Edouard Murray: Marie Burrows. Get this from a library! Burrow family history. [James Rightman Blanks] -- John Burrow, who was born about , is believed to be the origin of a number of the Burrow families found in Virginia and North Carolina. He died in Records indicate that his wifés name may. Born in Ipswich, Essex, Massachusetts, United States on 30 Nov to Thomas French and Mary Scudamore. William French married Abigail Gilman Wiggin and had 10 children. He passed away on 15 Nov in Stratham, Rockingham, New Hampshire, United States. FHL Book Prdc v. 2 [King William County appears in Vol. 2 Part 3] [Page] Rutherford, Dolores Crumrine. The Page Family in Virginia Personal Property Taxes (). 2 vols. Carmichael, Calif.: D.C. Rutherford, FHL Book Prd v. [King William County appears in Vol. 2] [Palmer] Palmer, Russell. Family Tree Maker user home page for Billy-R-Burrow. Buy Genealogies of William French Burrows and Annie Libby Burrows by Louisa Libby Burrows (ISBN:) from Amazon's Book Store. Everyday low prices and free delivery on eligible : Louisa Libby Burrows. Genealogy of William French Burrows [Louisa Libby Burrows] on *FREE* shipping on qualifying offers. An illustration of a magnifying glass. Genealogy of William French Burrows. Item Preview remove-circle. Sponsor a Book. Burrows family 19 works Search for books with subject Burrows family. Genealogy of Annie Libby Burrows Louisa Libby Burrows Read. Genealogies of William French Burrows and Annie Libby Burrows Louisa Libby Burrows Read. The Peters family genealogy Martin D. Peters. See what's new with book lending at the Internet Archive. A line drawing of the Internet Archive headquarters building façade. An illustration of a magnifying glass. An illustration of a magnifying glass. An illustration of a horizontal line over an up pointing arrow. Genealogy of Annie Libby Burrows Item Preview remove-circle. Title: Compiled by Louisa Libby Burrows, Edited by Arthur Andrews Burrows, 3rd, Genealogies of William French Burrows and Annie Libby Burrows (MCMLXX) Page: Pages Source: S 6. Title: N. Historical Genealogical Register Page: Vol. 24, Page Source: S 7. Title: National Society of Colonial Dames of America. Open Library is an open, editable library catalog, building towards a web page for every book ever published. Read, borrow, and discover more than 3M books for free. 1 Burrows, Louisa Libby, Genealogies of William French Burrows and Annie Libby Burrows, Syracuse, NY: Salina Press (), 2 Cutter, William Richard, Historic Homes and Places and Genealogical and Personal Memoirs Relating to the Families of M iddlesex Co., Mass., Vol. 1, New York: Lewis Historical Publishing Company (), Annie Burrows was born in Suffolk, England, to parents who loved to read. Her home was always full of books, and every Saturday they went to the local library to stock up on more. Always a bit of a daydreamer, Annie began to make up stories in her own head during long walks to and from school, and during the prolonged bouts of illness that kept. The first Burrows to settle in the United States was John Burrows, arriving in Virginia in Other noteworthy people from the Burrows genealogy include filmmaker David Burrows, session singer Tony Burrows, English actress Saffron Burrows, Welsh operatic tenor Stuart Burrows, comic book artist Jacen Burrows, and Australian jazz and swing. William Burrows was born circaat birth place, to William Burrows and Ann Burrows. William lived inat address. 4 of 14 documents 1 of 14 documents View all. differentiate from "french". it is intended as a finding aid, assisting researchers on both sides of the atlantic to discover either where their ancestors came from or where they emigrated to. Genealogy profile for William Burrows William Burrows ( - ) - Genealogy Genealogy for William Burrows ( - ) family tree on Geni, with over million profiles of ancestors and living relatives. La Grande, Oregon Luke Burr of La Grande, died Oct. 10 at his home. A full obituary will be available later. Loveland Funeral Chapel is in charge of arrangements. La Grande Observer – Octo _____- Luke Burrows La Grande Luke Burrows, 72, of La Grande, died Oct. 10 at his home. Burrows, Charles William; born, Hollis, York County, Me., Dec. 21, ; son of Joseph W. and Mary Elizabeth Atkinson Burrows; graduated, Ti. Military Academ. Genealogy for William Fraser Burrows ( - ) family tree on Geni, with over million profiles of ancestors and living relatives. People Projects Discussions Surnames. genealogy book "genealogy of wm french burrows", leather bound, photo & signature, 75pp w/family name index gilt edge mint condit tipt in papers & letters, genie charts, gen of annie libby burrows also incl, contact us 4 details & more info aa -- $ Annie married William Burrows. Annie passed away on month dayat age 62 at death place, Utah. She was buried on month day 4 of 9 documents 1 of 9 documents View all. Ann Agnes Burrows (born Janosov), - Ann Agnes Burrows (born. Frederick William Burrows second son of seven and third child of eleven children born to Harriet America Shekell & Samuel Frederick Burrows. Frederick William Burrows was the grandson of Elizabeth Dellinger & John Henry Burrows, Sr. and Harriet Augusta Bohrer & Richard Richardson Shekell Frederick William Burrows. Explore genealogy for William Burrows born bef. Gloucester, Gloucestershire, England, United Kingdom including ancestors + more in the free family tree community. login William John Burrows (bef. Annie Carlile 5/16/ Re: Looking for Christopher Burrows he was a Canadian Mountie many yrs ago ZOAR BLAIR HENRY, OHIO. mark henry 12/31/ Daughter Looking for William Burrows (Father) AnnMarie Burrows- Stenger 6/22/ burrows/shelmerdine post. carly mccarrolli 8/11/ Betty A Burrows married to Jack Reeve susan murton 9/12/"Genealogy of William French Burrows," compiled by Louisa Libby Burrows. Hammett Papers by Abraham Hammett, Early Inhabitants of Ipswich, Mass "Cabbages and Kings," by Ned Brown. "The Pioneers of Massachusetts," by Charles H. Pope, "History of Newburyport." No further identification of this source was provided.William W. Barrows 23 Jun Spencertown, Columbia, Edith Annie Barrows abt Fishtoft, Lincolnshire, England, Harmony (Barrows) Burrows 07 May Mansfield, Tolland, Connecticut - 29 Mar managed by Teresa Downey. Herbert Palmer Barrows 08 Jul Tolland.
https://nutezezitikubug.simplicityhsd.com/genealogies-of-william-french-burrows-and-annie-libby-burrows-book-33444jl.php
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STEPANAKERT, JUNE 8, ARTSAKHPRESS: Issues related to the sphere of higher education of the Artsakh Republic were discussed during the meeting. President Harutyunyan stressed that the success of all long-term programs for the development and strengthening of the Artsakh Republic is conditioned by the quality of education and science, and the goal of the Artsakh authorities is to have such an educational system in Artsakh that meets all modern requirements. The guests expressed readiness to support the reform of the higher education sector. State Minister Artak Beglaryan and Minister of Education, Science, Culture and Sports Anahit Hakobyan attended the meeting.
https://www.artsakhpress.am/eng/news/164752/
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